Best TWAS P=1.81e-19 · Best GWAS P=2.93e-25 conditioned to 0.000745
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | MCM9 | 0.21 | 0.00 | lasso | 8 | -0.01 | 0.48900 | -10.2 | 9.0 | 1.8e-19 | -0.78 | 0.04 | 0.44 | TRUE |
| 2 | GTEx | Esophagus Mucosa | CEP85L | 0.05 | 0.00 | enet | 6 | 0.01 | 0.06820 | 6.7 | -6.7 | 1.5e-11 | 0.79 | 0.18 | 0.33 | FALSE |
| 3 | GTEx | Liver | CEP85L | 0.30 | 0.00 | enet | 4 | 0.05 | 0.01230 | 7.3 | -7.6 | 2.2e-14 | 0.79 | 0.10 | 0.09 | FALSE |
| 4 | METSIM | Adipose | MCM9 | 0.04 | 0.02 | bslmm | 415 | 0.02 | 0.00014 | 3.6 | 5.4 | 6.0e-08 | -0.56 | 0.31 | 0.28 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | C6orf204 | 0.07 | 0.02 | enet | 14 | 0.03 | 0.00923 | 5.4 | -8.6 | 1.0e-17 | 0.69 | 0.03 | 0.78 | TRUE |