[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (right) : ← →

chr7:119,892,061-121,729,795

Best TWAS P=1.81e-235 · Best GWAS P=0 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WNT16 0.09 0.04 enet 32 0.04 8.1e-06 -12.2 -9.8 8.9e-23 -0.19 0.81 0.06 FALSE
2 GTEx Adipose Subcutaneous CPED1 0.10 0.02 enet 26 0.04 6.2e-04 17.2 21.9 1.5e-106 0.35 0.42 0.23 TRUE
3 GTEx Artery Tibial CPED1 0.08 0.00 lasso 4 0.00 1.4e-01 35.7 32.8 1.8e-235 0.86 0.03 0.91 TRUE
4 GTEx Cells Transformed fibroblasts CPED1 0.20 0.12 lasso 5 0.16 7.6e-12 20.4 19.7 2.8e-86 0.27 1.00 0.00 FALSE
5 GTEx Nerve Tibial CPED1 0.09 0.03 lasso 3 0.06 6.4e-05 19.6 14.1 2.3e-45 0.16 0.10 0.04 TRUE
6 GTEx Skin Not Sun Exposed Suprapubic FAM3C 0.15 0.09 lasso 7 0.10 6.2e-06 -13.1 14.7 8.4e-49 0.27 0.75 0.09 TRUE
7 GTEx Skin Sun Exposed Lower leg CPED1 0.05 0.01 lasso 4 0.02 1.3e-02 2.5 6.1 9.0e-10 0.04 0.27 0.04 TRUE
8 GTEx Skin Sun Exposed Lower leg FAM3C 0.16 0.07 enet 27 0.10 1.6e-08 -13.8 22.6 7.0e-113 0.47 0.66 0.32 TRUE
9 METSIM Adipose FAM3C 0.12 0.13 bslmm 376 0.13 7.0e-19 -16.0 17.9 9.6e-72 0.39 1.00 0.00 FALSE
10 METSIM Adipose ING3 0.02 0.00 blup 352 0.00 6.0e-02 1.6 6.5 9.7e-11 0.05 0.06 0.03 FALSE
11 NTR Blood C7orf58 0.04 0.02 lasso 7 0.03 9.5e-10 20.7 14.6 2.1e-48 0.19 1.00 0.00 TRUE
12 ROSMAP Brain Pre-frontal Cortex CPED1 0.05 0.01 blup 447 0.03 6.1e-05 1.7 -21.8 2.1e-105 -0.39 0.37 0.27 FALSE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C7orf58 0.08 0.01 blup 158 0.01 5.1e-02 21.4 21.5 1.0e-102 0.45 0.05 0.23 FALSE