Hub : Genes

OSBPL6

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.097 0.0410 6.0e-03 0.005 NA 0.010 NA -0.003 1.1e-01 NA 4.4e-02 NA 8.1e-01
2 GTEx Cells Transformed fibroblasts 0.116 0.0540 9.5e-03 -0.002 NA 0.016 NA -0.004 5.6e-01 NA 2.2e-02 NA 1.0e+00
3 GTEx Esophagus Mucosa 0.679 0.0450 0.0e+00 0.510 NA 0.511 NA 0.525 6.6e-39 NA 4.6e-39 NA 1.5e-40
4 GTEx Esophagus Muscularis 0.105 0.0420 1.8e-03 0.011 NA 0.020 NA 0.021 6.5e-02 NA 2.1e-02 NA 1.8e-02
5 GTEx Nerve Tibial 0.853 0.0306 1.4e-11 0.133 NA 0.000 NA 0.059 1.2e-09 NA 2.9e-01 NA 5.2e-05
6 GTEx Skin Not Sun Exposed Suprapubic 0.164 0.0580 1.9e-03 0.056 NA 0.056 NA 0.059 5.1e-04 NA 5.0e-04 NA 3.5e-04
7 GTEx Skin Sun Exposed Lower leg 0.348 0.0580 5.1e-10 0.218 NA 0.214 NA 0.233 6.7e-18 NA 1.4e-17 NA 3.2e-19
8 TCGA Prostate Adenocarcinoma 0.150 0.0410 2.2e-08 0.135 0.103 0.131 NA 0.129 5.7e-14 7.4e-11 1.4e-13 NA 2.1e-13

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.3 0.5 0.2 -0.7 -0.4 0.7 0.4 -0.6 -0.3 -0.5
Bipolar Disorder or Schizophrenia 0.4 0.9 4.5 0.2 -1.1 0.7 2.1 -0.4 0.8 0.7 0.0
Depressed Affect (Nagel 2018) 0.4 0.9 2.1 0.9 1.4 0.5 1.3 1.3 0.5 0.2 0.2
Depression (Nagel 2018) 0.5 0.8 1.9 0.7 0.1 -1.2 0.9 1.1 0.1 -1.4 0.8
Intelligence (Savage-Jansen 2018) 0.4 1.2 4.8 1.2 -0.6 -0.3 0.4 -0.5 -2.2 0.2 -1.6
Neuroticism (Nagel 2018) 0.2 0.4 1.4 0.6 0.8 -0.1 1.2 0.2 0.3 -0.5 0.7
Schizophrenia (2018) 0.7 1.4 4.6 0.1 -0.8 1.3 2.1 -0.8 1.5 1.1 0.3
Schizophrenia vs Biploar Disorder 0.4 0.5 1.0 0.3 -0.6 -0.7 0.7 -0.8 0.0 -0.8 1.0
Worry (Nagel 2018) 0.4 0.8 2.0 0.0 0.7 -1.0 1.2 0.5 -0.1 -1.2 1.4
Alzheimer’s Disease (in mother) 0.8 0.9 2.9 1.1 1.7 0.5 0.8 -0.3 1.1 0.7 0.7
Alzheimer’s Disease (in father) 1.7 1.8 4.8 -0.7 0.7 2.2 1.1 0.6 1.6 2.1 -0.2
Alzheimer’s Disease (including proxy) 1.1 1.6 3.8 0.7 1.0 1.7 1.2 0.3 1.4 2.0 0.9
Crohns Disease (2017) 1.1 2.5 6.3 2.5 -0.4 -1.9 1.8 -0.6 -1.2 -2.1 0.4
Irritable Bowel Disease (IBD) 0.2 0.5 2.5 1.6 0.1 -0.4 0.4 -0.1 -0.4 -0.7 0.3
Ulcerative Colitis (UC) 0.3 0.6 1.8 -0.2 0.5 1.4 -0.7 0.6 0.8 1.1 0.2
Major Depression (MDD) 0.2 0.2 0.4 -0.5 -0.4 -0.6 0.1 0.0 -0.6 -0.6 -0.2
Reaction Time 0.2 0.4 1.0 -0.8 0.3 -0.3 1.0 -0.6 0.8 0.1 0.9
Verbal and Numeric Reasoning (VNR) 0.1 0.3 1.4 0.0 0.2 0.1 0.2 -0.4 -0.9 0.2 -1.2
Breast Cancer 0.4 1.0 2.8 -0.6 -0.1 -0.9 0.1 -0.3 -1.7 -0.9 -1.7
Ovarian Cancer 0.6 0.9 2.3 -0.4 1.5 1.2 -0.0 -0.0 0.6 1.4 0.8
Prostate Cancer 2.1 2.9 6.7 -2.6 1.4 1.1 -1.9 1.8 0.1 0.7 -2.5
Age at First Birth 0.3 0.4 1.2 0.8 0.1 -0.3 -0.9 -1.1 0.2 0.1 -0.5
Bipolar Disorder (2011) 0.6 0.6 1.2 -0.7 0.6 1.0 0.7 1.1 0.5 0.6 0.5
Body Mass Index (BMI) (2010) 0.5 0.7 2.6 -1.0 -1.6 0.1 -0.7 0.1 -0.4 1.0 -0.6
Coronary Artery Disease (CAD) 0.4 0.4 2.5 -0.3 -0.0 0.1 -0.8 0.1 0.4 -0.1 1.6
Crohns Disease (2012) 1.1 1.8 4.0 1.5 0.9 -1.9 1.7 0.1 -0.7 -2.0 0.4
Mean Putamen Volume 1.0 1.1 2.0 -0.9 -1.4 1.3 -1.0 1.1 0.4 1.3 0.6
Fasting Glucose 0.2 0.2 0.7 0.1 -0.8 0.3 0.5 0.6 -0.0 0.5 -0.1
HbA1C 1.3 1.4 3.1 1.4 -1.2 -1.8 0.9 -0.3 -1.5 -1.4 0.3
HDL Cholesterol 0.4 0.7 2.9 1.7 0.5 -0.4 0.0 -0.8 -0.5 -1.1 0.7
LDL Cholesterol 0.3 0.5 1.3 0.5 -0.9 1.0 0.0 0.5 -0.2 1.1 0.4
Lupus 0.4 0.7 3.5 1.9 0.8 0.0 0.3 0.0 -0.2 0.0 1.0
Neuroticism (2016) 0.4 0.5 1.5 0.3 -0.1 1.1 0.3 -0.1 1.0 1.2 -0.4
Primary Biliary Cirrhosis 1.3 1.9 3.2 0.7 -0.6 1.8 0.1 1.6 1.6 1.8 1.6
Rheumatoid Arthritis 0.6 0.9 3.5 -1.3 0.7 -0.3 -0.4 -1.9 -0.2 -0.3 -1.0
Schizophrenia (2014) 0.6 1.2 2.5 -0.0 -1.1 1.3 1.6 -1.2 1.2 1.2 0.5
