Hub : Genes

OSBPL6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.097	0.0410	6.0e-03	0.005	NA	0.010	NA	-0.003	1.1e-01	NA	4.4e-02	NA	8.1e-01
2	GTEx	Cells Transformed fibroblasts	0.116	0.0540	9.5e-03	-0.002	NA	0.016	NA	-0.004	5.6e-01	NA	2.2e-02	NA	1.0e+00
3	GTEx	Esophagus Mucosa	0.679	0.0450	0.0e+00	0.510	NA	0.511	NA	0.525	6.6e-39	NA	4.6e-39	NA	1.5e-40
4	GTEx	Esophagus Muscularis	0.105	0.0420	1.8e-03	0.011	NA	0.020	NA	0.021	6.5e-02	NA	2.1e-02	NA	1.8e-02
5	GTEx	Nerve Tibial	0.853	0.0306	1.4e-11	0.133	NA	0.000	NA	0.059	1.2e-09	NA	2.9e-01	NA	5.2e-05
6	GTEx	Skin Not Sun Exposed Suprapubic	0.164	0.0580	1.9e-03	0.056	NA	0.056	NA	0.059	5.1e-04	NA	5.0e-04	NA	3.5e-04
7	GTEx	Skin Sun Exposed Lower leg	0.348	0.0580	5.1e-10	0.218	NA	0.214	NA	0.233	6.7e-18	NA	1.4e-17	NA	3.2e-19
8	TCGA	Prostate Adenocarcinoma	0.150	0.0410	2.2e-08	0.135	0.103	0.131	NA	0.129	5.7e-14	7.4e-11	1.4e-13	NA	2.1e-13

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.2	0.3	0.5	0.2	-0.7	-0.4	0.7	0.4	-0.6	-0.3	-0.5
Bipolar Disorder or Schizophrenia	0.4	0.9	4.5	0.2	-1.1	0.7	2.1	-0.4	0.8	0.7	0.0
Depressed Affect (Nagel 2018)	0.4	0.9	2.1	0.9	1.4	0.5	1.3	1.3	0.5	0.2	0.2
Depression (Nagel 2018)	0.5	0.8	1.9	0.7	0.1	-1.2	0.9	1.1	0.1	-1.4	0.8
Intelligence (Savage-Jansen 2018)	0.4	1.2	4.8	1.2	-0.6	-0.3	0.4	-0.5	-2.2	0.2	-1.6
Neuroticism (Nagel 2018)	0.2	0.4	1.4	0.6	0.8	-0.1	1.2	0.2	0.3	-0.5	0.7
Schizophrenia (2018)	0.7	1.4	4.6	0.1	-0.8	1.3	2.1	-0.8	1.5	1.1	0.3
Schizophrenia vs Biploar Disorder	0.4	0.5	1.0	0.3	-0.6	-0.7	0.7	-0.8	0.0	-0.8	1.0
Worry (Nagel 2018)	0.4	0.8	2.0	0.0	0.7	-1.0	1.2	0.5	-0.1	-1.2	1.4
Alzheimer’s Disease (in mother)	0.8	0.9	2.9	1.1	1.7	0.5	0.8	-0.3	1.1	0.7	0.7
Alzheimer’s Disease (in father)	1.7	1.8	4.8	-0.7	0.7	2.2	1.1	0.6	1.6	2.1	-0.2
Alzheimer’s Disease (including proxy)	1.1	1.6	3.8	0.7	1.0	1.7	1.2	0.3	1.4	2.0	0.9
Crohns Disease (2017)	1.1	2.5	6.3	2.5	-0.4	-1.9	1.8	-0.6	-1.2	-2.1	0.4
Irritable Bowel Disease (IBD)	0.2	0.5	2.5	1.6	0.1	-0.4	0.4	-0.1	-0.4	-0.7	0.3
Ulcerative Colitis (UC)	0.3	0.6	1.8	-0.2	0.5	1.4	-0.7	0.6	0.8	1.1	0.2
Major Depression (MDD)	0.2	0.2	0.4	-0.5	-0.4	-0.6	0.1	0.0	-0.6	-0.6	-0.2
Reaction Time	0.2	0.4	1.0	-0.8	0.3	-0.3	1.0	-0.6	0.8	0.1	0.9
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.4	0.0	0.2	0.1	0.2	-0.4	-0.9	0.2	-1.2
Breast Cancer	0.4	1.0	2.8	-0.6	-0.1	-0.9	0.1	-0.3	-1.7	-0.9	-1.7
