Best TWAS P=3.1e-10 · Best GWAS P=4.79e-13 conditioned to 0.000356
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | CD109 | 0.32 | 0.22 | enet | 17 | 0.23 | 5.9e-13 | 5.4 | -5.7 | 1.6e-08 | 0.61 | 0.89 | 0.11 | FALSE |
| 2 | GTEx | Pancreas | CD109 | 0.18 | 0.07 | lasso | 5 | 0.07 | 5.0e-04 | -6.7 | -6.3 | 3.1e-10 | 0.88 | 0.04 | 0.88 | TRUE |
| 3 | GTEx | Spleen | CD109 | 0.27 | 0.02 | lasso | 4 | 0.02 | 7.6e-02 | 6.8 | -6.2 | 4.6e-10 | 0.78 | 0.03 | 0.51 | FALSE |