TWAS hub - GLDN

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2620	0.0850	1.8e-07	-0.001	0.053	0.041	0.060	0.025	5.2e-01	4.4e-07	7.7e-06	7.6e-08	4.5e-04
2	GTEx	Artery Aorta	0.1920	0.0580	9.2e-07	0.034	NA	0.076	NA	0.081	5.5e-03	NA	5.4e-05	NA	3.0e-05
3	GTEx	Artery Coronary	0.1360	0.0720	7.4e-03	0.000	NA	-0.005	NA	0.002	3.3e-01	NA	5.4e-01	NA	2.7e-01
4	GTEx	Artery Tibial	0.1049	0.0414	5.5e-04	0.022	NA	0.042	NA	0.048	6.8e-03	NA	2.8e-04	NA	1.2e-04
5	GTEx	Muscle Skeletal	0.3133	0.0591	5.1e-13	0.261	NA	0.218	NA	0.248	1.5e-25	NA	4.2e-21	NA	3.5e-24
6	GTEx	Nerve Tibial	0.0951	0.0374	9.0e-04	0.062	NA	0.024	NA	0.043	3.4e-05	NA	8.0e-03	NA	4.7e-04
7	METSIM	Adipose	0.2080	0.0444	1.8e-15	0.105	0.141	0.157	0.137	0.149	2.1e-15	1.6e-20	9.4e-23	7.5e-20	1.4e-21
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0416	0.0216	4.7e-03	0.024	0.010	0.003	NA	0.007	8.3e-04	2.1e-02	1.5e-01	NA	5.4e-02
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0569	0.0282	2.4e-03	-0.002	0.013	-0.001	NA	-0.001	8.6e-01	1.0e-02	4.6e-01	NA	4.0e-01
10	TCGA	Skin Cutaneous Melanoma	0.2410	0.0990	4.8e-03	-0.003	0.060	0.030	NA	0.046	4.1e-01	1.0e-02	5.5e-02	NA	2.3e-02
11	TCGA	Thyroid Carcinoma	0.1630	0.0500	2.1e-10	0.137	0.120	0.153	NA	0.152	3.2e-13	9.5e-12	1.0e-14	NA	1.3e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Heel bone mineral density (BMD) T-score, automated (left)	3.7	8.5	37.8	2.7	-3.1	1.1	-4.6	-1.5	1.6	1.5	-0.6	-2.2	-6.1	-2.0
Sensitivity / hurt feelings	3.5	6.0	12.5	0.6	1.4	2.4	1.5	2.5	3.5	3.5	1.8	2.3	3.5	2.1
Heel T-Score	3.1	24.5	106.1	4.7	-4.0	2.0	-8.4	-0.2	4.1	5.6	1.4	-0.5	-10.3	-0.8
Diverticular disease/diverticulitis (self-reported)	3.0	3.6	8.1	-2.0	-2.8	-1.8	-1.9	-1.0	0.6	-1.8	-2.4	-2.3	-2.0	-0.8
Happiness	2.9	3.5	10.1	-0.2	-3.2	-0.0	-2.0	-1.2	1.2	-1.1	-1.8	-2.4	-2.8	-1.7
Family relationship satisfaction	2.9	3.5	11.8	-1.4	-3.4	-1.6	-2.4	-0.5	0.9	-1.2	-1.2	-1.8	-3.0	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	2.8	6.5	27.4	2.7	-2.3	0.8	-3.7	-1.6	1.5	1.5	-0.6	-2.3	-5.2	-2.2
Illnesses of father: None of the above (group 1)	2.7	3.3	9.3	-2.1	-0.2	0.3	-2.1	3.0	-1.1	1.6	2.1	1.6	0.1	2.8
Number of children fathered	2.6	3.0	5.9	1.2	2.4	2.4	0.0	1.6	1.0	1.9	2.2	2.2	1.1	1.2
Lung FVC	2.4	12.2	34.3	-5.9	-3.6	-1.5	-4.7	5.1	-2.8	1.2	2.7	0.3	-0.6	4.4
Mean time to correctly identify matches	2.4	4.7	10.4	0.1	0.7	-3.1	1.3	-2.7	-1.5	-3.2	-2.5	-2.4	-0.4	-2.8
Exposure to tobacco smoke at home	2.3	2.6	9.1	-0.9	-3.0	-2.2	-2.5	0.2	-0.2	-0.6	-0.5	-1.6	-1.9	-0.7
Body Mass Index (BMI) (2010)	2.2	3.1	10.2	-1.4	-3.2	-0.7	-2.5	1.8	-2.0	0.9	1.0	0.1	-1.4	2.0
Neuroticism (2016)	2.2	3.2	8.2	-2.6	-2.0	-1.6	-1.2	-0.7	-0.8	-1.0	-2.8	-2.9	-0.1	-1.5
Medication: Metformin	2.2	3.2	8.4	-1.4	-0.7	-1.8	-1.1	2.9	1.2	1.6	2.4	1.9	0.4	2.4
Medication: Cholesterol lowering	2.2	3.4	11.9	0.0	2.9	1.8	3.5	-0.1	-0.6	-0.8	-0.1	2.4	2.6	-0.2
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.5	12.5	-1.2	-3.5	-2.2	-2.1	1.0	2.6	1.4	0.1	-1.9	-1.3	0.3
Medication: Co-codamol	2.0	2.3	6.3	-0.6	0.6	-0.6	0.6	-2.0	-1.6	-2.4	-2.5	-1.3	-0.5	-1.8
Noisy workplace	2.0	2.5	5.8	-1.7	-1.6	-2.4	-0.4	-1.6	0.1	-1.4	-2.3	-1.8	-1.5	-1.2
BMI	1.9	10.9	33.5	-3.4	-5.8	-4.0	-5.6	1.9	0.0	2.4	0.5	-2.0	-3.4	1.0
High blood pressure (mother)	1.9	2.7	8.3	-0.1	-0.3	-2.9	-1.1	-1.0	-2.2	-2.5	-0.6	-0.9	-2.6	-0.7
Supplements: Vitamin C	1.9	2.3	7.2	-0.5	-2.7	-1.1	-2.0	-0.2	1.9	-0.3	-0.9	-0.9	-2.5	-0.5
Tinnitus: Yes, now most or all of the time	1.9	2.2	7.1	2.7	1.0	2.5	0.1	0.1	2.5	0.8	0.8	1.2	0.2	-0.9
Illnesses of mother	1.8	2.2	6.1	-0.7	0.8	2.5	1.6	0.4	2.0	2.0	-0.2	1.1	2.2	-0.2
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	5.8	2.4	1.3	1.7	1.5	-1.9	-0.1	-0.8	-1.3	-0.9	0.2	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.4	16.9	-4.1	-3.9	-2.0	-2.9	1.0	1.4	0.2	-1.3	-2.6	-1.4	1.3
Illnesses of siblings: Diabetes	1.7	2.1	5.2	-1.7	-1.8	-0.3	-1.6	1.8	2.3	1.2	1.0	0.6	-0.8	1.4
Age at First Birth	1.6	2.3	5.2	0.0	0.7	0.2	1.9	-2.3	2.2	-1.6	-2.0	-0.3	0.0	-2.1
Ulcerative Colitis	1.6	2.3	7.7	0.1	-1.4	-1.6	-2.8	0.5	-1.1	-1.9	0.6	-0.8	-2.5	0.9
Type 2 Diabetes (T2D) (2018)	1.6	3.0	9.2	-3.0	-2.1	-1.0	-1.5	2.4	0.5	2.0	1.0	0.5	0.3	2.2
