Best TWAS P=1.56e-08 · Best GWAS P=5.58e-09 conditioned to 0.0919
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Nucleus accumbens basal ganglia | CORO6 | 0.11 | 0.10 | lasso | 2 | 0.05 | 2.2e-02 | 4.9 | -5.6 | 2.6e-08 | 0.95 | 0.03 | 0.89 | FALSE |
2 | METSIM | Adipose | CORO6 | 0.02 | 0.02 | bslmm | 314 | 0.01 | 1.7e-02 | 4.3 | -5.6 | 2.6e-08 | 0.85 | 0.02 | 0.95 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | GIT1 | 0.06 | 0.05 | blup | 47 | 0.05 | 5.2e-06 | -4.9 | 5.7 | 1.6e-08 | -0.90 | 0.01 | 0.99 | TRUE |