Hub : Genes

SRP54

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Visceral Omentum 0.091 0.0390 4.0e-03 0.009 NA 0.018 NA 0.010 1.1e-01 NA 3.8e-02 NA 9.6e-02
2 GTEx Artery Aorta 0.095 0.0400 2.1e-03 0.138 NA 0.086 NA 0.113 4.9e-08 NA 1.8e-05 NA 8.8e-07
3 GTEx Cells EBV-transformed lymphocytes 0.185 0.0670 1.1e-03 0.061 NA 0.051 NA 0.004 4.9e-03 NA 9.1e-03 NA 2.4e-01
4 GTEx Cells Transformed fibroblasts 0.289 0.0700 3.0e-13 0.245 NA 0.207 NA 0.126 2.1e-18 NA 1.9e-15 NA 1.2e-09
5 GTEx Esophagus Mucosa 0.132 0.0460 2.8e-04 0.055 NA 0.054 NA 0.054 1.5e-04 NA 1.7e-04 NA 1.6e-04
6 GTEx Heart Atrial Appendage 0.141 0.0620 6.6e-03 0.020 NA 0.018 NA 0.017 4.3e-02 NA 4.9e-02 NA 5.4e-02
7 GTEx Nerve Tibial 0.162 0.0479 8.7e-06 0.020 NA 0.085 NA 0.065 1.5e-02 NA 1.3e-06 NA 2.2e-05
8 YFS Blood 0.124 0.0244 0.0e+00 0.137 0.134 0.144 0.141 0.147 1.2e-42 1.6e-41 1.0e-44 7.3e-44 1.4e-45
9 TCGA Thyroid Carcinoma 0.066 0.0380 2.8e-03 -0.002 0.026 0.016 NA 0.008 6.3e-01 1.3e-03 9.6e-03 NA 4.7e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 1.3 2.1 4.8 1.9 1.3 1.6 1.6 -0.6 0.4 2.2 1.7 -0.6
Bipolar Disorder or Schizophrenia 2.7 6.5 11.9 3.5 3.0 2.5 3.1 -1.1 3.4 2.7 1.0 0.8
Depressed Affect (Nagel 2018) 0.2 0.5 1.3 -0.3 -0.2 -1.0 -0.7 1.1 0.8 -0.2 -0.6 -0.3
Depression (Nagel 2018) 1.1 1.6 6.2 -1.0 -0.6 -1.3 -1.6 2.5 1.1 0.3 -0.7 -0.8
Intelligence (Savage-Jansen 2018) 0.7 2.1 9.4 -1.3 -1.1 -3.1 -1.3 -1.6 0.6 -0.7 -1.2 -0.5
Neuroticism (Nagel 2018) 0.1 0.3 1.1 0.2 0.0 -0.4 -0.4 0.7 1.0 0.4 0.2 -0.6
Schizophrenia (2018) 2.7 5.5 16.0 2.9 2.8 2.0 2.8 -0.9 4.0 1.7 -0.1 1.5
Schizophrenia vs Biploar Disorder 1.0 1.4 3.1 1.7 0.8 0.1 1.1 -1.3 1.8 1.0 -0.6 1.1
Worry (Nagel 2018) 0.1 0.1 0.4 -0.1 -0.1 0.3 -0.4 0.3 0.1 -0.5 -0.1 -0.6
Alzheimer’s Disease (in mother) 2.1 2.4 3.9 -1.9 -1.7 -1.0 -1.6 1.4 -0.8 -2.0 -1.7 1.5
Alzheimer’s Disease (in father) 2.9 3.2 7.2 1.0 2.7 1.1 1.9 1.8 2.4 0.9 -1.3 2.1
Alzheimer’s Disease (including proxy) 1.4 2.1 5.5 -1.3 -0.1 -0.3 -0.6 1.9 -0.0 -1.9 -2.3 2.0
Crohns Disease (2017) 1.1 2.4 8.9 1.2 0.2 -1.0 0.1 0.4 1.5 0.5 -3.0 2.8
Irritable Bowel Disease (IBD) 1.5 3.6 13.5 1.0 0.6 -0.7 0.1 0.9 1.8 -0.3 -3.7 3.5
Ulcerative Colitis (UC) 1.4 2.6 9.5 0.5 0.7 -0.1 0.0 1.3 1.3 -1.1 -3.1 3.0
Major Depression (MDD) 0.6 0.7 2.4 1.2 0.6 0.6 0.3 1.1 1.5 0.5 0.1 0.5
Reaction Time 0.1 0.3 1.0 -0.2 -0.2 1.0 0.3 0.8 0.3 0.2 0.4 -0.5
Verbal and Numeric Reasoning (VNR) 1.4 3.5 11.3 -3.0 -1.2 -3.4 -1.5 -1.8 0.4 -1.0 -1.4 -0.8
Breast Cancer 2.0 4.8 12.7 -2.7 -1.1 0.1 -0.6 -2.4 -3.6 -0.0 1.7 -3.5
Ovarian Cancer 0.7 0.9 3.3 0.1 1.1 0.7 0.9 -1.8 -0.4 1.1 0.5 -1.0
Prostate Cancer 0.4 0.6 2.3 -0.5 -0.8 -0.9 -0.5 -0.4 -0.3 -1.5 -0.3 0.9
Age at First Birth 0.5 0.8 2.0 -1.2 -0.5 -1.4 -0.6 -1.2 -0.4 0.2 -0.9 -0.8
Bipolar Disorder (2011) 0.5 0.5 1.4 0.8 0.7 0.1 0.7 -0.7 0.6 1.2 0.3 -0.5
Body Mass Index (BMI) (2010) 0.3 0.5 1.3 0.4 -0.2 1.0 0.1 1.1 -0.3 0.4 1.1 -0.5
Coronary Artery Disease (CAD) 1.1 1.3 3.4 -0.7 -1.3 -0.1 -1.6 1.4 -1.1 -1.8 -0.3 0.7
Crohns Disease (2012) 1.3 2.0 5.1 1.3 1.9 0.4 1.6 -0.6 2.1 2.3 -0.6 0.2
Mean Putamen Volume 0.4 0.4 2.0 0.5 0.1 0.2 -0.4 -1.1 -0.2 0.2 -0.3 -1.4
Fasting Glucose 0.6 0.7 4.4 0.4 0.7 0.5 0.9 -2.1 -0.0 0.1 0.2 0.2
HbA1C 1.5 1.7 4.4 -1.0 -1.7 -1.7 -2.1 0.7 -0.8 -1.3 -0.2 -1.2
HDL Cholesterol 1.3 2.1 4.0 1.7 2.0 1.5 1.5 1.7 1.3 1.5 0.7 0.3
LDL Cholesterol 0.3 0.5 2.9 0.4 0.3 -0.4 0.1 -0.3 -0.1 -0.4 -1.7 1.1
Lupus 0.5 0.8 3.3 0.2 1.1 0.2 0.2 1.3 -0.5 -0.4 -1.8 0.4
Neuroticism (2016) 0.6 0.8 3.3 0.4 0.1 0.1 -0.2 0.8 1.8 -0.4 -1.6 0.7
Primary Biliary Cirrhosis 1.4 2.0 4.4 0.3 2.1 0.4 1.6 -1.8 2.0 1.2 -1.3 -0.1
Rheumatoid Arthritis 0.9 1.3 4.3 -0.4 0.0 1.4 -0.6 2.1 -1.1 -1.7 0.6 0.3