Chronic bronchitis/emphysema (father)	1.6	1.9	4.4	-1.1	-0.5	0.3	0.1	-1.7	-0.2	-2.1	-1.9	-2.1	-0.9	-1.6
Alcohol intake versus 10 years previously	1.6	2.5	6.2	-0.2	-0.8	0.4	-1.8	2.4	-0.8	2.0	2.5	1.0	-0.2	2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	12.0	-3.5	-2.1	-2.0	-2.9	1.7	-1.9	-0.2	0.6	-0.5	-0.5	1.0
High cholesterol (Self-reported)	1.6	2.9	10.5	-1.1	1.1	2.1	0.5	2.0	1.6	1.0	1.1	3.2	0.7	2.3
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	4.3	1.4	0.8	1.7	1.1	-1.8	0.7	-1.4	-1.4	-2.1	0.4	-1.9
Fasting Glucose	1.5	1.8	5.7	-1.8	-2.4	-0.2	-1.6	0.4	1.2	0.3	-0.7	-1.7	-1.6	0.7
Sitting height	1.5	10.7	44.8	2.5	1.8	6.7	3.3	-2.4	5.9	1.3	-2.7	-1.6	0.8	0.9
Time employed in main current job	1.5	1.8	5.7	1.4	2.4	0.7	1.7	0.4	0.2	0.4	1.6	1.0	2.2	0.2
Standing height	1.5	14.8	76.7	0.7	0.3	3.6	4.5	-3.8	8.8	0.2	-5.0	-3.2	1.0	-0.8
Number of full brothers	1.5	1.8	6.0	-1.5	-2.5	-0.7	-1.4	1.1	1.9	0.6	0.1	0.2	-1.5	1.5
Neck or shoulder pain in last month	1.5	2.2	6.2	2.5	2.4	-0.1	1.7	0.6	-1.2	0.6	1.3	0.9	2.0	0.1
Basal cell carcinoma (self-reported)	1.5	1.8	6.3	0.5	2.5	1.6	1.8	-1.1	-0.4	-0.6	-1.0	-0.4	1.5	-1.5
Alzheimer’s Disease (in father)	1.4	1.5	4.1	-2.0	-1.4	-1.9	-1.7	1.0	-1.1	0.6	0.6	-0.6	-0.4	0.8
Height	1.4	26.5	121.0	2.1	1.6	5.2	6.9	-4.8	11.0	0.1	-6.5	-3.6	3.0	-1.7
Pack years adult smoking proportion	1.4	2.1	6.0	-0.4	-0.5	-1.4	-0.2	-1.9	-1.0	-2.4	-1.8	-0.7	-1.6	-2.0
Hand grip strength (right)	1.4	3.8	16.9	1.1	-0.5	2.6	1.9	0.5	4.1	2.7	0.4	0.4	1.7	1.6
Multivitamins +/- minerals	1.4	1.8	7.0	1.2	-0.1	0.3	0.7	-2.0	0.6	-1.7	-1.3	-1.0	-0.7	-2.6
Number of incorrect matches in round	1.4	2.3	11.9	1.6	3.5	1.1	1.7	-0.6	-1.4	-0.6	0.6	1.5	0.9	-0.1
Mouth/teeth dental problems: Loose teeth	1.4	1.6	9.6	-3.1	-0.5	-1.5	0.7	-0.6	-0.7	-1.6	-1.1	-0.7	0.1	-0.2
Heart disease (mother)	1.4	1.7	7.0	2.6	0.3	0.0	-0.4	1.3	-0.6	0.8	2.1	0.7	0.3	1.8
Leg pain on walking	1.4	1.7	6.8	-1.9	-0.9	-2.6	-1.1	-0.5	-0.7	-0.7	-1.1	-1.2	-1.5	-0.5
Supplements: Calcium	1.4	1.5	4.6	0.2	1.5	-1.3	1.7	-1.3	-1.3	-0.6	-0.9	-0.2	0.9	-2.1
Pack years of smoking	1.4	2.0	6.2	0.0	-0.0	-1.6	0.1	-1.8	-1.2	-2.5	-1.6	-0.4	-1.4	-1.9
HbA1C	1.3	1.4	4.8	-0.1	-1.1	0.7	-2.0	-0.1	1.6	-0.0	0.1	-1.6	-2.2	-0.3
Lung FEV1/FVC ratio	1.3	6.5	19.0	-3.2	-1.4	-4.4	-1.9	-1.5	-3.1	-2.8	-1.3	-1.4	-2.9	-2.1
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	4.5	0.3	0.5	0.5	1.7	1.1	0.7	1.6	1.5	1.0	2.1	0.5
Severe depression (siblings)	1.3	1.4	4.0	-0.5	-1.9	0.8	-2.0	0.2	1.6	0.5	-0.2	-0.5	-1.9	0.7
Waist circumference	1.3	4.6	14.9	-2.8	-3.9	-2.9	-2.6	0.5	1.5	0.7	-0.7	-2.2	-2.0	0.0
Arm fat percentage (right)	1.3	5.2	19.4	-2.2	-4.4	-3.7	-3.0	1.0	0.2	1.6	0.3	-1.7	-1.9	0.4
Length of working week for main job	1.3	1.5	4.0	0.6	1.1	1.1	2.0	-1.2	-1.3	-1.1	-1.3	0.3	1.6	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	4.5	1.3	0.3	2.0	0.9	1.1	1.5	1.6	0.9	0.3	2.1	1.2
Overall health rating	1.3	2.8	7.7	-2.3	-2.0	-2.8	-2.4	0.8	-1.1	-0.3	-0.3	-2.0	-1.5	-0.1
Had major operations	1.3	1.6	6.4	1.0	2.5	1.5	1.9	-0.9	0.8	-0.1	-0.5	0.2	1.4	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	14.1	1.6	-0.8	2.4	0.6	-0.9	3.8	0.5	-1.6	-1.7	-0.1	0.4
Medication: Gliclazide	1.3	1.4	4.8	0.9	1.4	1.1	2.2	-1.2	0.5	-1.1	-1.1	0.1	1.0	-1.4
Average weekly champagne plus white wine intake	1.3	1.8	4.8	1.5	0.1	0.5	-0.0	-1.8	0.3	-0.5	-1.9	-2.1	-0.9	-2.2
Mother’s age at death	1.3	1.6	4.6	0.2	1.0	-0.0	0.9	-1.9	-1.3	-2.1	-1.4	-1.2	-0.2	-1.7
Leg fat percentage (left)	1.3	4.7	16.7	-1.6	-3.9	-4.1	-3.1	1.4	-0.6	0.5	1.1	-1.0	-1.7	0.5
Irritability	1.3	2.2	5.6	0.7	0.7	0.9	2.4	-1.9	1.8	-1.1	-2.0	-0.0	1.1	-1.7
HDL Cholesterol	1.2	2.0	7.7	0.9	1.2	-0.5	1.6	1.3	0.6	2.0	1.1	1.0	2.8	0.5
Hand grip strength (left)	1.2	3.2	14.5	0.9	-0.5	2.7	1.5	0.3	3.8	2.3	-0.3	0.1	1.9	1.2
Body mass index (BMI)	1.2	4.9	15.8	-1.7	-4.0	-3.3	-3.6	1.0	0.3	1.2	0.4	-1.4	-2.5	0.7
Had other major operations	1.2	1.5	4.1	0.3	-0.5	-1.0	-0.4	-1.7	-0.1	-1.4	-1.7	-2.0	-0.8	-1.5
Forced expiratory volume in 1-second (FEV1)	1.2	4.1	15.4	-3.9	-3.2	-1.2	-1.9	1.1	2.1	0.6	-1.1	-2.1	-0.8	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	6.7	0.7	-2.4	0.4	-1.4	0.6	2.6	1.2	0.3	-1.7	-0.3	0.6