Triglycerides 0.5 0.7 3.0 -1.7 0.1 -0.6 0.1 -0.2 -0.9 -0.4 -1.3
Type 2 Diabetes (T2D) (2012) 2.9 3.3 7.7 -2.8 0.1 1.6 -1.4 0.6 1.9 2.5 2.1
Ulcerative Colitis 0.9 1.4 5.3 -1.0 0.8 2.3 -0.4 -0.1 1.1 1.6 0.1
Blood Eosinophil Count 0.2 1.7 3.6 -1.6 1.9 -1.4 0.2 0.6 -0.6 -1.8 -1.4
Blood Platelet Count 0.2 2.1 5.4 -1.6 -2.3 -1.0 -1.9 0.3 -1.1 -0.6 1.4
Blood Red Count 0.2 1.7 8.5 0.5 2.9 -0.9 0.6 -0.4 0.2 -1.1 1.4
Blood White Count 0.1 0.8 1.8 0.6 0.6 -1.2 1.4 -0.2 0.2 -1.1 0.9
Heel T-Score 0.1 0.7 1.4 0.7 -0.5 1.2 1.1 -1.0 0.5 0.5 -0.7
BMI 0.2 1.3 4.5 -0.7 -0.6 -2.1 -0.4 0.8 -1.1 -1.3 -1.0
Height 0.3 4.9 10.8 3.3 0.7 -1.5 -1.1 0.5 -3.1 -2.5 -3.0
Waist Hip Ratio (WHR) 0.3 1.3 4.5 -0.5 -0.3 -1.5 -1.1 1.1 -2.1 -0.8 -0.5
Systolic Blood Pressure 0.4 1.8 4.5 -2.0 -2.1 -1.4 0.9 1.4 -1.1 -0.4 0.3
Smoking Status 0.8 2.0 6.7 -1.1 1.1 -1.4 2.6 1.0 -0.4 -1.8 -0.2
Allergy or Eczema 0.4 1.1 5.7 0.7 -0.1 0.8 -0.4 -0.0 0.3 1.3 2.4
Cardiovascular Disease 0.5 1.7 5.6 -0.8 -2.0 -1.4 -0.3 0.5 -2.4 -0.6 -0.7
Hypothyroidism (self reported) 1.4 3.3 5.2 -1.8 1.4 2.2 -0.9 1.4 2.2 1.9 2.3
Respiratory disease 0.5 1.2 3.6 0.9 -0.2 -1.2 0.7 0.1 -1.4 -0.8 1.9
Type 2 Diabetes (T2D) (2018) 0.8 1.5 6.1 0.1 -0.8 -1.3 -0.8 -0.6 -2.5 -1.1 -1.4
Lung FEV1/FVC ratio 0.5 2.4 7.4 -1.2 -1.5 2.5 -0.1 -0.2 1.2 2.7 -0.1
Lung FVC 0.4 2.2 6.3 -0.3 1.6 1.2 2.5 -0.8 2.5 0.2 -0.2
Neuroticism 1.1 2.7 6.2 2.4 0.8 -1.1 2.5 2.0 0.3 -1.8 0.9
Chronotype (morning person) 0.3 0.8 1.6 1.0 0.5 -1.2 -0.7 -0.8 -0.9 -1.3 -0.3
Hair Pigment 0.0 1.0 7.0 0.4 -0.0 -0.0 -2.6 0.3 0.4 -0.6 0.7
Tanning 0.1 1.1 3.0 -0.2 0.1 0.8 -0.5 -1.2 1.7 0.6 1.7
Hand grip strength (left) 0.6 1.7 5.1 -1.0 2.3 -1.0 -0.0 0.2 -1.9 -1.4 -0.7
Number of treatments/medications taken 0.5 0.9 1.6 -1.3 -0.6 -1.3 -0.8 0.7 -0.8 -1.2 0.1
Average weekly spirits intake 0.8 1.0 3.6 -1.9 0.9 1.1 -0.4 0.3 0.5 1.3 -0.8
Sensitivity / hurt feelings 1.1 1.9 6.9 -1.0 2.0 -0.6 0.2 2.6 1.5 -0.8 0.4
Frequency of depressed mood in last 2 weeks 0.4 0.5 1.3 -0.5 1.1 -0.0 0.2 1.1 1.1 0.2 0.6
Hearing difficulty/problems: Yes 0.5 0.8 1.9 1.1 -1.3 -0.1 -1.4 0.1 0.9 -0.0 -1.0
Relative age of first facial hair 0.4 0.8 3.1 -0.6 -1.3 -0.0 -1.8 0.3 -1.1 -0.1 0.4
Other serious medical condition/disability diagnosed by doctor 0.8 1.0 2.4 -1.1 -0.9 1.1 0.1 1.6 0.9 1.0 0.6
Ever used hormone-replacement therapy (HRT) 1.0 1.2 3.6 -0.1 0.6 0.7 -0.6 1.2 1.9 0.5 1.8
Ever had hysterectomy (womb removed) 1.1 1.2 4.1 -0.2 0.6 0.2 2.0 -0.1 1.3 0.2 1.9
Systolic blood pressure, automated reading 0.3 0.8 3.0 -0.7 -1.2 -0.9 1.7 -0.4 0.2 -0.4 0.3
Eye problems/disorders: Diabetes related eye disease 1.6 1.7 8.0 1.3 -1.2 -0.3 0.4 0.8 -1.4 0.5 -2.8
Angina 0.3 0.4 1.1 1.1 -1.0 0.1 0.1 0.3 0.5 0.6 0.7
Medication for hormone replacement therapy 0.4 0.5 1.0 -0.9 0.6 0.8 -1.0 -0.9 0.5 0.6 -0.2
Vitamin and mineral supplements 1.1 1.5 4.8 0.2 1.9 1.2 0.4 -0.0 2.2 0.7 1.1
Supplements: Zinc 0.4 0.5 0.9 -0.6 0.9 -0.5 -0.7 0.7 -0.9 -0.6 0.0
Medication: Co-codamol 0.7 0.8 3.5 -0.0 -0.4 0.5 0.4 -1.9 1.1 1.0 -0.7
Medication: Metformin 1.5 2.1 6.5 0.8 -1.5 -1.7 -0.9 0.3 -2.5 -1.3 -1.4
Diabetes (father) 2.0 2.5 4.4 -1.1 -1.9 -0.5 -1.9 1.8 -2.1 -0.0 -1.9
Diabetes (mother) 1.1 1.4 4.0 -1.1 -0.1 -2.0 -0.7 1.0 -1.3 -1.3 -1.0
Severe depression (siblings) 0.7 0.8 2.3 -0.4 -0.3 -1.3 -0.7 0.5 -1.1 -1.5 -0.1
Pack years adult smoking proportion 1.1 1.7 5.8 2.4 -1.7 -1.3 1.5 -0.2 -0.4 -0.9 0.0
