Best TWAS P=1.23e-22 · Best GWAS P=3.67e-51 conditioned to 5.83e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Liver | VSTM2L | 0.24 | -0.01 | enet | 6 | -0.01 | 9.4e-01 | -1.2 | -9.8 | 1.2e-22 | 0.61 | 0.04 | 0.33 | TRUE |
| 2 | GTEx | Nerve Tibial | KIAA1755 | 0.14 | 0.00 | lasso | 5 | 0.00 | 3.0e-01 | -9.6 | 6.9 | 3.9e-12 | -0.44 | 0.05 | 0.12 | FALSE |
| 3 | GTEx | Testis | KIAA1755 | 0.19 | 0.12 | lasso | 3 | 0.10 | 2.5e-05 | -9.0 | 9.3 | 9.2e-21 | -0.34 | 0.68 | 0.03 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | KIAA1755 | 0.02 | 0.00 | blup | 84 | 0.00 | 1.2e-01 | -15.0 | 9.4 | 4.1e-21 | -0.76 | 0.01 | 0.71 | TRUE |