Birth weight	1.2	2.7	8.4	-1.4	-2.4	-0.8	-2.5	0.7	1.7	1.1	-0.8	-0.3	-2.9	1.3
Forced vital capacity (FVC), Best measure	1.2	4.4	14.6	-3.8	-3.6	-0.6	-2.1	0.9	1.7	0.5	-1.5	-2.7	-0.6	1.6
Body fat percentage	1.2	4.7	17.3	-2.6	-4.2	-3.5	-2.8	1.1	0.7	1.2	0.5	-1.2	-1.8	0.6
Leg fat percentage (right)	1.2	4.5	18.9	-1.6	-3.3	-4.3	-2.9	1.3	-1.4	0.4	1.1	-1.1	-1.4	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.8	-1.0	-1.0	-0.9	0.1	1.9	0.4	1.6	1.3	1.3	1.4	0.9
Arm fat percentage (left)	1.2	5.0	18.2	-2.2	-4.3	-3.4	-3.0	1.4	0.6	2.0	0.8	-1.1	-1.6	0.7
Commuting to job workplace: Walk	1.2	1.3	3.1	1.3	0.5	0.2	0.5	-1.6	1.3	-1.2	-0.8	-0.8	-1.2	-1.8
Hearing aid user	1.2	1.3	4.1	1.4	1.9	2.0	1.6	-0.8	0.8	-0.2	-0.1	1.0	-0.2	0.2
Heart attack/myocardial infarction (self-reported)	1.2	1.5	3.9	-0.2	1.4	0.0	0.9	-1.9	-0.6	-1.0	-2.0	-1.1	-0.2	-1.9
Breast Cancer	1.1	2.6	8.6	-2.3	-2.1	-0.9	-1.7	-0.8	1.0	-1.1	-1.2	-2.9	-1.0	-1.2
Blood White Count	1.1	7.8	20.7	-3.2	-3.0	-3.3	-4.5	-0.8	-1.4	0.3	0.3	-3.8	-3.9	-1.7
Trunk fat percentage	1.1	4.5	17.1	-2.8	-4.1	-2.7	-2.6	1.1	1.5	1.6	0.5	-1.2	-1.6	0.8
Hair/balding pattern: Pattern 2	1.1	1.4	3.9	0.1	-1.3	-2.0	-1.7	-0.2	0.1	-1.5	-0.5	-0.8	-2.0	0.3
Heart attack	1.1	1.4	3.4	-0.3	1.6	0.3	1.1	-1.7	-0.6	-0.8	-1.8	-1.0	0.2	-1.8
Father’s age at death	1.1	1.5	4.2	-0.9	-1.8	-1.0	-2.1	-0.4	-1.5	-0.3	-0.6	-1.2	-1.8	-0.3
Arm fat mass (right)	1.1	4.4	17.6	-1.4	-4.2	-2.7	-2.5	0.3	1.9	1.5	-0.5	-2.2	-2.0	0.5
Blood clot in the leg (DVT)	1.1	1.4	3.6	1.4	0.5	1.6	0.7	-1.3	0.8	-1.0	-1.0	-1.9	0.2	-1.7
Whole body fat mass	1.1	4.6	17.0	-2.1	-4.1	-2.5	-2.6	0.3	2.2	1.2	-0.6	-2.1	-2.0	0.5
Arm fat mass (left)	1.1	4.5	17.2	-1.5	-4.2	-2.5	-2.5	0.4	2.4	1.7	-0.5	-2.0	-2.0	0.6
Bipolar Disorder (2018)	1.0	1.6	4.8	-0.8	-0.7	-2.1	-0.2	-1.3	0.0	-2.2	-1.4	-1.2	-1.2	-0.4
Intelligence (Savage-Jansen 2018)	1.0	3.2	11.6	-0.8	-2.5	-0.6	-1.9	-1.0	1.4	1.3	-1.4	-3.4	-2.0	-1.3
Bipolar Disorder (2011)	1.0	0.9	4.4	-0.0	-0.3	-1.0	-1.1	-0.3	-2.1	-0.9	-0.9	-1.2	-0.3	0.7
Primary Biliary Cirrhosis	1.0	1.4	4.9	2.0	0.1	-0.0	-0.6	1.5	0.5	-0.0	2.2	0.6	-0.2	1.9
Chronotype (morning person)	1.0	2.3	7.0	-0.0	-1.6	-0.6	-2.2	2.3	-1.5	0.4	2.6	-0.5	0.3	1.7
Relative age of first facial hair	1.0	2.1	9.1	-0.5	1.6	2.3	2.0	0.3	-0.3	0.8	-0.5	0.4	3.0	0.8
Angina	1.0	1.3	5.1	1.0	1.5	0.8	2.2	-0.2	-0.4	-0.4	0.2	1.0	1.9	0.3
Medication for hormone replacement therapy	1.0	1.1	3.7	0.1	-1.2	-0.5	-1.9	-0.2	0.7	-1.0	-0.3	-1.3	-1.8	0.3
Age when periods started (menarche)	1.0	2.4	5.8	0.1	1.1	-0.9	0.4	-2.3	-0.3	-1.7	-2.0	-2.4	-0.9	-2.4
Stomach or abdominal pain in last month	1.0	1.2	4.1	0.3	-1.2	-1.4	-0.4	1.5	0.8	0.3	2.0	-0.3	0.4	1.5
Trunk fat mass	1.0	4.3	16.7	-2.2	-4.1	-2.2	-2.2	0.4	2.7	1.5	-0.5	-1.8	-1.8	0.6
Medication: Simvastatin	1.0	1.5	5.2	-2.3	1.5	0.9	1.2	0.1	1.2	-1.3	-0.5	1.6	0.6	-0.4
Weight	1.0	4.7	16.0	-1.3	-3.6	-1.6	-1.4	-0.8	4.0	1.1	-1.9	-2.8	-1.9	0.2
Trunk predicted mass	1.0	5.5	29.1	1.0	-1.8	0.9	0.7	-2.1	5.4	0.3	-3.2	-3.2	-1.0	-0.1
Exposure to tobacco smoke outside home	1.0	1.3	3.4	1.8	0.7	0.2	1.9	-1.5	-0.4	-1.2	-0.9	-0.5	0.5	-1.5
Qualifications: College or University degree	1.0	3.1	7.2	-0.5	-2.5	-0.2	-0.7	-2.0	2.0	0.0	-2.7	-2.2	-1.7	-2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	4.1	1.7	2.0	2.0	0.4	-0.2	0.3	0.7	-0.0	1.0	-0.1	-0.1
Leg fat mass (right)	1.0	4.0	14.6	-1.8	-3.8	-3.2	-2.6	0.6	0.8	0.9	-0.2	-1.9	-1.9	0.6
Suffer from ‘nerves’	1.0	1.6	3.9	-1.4	-1.6	-1.5	-2.0	1.0	1.6	-0.7	0.5	-1.1	-1.0	0.9
Chest pain or discomfort	1.0	1.5	3.3	-0.1	-1.0	-0.9	-0.4	-1.0	1.0	-1.4	-1.6	-1.0	-1.8	-1.8
Leg fat-free mass (right)	1.0	5.2	26.4	-0.2	-2.8	1.1	-0.7	-1.1	5.1	1.8	-2.3	-2.9	-1.6	0.4
Friendships satisfaction	1.0	1.2	6.4	-0.6	-2.5	-0.6	-1.2	0.1	0.9	-0.2	-0.3	-0.7	-1.8	-0.2
Osteoarthritis (self-reported)	1.0	1.2	5.4	-1.0	-1.1	-2.3	-0.9	-0.0	-1.2	-0.6	-0.9	-1.4	-0.6	-0.6
Leg predicted mass (right)	1.0	5.1	25.9	-0.2	-2.8	1.1	-0.7	-1.2	5.1	1.7	-2.3	-2.9	-1.6	0.3
Medication: Lisinopril	1.0	1.3	3.5	-1.1	1.3	1.2	1.1	1.2	-0.9	1.1	0.6	1.1	1.9	1.0
Fractured/broken bones in last 5 years	1.0	1.2	3.2	-0.6	1.4	-1.0	0.8	-1.0	-1.2	-1.8	-1.1	-0.7	-0.1	-1.6