Schizophrenia (2014) 4.3 9.5 21.7 3.9 3.6 2.8 3.8 -1.7 4.7 2.8 0.3 1.5
Triglycerides 0.3 0.5 1.4 -0.5 0.5 1.0 0.9 -1.2 -0.3 0.2 -0.4 0.7
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.4 0.9 -0.2 0.5 -0.4 0.6 -0.2 -1.2 -0.5 0.5
Ulcerative Colitis 0.7 1.0 2.0 0.7 1.4 1.1 1.0 0.1 1.3 0.1 -1.2 1.1
Blood Eosinophil Count 1.7 13.0 26.4 -4.2 -3.6 -1.7 -4.6 0.1 -4.8 -5.1 -3.2 1.0
Blood Platelet Count 0.1 0.9 2.3 1.2 0.4 1.4 0.4 0.4 0.8 1.5 1.1 -0.7
Blood Red Count 0.3 3.1 14.2 -1.3 -1.0 -1.2 -1.1 -3.8 -1.7 0.0 -1.2 -2.1
Blood White Count 0.7 5.0 22.7 1.1 0.2 -1.0 0.9 -4.8 1.7 2.0 -3.0 1.9
Heel T-Score 6.7 53.0 100.0 -6.6 -10.0 -9.5 -9.5 -2.9 -7.2 -6.6 -6.9 -1.9
BMI 0.7 3.9 19.7 -1.0 -0.5 0.2 -1.1 4.4 -0.2 -1.8 -2.9 1.2
Height 0.3 6.0 28.9 0.4 0.5 0.1 1.0 -1.8 -1.2 2.3 3.7 -5.4
Waist Hip Ratio (WHR) 0.7 3.1 7.5 -1.6 -2.7 -1.0 -2.4 -0.1 -2.1 -2.5 0.6 -0.3
Systolic Blood Pressure 1.2 6.0 18.3 -3.0 -1.8 -2.4 -2.2 -0.7 -0.0 -2.9 -4.3 2.1
Smoking Status 0.8 2.0 8.5 1.1 1.5 0.6 1.4 0.5 1.9 2.9 -0.4 0.1
Allergy or Eczema 2.2 5.7 17.6 -1.2 -1.2 0.4 -1.6 -0.7 -3.4 0.0 4.2 -4.0
Cardiovascular Disease 1.5 4.8 14.2 -2.0 -1.7 -1.5 -2.2 1.7 0.3 -2.4 -3.8 2.5
Hypothyroidism (self reported) 0.9 2.0 5.8 -0.1 0.9 -0.4 0.8 -0.1 2.4 -0.8 -2.1 2.3
Respiratory disease 0.1 0.2 0.6 -0.2 0.2 0.2 -0.3 -0.3 -0.6 -0.4 0.8 0.0
Type 2 Diabetes (T2D) (2018) 2.0 3.8 9.9 -1.1 -2.0 -2.3 -1.7 0.4 -0.6 -2.5 -3.1 2.1
Lung FEV1/FVC ratio 0.3 1.8 7.3 0.0 -0.2 -0.1 0.9 -1.6 -0.1 1.3 2.7 -1.8
Lung FVC 0.5 2.3 7.6 1.2 1.5 0.4 1.5 1.3 2.8 1.7 -0.7 1.4
Neuroticism 0.1 0.3 1.5 0.3 0.6 -0.0 0.2 0.3 1.2 0.3 0.1 -0.4
Chronotype (morning person) 1.1 2.6 13.2 -2.3 -1.0 -0.4 -0.8 -0.6 -1.5 -3.6 -0.7 0.4
Hair Pigment 0.0 0.8 3.1 0.6 -1.8 -0.3 -1.0 -0.8 -0.1 -1.2 -0.4 0.7
Tanning 0.7 8.3 15.4 -3.4 -2.5 -3.4 -2.4 -2.0 -2.6 -3.7 -3.9 0.1
Hand grip strength (left) 0.6 1.7 7.5 -2.7 -0.5 -0.2 -0.6 -0.1 -1.5 -1.7 -1.2 0.6
Number of treatments/medications taken 0.7 1.2 4.0 -0.8 -0.5 -0.8 -0.7 0.9 -0.3 -0.8 -1.9 2.0
Average weekly spirits intake 1.1 1.4 4.2 2.1 0.7 1.3 0.9 1.2 0.2 1.3 1.4 -0.8
Sensitivity / hurt feelings 0.5 0.8 3.4 0.1 0.8 1.0 0.2 0.4 -0.1 0.8 1.3 -1.8
Frequency of depressed mood in last 2 weeks 1.1 1.6 8.7 -0.3 -0.1 -0.8 -1.0 2.9 1.6 0.9 -0.2 -0.5
Hearing difficulty/problems: Yes 0.2 0.3 1.1 -0.5 -0.5 -0.5 -0.6 -0.8 -0.4 -0.1 -0.1 -1.1
Relative age of first facial hair 0.5 1.0 4.5 0.3 -0.2 -1.0 -0.0 -2.1 -0.0 0.1 1.0 -1.5
Other serious medical condition/disability diagnosed by doctor 0.8 1.1 4.6 0.8 -0.3 0.2 -0.2 0.7 0.9 -0.4 -1.7 2.2
Ever used hormone-replacement therapy (HRT) 3.4 4.3 10.2 1.9 1.7 2.9 1.7 1.9 1.7 1.9 3.2 -0.8
Ever had hysterectomy (womb removed) 0.6 0.7 3.7 0.2 -0.2 -0.1 -0.2 0.6 0.5 -1.1 -0.8 1.9
Systolic blood pressure, automated reading 1.9 5.6 14.2 -2.0 -2.3 -2.9 -2.5 -0.7 -0.9 -2.9 -3.8 1.4
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 1.0 -0.2 -0.5 -0.8 -0.9 0.2 -0.7 -1.0 -0.8 -0.3
Angina 2.6 3.4 9.3 -1.9 -3.1 -1.7 -2.7 0.5 -2.0 -1.7 -0.4 -0.4
Medication for hormone replacement therapy 1.4 1.5 8.1 1.7 -0.2 0.9 0.3 0.4 0.0 0.7 2.8 -1.3
Vitamin and mineral supplements 3.4 4.6 8.7 -1.1 -2.7 -2.3 -3.0 1.1 -1.8 -2.7 -2.2 1.4
Supplements: Zinc 0.5 0.5 1.4 -0.4 0.5 0.1 0.7 -1.2 0.5 0.5 -1.0 0.7
Medication: Co-codamol 0.9 1.1 4.5 0.5 0.1 0.9 -0.1 1.4 0.4 -1.1 -0.9 2.1
Medication: Metformin 0.7 1.0 3.3 0.4 -0.6 -1.2 -0.6 1.0 0.4 -0.6 -1.8 1.2
Diabetes (father) 0.3 0.3 1.2 0.6 0.3 0.1 0.5 0.3 0.2 -0.3 -0.8 1.1
Diabetes (mother) 1.5 1.9 7.3 -0.4 -0.6 -1.5 -0.9 -0.6 0.3 -2.3 -2.7 0.7
Severe depression (siblings) 0.8 0.9 3.1 1.2 0.1 0.1 0.1 1.7 1.2 0.3 -0.3 1.5