Ovarian Cancer	0.6	0.9	2.3	-0.4	1.5	1.2	-0.0	-0.0	0.6	1.4	0.8
Prostate Cancer	2.1	2.9	6.7	-2.6	1.4	1.1	-1.9	1.8	0.1	0.7	-2.5
Age at First Birth	0.3	0.4	1.2	0.8	0.1	-0.3	-0.9	-1.1	0.2	0.1	-0.5
Bipolar Disorder (2011)	0.6	0.6	1.2	-0.7	0.6	1.0	0.7	1.1	0.5	0.6	0.5
Body Mass Index (BMI) (2010)	0.5	0.7	2.6	-1.0	-1.6	0.1	-0.7	0.1	-0.4	1.0	-0.6
Coronary Artery Disease (CAD)	0.4	0.4	2.5	-0.3	-0.0	0.1	-0.8	0.1	0.4	-0.1	1.6
Crohns Disease (2012)	1.1	1.8	4.0	1.5	0.9	-1.9	1.7	0.1	-0.7	-2.0	0.4
Mean Putamen Volume	1.0	1.1	2.0	-0.9	-1.4	1.3	-1.0	1.1	0.4	1.3	0.6
Fasting Glucose	0.2	0.2	0.7	0.1	-0.8	0.3	0.5	0.6	-0.0	0.5	-0.1
HbA1C	1.3	1.4	3.1	1.4	-1.2	-1.8	0.9	-0.3	-1.5	-1.4	0.3
HDL Cholesterol	0.4	0.7	2.9	1.7	0.5	-0.4	0.0	-0.8	-0.5	-1.1	0.7
LDL Cholesterol	0.3	0.5	1.3	0.5	-0.9	1.0	0.0	0.5	-0.2	1.1	0.4
Lupus	0.4	0.7	3.5	1.9	0.8	0.0	0.3	0.0	-0.2	0.0	1.0
Neuroticism (2016)	0.4	0.5	1.5	0.3	-0.1	1.1	0.3	-0.1	1.0	1.2	-0.4
Primary Biliary Cirrhosis	1.3	1.9	3.2	0.7	-0.6	1.8	0.1	1.6	1.6	1.8	1.6
Rheumatoid Arthritis	0.6	0.9	3.5	-1.3	0.7	-0.3	-0.4	-1.9	-0.2	-0.3	-1.0
Schizophrenia (2014)	0.6	1.2	2.5	-0.0	-1.1	1.3	1.6	-1.2	1.2	1.2	0.5
Triglycerides	0.5	0.7	3.0	-1.7	0.1	-0.6	0.1	-0.2	-0.9	-0.4	-1.3
Type 2 Diabetes (T2D) (2012)	2.9	3.3	7.7	-2.8	0.1	1.6	-1.4	0.6	1.9	2.5	2.1
Ulcerative Colitis	0.9	1.4	5.3	-1.0	0.8	2.3	-0.4	-0.1	1.1	1.6	0.1
Blood Eosinophil Count	0.2	1.7	3.6	-1.6	1.9	-1.4	0.2	0.6	-0.6	-1.8	-1.4
Blood Platelet Count	0.2	2.1	5.4	-1.6	-2.3	-1.0	-1.9	0.3	-1.1	-0.6	1.4
Blood Red Count	0.2	1.7	8.5	0.5	2.9	-0.9	0.6	-0.4	0.2	-1.1	1.4
Blood White Count	0.1	0.8	1.8	0.6	0.6	-1.2	1.4	-0.2	0.2	-1.1	0.9
Heel T-Score	0.1	0.7	1.4	0.7	-0.5	1.2	1.1	-1.0	0.5	0.5	-0.7
BMI	0.2	1.3	4.5	-0.7	-0.6	-2.1	-0.4	0.8	-1.1	-1.3	-1.0
Height	0.3	4.9	10.8	3.3	0.7	-1.5	-1.1	0.5	-3.1	-2.5	-3.0
Waist Hip Ratio (WHR)	0.3	1.3	4.5	-0.5	-0.3	-1.5	-1.1	1.1	-2.1	-0.8	-0.5
Systolic Blood Pressure	0.4	1.8	4.5	-2.0	-2.1	-1.4	0.9	1.4	-1.1	-0.4	0.3
Smoking Status	0.8	2.0	6.7	-1.1	1.1	-1.4	2.6	1.0	-0.4	-1.8	-0.2
Allergy or Eczema	0.4	1.1	5.7	0.7	-0.1	0.8	-0.4	-0.0	0.3	1.3	2.4
Cardiovascular Disease	0.5	1.7	5.6	-0.8	-2.0	-1.4	-0.3	0.5	-2.4	-0.6	-0.7
Hypothyroidism (self reported)	1.4	3.3	5.2	-1.8	1.4	2.2	-0.9	1.4	2.2	1.9	2.3
Respiratory disease	0.5	1.2	3.6	0.9	-0.2	-1.2	0.7	0.1	-1.4	-0.8	1.9