Impedance of leg (right) 0.4 1.9 6.5 0.4 2.5 1.7 -0.6 1.8 0.9 1.2 -0.3
Leg fat-free mass (left) 0.5 2.6 7.1 0.4 -1.6 -2.3 -0.9 -0.5 -2.7 -1.8 -1.2
Trunk fat percentage 0.5 2.2 6.7 0.5 0.0 -2.6 -2.1 0.2 -1.1 -2.2 -0.4
Hand grip strength (right) 0.5 1.4 4.6 0.0 0.8 -1.5 0.9 -0.2 -2.1 -1.3 -1.0
Townsend deprivation index at recruitment 0.7 1.0 2.7 0.7 -0.4 -1.6 -0.0 -0.8 -1.5 -1.4 -0.2
Current tobacco smoking 0.5 0.8 1.6 -0.2 0.1 -0.9 1.2 -1.3 -0.7 -1.3 -0.8
Average weekly fortified wine intake 0.5 0.6 1.4 0.8 0.2 0.6 1.2 -0.9 0.7 1.1 -0.3
Maternal smoking around birth 1.0 1.5 5.0 -0.1 -1.8 -1.5 0.1 0.5 -2.2 -0.9 0.4
Fed-up feelings 0.9 1.6 6.9 0.2 1.9 -0.8 0.6 2.6 -0.1 -1.2 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 4.1 -0.5 -0.3 -0.8 0.7 2.0 0.1 -0.7 0.5
Relative age voice broke 1.0 1.5 4.0 -1.5 1.3 0.3 -2.0 1.8 -0.5 -0.0 -0.3
Taking other prescription medications 0.7 1.0 4.4 -0.5 -1.1 -0.4 -2.1 1.3 0.1 -0.1 0.7
Age when periods started (menarche) 0.1 0.3 0.8 0.3 0.4 0.2 0.5 -0.1 -0.9 0.7 0.7
Bilateral oophorectomy (both ovaries removed) 1.5 1.8 4.7 0.1 1.4 0.0 2.2 -0.3 1.7 -0.4 2.0
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.7 4.9 -1.1 -0.3 1.1 -2.2 -2.2 0.7 0.7 -0.1
Tinnitus: Yes, but not now, but have in the past 0.9 1.0 3.7 0.5 -1.9 1.1 0.2 -0.4 1.0 1.3 0.2
Qualifications: CSEs or equivalent 1.3 1.7 3.6 -0.9 -1.8 1.0 -1.8 0.4 -1.0 1.9 -0.8
Serious illness, injury or assault to yourself 0.4 0.5 1.2 0.8 -1.1 -1.0 0.7 0.2 -0.3 -0.8 -0.4
High blood pressure 0.4 1.3 4.2 0.6 -2.1 -1.7 0.6 -0.9 -0.8 -0.8 0.4
Hayfever, allergic rhinitis or eczema 0.4 0.9 4.1 1.3 -0.5 0.5 -0.1 0.1 -0.5 0.9 2.0
Multivitamins +/- minerals 1.7 2.2 4.3 -1.4 -2.1 -1.5 -1.4 1.2 -1.9 -1.1 -0.8
Stomach or abdominal pain in last month 0.9 1.1 4.0 1.2 -0.6 1.0 -0.8 2.0 0.5 1.0 0.6
Supplements: Glucosamine 0.4 0.5 1.6 -1.0 0.6 -0.3 0.3 1.3 0.1 -0.5 0.6
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 1.6 -0.5 -0.6 0.2 -0.5 1.3 0.3 -0.1 -0.4
Medication: Atenolol 2.5 3.1 7.6 0.7 -0.7 -2.0 -1.9 -2.8 -1.2 -1.9 -1.8
Medication: Levothyroxine sodium 0.7 1.2 2.5 -0.8 1.3 1.1 -0.7 1.6 1.3 1.0 0.9
Sitting height 0.8 6.0 14.9 3.7 -1.0 -2.6 -0.8 0.3 -3.9 -3.2 -1.0
Chronic bronchitis/emphysema (father) 0.4 0.5 2.2 -0.5 0.6 0.2 -1.1 -1.5 0.0 -0.1 -0.1
High blood pressure (mother) 1.0 1.3 3.8 -0.9 -1.3 -0.8 -1.1 -0.7 -1.2 -0.7 -1.9
Body mass index (BMI) 0.4 1.7 5.5 0.4 -1.7 -2.3 -1.1 -0.2 -1.1 -1.6 -0.4
Impedance of leg (left) 0.3 1.6 6.2 0.8 2.5 1.4 -0.5 1.4 1.0 1.0 0.3
Leg predicted mass (left) 0.5 2.6 7.2 0.3 -1.6 -2.2 -0.9 -0.6 -2.7 -1.8 -1.2
Trunk fat mass 0.6 2.7 8.2 0.8 -0.5 -2.9 -1.7 0.4 -1.9 -2.3 -0.7
Waist circumference 0.7 2.7 6.2 -0.1 -1.4 -2.5 -2.3 -0.2 -2.0 -1.6 -1.4
Number of incorrect matches in round 0.7 1.2 3.8 -0.9 2.0 0.0 1.0 1.1 0.2 0.0 1.6
Past tobacco smoking 0.6 1.1 2.5 1.4 -0.5 1.2 -1.2 -1.6 0.2 0.9 0.0
Alcohol usually taken with meals 0.6 0.9 3.5 -0.3 -0.1 -0.1 1.6 -0.8 -1.9 -0.4 -0.6
Nervous feelings 0.6 1.2 2.3 -1.3 1.5 0.4 1.4 0.9 1.0 0.3 1.1
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.0 -0.5 -0.2 -0.9 -0.0 1.4 0.1 -1.0 -0.8
Hearing difficulty/problems with background noise 1.0 1.6 4.5 0.9 0.8 -1.7 0.3 1.9 -0.0 -2.1 -0.6
Hair/balding pattern: Pattern 2 0.5 0.7 1.7 0.0 -1.2 0.9 -1.3 0.0 -0.0 1.1 0.5
Had menopause 1.1 1.3 3.4 -1.8 0.6 -1.2 -0.0 0.5 1.3 -1.9 0.6
Had other major operations 1.0 1.2 3.9 -0.2 -0.8 1.4 -0.3 -0.5 1.3 0.8 2.0