Pack years adult smoking proportion 0.4 0.6 1.5 1.2 0.6 0.6 0.4 1.0 0.7 0.9 0.2 0.5
Impedance of leg (right) 0.8 3.8 27.1 -1.3 0.8 -0.5 0.9 -5.2 -0.8 0.7 0.4 -1.5
Leg fat-free mass (left) 0.4 2.2 18.1 0.1 -0.1 0.4 -0.6 4.3 0.0 -0.8 -0.3 -0.7
Trunk fat percentage 0.5 1.8 4.6 1.2 2.1 0.1 1.6 0.4 2.1 1.5 -1.2 0.1
Hand grip strength (right) 1.9 5.2 17.1 -4.1 -2.2 -1.1 -2.1 1.1 -2.8 -2.6 -1.6 0.8
Townsend deprivation index at recruitment 1.5 2.1 5.0 0.9 1.6 2.2 1.6 1.3 1.7 1.0 0.2 1.4
Current tobacco smoking 1.6 2.5 6.7 0.8 2.3 0.8 2.1 -0.6 1.9 2.6 1.0 -0.5
Average weekly fortified wine intake 1.1 1.3 2.9 -0.7 -1.5 -1.7 -1.3 -0.7 -1.5 -0.4 0.0 -1.4
Maternal smoking around birth 0.2 0.3 0.6 -0.7 -0.1 -0.6 -0.4 -0.5 -0.6 -0.2 -0.6 -0.4
Fed-up feelings 0.2 0.4 1.1 -0.4 -0.9 -0.3 -0.8 0.7 0.1 -0.2 0.7 -1.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 5.3 -0.4 -0.4 -0.3 -1.2 2.3 0.6 -0.6 -0.9 -0.1
Relative age voice broke 1.2 1.8 5.0 -1.1 -1.6 -2.2 -1.2 -2.0 -0.5 -0.7 -0.3 -0.9
Taking other prescription medications 1.2 1.9 9.5 0.9 0.0 -0.2 0.0 0.8 1.4 -1.0 -1.8 3.1
Age when periods started (menarche) 0.9 2.2 5.4 -1.4 -2.1 -1.9 -1.6 -2.3 -0.7 -0.3 -1.2 0.2
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 1.9 -0.3 -0.5 -0.6 -0.6 0.6 0.0 -0.1 1.4 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 6.4 14.6 28.3 -3.8 -5.3 -4.6 -5.1 -0.4 -4.2 -3.8 -2.4 -1.7
Tinnitus: Yes, but not now, but have in the past 0.6 0.6 1.5 1.2 -0.1 0.3 -0.2 1.1 0.5 1.0 1.2 0.2
Qualifications: CSEs or equivalent 0.4 0.5 3.2 -0.9 -0.0 0.6 -0.1 1.8 -0.4 -0.5 -0.3 0.1
Serious illness, injury or assault to yourself 0.4 0.4 2.7 0.1 0.3 -0.2 -0.2 1.6 0.0 -0.4 -0.8 0.5
High blood pressure 0.6 1.8 3.9 -1.8 -1.4 -1.1 -1.7 0.8 -0.0 -1.1 -2.0 0.7
Hayfever, allergic rhinitis or eczema 2.8 6.2 17.2 -1.8 -1.2 -0.3 -1.5 -1.4 -3.6 0.2 4.0 -4.2
Multivitamins +/- minerals 4.9 6.2 10.7 2.2 2.8 3.0 3.3 -1.0 2.0 3.2 2.6 -1.1
Stomach or abdominal pain in last month 0.3 0.3 1.4 -1.2 -0.2 0.0 -0.4 1.0 -0.2 -0.4 0.4 -0.3
Supplements: Glucosamine 0.3 0.4 2.1 -0.7 0.3 0.5 0.2 -0.1 -0.2 -0.2 0.7 -1.4
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 1.1 0.4 -1.1 -0.4 -1.0 1.0 -1.0 -0.5 -0.2 0.2
Medication: Atenolol 0.2 0.3 0.7 0.1 -0.3 -0.4 -0.8 -0.1 -0.8 0.2 -0.8 0.1
Medication: Levothyroxine sodium 1.3 2.1 6.3 0.4 0.3 -0.5 0.1 0.5 2.4 -1.3 -2.2 2.5
Sitting height 0.2 1.3 8.6 -1.1 0.6 0.5 0.1 0.3 -0.5 0.1 0.8 -2.9
Chronic bronchitis/emphysema (father) 0.6 0.7 2.1 -0.1 0.5 -0.5 -0.2 -0.4 1.1 -0.6 -1.3 1.5
High blood pressure (mother) 1.1 1.6 2.5 -1.4 -1.6 -1.2 -1.4 -1.1 -1.3 -1.4 -1.3 0.0
Body mass index (BMI) 0.7 2.9 15.2 0.2 0.2 0.0 -0.4 3.9 1.0 -1.2 -2.3 1.6
Impedance of leg (left) 0.6 2.7 19.6 -1.4 0.4 -0.9 0.5 -4.4 -0.5 0.3 -0.1 -1.0
Leg predicted mass (left) 0.4 2.2 18.1 0.1 -0.0 0.5 -0.5 4.2 0.0 -0.8 -0.3 -0.7
Trunk fat mass 0.2 1.0 2.8 0.4 1.3 -0.0 0.7 1.7 1.2 0.6 -1.2 -0.2
Waist circumference 0.3 1.2 9.4 0.3 0.2 0.5 -0.4 3.1 0.3 -0.7 -0.3 -0.3
Number of incorrect matches in round 0.8 1.4 4.5 1.5 0.5 0.8 1.0 -1.4 0.4 2.1 1.4 -0.1
Past tobacco smoking 0.4 0.6 1.5 0.0 -0.7 -1.0 -0.7 -1.0 -1.2 -1.2 0.0 0.1
Alcohol usually taken with meals 2.1 3.4 10.1 -1.1 -0.6 0.9 -0.4 -1.1 -2.3 1.7 2.9 -3.2
Nervous feelings 0.4 0.7 2.6 -0.0 -0.3 0.7 -0.5 0.6 -1.3 -0.6 0.8 -1.6
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 12.0 0.4 0.3 0.8 -0.5 3.5 0.5 0.7 0.1 -0.3
Hearing difficulty/problems with background noise 0.1 0.1 0.5 -0.2 -0.4 -0.5 -0.4 -0.1 0.3 0.3 0.1 -0.7
Hair/balding pattern: Pattern 2 0.7 0.9 2.0 -0.5 -1.2 -0.3 -1.2 1.4 0.0 -0.2 1.3 -1.1
Had menopause 0.2 0.2 1.3 -0.1 -0.1 -0.3 -0.3 0.1 -0.7 0.1 0.3 -1.1