Diastolic blood pressure, automated reading	1.0	3.1	7.9	-2.4	-1.0	-2.8	-1.7	2.1	-2.1	-0.7	1.7	-0.5	0.1	2.1
Alcohol drinker status: Previous	1.0	1.1	3.9	-0.9	-0.1	-1.2	0.2	1.4	-0.6	0.5	1.5	2.0	0.9	0.9
Leg fat mass (left)	1.0	3.9	15.3	-1.4	-3.9	-2.8	-2.6	0.5	1.4	0.9	-0.2	-1.8	-2.0	0.5
Bipolar Disorder or Schizophrenia	0.9	2.1	8.0	-0.0	-0.2	-0.9	-1.4	-1.9	-0.1	-1.9	-2.0	-1.1	-2.8	0.2
Depression (Nagel 2018)	0.9	1.4	6.5	1.4	-0.8	0.6	-0.8	-0.0	2.5	0.6	-0.5	-2.0	-0.4	-0.3
Schizophrenia vs Biploar Disorder	0.9	1.2	4.3	0.7	2.1	1.7	1.7	-0.9	0.6	0.1	-0.8	0.5	0.2	0.0
Ulcerative Colitis (UC)	0.9	1.7	3.9	1.5	-0.3	-2.0	-1.5	0.5	-1.2	-1.7	1.4	-0.2	-1.7	0.7
Reaction Time	0.9	1.6	3.9	-0.0	-0.1	-2.0	0.8	-1.5	-0.4	-1.9	-1.5	-1.8	-0.2	-1.4
Verbal and Numeric Reasoning (VNR)	0.9	2.3	7.8	-1.8	-2.8	-1.2	-2.3	0.6	-0.6	1.5	0.1	-1.6	-1.3	-0.2
Ever had hysterectomy (womb removed)	0.9	1.0	3.9	-0.2	-0.2	-0.3	-2.0	-0.1	-0.0	0.2	0.1	-1.9	-1.7	-0.4
Maternal smoking around birth	0.9	1.3	6.8	2.6	-0.1	1.5	1.6	-0.8	-0.3	-0.3	-0.3	-1.0	0.7	-0.8
Fed-up feelings	0.9	1.6	6.3	-1.5	-2.3	0.2	-0.6	0.8	2.5	1.4	0.0	-0.4	-0.2	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.3	0.1	-1.5	-1.0	-0.7	1.0	1.8	1.0	0.2	-1.8	0.7	0.7
Forced vital capacity (FVC)	0.9	3.6	12.6	-3.5	-2.9	0.3	-1.1	1.3	2.4	1.1	-1.0	-1.9	0.1	2.0
Trunk fat-free mass	0.9	5.4	29.3	0.9	-1.9	0.9	0.6	-2.0	5.4	0.4	-3.2	-3.2	-1.0	0.0
Hip circumference	0.9	4.0	11.3	-1.3	-3.4	-0.4	-2.4	0.5	3.0	2.6	-0.6	-1.4	-2.1	1.5
Tense / ‘highly strung’	0.9	1.5	5.0	-1.2	-0.2	-2.2	-0.5	-0.7	-0.2	-2.0	-1.0	-1.9	-0.3	-0.3
Birth weight of first child	0.9	1.7	7.1	-1.1	-2.7	0.6	-1.1	-0.6	0.7	0.6	-1.2	-2.1	-1.3	-0.4
Peak expiratory flow (PEF)	0.9	2.0	4.5	-2.1	-1.9	-0.3	-2.1	1.0	1.5	1.4	-0.4	-1.1	-1.1	1.2
Comparative body size at age 10	0.9	2.4	7.5	-2.2	-2.4	-2.7	-1.9	0.8	0.8	1.0	0.1	1.0	-1.2	-0.1
Health satisfaction	0.9	1.1	3.0	-1.7	-1.6	0.1	-1.3	1.5	-0.2	1.2	0.6	0.3	-0.2	0.8
Pulse rate, automated reading	0.9	2.8	13.6	-0.8	-1.2	-2.7	-0.6	-0.9	-1.6	-1.4	-0.8	-3.7	-0.9	-0.8
Alcohol intake frequency.	0.9	2.2	5.6	-1.0	-0.2	-1.7	-0.7	2.1	-0.4	1.1	2.4	1.6	0.3	2.3
Comparative height size at age 10	0.9	4.7	14.7	0.6	0.6	0.4	1.9	-3.1	3.8	-1.1	-3.5	-2.2	-1.3	-1.8
Number of full sisters	0.9	1.1	3.8	-1.8	-1.3	0.2	-0.3	-0.5	-0.1	-0.7	-1.3	-1.9	-0.4	-0.8
Illnesses of father: Heart disease	0.9	1.3	3.1	1.7	0.5	1.7	1.2	-1.2	1.5	-0.1	-0.7	0.2	0.2	-1.3
Whole body fat-free mass	0.9	4.9	26.8	0.6	-2.2	0.9	0.1	-1.6	5.2	1.0	-2.7	-3.0	-1.2	0.3
Average weekly red wine intake	0.9	1.3	5.0	2.2	1.0	1.0	1.3	-1.2	0.9	-1.1	-0.1	0.4	-0.1	-1.3
Back pain experienced in last month	0.9	1.4	3.7	1.4	0.8	-0.1	1.5	-0.9	1.9	-0.8	-0.8	-0.8	1.4	-1.4
Whole body water mass	0.9	5.0	26.7	0.7	-2.2	0.9	0.1	-1.7	5.2	0.9	-2.8	-3.1	-1.3	0.1
Financial situation satisfaction	0.9	1.2	3.2	0.5	-0.1	0.2	0.1	-1.3	1.4	-1.1	-1.4	-0.9	-1.3	-1.8
Basal metabolic rate	0.9	5.0	25.0	0.1	-2.8	0.2	-0.4	-1.4	5.0	1.1	-2.6	-3.2	-1.5	0.2
Arm fat-free mass (left)	0.9	4.4	18.6	0.7	-2.3	-0.0	-0.2	-1.9	4.3	0.2	-2.7	-3.1	-1.7	-0.3
Ever had prostate specific antigen (PSA) test	0.9	1.0	5.9	-1.6	1.0	2.4	0.3	-0.0	0.5	0.1	-0.5	0.9	-0.4	-0.5
Alzheimer’s Disease (including proxy)	0.8	1.2	4.1	-2.0	-1.2	-2.0	-1.3	0.4	-0.9	0.7	0.1	-0.4	-0.7	-0.0
Crohns Disease (2012)	0.8	1.3	3.0	0.2	-1.7	-0.4	-1.7	1.3	0.2	0.9	0.9	-0.7	-1.2	1.7
Number of treatments/medications taken	0.8	1.5	4.3	0.2	1.8	-0.3	1.7	0.5	-1.8	-0.1	0.8	1.2	2.1	-0.8
Frequency of depressed mood in last 2 weeks	0.8	1.2	6.2	0.9	-1.0	0.7	-0.6	-0.7	2.5	-0.2	-0.9	-1.5	-0.5	-0.2
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	4.2	-2.0	-1.1	-0.6	-1.3	-0.2	-1.3	0.1	-0.8	-0.7	-1.0	-0.8
Supplements: Zinc	0.8	0.9	3.1	-0.0	-1.0	-0.2	0.1	-0.7	1.5	0.1	-1.3	-1.8	0.1	-1.0
Leg fat-free mass (left)	0.8	4.2	21.1	-0.2	-2.5	0.5	-0.7	-1.1	4.6	1.5	-2.1	-2.9	-1.5	0.3
Average weekly fortified wine intake	0.8	0.9	3.5	1.1	0.5	0.6	-0.5	-1.1	1.9	-0.3	-0.2	-1.0	-1.5	-0.4
Taking other prescription medications	0.8	1.2	2.8	0.9	0.8	-0.3	0.2	1.5	-1.7	1.0	1.3	1.2	1.2	0.7
