TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Pulse rate
:
←
→
chr2:178,362,572-179,939,959
Best TWAS P=6.26e-10 · Best GWAS P=6.3e-41 conditioned to 2.12e-29
178.4M
178.6M
178.8M
179M
179.2M
179.4M
179.6M
179.8M
180M
0
10
20
30
40
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
OSBPL6
0.12
0.00
enet
9
0.02
0.022
7.5
-6.2
6.3e-10
-0.28
0.07
0.04
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
TTN
0.04
0.01
lasso
3
0.01
0.056
-2.7
5.2
2.6e-07
0.23
0.14
0.43
TRUE