Had other major operations 1.0 1.3 3.7 1.3 0.6 1.3 0.6 1.9 1.5 0.3 0.9 0.7
Forced vital capacity (FVC) 0.1 0.3 1.0 -0.2 -0.2 -0.2 -0.1 0.9 0.1 1.0 0.2 -0.8
Heel bone mineral density (BMD) T-score, automated (right) 9.1 20.8 41.1 -4.5 -6.4 -5.6 -6.3 0.2 -4.3 -4.9 -3.1 -1.3
Ever unenthusiastic/disinterested for a whole week 1.4 1.7 6.0 0.8 1.1 0.9 1.4 -0.1 2.5 1.9 1.1 -0.4
Qualifications: None of the above 0.3 0.7 3.2 0.3 -0.7 0.1 -0.7 1.0 -0.4 -1.8 -0.2 0.8
Financial difficulties in last 2 years 0.3 0.4 1.1 0.3 1.0 0.3 1.0 -0.4 0.9 0.0 -0.5 0.4
Mouth/teeth dental problems 0.5 0.7 3.3 0.6 0.4 1.2 0.7 -0.4 -0.1 0.7 1.8 -0.2
Heart attack 1.8 2.3 3.8 -1.0 -1.7 -1.9 -2.0 -0.0 -1.7 -1.8 -1.5 -0.7
Allergy 1.7 3.9 9.7 1.6 1.0 0.6 1.4 0.5 3.1 0.4 -3.1 3.1
Pain all over the body in last month 1.0 1.1 4.2 1.3 0.1 -0.0 0.2 -0.1 -0.3 -1.2 -1.5 2.0
Diabetes (self-reported) 2.6 4.1 11.5 -1.1 -1.9 -2.3 -2.1 1.2 -1.1 -2.4 -3.4 1.4
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 2.6 -0.8 -0.7 -0.6 -1.1 -0.5 -1.3 -0.3 1.4 -1.6
Medication: Ramipril 1.0 1.3 3.1 -0.6 -1.7 -0.5 -1.8 1.1 -0.9 -1.5 -0.9 0.6
Medication: Simvastatin 1.8 2.6 6.2 -0.6 -1.6 -1.1 -1.6 2.1 -0.3 -1.6 -2.5 1.9
Fluid intelligence score 2.0 4.3 10.7 -3.2 -2.0 -3.3 -1.9 -1.5 -0.8 -1.8 -1.7 -0.5
Illnesses of siblings 2.9 4.1 9.5 1.7 2.1 1.6 2.3 -1.2 0.6 3.1 3.0 -1.4
Neuroticism score 0.2 0.3 1.3 0.3 0.5 0.0 -0.0 0.6 1.1 0.5 0.4 -0.7
Weight 0.3 1.7 12.5 -0.4 -0.1 -0.1 -0.7 3.5 -0.1 -1.0 -1.0 -0.5
Impedance of arm (right) 3.5 16.2 44.0 2.4 4.0 2.0 4.4 -6.6 1.8 5.2 3.9 -3.4
Arm fat percentage (right) 0.5 1.8 4.4 1.2 1.9 0.4 1.4 1.2 2.1 1.0 -1.4 0.6
Trunk fat-free mass 1.1 6.1 19.4 -2.3 -2.4 -0.9 -2.8 4.4 -2.2 -2.9 -0.8 -1.3
Hip circumference 0.7 3.2 7.3 1.8 2.7 1.9 2.1 1.7 1.7 1.7 0.3 -1.1
Time employed in main current job 2.0 2.3 5.8 -0.3 -0.7 -0.4 -0.8 2.3 -0.7 -1.7 -2.4 2.2
Alcohol intake versus 10 years previously 0.5 0.8 2.6 0.6 0.9 0.7 1.1 0.1 0.9 0.5 -0.9 1.6
Father’s age at death 0.8 1.0 3.5 -0.2 -0.8 -1.1 -0.5 -1.9 -0.4 1.1 0.4 -1.5
Worrier / anxious feelings 0.2 0.4 1.7 0.5 0.8 0.8 0.4 0.5 0.2 0.6 1.3 -0.2
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.2 3.6 1.0 0.7 0.2 0.5 1.9 1.4 -0.3 -0.3 1.9
Falls in the last year 0.8 1.0 4.6 2.1 -0.3 1.5 0.1 0.6 0.8 0.9 0.7 -0.5
Hair/balding pattern: Pattern 3 0.8 1.2 2.4 1.5 1.3 1.3 1.6 0.2 0.9 1.3 0.1 0.8
Number of live births 0.3 0.4 0.9 -0.9 -0.2 -0.9 -0.3 0.0 0.6 0.6 0.1 -0.8
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 1.8 -0.1 -0.0 0.3 0.2 1.4 0.5 1.3 1.2 -1.1
Pulse rate 0.7 1.1 6.3 1.0 0.2 0.3 -0.5 2.5 -0.1 -1.2 -0.2 0.9
Happiness 0.2 0.3 0.6 0.5 -0.5 -0.8 -0.5 0.0 0.8 0.3 -0.8 -0.0
Noisy workplace 0.4 0.5 1.0 0.2 0.6 0.3 0.5 1.0 1.0 -0.3 -1.0 0.9
Qualifications: A levels/AS levels or equivalent 0.3 0.7 2.0 -1.3 -0.6 -1.1 -0.3 -1.4 0.0 0.1 0.2 -0.7
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 0.8 -0.0 -0.8 -0.3 -0.7 0.5 -0.9 -0.5 0.4 -0.1
Mouth/teeth dental problems: Dentures 0.6 1.1 4.4 -1.5 -0.0 -0.7 -0.7 0.7 -0.1 -1.0 -2.1 -0.5
Asthma 0.6 1.2 2.9 -1.7 -0.8 -1.1 -1.3 -0.1 -1.4 -1.7 -0.0 0.0
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 4.7 -0.8 -0.2 -1.0 -0.3 -0.2 -0.1 -1.4 -2.2 1.1
Medication: Cholesterol lowering 4.3 6.6 13.4 -1.5 -2.9 -1.8 -2.9 1.6 -2.1 -3.5 -3.7 2.2
Depression (self-reported) 3.4 4.0 8.7 2.1 2.3 2.3 1.7 2.1 3.0 1.9 0.3 1.2
Medication: Lansoprazole 0.5 0.6 2.1 1.1 0.1 0.1 0.5 -0.2 0.8 1.4 0.9 -0.5
Prospective memory result 0.4 0.5 1.6 -0.5 -0.7 0.0 -0.5 -1.3 -1.2 -0.4 0.6 -0.4
Lung cancer (father) 1.8 2.1 5.0 1.9 1.2 1.8 1.3 1.2 1.6 0.2 -0.4 2.2