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	2.8	1.4	1.3	0.5	0.6	-1.1	-0.5	-1.2	-0.5	-1.7	0.0	-0.5
Qualifications: CSEs or equivalent	0.8	1.0	2.5	-1.4	-1.6	-1.6	-0.4	0.6	-0.2	-0.7	0.3	-0.5	-0.6	1.6
Leg predicted mass (left)	0.8	4.2	20.8	-0.2	-2.5	0.6	-0.6	-1.1	4.6	1.6	-2.1	-2.8	-1.4	0.4
Financial difficulties in last 2 years	0.8	1.0	2.8	-0.0	-0.6	0.4	0.1	-1.7	0.5	-1.6	-1.7	-0.1	-1.6	-0.2
Pain all over the body in last month	0.8	0.8	2.9	-0.4	-1.2	1.2	-1.7	0.1	-0.3	-0.2	-0.5	-0.9	-1.3	0.8
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.0	0.7	0.6	-0.4	0.7	0.9	1.4	1.7	1.1	1.4	1.5	1.5
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	3.8	0.9	-1.6	0.0	-1.9	0.2	1.2	1.3	0.2	-1.4	-1.6	0.5
Medication: Ventolin 100micrograms inhaler	0.8	1.0	5.0	-0.1	-2.2	-0.6	-1.5	0.8	-0.1	0.9	0.3	-0.5	-0.9	0.9
Arm fat-free mass (right)	0.8	3.9	22.1	0.9	-1.9	0.6	-0.2	-1.4	4.7	0.4	-2.4	-2.4	-1.4	0.2
Pulse wave peak to peak time	0.8	1.0	2.7	0.9	-1.7	-1.1	-0.7	0.0	1.4	-0.6	-0.2	-1.0	-1.3	0.7
Angina (self-reported)	0.8	1.1	4.8	0.9	1.3	0.4	2.2	-0.4	-0.7	-0.7	0.1	0.6	1.8	0.1
Medication: Omeprazole	0.8	0.9	2.6	0.7	1.6	0.6	1.6	0.4	0.7	0.1	1.1	0.9	1.3	-0.1
Smoking status: Previous	0.8	1.2	3.4	-1.4	1.5	1.4	1.3	-0.6	0.1	0.3	-1.8	0.0	0.8	-0.5
Ever had bowel cancer screening	0.8	1.0	3.5	1.0	0.7	0.3	-0.4	1.0	1.5	0.5	1.9	0.7	-0.3	1.2
Diabetes diagnosed by doctor	0.8	1.4	5.4	-2.3	-1.5	-1.5	-1.1	1.0	1.3	0.5	0.3	0.0	-0.6	0.9
Medication: Atorvastatin	0.8	1.0	5.0	1.3	0.4	0.3	0.7	0.8	-2.2	-0.2	1.4	0.6	0.4	0.8
Illnesses of father: High blood pressure	0.8	1.0	2.4	0.5	-0.1	-0.6	0.9	-1.6	0.3	-1.4	-1.4	-1.5	-0.1	-1.0
Arm predicted mass (left)	0.8	4.2	16.6	0.8	-2.3	-0.2	-0.3	-1.8	4.1	0.2	-2.6	-3.3	-1.6	-0.1
Schizophrenia (2018)	0.7	1.4	7.0	0.6	0.4	0.6	-1.6	-1.3	-0.1	-0.7	-1.6	-0.4	-2.6	0.6
Crohns Disease (2017)	0.7	1.6	4.0	1.3	-1.0	0.0	-0.5	1.8	0.8	2.0	1.7	0.1	0.4	2.0
Coronary Artery Disease (CAD)	0.7	0.9	2.8	1.3	0.5	-0.4	-0.9	1.7	-0.7	0.6	1.2	0.8	0.2	1.0
Waist Hip Ratio (WHR)	0.7	3.2	7.5	-1.9	0.1	-1.6	2.7	-1.0	-0.4	-2.7	-1.5	-1.0	1.8	-2.6
Vitamin and mineral supplements	0.7	0.9	3.0	-1.2	1.0	0.5	0.7	0.5	-1.2	0.7	0.1	0.0	1.2	1.7
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	7.7	0.3	-0.6	-0.5	-0.4	-0.7	2.8	-0.8	-1.0	-1.2	-0.6	-0.2
Had menopause	0.7	0.9	3.0	1.4	1.7	-1.5	0.1	-0.3	-0.9	-0.8	0.8	0.2	-0.3	-0.5
Diabetes (self-reported)	0.7	1.1	7.6	-2.8	-0.9	-0.2	-0.9	0.8	1.1	0.7	-0.1	-0.2	-0.1	0.9
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	3.4	-1.8	-1.3	1.2	-1.4	0.5	-1.1	0.6	-0.3	-0.4	-0.4	0.0
Falls in the last year	0.7	1.0	4.0	-1.0	0.2	0.8	-0.5	1.4	0.4	0.8	1.1	-0.1	0.8	2.0
Number of live births	0.7	1.0	2.5	-0.0	0.9	-1.2	0.3	-1.0	-1.3	-1.6	-1.3	-1.2	-0.5	-0.2
Pulse wave Arterial Stiffness index	0.7	0.8	2.4	-1.1	1.5	1.0	0.7	0.1	-0.7	0.8	0.1	0.9	1.3	-0.5
Breastfed as a baby	0.7	0.8	3.5	-0.6	-0.9	-1.0	-1.5	-0.1	0.4	0.6	0.2	-0.6	-1.9	-0.5
Hair/balding pattern: Pattern 4	0.7	1.7	4.1	-0.6	-0.6	-1.1	-0.4	1.7	-2.0	1.5	1.6	0.0	1.3	1.8
Ever highly irritable/argumentative for 2 days	0.7	0.9	6.4	0.3	0.0	-0.1	0.5	-0.3	2.5	0.9	-0.7	0.9	0.2	-0.8
Headache pain in last month	0.7	1.2	6.1	0.6	-0.8	-0.3	1.4	-1.3	1.0	-0.3	-0.8	-0.3	0.7	-2.5
Medication: Amlodipine	0.7	1.0	3.9	-1.2	-0.2	-2.0	0.9	-0.6	-1.0	-1.0	-0.4	-0.5	1.1	-0.9
Arm predicted mass (right)	0.7	3.7	20.8	0.6	-2.0	0.6	-0.3	-1.3	4.6	0.5	-2.2	-2.3	-1.5	0.3
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.0	-0.7	0.1	-0.0	-0.0	1.2	0.2	1.7	1.1	1.1	0.8	1.2
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.9	-1.2	0.5	0.6	0.8	1.0	-1.1	0.9	0.1	0.5	1.7	-0.0
Breast cancer (self-reported)	0.7	0.9	3.0	0.2	0.4	0.2	-0.2	-1.5	0.8	-1.0	-1.7	0.2	-1.5	-0.3
Commuting to job workplace: Public transport	0.7	0.9	3.9	-0.0	-1.6	-0.1	-1.0	-0.2	0.1	-0.4	-0.8	-2.0	-1.0	-0.4
Average weekly beer plus cider intake	0.7	1.1	4.2	-0.3	-1.1	0.4	-0.8	1.7	-0.2	0.6	1.2	0.4	0.5	2.0
Risk taking	0.7	1.1	3.2	0.7	1.5	1.6	1.3	0.0	-0.4	0.8	0.3	1.8	1.0	0.3
Commuting to job workplace: Cycle	0.7	0.8	2.8	-1.7	-0.5	0.2	0.3	-0.7	0.9	-0.5	-1.1	-1.1	-0.6	-1.2
Prostate Cancer	0.6	0.8	2.6	1.6	1.3	-0.3	1.2	-0.3	0.1	-0.1	0.7	0.9	0.5	-1.0
