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chr20:35,835,657-37,586,842
Best TWAS P=1.23e-22 · Best GWAS P=3.67e-51 conditioned to 5.83e-16
35.8M
36M
36.2M
36.4M
36.6M
36.8M
37M
37.2M
37.4M
37.6M
0
10
20
30
40
50
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Liver
VSTM2L
0.24
-0.01
enet
6
-0.01
9.4e-01
-1.2
-9.8
1.2e-22
0.61
0.04
0.33
TRUE
4
The Cancer Genome Atlas
Breast Invasive Carcinoma
KIAA1755
0.02
0.00
blup
84
0.00
1.2e-01
-15.0
9.4
4.1e-21
-0.76
0.01
0.71
TRUE
3
GTEx
Testis
KIAA1755
0.19
0.12
lasso
3
0.10
2.5e-05
-9.0
9.3
9.2e-21
-0.34
0.68
0.03
TRUE
2
GTEx
Nerve Tibial
KIAA1755
0.14
0.00
lasso
5
0.00
3.0e-01
-9.6
6.9
3.9e-12
-0.44
0.05
0.12
FALSE