Illnesses of mother 3.2 3.9 8.4 1.3 2.4 2.1 2.3 -0.5 1.5 2.6 2.9 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 2.0 0.4 0.9 0.7 1.1 0.8 1.1 1.4 0.8 -0.7
Pulse wave Arterial Stiffness index 0.6 0.7 1.5 -0.8 1.0 0.8 0.8 -1.2 -0.9 -0.5 0.4 -1.0
Impedance of arm (left) 3.5 16.3 33.5 3.0 4.3 2.3 4.7 -5.8 2.3 5.4 4.0 -2.9
Arm fat mass (right) 0.3 1.2 5.4 0.4 0.8 -0.1 0.2 2.3 1.1 -0.2 -1.7 0.3
Trunk predicted mass 1.1 6.2 20.0 -2.3 -2.4 -0.9 -2.8 4.5 -2.3 -2.9 -0.7 -1.3
Standing height 0.4 3.7 19.9 -1.6 -0.6 -0.5 -0.7 -0.4 -2.1 0.3 2.3 -4.5
Length of working week for main job 0.6 0.7 2.0 0.2 -1.0 -0.2 -0.9 1.4 -0.4 -0.5 -0.4 1.3
Exposure to tobacco smoke at home 0.9 1.0 2.6 1.3 1.0 1.6 1.1 0.6 0.7 0.3 1.3 0.1
Breastfed as a baby 0.1 0.2 0.6 -0.2 0.4 0.1 0.5 0.3 0.8 0.3 0.5 0.3
Tense / ‘highly strung’ 0.6 1.0 4.5 0.2 1.3 0.3 0.6 1.2 2.1 0.6 -0.9 0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 1.5 2.3 5.2 1.0 2.3 1.7 1.5 2.2 1.6 1.2 0.7 0.5
Hair/balding pattern: Pattern 4 0.4 0.9 2.9 0.3 0.9 -0.5 0.3 0.0 1.4 -0.8 -1.7 1.3
Birth weight of first child 0.3 0.6 1.4 0.8 0.1 -0.7 -0.1 1.2 1.2 0.3 -0.4 1.2
Peak expiratory flow (PEF) 0.5 1.0 3.5 -0.9 -0.5 -0.3 -0.6 0.9 -0.0 0.6 1.8 -1.9
Pulse wave reflection index 0.6 0.8 3.3 -0.7 0.5 0.5 0.9 -1.8 -0.6 0.9 0.5 -0.9
Ever highly irritable/argumentative for 2 days 1.8 2.2 5.5 2.4 1.6 1.1 1.6 0.4 2.0 1.8 0.4 0.0
Loud music exposure frequency 0.3 0.3 1.6 0.0 -0.3 -0.2 -0.1 -0.5 0.2 1.0 0.1 -1.3
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 0.9 0.0 0.2 -0.9 0.2 -0.8 0.7 0.5 -0.7 0.2
Mouth/teeth dental problems: Bleeding gums 1.8 2.4 8.0 0.6 -0.6 -2.2 -0.8 -0.8 1.6 -0.8 -2.8 1.8
Blood clot in the leg (DVT) 0.8 1.0 4.7 -0.0 0.9 1.3 0.9 2.2 -0.8 -0.6 0.4 -0.5
Medication: Paracetamol 0.6 1.1 4.4 -0.2 0.5 -0.7 -0.0 0.6 0.4 -1.1 -2.1 1.6
Headache pain in last month 0.3 0.6 1.4 -0.3 0.9 1.2 1.0 0.8 0.4 0.6 -0.5 0.8
Medication for cholesterol, blood pressure or diabetes 2.2 3.6 12.2 0.5 1.3 0.8 1.5 -1.4 0.9 2.6 3.5 -2.4
Glaucoma (self-reported) 1.5 1.8 3.2 1.4 1.5 1.3 1.8 -0.8 0.4 1.8 1.6 -0.4
Gout (self-reported) 0.4 0.6 1.8 0.4 -0.5 -0.7 -0.5 -0.3 0.6 -0.6 -1.3 1.3
Hypothyroidism/myxoedema (self-reported) 0.7 1.4 5.2 0.3 0.6 -0.9 0.6 -0.5 2.3 -0.5 -1.6 1.7
Medication: Amlodipine 0.6 0.8 2.7 -1.6 -0.7 -1.1 -0.7 -0.2 0.7 -0.9 -1.0 0.2
Medication: Ventolin 100micrograms inhaler 1.7 2.2 3.9 -2.0 -1.4 -1.7 -1.6 -1.0 -1.6 -2.0 0.1 -1.1
Birth weight 0.4 1.0 2.1 0.8 1.4 0.9 1.5 0.5 1.0 1.2 0.3 0.1
Chronic bronchitis/emphysema (mother) 0.6 0.7 1.9 0.7 0.6 1.1 0.6 1.4 -0.2 -0.4 -0.8 1.2
High blood pressure (siblings) 0.8 1.2 2.8 -0.8 -1.5 -0.7 -1.7 0.0 0.1 -1.6 -1.4 0.1
Forced vital capacity (FVC), Best measure 0.1 0.2 0.9 -0.4 0.2 -0.2 0.3 0.3 0.4 0.9 -0.0 -0.8
Body fat percentage 0.3 1.4 4.1 0.6 1.5 -0.3 0.8 1.1 1.7 0.5 -2.0 0.7
Leg fat percentage (right) 0.5 1.7 7.9 -0.4 0.7 -0.4 -0.0 1.7 0.7 -1.1 -2.8 1.4
Arm fat-free mass (right) 1.3 6.5 28.9 -1.8 -2.1 -0.9 -2.7 5.4 -1.6 -2.9 -1.7 -0.1
Exposure to tobacco smoke outside home 0.5 0.7 1.9 1.4 0.1 0.4 0.6 -0.2 1.2 0.9 1.1 -0.2
Comparative body size at age 10 0.3 0.8 2.6 -0.5 0.1 0.4 -0.3 1.1 -1.1 -1.4 -1.6 -0.4
Number of full brothers 0.6 0.7 2.6 0.4 -0.5 1.1 -0.5 1.6 0.1 0.1 0.2 1.4
Worry too long after embarrassment 0.2 0.3 1.2 0.7 -0.0 0.2 0.1 0.4 0.3 0.9 1.1 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.6 2.1 9.0 0.4 1.2 0.4 0.5 3.0 1.8 0.7 -0.7 1.9
Wheeze or whistling in the chest in last year 0.3 0.5 1.0 -0.6 -0.7 0.4 -0.7 1.0 -0.9 -0.5 0.8 -0.2
Number of children fathered 0.8 1.0 4.0 -2.0 -0.6 -0.3 -0.7 1.4 -1.1 -0.8 0.1 -0.0
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.5 1.5 0.5 1.0 0.7 0.3 1.2 0.6 -0.2 -0.8 0.7
