Best TWAS P=7.32e-14 · Best GWAS P=6e-15 conditioned to 0.000288
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CYP19A1 | 0.04 | 0 | blup | 209 | 0.01 | 0.023 | 7.4 | 7.5 | 7.3e-14 | 0.51 | 0.06 | 0.28 | TRUE |
| 2 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | GLDN | 0.24 | 0 | blup | 110 | 0.06 | 0.010 | 4.4 | -6.1 | 7.9e-10 | -0.15 | 0.03 | 0.15 | TRUE |