Forced vital capacity (FVC) 0.2 0.9 3.8 0.1 1.1 1.1 2.0 -0.0 0.8 0.1 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 4.8 -0.4 -1.3 0.4 -1.5 -2.2 0.4 -0.0 -0.1
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 2.0 -0.5 -0.8 -0.3 -0.2 1.4 0.4 -0.1 0.2
Qualifications: None of the above 0.7 1.6 3.7 1.9 -0.2 -1.6 1.4 -0.6 0.7 -1.6 0.9
Financial difficulties in last 2 years 0.5 0.6 2.4 0.2 0.5 -0.8 -0.6 0.6 0.7 -0.8 1.5
Mouth/teeth dental problems 1.0 1.6 3.0 -1.7 0.4 1.3 -1.7 0.8 1.4 1.1 0.9
Heart attack 1.0 1.2 4.6 -0.9 0.2 -0.4 -2.1 0.1 -1.2 -0.6 -1.6
Allergy 0.3 0.8 2.7 -0.8 1.0 0.1 0.4 0.2 1.6 -0.2 -1.2
Pain all over the body in last month 0.6 0.7 1.6 1.2 0.3 -0.4 0.1 1.1 1.3 0.1 0.9
Diabetes (self-reported) 0.7 1.1 2.7 -0.1 -0.4 -0.9 -1.3 0.5 -1.5 -0.8 -1.6
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.0 -1.0 -0.4 -0.1 -0.8 0.5 -1.0 -0.2 0.9
Medication: Ramipril 3.0 3.9 10.2 -2.9 -0.2 -3.2 0.2 0.3 -0.7 -2.9 1.7
Medication: Simvastatin 1.1 1.6 3.6 0.2 -0.9 -1.4 -0.6 -0.8 -1.7 -1.6 -1.9
Fluid intelligence score 0.5 1.0 3.5 -0.3 -0.2 -0.8 0.1 -0.3 -1.8 -0.7 -1.9
Illnesses of siblings 1.1 1.5 3.3 -0.9 1.8 1.4 -0.6 1.0 1.2 1.1 1.2
Neuroticism score 0.7 1.4 2.8 0.8 1.2 -1.2 1.4 1.7 0.4 -1.5 0.3
Weight 0.7 3.5 8.6 1.3 -1.2 -2.9 -1.6 0.2 -2.5 -2.4 -1.1
Impedance of arm (right) 0.1 0.5 1.7 -0.1 1.3 0.8 -1.2 0.5 0.2 0.5 -0.1
Arm fat percentage (right) 0.3 1.3 4.9 0.1 -0.9 -2.2 -1.5 0.2 -0.7 -1.5 -0.1
Trunk fat-free mass 0.4 2.5 8.2 1.2 -1.5 -2.1 0.2 0.1 -2.9 -1.7 -1.1
Hip circumference 0.3 1.5 3.5 -0.5 -0.9 -1.7 -1.9 -0.3 -1.4 -1.4 -0.8
Time employed in main current job 0.5 0.6 2.2 -0.1 1.5 -0.0 -0.1 -1.4 0.5 0.2 -0.1
Alcohol intake versus 10 years previously 0.2 0.4 0.7 -0.7 0.9 0.1 -0.8 -0.8 -0.7 0.0 -0.1
Father’s age at death 0.3 0.5 2.8 -0.5 0.2 -0.2 -1.7 0.1 0.7 0.0 -0.2
Worrier / anxious feelings 0.2 0.4 0.9 0.4 0.7 -0.7 0.9 0.5 -0.1 -0.7 -0.6
Frequency of tiredness / lethargy in last 2 weeks 1.2 2.0 7.5 2.7 -0.3 -1.0 0.7 2.3 -0.1 -0.8 1.0
Falls in the last year 0.9 1.2 5.2 -0.7 -0.5 -1.0 -2.3 1.4 -0.4 -0.6 -0.5
Hair/balding pattern: Pattern 3 0.5 0.7 1.4 1.0 1.0 -0.7 -0.6 0.5 -1.2 -0.8 -0.8
Number of live births 0.5 0.7 2.2 -1.5 0.8 0.4 -1.3 -0.2 1.0 0.2 0.4
Forced expiratory volume in 1-second (FEV1) 0.3 1.0 4.7 -0.0 0.7 1.3 2.2 0.0 0.7 0.6 -0.0
Pulse rate 4.6 7.7 38.2 0.6 -6.2 -0.4 -4.2 -0.7 -2.1 -0.3 -0.1
Happiness 0.8 1.0 2.0 -0.0 -1.3 -1.1 -1.1 1.4 -0.5 -1.1 0.4
Noisy workplace 1.3 1.6 8.7 1.2 0.4 -0.4 1.2 3.0 -0.4 -0.7 0.8
Qualifications: A levels/AS levels or equivalent 0.5 1.2 4.9 -2.2 -0.3 0.8 -1.2 0.3 0.4 1.2 -0.8
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 2.5 -0.3 -1.6 -0.2 -0.1 0.2 -1.1 -0.0 -1.4
Mouth/teeth dental problems: Dentures 2.7 4.5 17.7 -0.4 -1.2 -2.0 -0.6 -2.1 -4.2 -1.8 -2.1
Asthma 0.1 0.2 0.9 -0.1 -0.3 -0.3 0.2 0.7 -0.9 -0.3 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.3 0.4 -0.1 0.6 -0.7 -0.8 0.7 -0.1 1.2
Medication: Cholesterol lowering 0.5 0.8 2.0 0.1 -1.4 -0.7 -0.2 0.4 -1.3 -0.5 -1.3
Depression (self-reported) 0.7 0.8 2.6 1.6 -0.4 -0.2 1.1 0.1 0.5 0.2 1.5
Medication: Lansoprazole 0.9 1.1 3.8 1.5 -1.1 0.2 1.0 -1.9 -0.4 0.3 -0.1
Prospective memory result 0.6 0.7 3.6 0.5 -1.2 0.4 0.1 -1.9 -0.0 0.3 0.4
Lung cancer (father) 0.9 1.0 2.7 1.6 -1.4 0.5 -1.2 0.1 0.6 1.1 0.5
Illnesses of mother 0.4 0.4 2.2 0.7 1.5 0.6 0.1 0.1 0.4 0.2 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 3.0 0.1 0.7 0.2 1.7 0.1 0.3 -0.8 -0.2
