Best TWAS P=6.89e-74 · Best GWAS P=4.5e-88 conditioned to 9.21e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | RNF146 | 0.01 | 0.00 | bslmm | 323 | 0.00 | 4.8e-02 | 0.56 | -7.5 | 8.2e-14 | -0.40 | 0.05 | 0.11 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RSPO3 | 0.02 | 0.02 | blup | 60 | 0.02 | 2.8e-04 | 15.60 | 16.9 | 4.1e-64 | 0.86 | 0.10 | 0.70 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RSPO3 | 0.02 | 0.03 | blup | 60 | 0.02 | 1.3e-03 | 19.20 | 18.2 | 6.9e-74 | 0.92 | 0.02 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RSPO3 | 0.06 | 0.02 | blup | 60 | 0.04 | 9.3e-05 | 19.20 | 15.4 | 3.1e-53 | 0.82 | 0.01 | 0.97 | FALSE |