Age at first live birth 0.2 0.4 1.1 0.2 0.7 0.6 0.5 0.7 0.7 1.0 -0.2 0.5
Pulse wave peak to peak time 0.7 0.8 2.0 0.4 -1.4 -1.4 -1.2 0.9 0.5 0.4 -0.4 0.5
Health satisfaction 0.1 0.2 0.6 0.5 -0.8 -0.1 -0.7 0.2 -0.2 -0.5 0.1 -0.0
Shortness of breath walking on level ground 1.8 2.1 7.7 -0.1 0.2 0.1 -0.6 0.7 0.3 -2.8 -2.3 2.2
Qualifications: College or University degree 0.6 1.8 7.4 0.2 0.5 -0.6 0.5 -2.7 0.5 1.9 1.2 -1.5
Eye problems/disorders: None of the above 0.1 0.2 0.5 0.1 0.7 0.6 0.7 -0.1 -0.1 0.0 0.2 0.1
Mouth/teeth dental problems: Loose teeth 0.4 0.4 1.8 0.2 0.7 -0.0 0.4 -0.0 -0.1 1.3 0.3 -1.1
Emphysema/chronic bronchitis 0.8 0.9 3.5 0.8 1.1 0.9 0.4 1.9 0.7 -0.8 -0.6 0.9
Medication for pain relief, constipation, heartburn 0.6 1.0 5.2 -0.0 -0.2 0.7 0.2 -0.7 -0.4 0.5 2.3 -1.5
Neck or shoulder pain in last month 0.5 0.7 2.9 -0.5 -0.6 -0.5 -0.6 1.7 -0.3 -0.6 -1.3 -0.2
Medication: Blood pressure 0.6 1.1 3.2 -0.1 -0.6 -0.6 -1.0 1.8 -0.3 -0.7 -1.8 1.2
Angina (self-reported) 3.0 3.9 10.5 -2.1 -3.2 -1.8 -2.9 0.3 -2.3 -1.8 -0.4 -0.6
Migraine (self-reported) 0.4 0.4 1.2 -0.7 0.8 0.8 1.1 0.1 0.8 0.2 -0.3 0.7
Medication: Ibuprofen 0.4 0.5 2.6 -0.4 0.0 -0.2 0.2 -0.1 -0.1 -0.8 -1.6 0.7
Medication: Allopurinol 0.4 0.5 1.4 0.6 -0.7 -0.4 -0.5 -1.2 -0.0 -0.9 -0.9 0.5
Medication: Omeprazole 0.6 0.7 2.1 0.5 0.9 1.4 0.9 0.8 0.7 0.1 1.3 0.0
Medication: Seretide 50 evohaler 1.2 1.4 2.7 -0.9 -0.8 -1.4 -1.5 1.3 0.5 -1.4 -1.6 0.8
Mean time to correctly identify matches 0.2 0.3 0.8 -0.0 -0.2 0.6 0.3 0.2 0.6 0.9 0.6 -0.8
Heart disease (mother) 1.4 1.7 7.4 -0.8 -0.6 -1.5 -0.7 -0.1 -0.2 -1.4 -2.7 1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.2 0.4 -0.2 -0.5 -0.3 -0.5 -0.5 -0.6 0.4 -0.5 0.5
Whole body fat mass 0.3 1.3 5.8 0.1 0.7 -0.3 0.1 2.4 0.9 -0.4 -2.0 0.4
Leg fat mass (right) 0.6 2.3 10.6 -0.3 0.3 -0.3 -0.4 3.3 0.6 -1.3 -2.5 1.0
Arm predicted mass (right) 1.3 6.4 25.0 -1.9 -2.1 -1.1 -2.7 5.0 -1.7 -3.1 -1.9 -0.2
Pulse rate, automated reading 0.1 0.2 1.0 0.7 0.1 0.0 -0.2 0.7 -0.1 -1.0 -0.3 0.0
Alcohol intake frequency. 0.1 0.3 1.2 0.1 0.0 0.1 -0.6 1.1 -0.3 -1.0 -0.2 -0.0
Comparative height size at age 10 0.6 3.2 14.6 -0.7 0.4 0.9 0.1 1.0 -1.2 1.9 2.6 -3.8
Number of full sisters 1.4 1.7 3.3 1.4 1.4 1.4 1.4 0.9 1.8 0.2 -0.8 1.7
Suffer from ‘nerves’ 0.4 0.7 1.3 0.3 1.1 1.1 0.8 1.1 0.7 -0.2 -0.9 0.3
Overall health rating 0.5 1.1 3.7 0.5 0.9 0.7 0.7 1.9 1.4 -0.4 0.0 1.4
Chest pain or discomfort 1.4 2.1 4.4 0.6 1.8 1.7 1.7 1.7 1.6 -0.0 -0.0 2.1
Had major operations 0.7 0.8 2.1 1.5 -0.7 0.7 -0.5 1.3 0.3 -0.4 -0.2 1.3
Age at last live birth 0.7 1.0 3.5 -1.0 0.1 -0.9 -0.1 -0.5 0.3 1.5 1.0 -1.9
Family relationship satisfaction 0.3 0.4 1.7 0.7 -0.1 -0.4 -0.2 -0.3 0.3 0.2 -1.1 1.3
Leg pain on walking 0.1 0.2 0.8 0.4 0.5 0.2 0.1 -0.0 0.9 -0.1 0.0 -0.6
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.8 3.0 -0.9 -0.5 -1.2 -0.1 -1.7 0.2 0.2 -0.5 -1.0
Commuting to job workplace: Car/motor vehicle 1.0 1.1 7.3 -0.7 -0.8 0.0 -1.0 2.7 -0.5 -0.7 0.1 -0.0
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.5 -0.3 0.3 0.2 0.4 -0.1 0.7 0.7 -0.4 0.5
Medication: Aspirin 1.2 1.6 4.6 -0.8 -1.4 -1.2 -1.3 0.8 -1.6 -0.6 -2.1 1.0
Supplements: Vitamin C 2.8 3.3 8.8 0.5 1.0 0.6 1.6 -2.5 1.0 3.0 1.8 -2.5
Knee pain experienced in last month 0.6 0.9 1.8 1.4 1.0 -0.5 1.2 -0.9 0.9 0.3 -1.0 0.9
Hypertension (Self-reported) 0.9 2.6 5.7 -2.1 -1.8 -1.5 -2.1 0.8 -0.0 -1.4 -2.4 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.3 1.5 3.3 1.5 1.3 1.8 1.5 0.6 0.5 1.3 1.2 0.1
Illnesses of father: Heart disease 0.4 0.6 2.8 -0.6 -0.5 -0.5 -0.2 -1.7 -0.3 -0.5 -1.2 0.4
Illnesses of siblings: Diabetes 5.4 6.7 11.1 -2.6 -3.0 -2.8 -3.3 1.4 -2.1 -3.1 -3.0 1.0