Rheumatoid Arthritis	0.6	0.8	2.2	1.2	-0.0	0.2	0.3	0.9	0.5	1.2	1.5	0.4	1.4	0.8
Schizophrenia (2014)	0.6	1.3	6.5	0.5	0.6	0.2	-1.3	-1.4	0.1	-1.2	-1.6	-0.3	-2.6	0.2
Triglycerides	0.6	0.9	2.7	-1.1	-1.4	-0.5	-1.0	-0.3	-0.4	-1.4	-0.6	-0.7	-1.6	-0.0
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.0	1.1	0.2	1.3	-1.4	0.9	-0.2	0.6	0.8	-0.9	0.1	-0.3
Diabetes (father)	0.6	0.8	2.9	0.7	-1.1	0.1	0.4	0.9	1.7	0.8	1.1	-0.1	1.1	0.2
Relative age voice broke	0.6	0.9	2.1	0.4	1.5	1.1	0.9	-1.2	-0.5	-1.2	-1.3	-0.8	0.4	-0.2
Fluid intelligence score	0.6	1.2	4.2	-1.1	-2.1	0.2	-1.7	0.3	0.3	1.5	-0.0	-1.4	-1.0	0.0
Neuroticism score	0.6	1.3	6.9	-1.2	-0.7	0.6	-0.6	1.0	2.6	1.4	-0.0	-0.4	0.7	0.9
Qualifications: A levels/AS levels or equivalent	0.6	1.4	6.5	0.6	-0.6	0.8	-0.2	-1.5	2.5	0.4	-1.4	-1.0	-1.3	-0.7
Depression (self-reported)	0.6	0.7	2.1	0.3	-1.1	0.4	-0.6	0.5	1.5	0.1	0.5	0.2	-1.1	1.4
Prospective memory result	0.6	0.8	3.2	1.5	0.5	-0.2	-0.1	-0.7	-1.0	-1.8	-0.0	-0.5	-0.6	-0.6
Loud music exposure frequency	0.6	0.7	1.8	0.6	1.3	-0.8	1.2	-1.3	0.1	0.2	-0.9	-0.4	0.4	-0.4
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.8	0.9	0.4	1.4	0.8	-0.1	0.6	0.7	-0.1	0.5	-0.2	1.7
Worry too long after embarrassment	0.6	1.0	4.7	0.7	-0.8	1.3	-0.9	0.2	2.2	0.9	-0.2	-0.1	-1.3	0.2
Age at first live birth	0.6	1.1	3.0	1.7	1.3	0.6	1.1	-1.2	0.3	-0.4	-1.2	0.2	-0.3	-1.7
Emphysema/chronic bronchitis	0.6	0.7	1.7	-0.6	-1.0	-0.6	-1.3	1.1	-1.0	-0.3	1.2	0.5	-0.2	0.5
Medication: Blood pressure	0.6	1.1	4.4	-1.0	1.1	-0.8	1.0	0.3	-2.1	-0.5	0.3	1.0	1.7	-0.4
Migraine (self-reported)	0.6	0.8	2.2	0.9	0.4	1.4	-0.6	-0.2	1.3	1.5	-0.5	-0.8	-0.2	-0.3
Knee pain experienced in last month	0.6	0.9	4.3	-0.2	-0.9	-2.1	-0.8	0.5	0.2	-0.3	0.5	-1.6	-0.7	0.6
Hypertension (Self-reported)	0.6	1.5	3.9	-1.3	0.4	-2.0	-0.2	1.7	-1.6	-0.4	1.8	-0.0	1.3	0.9
Loneliness, isolation	0.6	0.9	2.9	-1.7	-1.7	-0.8	-1.0	0.3	-0.3	0.1	0.1	-1.1	-0.6	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.3	0.9	-0.0	0.7	0.3	0.8	-1.1	0.1	1.5	0.8	0.7	0.3
Osteoporosis (self-reported)	0.6	0.8	3.0	-1.6	1.7	0.2	-0.6	0.1	-0.8	0.3	-0.7	-0.7	0.3	-1.0
Medication: Aspirin	0.6	0.8	2.0	-0.4	1.2	-1.4	1.2	-0.6	0.1	-1.2	-0.4	-0.1	0.7	-1.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.7	0.4	0.4	0.5	0.7	-1.3	0.8	-1.0	-1.2	-0.2	-0.8	-1.0
Medication: Blood pressure	0.6	1.1	3.3	-1.1	-0.5	-1.6	-0.7	1.5	0.1	0.2	1.8	0.2	0.4	1.1
Ever smoked	0.6	1.0	5.1	-2.3	1.2	1.2	1.1	0.0	0.7	0.3	-0.3	0.3	0.9	0.2
Number of operations (self-reported)	0.6	0.9	3.4	0.3	-0.1	0.2	-0.0	-1.6	-0.5	-0.8	-1.8	-1.3	-0.3	-0.7
Ever depressed for a whole week	0.6	0.7	2.5	0.2	0.1	1.6	0.2	-0.7	0.7	0.4	-1.4	-1.4	0.3	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.8	1.4	0.9	0.9	1.1	0.4	-0.0	0.3	1.3	0.4	1.0	0.1
Neuroticism (Nagel 2018)	0.5	1.1	7.8	-0.3	-0.5	0.8	-0.3	0.2	2.8	0.8	-1.0	-1.0	0.1	-0.2
Irritable Bowel Disease (IBD)	0.5	1.2	3.1	1.8	-0.7	-1.2	-1.2	0.9	-0.3	-0.1	1.5	-0.3	-1.1	1.5
Mean Putamen Volume	0.5	0.6	2.0	0.3	0.5	-1.4	0.9	-0.1	-0.6	0.6	0.2	0.7	0.9	-1.0
Blood Platelet Count	0.5	5.5	20.1	-2.1	-1.6	-2.3	-3.0	-1.7	0.1	-0.8	-2.2	-3.1	-4.5	-1.2
Cardiovascular Disease	0.5	1.6	5.0	-2.2	-1.0	-1.6	-1.1	2.1	-0.3	0.4	1.3	-0.5	0.5	1.1
Neuroticism	0.5	1.2	4.7	-1.3	-0.8	0.8	-0.5	1.1	2.2	1.4	-0.1	-0.4	0.8	1.2
Hearing difficulty/problems: Yes	0.5	0.8	2.3	1.3	0.2	1.5	0.3	-1.1	0.9	0.2	-1.0	-0.3	-0.6	-0.9
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.4	0.5	1.5	-0.5	0.2	0.7	-0.8	-0.3	1.1	0.5	0.8	0.7
Townsend deprivation index at recruitment	0.5	0.7	2.6	-1.6	-1.1	-0.1	0.0	-0.2	0.8	-0.5	-1.1	-0.9	-0.8	-0.4
Current tobacco smoking	0.5	0.7	1.7	-0.4	0.9	1.2	-0.7	-0.1	-1.3	-1.2	0.7	-0.1	-1.0	0.9
High blood pressure	0.5	1.5	4.6	-1.1	0.1	-2.1	-0.5	1.8	-1.1	-0.3	1.9	0.4	0.8	1.2
Past tobacco smoking	0.5	0.9	4.9	2.2	-1.3	-1.0	-1.0	0.4	-0.3	-0.0	1.1	0.0	-0.5	0.0
Mouth/teeth dental problems	0.5	0.8	2.4	0.6	0.2	0.5	-0.4	0.9	-0.6	1.3	1.3	0.7	0.1	1.6
Medication: Ramipril	0.5	0.6	4.9	-0.1	-0.3	-2.2	0.6	0.0	-0.4	-1.1	0.3	-0.0	0.5	-0.1
Hair/balding pattern: Pattern 3	0.5	0.7	1.8	-0.2	1.0	1.3	0.9	-0.3	1.1	1.2	-0.5	-0.6	0.8	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	2.1	1.4	0.5	0.4	-0.7	0.2	1.1	-0.5	0.7	0.5	-0.7	0.4