Pulse wave Arterial Stiffness index 0.2 0.3 0.6 -0.5 -0.2 -0.1 -0.8 0.1 -0.6 -0.6 -0.8
Impedance of arm (left) 0.1 0.6 2.8 -0.3 1.7 0.7 -1.1 0.3 0.4 0.2 0.1
Arm fat mass (right) 0.6 2.3 7.3 0.4 -1.3 -2.7 -1.4 -0.1 -1.6 -2.0 -0.7
Trunk predicted mass 0.4 2.5 7.9 1.3 -1.6 -2.0 0.0 0.0 -2.8 -1.7 -1.0
Standing height 0.4 3.5 11.8 2.0 0.8 -1.5 -0.9 1.3 -3.4 -2.0 -1.6
Length of working week for main job 1.6 1.8 4.5 1.3 -1.7 0.1 2.1 1.0 -2.0 0.2 -0.1
Exposure to tobacco smoke at home 0.8 0.8 2.8 1.1 -1.3 -0.5 0.3 0.8 0.4 0.2 1.7
Breastfed as a baby 1.7 2.1 7.1 -2.7 1.0 2.1 -0.4 0.6 1.0 1.4 1.1
Tense / ‘highly strung’ 0.6 1.0 3.2 0.5 -0.5 -0.7 1.8 0.9 -0.0 -0.9 1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 5.0 1.3 0.3 1.4 -0.2 0.8 2.2 1.4 0.7
Hair/balding pattern: Pattern 4 0.3 0.7 2.5 -0.8 0.1 0.4 0.5 -0.0 1.4 0.1 1.6
Birth weight of first child 0.4 0.7 1.9 0.1 0.0 1.2 -0.2 -1.4 0.5 0.9 -1.0
Peak expiratory flow (PEF) 0.3 0.6 1.3 -0.3 1.1 1.1 1.1 0.8 0.4 0.6 0.4
Pulse wave reflection index 0.9 1.2 6.0 -0.6 2.4 0.8 0.8 0.5 0.3 0.6 -0.9
Ever highly irritable/argumentative for 2 days 1.1 1.3 2.1 0.2 1.4 -1.4 1.4 1.3 0.0 -1.0 1.2
Loud music exposure frequency 1.5 1.6 3.6 0.0 -1.7 -1.4 -1.9 1.4 -1.1 -1.0 0.7
Qualifications: O levels/GCSEs or equivalent 1.4 2.2 9.1 -0.7 -0.4 1.0 -3.0 -1.8 0.4 1.4 -1.2
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 3.0 1.7 -0.8 0.7 1.1 -0.4 1.5 1.1 -0.2
Blood clot in the leg (DVT) 2.8 3.6 9.0 -0.8 -2.8 -2.3 -1.2 -1.0 -3.0 -2.0 -0.0
Medication: Paracetamol 0.6 0.9 2.3 0.7 -0.1 0.5 0.3 1.4 1.3 0.9 1.5
Headache pain in last month 0.4 0.7 3.9 0.6 -0.7 -0.9 -0.1 -0.1 0.0 -0.6 2.0
Medication for cholesterol, blood pressure or diabetes 0.6 0.9 2.1 -0.2 1.5 1.3 0.3 -0.9 1.2 0.8 0.7
Glaucoma (self-reported) 0.2 0.2 0.5 -0.1 -0.5 -0.7 -0.6 0.5 -0.2 -0.3 -0.2
Gout (self-reported) 1.7 2.3 6.5 2.5 -2.1 -1.5 1.4 -0.0 -0.6 -1.3 1.2
Hypothyroidism/myxoedema (self-reported) 1.0 2.0 6.0 -1.3 1.6 1.1 -1.0 2.4 1.3 0.9 0.9
Medication: Amlodipine 0.9 1.3 4.0 -2.0 -1.5 -0.2 -1.5 0.8 0.7 0.2 0.7
Medication: Ventolin 100micrograms inhaler 1.2 1.5 4.5 0.0 1.1 -1.0 -0.7 2.1 -1.6 -0.7 -1.2
Birth weight 0.7 1.6 3.1 -1.3 1.1 1.4 1.1 1.6 0.2 1.8 -1.0
Chronic bronchitis/emphysema (mother) 1.8 2.2 11.2 1.8 -0.4 -0.7 1.4 -0.1 -0.1 -0.4 3.4
High blood pressure (siblings) 0.1 0.1 0.5 -0.4 -0.7 0.0 0.4 -0.0 -0.2 -0.0 -0.2
Forced vital capacity (FVC), Best measure 0.2 0.6 1.8 -0.0 1.3 0.3 1.2 0.8 0.4 -0.9 -0.1
Body fat percentage 0.4 1.6 4.6 0.4 -0.4 -2.1 -2.1 0.6 -0.7 -1.6 -0.3
Leg fat percentage (right) 0.3 1.0 2.9 0.3 -0.2 -1.5 -1.7 1.0 -0.3 -0.9 -0.8
Arm fat-free mass (right) 0.4 2.0 5.3 0.9 -1.1 -2.2 -0.3 0.2 -2.3 -2.0 -0.5
Exposure to tobacco smoke outside home 1.5 2.0 9.1 0.5 -3.0 0.3 -2.0 0.0 -0.3 1.0 1.3
Comparative body size at age 10 0.3 0.8 2.5 -0.5 0.0 -1.2 1.6 -0.7 -0.7 -0.7 0.6
Number of full brothers 0.9 1.2 4.5 0.6 -2.1 -0.8 -1.6 0.2 -0.8 -0.4 -0.8
Worry too long after embarrassment 0.5 0.8 1.6 0.6 0.7 -0.6 0.3 1.0 1.3 -0.9 1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 2.5 1.4 -0.5 0.1 0.5 1.6 0.6 -0.6 1.3
Wheeze or whistling in the chest in last year 1.0 1.8 3.9 1.7 -0.2 -2.0 0.9 -0.4 -1.9 -1.7 0.7
Number of children fathered 1.5 1.7 4.1 -1.7 2.0 0.2 -1.0 0.5 1.7 -0.2 1.7
Reason for reducing amount of alcohol drunk: Health precaution 2.2 2.5 7.4 1.3 0.5 -0.6 2.7 2.6 1.3 -0.1 1.6
Age at first live birth 0.4 0.8 4.5 0.8 -0.3 0.5 -0.2 2.1 -0.7 0.4 -0.3
