Best TWAS P=6.78e-08 · Best GWAS P=7.79e-09 conditioned to 0.0568
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | TMEM8A | 0.02 | 0.02 | enet | 8 | 0.02 | 1.7e-06 | -4.4 | 5.4 | 8.5e-08 | 0.66 | 0.49 | 0.49 | TRUE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | RGS11 | 0.09 | 0.05 | enet | 8 | 0.05 | 1.5e-03 | -4.9 | 5.4 | 6.8e-08 | 0.63 | 0.02 | 0.46 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | TMEM8A | 0.07 | 0.00 | blup | 51 | 0.03 | 2.3e-04 | 5.6 | 5.3 | 1.4e-07 | 0.66 | 0.00 | 0.98 | FALSE |