Best TWAS P=2.69e-13 · Best GWAS P=2.16e-14 conditioned to 0.000219
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CYP19A1 | 0.04 | 0 | blup | 209 | 0.01 | 0.023 | 6.9 | 7.3 | 2.7e-13 | 0.51 | 0.07 | 0.21 | TRUE |
| 2 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | GLDN | 0.24 | 0 | blup | 110 | 0.06 | 0.010 | 3.7 | -5.2 | 1.7e-07 | -0.15 | 0.03 | 0.15 | TRUE |