Pulse wave peak to peak time 0.2 0.3 0.5 0.6 0.4 0.1 0.7 -0.1 0.5 0.6 0.7
Health satisfaction 2.5 3.2 6.9 2.2 -2.3 -2.6 -0.0 0.1 -1.4 -2.5 0.8
Shortness of breath walking on level ground 1.5 1.8 3.6 1.4 -0.5 -1.7 1.5 -0.7 -1.9 -1.6 -0.4
Qualifications: College or University degree 0.7 2.3 6.8 -2.6 -0.6 1.4 -0.4 -2.1 0.2 2.0 -0.7
Eye problems/disorders: None of the above 1.2 1.4 5.8 -2.4 1.4 -0.5 -0.1 -0.2 -0.8 -0.9 -1.2
Mouth/teeth dental problems: Loose teeth 1.2 1.4 5.8 0.6 0.4 0.9 1.5 0.7 1.0 0.8 2.4
Emphysema/chronic bronchitis 0.8 0.9 2.8 0.5 0.8 -1.0 -0.8 0.8 -1.7 -0.9 -0.5
Medication for pain relief, constipation, heartburn 0.4 0.7 2.1 -0.3 1.0 0.4 -0.3 -1.3 -0.6 0.2 -1.4
Neck or shoulder pain in last month 1.2 1.7 3.2 1.2 0.3 0.5 1.7 1.5 1.7 0.4 1.8
Medication: Blood pressure 0.5 0.9 3.0 0.2 -1.7 -1.2 -0.0 1.1 -1.0 -0.6 -0.7
Angina (self-reported) 0.3 0.4 1.8 0.9 -1.3 0.1 -0.1 0.0 0.6 0.7 0.5
Migraine (self-reported) 0.3 0.3 2.1 0.0 -0.6 0.0 -0.1 0.1 -0.1 0.3 1.4
Medication: Ibuprofen 0.6 0.7 3.0 0.3 0.4 0.5 0.3 -1.7 0.8 -0.1 1.1
Medication: Allopurinol 1.4 1.9 5.2 1.8 -2.3 -0.4 1.0 0.2 -0.8 -0.2 2.3
Medication: Omeprazole 0.6 0.7 2.0 0.9 0.2 -1.4 -0.7 -0.7 0.5 -0.8 1.0
Medication: Seretide 50 evohaler 0.5 0.6 1.8 -0.0 0.1 0.5 -0.2 1.3 1.0 1.0 -0.8
Mean time to correctly identify matches 0.4 0.8 2.4 -1.3 0.8 0.2 0.9 0.5 1.5 0.2 0.8
Heart disease (mother) 0.5 0.7 2.5 -1.6 -1.5 0.3 -0.1 -0.3 0.1 0.5 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 4.2 -0.5 2.0 1.2 0.3 0.3 1.6 0.9 0.8
Whole body fat mass 0.6 2.5 6.8 0.3 -1.1 -2.6 -2.1 0.4 -1.7 -2.0 -0.9
Leg fat mass (right) 0.5 1.9 4.8 0.5 -1.0 -2.2 -1.7 0.9 -1.4 -1.5 -1.1
Arm predicted mass (right) 0.4 2.2 6.0 0.9 -1.2 -2.2 -0.1 0.2 -2.5 -1.9 -0.8
Pulse rate, automated reading 5.7 18.3 83.5 1.0 -9.1 -1.6 -7.2 -1.6 -2.0 -0.9 0.8
Alcohol intake frequency. 0.4 0.8 2.1 -0.2 -0.3 -0.1 -1.5 -0.8 -1.4 -0.2 -1.3
Comparative height size at age 10 0.2 1.4 2.8 0.9 0.0 -1.2 -0.4 1.2 -1.7 -1.6 -1.4
Number of full sisters 0.4 0.5 1.3 1.2 -0.2 -0.8 -0.7 0.2 -1.0 -0.5 -0.4
Suffer from ‘nerves’ 0.4 0.7 2.4 -1.1 0.5 -0.7 0.7 -1.6 -0.1 -0.7 0.4
Overall health rating 0.4 1.0 3.1 1.1 -1.7 -1.4 -0.5 -0.6 -0.2 -0.9 -0.3
Chest pain or discomfort 0.4 0.6 1.3 1.1 0.5 0.3 1.0 -0.2 0.6 0.3 1.1
Had major operations 0.8 0.9 4.8 0.4 0.5 0.2 0.4 -0.5 2.2 0.3 1.2
Age at last live birth 0.7 1.0 7.7 -0.1 0.5 -0.1 -0.1 2.8 -0.1 0.0 0.2
Family relationship satisfaction 1.1 1.3 2.8 0.9 -1.5 -0.8 -1.4 0.5 0.9 -1.0 1.7
Leg pain on walking 0.6 0.7 1.6 0.1 0.5 -1.3 0.3 0.8 0.9 -1.1 1.1
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 3.9 -0.3 0.4 2.0 0.5 0.1 0.2 1.4 -0.2
Commuting to job workplace: Car/motor vehicle 2.0 2.3 5.8 0.1 1.6 0.3 1.2 2.2 1.9 -0.4 2.4
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 0.8 -0.5 0.9 0.3 0.4 -0.8 -0.4 0.5 -0.9
Medication: Aspirin 0.4 0.6 1.8 -0.6 -1.4 -0.6 0.3 0.9 0.5 -0.7 0.7
Supplements: Vitamin C 0.2 0.2 0.7 0.4 -0.8 0.0 0.3 0.0 -0.8 0.2 -0.4
Knee pain experienced in last month 1.0 1.5 4.0 0.7 -0.5 -2.0 -1.0 0.3 -1.7 -1.8 -0.4
Hypertension (Self-reported) 0.4 1.1 4.8 0.1 -2.2 -1.5 0.2 -0.8 -0.5 -0.5 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 2.1 0.9 0.4 0.9 -0.9 -0.1 0.5 1.4 0.4
Illnesses of father: Heart disease 0.7 1.0 4.4 0.6 -0.9 -1.1 2.1 -0.7 0.3 -0.6 0.4
Illnesses of siblings: Diabetes 1.1 1.3 2.6 1.4 -1.6 -1.1 -0.4 0.7 -1.4 -0.5 -1.5
