Best TWAS P=1.42e-10 · Best GWAS P=1.42e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | SRP54 | 0.10 | 0.14 | lasso | 1 | 0.11 | 8.8e-07 | -6.4 | -6.4 | 1.4e-10 | 1.00 | 0.00 | 1.00 | TRUE |
2 | GTEx | Cells EBV-transformed lymphocytes | SRP54 | 0.19 | 0.06 | enet | 11 | 0.05 | 9.1e-03 | -6.4 | -5.6 | 2.0e-08 | 0.78 | 0.01 | 0.93 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | SRP54 | 0.29 | 0.24 | enet | 18 | 0.21 | 1.9e-15 | -6.4 | -6.3 | 2.3e-10 | 0.97 | 0.00 | 1.00 | FALSE |
4 | NTR | Blood | FAM177A1 | 0.02 | 0.00 | blup | 381 | 0.01 | 6.0e-04 | 4.0 | -5.3 | 8.6e-08 | 0.67 | 0.11 | 0.33 | FALSE |