Medication: Lansoprazole	0.5	0.5	1.6	0.9	0.3	-1.2	-0.3	0.8	-1.0	-0.7	0.8	-0.1	0.3	0.5
Pulse wave reflection index	0.5	0.6	2.2	-0.1	0.5	0.2	0.8	-0.4	0.6	0.8	-0.6	1.3	0.2	-1.5
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.7	-0.6	-1.6	-0.3	0.1	0.5	1.2	1.3	0.0	0.1	0.5	-0.4
Gout (self-reported)	0.5	0.7	4.7	0.6	0.9	-0.2	-0.1	0.3	-2.2	0.5	1.0	0.7	0.1	0.3
High blood pressure (siblings)	0.5	0.7	1.6	-0.3	-0.5	-0.6	-1.1	-0.5	1.0	-0.9	-1.0	-1.3	-1.1	0.4
Medication: Allopurinol	0.5	0.7	2.9	1.0	1.4	0.5	0.0	0.4	-1.7	0.3	0.9	0.7	0.2	0.2
Mood swings	0.5	0.8	6.2	0.5	0.2	0.8	0.6	-0.3	2.5	1.1	-0.1	0.0	0.4	-0.4
Qualifications: nursing, teaching	0.5	0.7	2.1	-1.5	-0.6	-1.4	0.0	-0.2	0.6	1.4	-1.2	-0.2	0.4	0.1
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.3	-0.1	0.7	0.7	1.5	-0.6	0.5	-0.9	-1.0	0.2	1.0	-1.2
Medication for cholesterol	0.5	0.8	2.4	0.8	0.3	1.1	1.5	-0.5	-0.8	0.8	-0.8	0.5	1.3	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.7	1.4	0.7	0.9	-0.4	-0.1	0.2	-0.3	0.4	-1.6	0.0	0.6
Mineral and other dietary supplements	0.5	0.7	1.6	-1.0	0.5	1.3	0.7	-1.2	0.8	-0.4	-1.2	0.1	-0.8	-0.3
Number of self-reported non-cancer illnesses	0.5	0.8	3.9	0.1	0.2	-0.8	-0.3	1.1	-2.0	-0.3	1.2	0.5	1.2	-0.3
Supplements: Fish oil (including cod liver oil)	0.5	0.7	1.9	0.4	-0.5	-1.1	-0.9	1.4	-0.5	0.1	1.2	0.2	0.7	0.7
Age started oral contraceptive pill	0.5	0.6	3.1	-0.0	0.8	-0.6	1.0	-0.1	-1.8	0.0	0.2	0.8	0.7	0.1
Cholesterol lowering medication	0.5	0.7	1.9	-1.1	0.6	0.9	-0.9	0.1	1.4	-0.6	-0.1	0.5	-1.4	-0.4
Depressed Affect (Nagel 2018)	0.4	0.8	4.9	-0.2	-0.7	0.8	-0.0	0.5	2.2	1.5	-0.1	-0.3	0.1	-0.1
Major Depression (MDD)	0.4	0.5	2.3	-0.4	-0.3	-0.5	0.2	-0.8	-0.1	-0.1	-1.2	-1.5	-0.1	-1.0
Ovarian Cancer	0.4	0.5	2.4	1.5	0.8	1.1	0.5	-0.4	0.4	0.3	0.0	-0.3	0.5	-0.8
Blood Eosinophil Count	0.4	3.1	9.7	-3.1	-2.3	-2.7	-1.7	1.5	-1.6	1.5	0.9	0.8	-0.9	0.3
Smoking Status	0.4	1.0	4.4	-2.1	1.5	1.1	0.4	-0.3	-1.2	-0.8	-0.5	-0.1	-0.1	0.7
Respiratory disease	0.4	0.8	4.3	-0.2	-0.5	0.2	-1.1	0.9	-2.1	0.6	0.9	0.6	-0.8	0.5
Impedance of leg (right)	0.4	1.9	4.9	-0.8	1.4	-1.3	1.8	0.6	-1.9	-1.5	0.8	1.0	2.2	0.5
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	2.2	1.0	-0.2	-0.5	-0.2	-0.5	-0.3	-0.5	-0.8	-1.5	-0.2	-0.2
Serious illness, injury or assault to yourself	0.4	0.5	2.3	-1.3	0.4	-0.3	0.2	-0.2	-1.5	-0.4	-0.8	0.4	0.2	-0.5
Medication: Atenolol	0.4	0.5	1.8	-0.2	0.5	-0.6	0.2	-0.7	0.6	-1.3	-0.1	0.9	-0.5	-0.8
Hearing difficulty/problems with background noise	0.4	0.6	1.7	1.3	1.2	1.3	0.2	-0.8	-0.3	0.1	-0.4	0.5	-0.8	-0.3
Qualifications: None of the above	0.4	0.9	2.5	0.3	0.8	-0.2	-0.8	1.2	-0.6	-0.8	1.6	1.1	-0.9	1.4
Allergy	0.4	0.9	3.3	1.2	-0.3	-1.8	1.3	-0.6	1.4	-0.9	-0.1	0.2	0.6	-0.5
Worrier / anxious feelings	0.4	0.7	2.8	-0.2	0.1	0.3	-0.2	-0.6	1.7	-0.2	-1.4	-1.3	-0.1	-0.8
Pulse rate	0.4	0.7	3.6	-0.5	0.2	-1.2	-0.7	-0.0	-1.9	-0.5	0.2	-1.2	-0.6	0.1
Lung cancer (father)	0.4	0.5	2.0	0.1	0.4	1.4	-0.1	0.9	-0.3	0.4	1.2	-0.4	0.6	0.6
Impedance of arm (left)	0.4	1.7	5.1	-1.8	0.8	0.6	2.0	0.8	0.7	1.2	0.8	1.4	2.2	0.6
Medication: Paracetamol	0.4	0.6	1.7	-0.6	-1.1	0.6	-1.3	0.8	0.9	1.1	0.5	-0.2	0.1	0.1
Wheeze or whistling in the chest in last year	0.4	0.8	3.0	-1.7	-1.3	-0.9	-0.5	0.1	-0.7	-0.9	-0.6	-0.9	-0.4	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.3	-0.8	-0.7	1.1	0.0	-0.5	0.0	-1.1	-0.8	-0.4	-0.7	0.0
Shortness of breath walking on level ground	0.4	0.4	1.7	-1.3	0.0	-0.4	-0.5	0.8	-0.8	0.5	0.5	0.5	0.0	0.7
Medication: Seretide 50 evohaler	0.4	0.5	1.7	0.3	0.5	0.6	0.8	-1.0	0.1	-0.9	-1.3	-0.2	-0.1	-0.3
Age at last live birth	0.4	0.6	1.5	0.7	-0.1	-0.9	0.7	-1.1	1.0	-0.2	-1.2	-0.4	-0.7	-0.7
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.5	-0.4	-1.2	-0.3	-0.4	-0.7	0.5	-0.7	-0.8	-0.2	-1.1	-0.3
Smoking status: Current	0.4	0.7	1.7	-0.4	0.6	0.5	-0.8	0.2	-1.3	-1.2	1.1	-0.0	-1.0	1.0
Miserableness	0.4	0.7	2.7	0.8	0.2	-0.1	1.5	0.3	1.0	1.0	0.0	0.5	1.6	-0.4
Ever taken oral contraceptive pill	0.4	0.5	1.9	-1.0	-1.4	0.3	0.2	0.4	-0.5	0.7	-0.1	-0.0	1.1	0.2
Medication: Paracetamol	0.4	0.6	2.8	-0.9	-1.3	0.2	-1.7	0.5	0.1	0.8	-0.1	-0.4	-0.6	0.3