Smoking status: Previous 0.9 1.4 5.9 -0.8 0.7 -1.1 1.4 2.4 0.1 -0.8 0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.0 2.8 0.6 0.1 -0.7 -1.5 1.3 -1.7 -0.8 -0.3
Whole body fat-free mass 0.4 2.6 7.9 1.0 -1.6 -2.2 -0.3 -0.1 -2.8 -1.8 -1.0
Leg fat-free mass (right) 0.5 2.6 7.5 0.8 -1.4 -2.3 -0.6 -0.7 -2.7 -1.9 -0.9
Arm fat percentage (left) 0.4 1.6 6.0 0.0 -0.8 -2.4 -1.7 0.3 -0.8 -1.7 -0.1
Average weekly red wine intake 0.9 1.3 3.2 -1.3 1.0 -0.9 1.2 -1.8 -1.3 -0.8 -0.5
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.5 -0.2 0.3 0.4 -0.7 0.5 0.5 0.3 0.5
Mood swings 0.7 1.3 6.8 -0.3 1.2 0.1 -0.8 2.6 1.0 0.0 0.5
Loneliness, isolation 0.1 0.2 0.9 0.4 0.4 0.3 -0.2 -0.1 0.0 -0.1 -1.0
Long-standing illness, disability or infirmity 0.4 0.6 3.1 0.4 -1.8 0.4 -0.4 0.7 0.1 0.7 -0.3
Ever had bowel cancer screening 1.0 1.2 4.4 0.5 1.1 -0.6 0.3 1.3 0.7 -0.9 2.1
Diabetes diagnosed by doctor 1.1 1.8 4.9 0.1 -0.9 -1.2 -1.6 0.6 -1.9 -1.0 -2.2
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.7 3.2 -0.4 -0.6 -1.8 0.1 -0.2 -0.7 -1.3 -0.3
Friendships satisfaction 1.2 1.5 3.9 0.7 -2.0 -1.9 -0.5 -0.3 -0.5 -1.9 0.4
Qualifications: nursing, teaching 0.6 1.0 2.0 -1.4 -0.2 1.2 0.1 0.5 1.4 1.4 -0.4
Commuting to job workplace: Walk 1.5 1.6 6.1 -0.7 -0.8 -0.1 -0.0 -2.5 -0.8 0.6 -2.1
Eye problems/disorders: Cataract 1.2 1.4 8.0 2.8 -0.6 0.3 -0.4 -0.5 1.1 0.6 0.9
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 3.7 1.9 0.3 -0.8 1.4 1.5 1.1 -0.8 -0.0
Medication for cholesterol 0.9 1.3 5.4 1.0 1.0 0.2 2.3 1.2 -0.6 0.0 -1.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 2.4 -1.6 0.2 1.4 -0.4 -0.9 0.8 1.2 -1.3
Back pain experienced in last month 0.7 1.1 3.4 0.9 1.1 -0.4 1.9 1.6 -0.2 -0.5 0.2
Mineral and other dietary supplements 1.2 1.7 3.4 1.6 -0.2 1.1 -1.0 -1.8 1.6 1.6 -0.0
Breast cancer (self-reported) 0.4 0.4 1.9 -1.4 -0.3 1.0 0.5 -0.1 0.3 0.5 0.0
Asthma (self-reported) 0.2 0.3 1.5 -0.1 -0.1 -0.5 0.5 0.6 -1.2 -0.5 0.0
Osteoporosis (self-reported) 0.2 0.2 0.8 0.9 0.6 -0.1 -0.2 -0.0 0.3 -0.6 0.3
Osteoarthritis (self-reported) 0.3 0.3 1.8 -0.3 0.5 -0.6 -1.3 0.0 -0.3 -0.2 0.0
Medication: Aspirin 0.4 0.5 1.8 -0.5 -1.3 -0.5 0.4 0.8 0.2 -0.6 0.4
Medication: Gliclazide 1.8 2.0 6.6 0.6 -1.7 0.4 -1.7 1.6 -0.7 0.2 -2.6
Illnesses of father: None of the above (group 1) 0.6 0.8 2.3 1.5 0.6 -0.5 -1.2 0.0 -0.7 -1.0 0.8
Smoking status: Current 0.5 0.7 1.4 -0.2 0.1 -0.7 1.0 -1.2 -0.7 -1.1 -1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.5 5.9 0.6 0.4 0.8 2.4 -0.8 1.8 0.5 1.1
Whole body water mass 0.5 2.7 8.1 1.0 -1.5 -2.3 -0.3 -0.2 -2.8 -1.9 -1.1
Leg predicted mass (right) 0.5 2.5 7.1 0.7 -1.5 -2.2 -0.7 -0.7 -2.7 -1.8 -0.9
Arm fat mass (left) 0.6 2.6 8.5 0.4 -1.4 -2.9 -1.6 0.0 -1.6 -2.2 -0.7
Number of self-reported non-cancer illnesses 0.2 0.4 1.7 0.4 -1.3 -0.1 -0.7 0.2 -0.4 0.1 0.6
Average weekly champagne plus white wine intake 0.6 0.8 2.8 -1.0 1.7 -0.4 -0.3 1.2 0.5 -0.6 0.1
Miserableness 0.5 0.9 3.4 0.2 1.9 0.2 1.6 0.6 -0.1 -0.2 -0.8
Guilty feelings 0.5 0.7 2.0 0.6 0.6 -1.1 1.4 -0.6 -0.3 -1.2 -0.1
Wears glasses or contact lenses 1.1 1.3 2.9 -0.9 -0.5 1.3 0.8 1.2 1.5 1.7 0.3
Ever taken oral contraceptive pill 0.5 0.5 1.7 0.4 -1.3 -0.1 0.4 -0.9 0.2 0.5 1.1
Hearing aid user 2.7 3.1 12.3 1.2 0.9 2.3 0.6 -0.3 3.5 1.9 0.6
Mother’s age at death 0.2 0.2 1.1 -0.2 0.1 0.0 -0.5 0.3 -0.2 0.2 1.0
Financial situation satisfaction 0.5 0.7 2.8 -0.1 -0.8 0.2 -1.2 1.7 0.6 -0.1 0.4
Tinnitus: Yes, now most or all of the time 2.0 2.4 8.0 0.3 2.8 -1.7 0.8 1.8 0.1 -1.9 0.7