Smoking status: Previous 0.1 0.1 0.5 -0.2 -0.1 0.7 0.1 0.4 0.1 0.5 -0.3 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.3 1.1 -0.6 0.5 -0.0 0.4 -0.5 -0.3 -0.9 -1.0 0.2
Whole body fat-free mass 0.8 4.5 22.0 -1.5 -1.7 -0.6 -2.1 4.7 -1.4 -2.3 -0.9 -0.9
Leg fat-free mass (right) 0.5 2.6 21.3 0.0 -0.3 0.3 -0.8 4.6 0.1 -0.9 -0.4 -0.5
Arm fat percentage (left) 0.6 2.3 5.0 1.5 2.1 0.7 1.6 1.5 2.2 1.1 -1.3 0.8
Average weekly red wine intake 0.9 1.4 3.7 -0.2 1.9 1.9 1.7 0.4 0.2 1.4 0.1 -0.4
Handedness (chirality/laterality): Left-handed 0.9 1.1 2.6 1.6 0.8 1.5 1.0 0.4 0.9 1.1 1.0 0.1
Mood swings 1.1 2.1 5.7 1.3 1.6 0.8 0.8 2.1 2.4 0.6 -1.2 1.0
Loneliness, isolation 0.2 0.3 1.2 -0.1 0.3 -0.2 -0.3 0.8 0.7 0.4 -0.0 -1.1
Long-standing illness, disability or infirmity 0.9 1.4 5.7 0.5 -0.4 -0.3 -0.4 1.1 0.5 -1.6 -1.4 2.4
Ever had bowel cancer screening 0.8 0.9 2.8 0.8 0.9 0.6 0.9 0.6 0.4 -0.0 -1.6 1.7
Diabetes diagnosed by doctor 2.4 3.9 9.0 -0.8 -1.9 -2.4 -2.2 1.7 -0.6 -2.3 -3.0 1.7
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.4 -0.4 0.4 -0.5 0.1 0.6 1.2 -0.2 -0.3 -0.1
Friendships satisfaction 1.2 1.4 6.2 0.8 -0.4 -0.9 -0.6 0.3 0.4 -1.2 -2.5 1.8
Qualifications: nursing, teaching 0.2 0.2 1.1 -0.2 0.4 -0.0 0.4 -0.5 1.0 0.4 0.5 0.2
Commuting to job workplace: Walk 0.5 0.5 1.9 0.6 0.5 0.9 0.8 -1.4 0.5 0.2 0.6 0.6
Eye problems/disorders: Cataract 0.3 0.3 0.8 -0.4 -0.7 -0.5 -0.9 0.5 0.5 -0.5 -0.4 -0.1
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 3.4 -0.1 -0.6 -0.3 -0.4 1.8 -0.3 0.3 -0.3 0.4
Medication for cholesterol 0.1 0.2 0.4 0.2 0.6 0.2 0.4 -0.7 0.2 0.6 -0.0 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.5 1.7 5.0 2.2 0.6 0.8 0.7 -1.0 0.5 2.0 1.8 -0.7
Back pain experienced in last month 0.3 0.4 1.1 1.0 0.4 0.8 0.2 0.2 0.6 0.3 0.8 -0.8
Mineral and other dietary supplements 0.8 1.1 4.0 0.2 -2.0 -1.5 -1.8 -0.1 -0.2 -0.6 -0.3 0.2
Breast cancer (self-reported) 0.6 0.8 2.3 0.4 0.7 -0.4 0.4 1.4 0.9 -0.2 -1.0 1.5
Asthma (self-reported) 0.6 1.3 3.5 -1.9 -0.8 -1.3 -1.3 -0.4 -1.1 -1.7 -0.2 -0.1
Osteoporosis (self-reported) 0.4 0.5 1.9 0.9 -0.4 0.4 -0.5 0.3 -0.0 0.8 1.4 -0.9
Osteoarthritis (self-reported) 0.2 0.2 0.8 0.9 0.4 -0.1 0.0 0.4 0.8 -0.1 -0.2 0.6
Medication: Aspirin 2.1 2.7 4.8 -1.0 -2.1 -1.6 -2.0 1.2 -2.0 -0.9 -2.2 1.0
Medication: Gliclazide 1.8 2.0 6.5 1.3 0.8 -0.4 0.8 0.3 1.9 -0.3 -2.2 2.5
Illnesses of father: None of the above (group 1) 0.6 0.7 3.3 0.6 0.0 0.9 0.1 0.4 0.2 0.8 1.8 -1.1
Smoking status: Current 2.1 3.3 7.7 1.2 2.5 1.3 2.3 -0.1 2.3 2.8 1.3 -0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.9 0.9 0.1 -0.2 0.4 -0.4 1.4 0.6 -0.2 0.4
Whole body water mass 0.8 4.4 21.8 -1.4 -1.6 -0.5 -2.1 4.7 -1.4 -2.3 -0.8 -0.9
Leg predicted mass (right) 0.5 2.6 21.1 0.0 -0.3 0.3 -0.8 4.6 0.1 -0.9 -0.3 -0.6
Arm fat mass (left) 0.4 1.5 7.2 0.6 0.9 0.0 0.3 2.7 1.3 -0.3 -1.7 0.5
Number of self-reported non-cancer illnesses 0.5 0.8 2.9 0.4 -0.1 -0.9 -0.4 0.6 1.4 -0.4 -0.9 1.7
Average weekly champagne plus white wine intake 0.2 0.3 0.7 -0.5 0.4 0.4 0.1 0.3 -0.6 0.1 0.8 -0.7
Miserableness 0.1 0.2 1.1 0.0 -0.4 -0.4 -0.5 1.0 0.2 -0.4 -0.1 -0.5
Guilty feelings 0.8 1.1 3.9 1.2 1.1 0.4 1.1 0.5 2.0 1.1 0.7 0.6
Wears glasses or contact lenses 1.3 1.5 5.8 0.5 -0.7 -0.1 -0.8 -0.6 -1.9 0.9 1.3 -2.4
Ever taken oral contraceptive pill 0.7 0.8 2.8 0.4 1.0 0.6 0.5 1.6 1.7 0.5 0.4 0.2
Hearing aid user 1.4 1.6 3.9 -1.4 -1.5 -0.9 -1.0 -1.2 -1.6 0.3 0.5 -2.0
Mother’s age at death 2.7 3.4 5.3 -2.0 -2.2 -2.0 -2.2 -1.6 -1.8 -0.6 0.8 -2.3
Financial situation satisfaction 0.3 0.4 1.2 0.5 -0.7 -0.2 -0.5 1.1 0.4 -0.0 -0.7 0.7