Vascular/heart problems diagnosed by doctor	0.4	1.2	4.1	0.8	-0.2	2.0	0.4	-1.6	1.1	0.3	-1.9	-0.3	-0.8	-0.8
Pain experienced in last month	0.4	0.7	2.9	-1.7	0.0	0.6	-0.6	0.0	0.3	0.1	-1.2	1.1	-0.8	1.0
Worry (Nagel 2018)	0.3	0.6	2.3	-0.4	-0.2	-0.2	-0.9	0.1	1.5	-0.7	-1.1	-1.4	-0.4	-0.0
LDL Cholesterol	0.3	0.4	3.1	0.6	-0.5	-0.3	-0.3	0.3	1.8	0.6	0.6	-0.3	0.4	-0.0
Allergy or Eczema	0.3	0.7	2.3	-1.5	1.0	1.0	-0.7	0.6	-0.8	0.9	0.5	0.3	-0.3	0.8
Average weekly spirits intake	0.3	0.4	1.3	0.7	0.7	0.3	0.7	-1.1	-0.1	-0.7	-1.0	-0.4	-0.1	-0.5
Systolic blood pressure, automated reading	0.3	1.0	3.8	1.0	0.1	-0.3	-0.7	1.4	-0.8	-0.0	1.9	0.1	0.8	1.4
Diabetes (mother)	0.3	0.4	1.4	1.2	-0.9	-0.0	-0.7	0.1	-0.3	-0.1	-0.1	-0.9	-0.7	-0.1
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.5	-1.2	0.4	0.9	-1.2	0.6	-0.9	1.0	0.2	0.1	-0.9	0.8
Supplements: Glucosamine	0.3	0.5	2.8	0.4	-0.4	-0.7	0.5	0.2	-1.7	0.0	0.1	-0.4	0.9	-0.3
Medication: Levothyroxine sodium	0.3	0.6	2.6	0.0	0.2	1.6	0.3	-0.7	1.3	-0.5	-0.4	0.4	-0.2	-0.9
Mouth/teeth dental problems: Dentures	0.3	0.5	2.1	0.8	1.2	-0.3	0.2	-0.5	0.4	-1.4	-0.2	-0.2	-0.3	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.2	-0.4	0.9	-0.0	1.0	-0.4	1.1	-0.2	-0.2	0.8	0.1	-0.2
Glaucoma (self-reported)	0.3	0.4	2.1	-0.6	-0.1	-0.2	0.4	-0.5	1.4	-0.6	-0.7	-0.0	-0.4	0.1
Medication: Ibuprofen	0.3	0.3	1.8	-0.6	0.7	-0.1	0.7	-0.3	1.3	0.3	-0.2	0.5	-0.2	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.1	0.5	0.2	-0.1	0.5	-0.5	-0.2	-0.8	-0.6	-1.1	0.6	-0.8
Medication: Aspirin	0.3	0.4	1.7	-0.7	1.0	-1.3	0.3	0.0	0.1	-0.7	-0.2	-0.3	0.4	-0.4
Eye problems/disorders: Cataract	0.3	0.3	1.1	0.1	0.4	-0.7	-0.4	0.6	-0.3	1.1	0.4	-0.2	0.7	0.3
Wears glasses or contact lenses	0.3	0.4	1.3	1.1	0.1	0.2	-0.6	-0.0	-0.9	-0.9	0.6	0.2	-0.4	-0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.4	0.5	0.9	0.4	-0.0	-0.2	0.8	0.7	-0.2	-1.2	0.3	-0.6
Medication: Bendroflumethiazide	0.3	0.5	1.8	-0.3	-0.3	-0.9	-0.8	0.8	-1.0	-0.2	1.3	0.1	-0.2	0.6
Alcohol drinker status: Never	0.3	0.4	1.0	-1.0	-0.3	-0.5	-0.8	0.5	-0.9	0.4	0.5	-0.8	-0.0	-0.1
Heart disease (siblings)	0.3	0.4	1.0	0.5	-0.9	0.6	0.6	-0.3	0.8	-0.6	-0.0	-0.0	0.4	-1.0
Alzheimer’s Disease (in mother)	0.2	0.2	0.8	-0.5	0.2	-0.4	0.3	0.4	-0.2	0.7	0.5	0.2	0.9	-0.1
Systolic Blood Pressure	0.2	1.0	3.2	0.2	-1.1	-0.3	-0.1	1.4	-0.5	0.2	1.5	-0.3	1.8	1.2
Hypothyroidism (self reported)	0.2	0.6	1.6	0.2	-0.1	0.9	0.8	0.2	-0.0	1.3	0.6	1.2	1.1	-0.4
Tanning	0.2	1.9	6.2	-0.7	2.5	1.6	0.8	0.8	-1.0	0.4	0.8	2.0	1.9	0.8
Impedance of leg (left)	0.2	1.1	3.1	-1.1	0.8	-0.7	1.5	0.6	-0.8	-1.3	0.7	1.1	1.8	0.4
Alcohol usually taken with meals	0.2	0.4	2.0	0.8	0.1	-0.2	-0.5	-0.5	0.3	0.1	-0.3	-1.4	-0.7	-0.6
Illnesses of siblings	0.2	0.3	1.2	1.1	0.6	0.8	0.6	-0.3	-0.6	-0.1	0.1	0.2	0.3	-0.5
Impedance of arm (right)	0.2	1.1	4.2	-1.9	0.7	0.0	2.0	0.2	0.1	0.6	-0.1	0.5	1.9	-0.1
Asthma	0.2	0.5	1.8	-0.3	-0.5	0.6	-1.2	0.3	-0.4	0.5	0.3	0.1	-1.4	0.8
Eye problems/disorders: None of the above	0.2	0.2	0.9	-0.1	-0.7	0.6	-0.5	-0.1	0.0	-0.4	-0.4	0.0	-0.9	0.2
Medication for pain relief, constipation, heartburn	0.2	0.3	1.7	-0.5	-1.3	-0.0	-0.6	-0.0	-0.6	-0.0	-0.5	-0.0	-0.5	0.5
Long-standing illness, disability or infirmity	0.2	0.4	0.9	-0.5	-0.9	-0.0	-0.8	0.4	0.9	0.1	-0.7	-0.9	-0.1	-0.0
Asthma (self-reported)	0.2	0.4	0.8	-0.1	-0.4	0.8	-0.9	0.4	-0.4	0.7	0.5	0.2	-0.9	0.9
Guilty feelings	0.2	0.3	1.4	0.4	-0.5	1.0	-0.1	0.1	1.2	0.4	-0.3	-0.4	0.0	-0.2
Myopia	0.2	0.3	1.0	0.5	-0.4	-1.0	-0.5	0.4	0.4	-0.5	0.6	0.5	-0.4	0.3
Impedance of whole body	0.2	1.3	4.6	-1.5	1.3	0.3	2.1	0.2	-0.2	-0.5	0.3	1.1	1.9	0.1
Lupus	0.1	0.2	0.6	0.2	0.8	-0.1	0.3	-0.4	0.3	0.2	-0.5	0.7	0.3	0.2
Blood Red Count	0.1	0.7	3.1	0.7	0.4	-1.8	1.1	0.1	1.3	0.5	0.7	0.2	0.5	-0.7
Nervous feelings	0.1	0.2	0.9	-0.8	-0.3	-0.2	-1.0	0.2	0.4	-0.3	-0.4	-0.5	-0.4	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.8	0.1	-0.5	0.9	-0.2	-0.2	0.7	0.2	-0.0	0.5	-0.3	-0.4
Unable to work because of sickness or disability	0.1	0.2	1.2	0.0	0.0	1.1	-0.1	0.3	-0.4	0.4	-0.2	0.1	-0.1	-0.2
Hair Pigment	0.0	0.5	1.4	-0.6	1.0	0.3	-0.1	-0.8	-0.8	-1.2	-0.4	-0.5	-0.7	-0.3

Hub : Genes

GLDN

Models

Trait associations