[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (right) :

chr11:59,239,839-60,645,214

Best TWAS P=3.31e-10 · Best GWAS P=1.31e-10 conditioned to 0.00163

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Whole Blood MS4A6A 0.05 0.03 lasso 5 0.03 6.1e-04 -5.1 5.2 2.2e-07 -0.62 0.58 0.28 FALSE
2 YFS Blood MS4A6A 0.13 0.10 enet 33 0.11 2.5e-35 -5.1 5.8 5.8e-09 -0.78 0.80 0.20 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma MS4A4A 0.04 0.03 blup 79 0.04 7.2e-08 5.5 6.3 3.3e-10 -0.64 0.56 0.44 TRUE
4 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MS4A7 0.02 0.00 blup 77 0.00 1.2e-01 -3.7 5.3 9.1e-08 -0.22 0.03 0.59 FALSE
5 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MS4A6A 0.05 0.01 enet 10 0.03 6.6e-03 5.6 5.7 1.1e-08 -0.36 0.01 0.78 FALSE
6 The Cancer Genome Atlas Prostate Adenocarcinoma MS4A4A 0.07 0.03 blup 79 0.04 2.8e-05 5.5 5.2 2.1e-07 -0.47 0.45 0.54 FALSE
7 The Cancer Genome Atlas Stomach Adenocarcinoma MS4A2 0.04 0.04 blup 55 0.04 8.2e-04 -4.9 -5.4 7.9e-08 0.58 0.13 0.64 FALSE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors MS4A4A 0.16 0.02 blup 78 0.03 2.7e-02 5.5 5.5 3.4e-08 -0.45 0.02 0.10 FALSE