Tinnitus: Yes, now most or all of the time 0.7 0.8 2.7 -0.6 -0.7 -0.8 -0.2 -0.6 -1.3 -0.1 1.0 -1.6
Commuting to job workplace: Public transport 0.7 0.8 5.2 -0.8 -0.4 -0.9 0.0 -2.3 0.2 -0.2 -0.6 0.5
Eye problems/disorders: Glaucoma 0.3 0.4 1.1 0.3 0.7 0.7 0.8 -0.2 0.4 1.0 0.5 -0.3
Medication: Blood pressure 1.1 2.0 4.6 -1.8 -1.4 -1.3 -1.5 0.1 -0.7 -1.8 -2.1 1.0
Pain type(s) experienced in last month: Hip pain 0.4 0.6 1.1 -0.4 -1.1 -0.9 -0.8 -0.4 -0.9 0.1 -0.8 -0.7
Supplements: Fish oil (including cod liver oil) 0.5 0.6 1.9 -1.1 0.8 -0.3 0.8 -1.4 -0.5 -0.4 -0.9 0.1
High cholesterol (Self-reported) 2.9 5.2 13.2 -1.9 -2.6 -1.8 -2.4 0.8 -0.8 -2.9 -3.6 2.1
Medication: Bendroflumethiazide 0.2 0.3 0.9 -0.0 -0.1 0.2 -0.2 0.9 1.0 -0.3 -0.2 0.7
Medication: Paracetamol 0.6 0.9 4.1 0.1 -0.1 -0.7 -0.5 0.2 0.0 -1.1 -2.0 1.5
Medication: Lisinopril 0.2 0.3 0.6 -0.1 -0.4 -0.4 -0.7 0.4 -0.5 -0.6 -0.8 0.7
Medication: Atorvastatin 1.0 1.3 5.3 0.2 -0.5 0.8 -0.3 1.0 0.4 -1.4 -1.4 2.3
Illnesses of father: High blood pressure 0.3 0.4 1.0 -1.0 0.1 -0.4 -0.1 0.4 0.1 -1.0 -0.6 -0.9
Alcohol drinker status: Never 0.4 0.5 1.1 -0.1 -0.3 0.6 -0.6 1.0 -0.7 -0.2 1.0 -1.0
Ever smoked 0.8 1.4 5.2 0.7 0.9 0.6 1.0 0.6 2.1 2.3 0.5 0.1
Basal metabolic rate 0.6 3.5 20.4 -1.1 -1.2 -0.3 -1.7 4.5 -0.9 -1.9 -0.9 -0.8
Leg fat percentage (left) 0.6 2.2 9.3 -0.5 0.5 -0.6 -0.2 2.3 0.8 -1.2 -3.0 1.6
Arm fat-free mass (left) 1.4 6.9 20.7 -2.5 -2.4 -1.4 -3.0 4.6 -2.0 -3.2 -1.9 -0.7
Number of operations (self-reported) 1.2 1.8 5.2 1.2 0.4 2.0 0.7 2.3 1.4 0.6 1.5 0.4
Average weekly beer plus cider intake 0.1 0.2 0.9 0.2 0.0 -0.6 0.6 -0.2 1.0 0.3 -0.1 0.0
Irritability 0.1 0.2 0.6 -0.0 -0.4 -0.5 -0.7 0.3 0.8 -0.0 -0.5 0.4
Risk taking 5.0 7.3 14.0 2.1 3.7 2.7 3.2 2.1 3.3 2.6 -0.8 2.7
Ever had prostate specific antigen (PSA) test 1.7 2.0 6.0 -0.6 -0.7 -1.1 -0.2 -2.5 -1.7 1.3 1.1 -2.0
Fractured/broken bones in last 5 years 1.7 2.2 7.9 0.6 1.2 0.8 1.4 -1.1 0.5 1.6 2.8 -1.8
Age started oral contraceptive pill 0.5 0.6 1.8 -0.7 -0.5 -0.8 -1.0 1.3 -0.5 -0.1 -0.3 -0.8
Diastolic blood pressure, automated reading 0.4 1.4 5.2 0.9 -0.2 -0.5 -0.4 1.1 0.2 -1.3 -2.3 1.8
Ever depressed for a whole week 1.3 1.6 4.0 1.2 2.0 0.5 1.7 -0.1 1.1 1.8 0.5 -1.0
Unable to work because of sickness or disability 1.8 2.3 5.1 2.2 1.6 2.2 1.4 0.8 1.6 0.7 0.9 1.3
Commuting to job workplace: Cycle 0.6 0.7 1.9 0.6 -0.7 -0.4 -0.3 -1.3 -0.8 0.4 0.9 -1.4
Myopia 0.3 0.4 0.8 0.2 -0.9 0.5 -0.8 0.0 -0.8 -0.4 0.7 -0.7
Vascular/heart problems diagnosed by doctor 0.7 1.8 4.5 1.5 1.4 1.0 1.7 -1.2 -0.2 1.0 2.1 -1.1
Cholesterol lowering medication 1.0 1.5 3.9 -0.9 -1.3 -1.1 -1.3 1.3 0.2 -1.3 -2.0 1.2
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.6 0.2 1.1 1.3 1.1 0.6 0.4 0.3 1.0 -0.0
Pain experienced in last month 0.1 0.2 0.8 -0.1 -0.4 -0.1 -0.2 -0.9 0.4 0.6 0.7 -0.3
Supplements: Calcium 2.2 2.4 4.3 1.1 1.7 1.6 1.8 -0.6 0.3 2.0 2.1 -1.7
Basal cell carcinoma (self-reported) 0.4 0.5 2.0 -0.1 0.9 0.9 0.5 1.4 0.6 0.3 -0.3 0.1
Heart attack/myocardial infarction (self-reported) 2.2 2.8 4.9 -1.0 -1.9 -2.1 -2.2 0.4 -1.9 -2.0 -1.8 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.8 1.1 5.6 0.0 0.8 1.2 0.8 2.4 -0.7 -0.6 0.3 -0.3
Heart disease (siblings) 0.7 0.9 2.3 -0.1 -1.5 -1.4 -1.0 -0.2 -0.4 -1.2 -0.8 0.4
Alcohol drinker status: Previous 2.2 2.5 4.8 -0.9 -1.0 -1.7 -1.7 1.3 -0.2 -2.1 -1.9 2.2
Pack years of smoking 0.4 0.5 1.5 1.2 0.4 0.5 0.2 1.1 0.6 0.9 0.3 0.5
Impedance of whole body 1.8 9.0 35.8 1.1 2.9 0.9 3.2 -6.0 1.2 3.6 2.4 -2.2
Leg fat mass (left) 0.7 2.6 11.8 -0.3 0.2 -0.4 -0.5 3.4 0.6 -1.5 -2.7 1.1
Arm predicted mass (left) 1.2 6.2 18.6 -2.3 -2.3 -1.3 -2.8 4.3 -2.0 -3.1 -1.7 -0.7