Best TWAS P=1.58e-10 · Best GWAS P=6.33e-14 conditioned to 4.4e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | LRRC29 | 0.53 | 0.02 | enet | 20 | 0.12 | 0.00032 | -7.3 | -6.0 | 1.8e-09 | 0.71 | 0.06 | 0.39 | FALSE |
| 2 | GTEx | Pancreas | TPPP3 | 0.24 | 0.01 | lasso | 4 | 0.00 | 0.19900 | -6.5 | -6.4 | 1.6e-10 | 0.92 | 0.08 | 0.10 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SLC9A5 | 0.01 | 0.00 | blup | 30 | 0.01 | 0.01120 | -3.6 | -5.9 | 3.8e-09 | 0.85 | 0.02 | 0.44 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | E2F4 | 0.11 | 0.01 | blup | 34 | 0.02 | 0.00321 | -7.4 | 6.2 | 6.5e-10 | -0.85 | 0.00 | 0.93 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | FBXL8 | 0.04 | 0.01 | enet | 8 | 0.02 | 0.00674 | -6.6 | 6.0 | 2.3e-09 | -0.88 | 0.00 | 0.92 | FALSE |