Best TWAS P=6.33e-10 · Best GWAS P=2.58e-09 conditioned to 0.285
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | GATAD1 | 0.12 | 0.08 | lasso | 5 | 0.06 | 7.5e-04 | -5.5 | 5.3 | 9.7e-08 | -0.58 | 0.24 | 0.72 | FALSE |
2 | GTEx | Adrenal Gland | GATAD1 | 0.40 | 0.22 | lasso | 7 | 0.25 | 2.0e-09 | -5.5 | 5.9 | 3.9e-09 | -0.63 | 0.07 | 0.91 | FALSE |
3 | GTEx | Artery Aorta | GATAD1 | 0.09 | 0.08 | enet | 4 | 0.07 | 7.4e-05 | -5.5 | 5.1 | 3.0e-07 | -0.56 | 0.13 | 0.76 | FALSE |
4 | GTEx | Artery Coronary | GATAD1 | 0.12 | 0.15 | lasso | 3 | 0.12 | 8.0e-05 | -5.0 | 5.4 | 7.3e-08 | -0.61 | 0.10 | 0.59 | FALSE |
5 | GTEx | Brain Caudate basal ganglia | GATAD1 | 0.21 | 0.09 | lasso | 4 | 0.08 | 2.3e-03 | -3.9 | 5.3 | 1.2e-07 | -0.62 | 0.05 | 0.56 | FALSE |
6 | GTEx | Cells Transformed fibroblasts | GATAD1 | 0.23 | 0.20 | lasso | 4 | 0.22 | 1.4e-16 | -5.5 | 6.0 | 2.6e-09 | -0.72 | 0.05 | 0.95 | FALSE |
7 | GTEx | Colon Transverse | GATAD1 | 0.13 | 0.00 | enet | 16 | 0.05 | 3.0e-03 | -5.5 | 6.1 | 1.3e-09 | -0.58 | 0.09 | 0.62 | FALSE |
8 | GTEx | Esophagus Muscularis | GATAD1 | 0.18 | 0.10 | enet | 33 | 0.13 | 1.6e-08 | -5.5 | 5.3 | 1.5e-07 | -0.46 | 0.15 | 0.84 | FALSE |
9 | GTEx | Lung | GATAD1 | 0.15 | 0.12 | lasso | 2 | 0.11 | 1.1e-08 | -5.5 | 5.5 | 4.9e-08 | -0.60 | 0.05 | 0.95 | FALSE |
10 | GTEx | Nerve Tibial | GATAD1 | 0.30 | 0.19 | lasso | 5 | 0.23 | 1.8e-16 | -5.5 | 5.1 | 2.7e-07 | -0.51 | 0.05 | 0.95 | FALSE |
11 | GTEx | Skin Not Sun Exposed Suprapubic | GATAD1 | 0.22 | 0.27 | lasso | 4 | 0.26 | 1.1e-14 | -5.5 | 5.5 | 3.9e-08 | -0.60 | 0.06 | 0.94 | FALSE |
12 | GTEx | Skin Sun Exposed Lower leg | GATAD1 | 0.30 | 0.10 | enet | 14 | 0.16 | 7.0e-13 | -5.5 | 5.3 | 9.8e-08 | -0.50 | 0.08 | 0.92 | FALSE |
13 | GTEx | Stomach | GATAD1 | 0.30 | 0.13 | lasso | 5 | 0.15 | 8.6e-08 | -5.5 | 5.3 | 1.2e-07 | -0.59 | 0.10 | 0.89 | FALSE |
14 | GTEx | Testis | CDK6 | 0.10 | 0.10 | lasso | 3 | 0.09 | 8.0e-05 | -5.9 | 6.2 | 6.3e-10 | -0.88 | 0.01 | 0.98 | TRUE |
15 | GTEx | Thyroid | GATAD1 | 0.18 | 0.06 | lasso | 4 | 0.06 | 3.3e-05 | -5.5 | 5.2 | 2.5e-07 | -0.55 | 0.11 | 0.89 | FALSE |