[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (right) : ← →

chr15:90,208,219-91,886,448

Best TWAS P=1.44e-08 · Best GWAS P=5.75e-09 conditioned to 0.118

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	ZNF774	0.22	0.24	enet	16	0.23	7.6e-13	-5.5	-5.3	1.1e-07	0.87	0.06	0.94	FALSE
2	GTEx	Esophagus Gastroesophageal Junction	ZNF774	0.16	0.16	lasso	2	0.11	7.8e-05	-5.6	-5.7	1.5e-08	0.96	0.02	0.95	FALSE
3	GTEx	Esophagus Muscularis	ZNF774	0.18	0.19	lasso	5	0.18	4.1e-11	-5.4	5.3	1.0e-07	-0.88	0.07	0.93	FALSE
4	GTEx	Lung	ZNF774	0.06	0.09	enet	6	0.03	1.5e-03	-5.6	-5.1	3.1e-07	0.89	0.02	0.97	FALSE
5	GTEx	Skin Sun Exposed Lower leg	CRTC3	0.10	0.08	lasso	3	0.05	7.5e-05	-5.6	5.4	7.4e-08	-0.96	0.02	0.98	FALSE
6	GTEx	Thyroid	ZNF774	0.09	0.06	enet	9	0.05	6.0e-05	-5.5	-5.2	2.2e-07	0.79	0.06	0.84	FALSE
7	METSIM	Adipose	IQGAP1	0.11	0.08	enet	32	0.12	3.9e-17	-5.7	-5.6	2.6e-08	0.89	0.02	0.98	FALSE
8	NTR	Blood	IQGAP1	0.03	0.04	enet	10	0.04	1.5e-12	-5.6	-5.2	1.9e-07	0.93	0.02	0.98	FALSE
9	YFS	Blood	IQGAP1	0.18	0.17	enet	46	0.20	5.8e-65	-4.2	-5.3	1.2e-07	0.84	0.94	0.05	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IQGAP1	0.04	0.03	lasso	4	0.02	6.5e-03	-5.6	-5.5	3.0e-08	0.95	0.02	0.88	FALSE
11	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	IQGAP1	0.15	0.09	lasso	4	0.12	1.9e-06	-5.6	-5.7	1.4e-08	0.92	0.01	0.98	TRUE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF774	0.04	0.00	enet	7	0.01	5.1e-02	-5.6	-5.3	9.9e-08	0.79	0.01	0.89	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF774	0.06	0.06	lasso	3	0.04	1.2e-05	-5.6	5.5	3.0e-08	-0.93	0.00	1.00	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	IQGAP1	0.11	0.03	enet	8	0.06	1.4e-06	-4.5	-5.3	9.7e-08	0.78	0.06	0.94	FALSE
15	The Cancer Genome Atlas	Stomach Adenocarcinoma	IQGAP1	0.12	0.07	lasso	4	0.07	1.4e-05	-5.7	-5.6	2.2e-08	0.96	0.01	0.99	FALSE