[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (right) :

chr7:91,380,845-93,160,671

Best TWAS P=6.33e-10 · Best GWAS P=2.58e-09 conditioned to 0.285

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum GATAD1 0.12 0.08 lasso 5 0.06 7.5e-04 -5.5 5.3 9.7e-08 -0.58 0.24 0.72 FALSE
2 GTEx Adrenal Gland GATAD1 0.40 0.22 lasso 7 0.25 2.0e-09 -5.5 5.9 3.9e-09 -0.63 0.07 0.91 FALSE
3 GTEx Artery Aorta GATAD1 0.09 0.08 enet 4 0.07 7.4e-05 -5.5 5.1 3.0e-07 -0.56 0.13 0.76 FALSE
4 GTEx Artery Coronary GATAD1 0.12 0.15 lasso 3 0.12 8.0e-05 -5.0 5.4 7.3e-08 -0.61 0.10 0.59 FALSE
5 GTEx Brain Caudate basal ganglia GATAD1 0.21 0.09 lasso 4 0.08 2.3e-03 -3.9 5.3 1.2e-07 -0.62 0.05 0.56 FALSE
6 GTEx Cells Transformed fibroblasts GATAD1 0.23 0.20 lasso 4 0.22 1.4e-16 -5.5 6.0 2.6e-09 -0.72 0.05 0.95 FALSE
7 GTEx Colon Transverse GATAD1 0.13 0.00 enet 16 0.05 3.0e-03 -5.5 6.1 1.3e-09 -0.58 0.09 0.62 FALSE
8 GTEx Esophagus Muscularis GATAD1 0.18 0.10 enet 33 0.13 1.6e-08 -5.5 5.3 1.5e-07 -0.46 0.15 0.84 FALSE
9 GTEx Lung GATAD1 0.15 0.12 lasso 2 0.11 1.1e-08 -5.5 5.5 4.9e-08 -0.60 0.05 0.95 FALSE
10 GTEx Nerve Tibial GATAD1 0.30 0.19 lasso 5 0.23 1.8e-16 -5.5 5.1 2.7e-07 -0.51 0.05 0.95 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic GATAD1 0.22 0.27 lasso 4 0.26 1.1e-14 -5.5 5.5 3.9e-08 -0.60 0.06 0.94 FALSE
12 GTEx Skin Sun Exposed Lower leg GATAD1 0.30 0.10 enet 14 0.16 7.0e-13 -5.5 5.3 9.8e-08 -0.50 0.08 0.92 FALSE
13 GTEx Stomach GATAD1 0.30 0.13 lasso 5 0.15 8.6e-08 -5.5 5.3 1.2e-07 -0.59 0.10 0.89 FALSE
14 GTEx Testis CDK6 0.10 0.10 lasso 3 0.09 8.0e-05 -5.9 6.2 6.3e-10 -0.88 0.01 0.98 TRUE
15 GTEx Thyroid GATAD1 0.18 0.06 lasso 4 0.06 3.3e-05 -5.5 5.2 2.5e-07 -0.55 0.11 0.89 FALSE