Commuting to job workplace: Public transport 2.1 2.5 7.6 -1.3 -1.5 -1.3 -2.0 -0.5 -1.6 -0.5 -2.8
Eye problems/disorders: Glaucoma 0.4 0.5 1.6 -0.6 -1.3 -0.7 -0.8 0.3 -0.6 -0.4 -0.7
Medication: Blood pressure 1.2 2.2 5.0 -0.4 -0.6 -2.1 -0.5 -2.0 -0.1 -1.7 2.2
Pain type(s) experienced in last month: Hip pain 0.4 0.4 1.7 1.0 -0.2 -0.0 -1.3 0.0 0.7 0.2 0.3
Supplements: Fish oil (including cod liver oil) 1.2 1.5 4.7 -2.2 -0.0 -1.0 0.8 2.1 -0.6 -0.9 -0.4
High cholesterol (Self-reported) 0.1 0.3 0.7 -0.4 -0.7 -0.2 -0.2 0.7 -0.8 -0.1 0.2
Medication: Bendroflumethiazide 0.2 0.3 0.9 -0.6 0.7 -0.1 -0.7 -0.5 0.4 -0.3 0.9
Medication: Paracetamol 0.5 0.8 1.7 1.3 -0.2 0.2 0.6 1.0 1.1 0.4 1.3
Medication: Lisinopril 0.9 1.1 2.8 0.6 -1.7 0.8 0.3 -1.2 -0.9 1.2 -1.1
Medication: Atorvastatin 0.5 0.6 1.7 -1.3 1.2 -0.6 -0.9 0.4 -0.6 -0.0 0.6
Illnesses of father: High blood pressure 0.8 0.9 3.8 -1.9 0.3 -0.4 0.2 -0.3 -1.1 -0.2 -1.5
Alcohol drinker status: Never 0.5 0.6 3.2 -0.2 0.6 -0.3 1.8 -0.2 0.0 -0.5 -1.0
Ever smoked 0.7 1.3 3.1 -1.2 0.1 -1.8 1.4 0.4 -0.9 -1.5 -0.6
Basal metabolic rate 0.5 2.9 8.1 1.0 -1.5 -2.5 -0.7 -0.2 -2.8 -2.0 -1.1
Leg fat percentage (left) 0.2 0.9 2.8 0.3 -0.1 -1.5 -1.7 0.8 -0.2 -0.9 -0.3
Arm fat-free mass (left) 0.4 2.2 5.1 1.1 -1.2 -2.2 -0.3 0.1 -2.3 -2.0 -1.0
Number of operations (self-reported) 0.7 1.1 3.4 -0.8 0.1 1.0 -0.6 -1.1 1.8 0.8 1.2
Average weekly beer plus cider intake 0.7 0.9 1.6 1.2 -1.1 -1.2 -1.1 0.1 -1.1 -0.8 -0.5
Irritability 0.2 0.4 1.6 0.3 0.7 -0.0 -0.0 1.3 0.6 -0.7 0.1
Risk taking 0.6 0.9 2.5 0.7 -0.6 -1.1 -0.1 1.3 0.7 -1.6 0.0
Ever had prostate specific antigen (PSA) test 0.9 1.1 4.0 -0.3 1.1 -0.3 -2.0 0.5 1.3 -0.6 0.9
Fractured/broken bones in last 5 years 1.3 1.6 4.4 -1.1 -0.6 -1.2 -2.1 1.4 -0.9 -1.3 -1.0
Age started oral contraceptive pill 1.1 1.4 4.2 -0.1 -0.0 -2.0 1.2 0.5 -1.0 -2.0 0.2
Diastolic blood pressure, automated reading 0.8 2.5 10.6 -0.6 -3.3 -2.0 -0.8 -1.1 -0.7 -1.5 0.4
Ever depressed for a whole week 0.5 0.6 2.4 0.6 -0.9 -0.4 0.2 1.5 -0.5 -0.4 -0.8
Unable to work because of sickness or disability 1.0 1.3 3.5 -0.4 -1.8 0.5 -1.9 1.4 0.8 0.8 -0.1
Commuting to job workplace: Cycle 0.6 0.7 3.0 -0.7 -0.5 0.6 -0.3 -1.7 -0.1 1.2 0.4
Myopia 1.1 1.5 10.8 -0.6 0.3 -0.3 -3.3 0.1 -0.6 0.2 -0.8
Vascular/heart problems diagnosed by doctor 0.3 0.7 2.7 -0.5 1.6 1.2 -0.2 0.8 0.7 0.5 -0.1
Cholesterol lowering medication 0.6 0.9 3.0 -1.5 0.2 -0.7 -1.7 -0.5 -0.9 -0.6 0.2
Medication: Omeprazole (e.g. Zanprol) 0.3 0.3 0.9 0.4 0.6 -0.7 -0.1 -0.3 0.9 -0.1 0.8
Pain experienced in last month 0.8 1.4 6.4 -1.5 -0.7 0.9 -0.3 -2.5 0.6 0.5 -0.8
Supplements: Calcium 0.4 0.4 1.2 -0.1 1.1 0.6 0.6 0.9 -0.2 0.1 0.8
Basal cell carcinoma (self-reported) 0.3 0.3 1.6 0.1 -0.2 -0.5 0.7 -1.3 -0.4 -0.4 -0.2
Heart attack/myocardial infarction (self-reported) 1.0 1.3 4.1 -0.6 0.4 -0.5 -2.0 0.1 -1.3 -0.8 -1.7
Deep venous thrombosis (DVT) (self-reported) 2.5 3.3 8.4 -0.4 -2.6 -2.3 -0.8 -0.6 -2.9 -2.2 0.2
Heart disease (siblings) 1.3 1.6 3.6 1.5 -1.9 -1.6 1.0 -1.4 -1.1 -0.6 -0.3
Alcohol drinker status: Previous 0.9 1.1 3.0 -0.5 -0.8 1.2 -1.7 0.5 -0.4 1.6 0.5
Pack years of smoking 0.8 1.2 3.7 1.9 -1.4 -1.1 1.3 -0.5 0.0 -0.7 0.4
Impedance of whole body 0.2 1.2 5.5 0.2 2.3 1.2 -0.9 0.8 0.8 0.6 0.3
Leg fat mass (left) 0.5 1.8 4.8 0.5 -0.9 -2.2 -1.7 0.7 -1.4 -1.5 -0.8
Arm predicted mass (left) 0.5 2.7 6.2 1.1 -1.4 -2.4 -0.5 -0.0 -2.5 -2.2 -0.9