Best TWAS P=9.35e-20 · Best GWAS P=3.03e-25 conditioned to 0.007
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | SMG6 | 0.24 | 0.03 | enet | 16 | 0.05 | 1.3e-02 | 1.2 | 5.5 | 3.0e-08 | -0.51 | 0.04 | 0.63 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMG6 | 0.03 | 0.01 | blup | 144 | 0.01 | 4.8e-03 | 6.6 | 9.1 | 9.3e-20 | -0.67 | 0.10 | 0.58 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SMG6 | 0.08 | 0.05 | blup | 144 | 0.07 | 1.3e-04 | 7.0 | 8.3 | 9.5e-17 | -0.71 | 0.35 | 0.45 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | SRR | 0.35 | 0.07 | enet | 11 | 0.14 | 1.1e-05 | 1.5 | -5.5 | 5.0e-08 | 0.65 | 0.02 | 0.93 | FALSE |