Type 2 Diabetes (T2D) (2018)	0.8	1.5	6.1	0.1	-0.8	-1.3	-0.8	-0.6	-2.5	-1.1	-1.4
Lung FEV1/FVC ratio	0.5	2.4	7.4	-1.2	-1.5	2.5	-0.1	-0.2	1.2	2.7	-0.1
Lung FVC	0.4	2.2	6.3	-0.3	1.6	1.2	2.5	-0.8	2.5	0.2	-0.2
Neuroticism	1.1	2.7	6.2	2.4	0.8	-1.1	2.5	2.0	0.3	-1.8	0.9
Chronotype (morning person)	0.3	0.8	1.6	1.0	0.5	-1.2	-0.7	-0.8	-0.9	-1.3	-0.3
Hair Pigment	0.0	1.0	7.0	0.4	-0.0	-0.0	-2.6	0.3	0.4	-0.6	0.7
Tanning	0.1	1.1	3.0	-0.2	0.1	0.8	-0.5	-1.2	1.7	0.6	1.7
Hand grip strength (left)	0.6	1.7	5.1	-1.0	2.3	-1.0	-0.0	0.2	-1.9	-1.4	-0.7
Number of treatments/medications taken	0.5	0.9	1.6	-1.3	-0.6	-1.3	-0.8	0.7	-0.8	-1.2	0.1
Average weekly spirits intake	0.8	1.0	3.6	-1.9	0.9	1.1	-0.4	0.3	0.5	1.3	-0.8
Sensitivity / hurt feelings	1.1	1.9	6.9	-1.0	2.0	-0.6	0.2	2.6	1.5	-0.8	0.4
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.3	-0.5	1.1	-0.0	0.2	1.1	1.1	0.2	0.6
Hearing difficulty/problems: Yes	0.5	0.8	1.9	1.1	-1.3	-0.1	-1.4	0.1	0.9	-0.0	-1.0
Relative age of first facial hair	0.4	0.8	3.1	-0.6	-1.3	-0.0	-1.8	0.3	-1.1	-0.1	0.4
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.4	-1.1	-0.9	1.1	0.1	1.6	0.9	1.0	0.6
Ever used hormone-replacement therapy (HRT)	1.0	1.2	3.6	-0.1	0.6	0.7	-0.6	1.2	1.9	0.5	1.8
Ever had hysterectomy (womb removed)	1.1	1.2	4.1	-0.2	0.6	0.2	2.0	-0.1	1.3	0.2	1.9
Systolic blood pressure, automated reading	0.3	0.8	3.0	-0.7	-1.2	-0.9	1.7	-0.4	0.2	-0.4	0.3
Eye problems/disorders: Diabetes related eye disease	1.6	1.7	8.0	1.3	-1.2	-0.3	0.4	0.8	-1.4	0.5	-2.8
Angina	0.3	0.4	1.1	1.1	-1.0	0.1	0.1	0.3	0.5	0.6	0.7
Medication for hormone replacement therapy	0.4	0.5	1.0	-0.9	0.6	0.8	-1.0	-0.9	0.5	0.6	-0.2
Vitamin and mineral supplements	1.1	1.5	4.8	0.2	1.9	1.2	0.4	-0.0	2.2	0.7	1.1
Supplements: Zinc	0.4	0.5	0.9	-0.6	0.9	-0.5	-0.7	0.7	-0.9	-0.6	0.0
Medication: Co-codamol	0.7	0.8	3.5	-0.0	-0.4	0.5	0.4	-1.9	1.1	1.0	-0.7
Medication: Metformin	1.5	2.1	6.5	0.8	-1.5	-1.7	-0.9	0.3	-2.5	-1.3	-1.4
Diabetes (father)	2.0	2.5	4.4	-1.1	-1.9	-0.5	-1.9	1.8	-2.1	-0.0	-1.9
Diabetes (mother)	1.1	1.4	4.0	-1.1	-0.1	-2.0	-0.7	1.0	-1.3	-1.3	-1.0
Severe depression (siblings)	0.7	0.8	2.3	-0.4	-0.3	-1.3	-0.7	0.5	-1.1	-1.5	-0.1
Pack years adult smoking proportion	1.1	1.7	5.8	2.4	-1.7	-1.3	1.5	-0.2	-0.4	-0.9	0.0
Impedance of leg (right)	0.4	1.9	6.5	0.4	2.5	1.7	-0.6	1.8	0.9	1.2	-0.3
Leg fat-free mass (left)	0.5	2.6	7.1	0.4	-1.6	-2.3	-0.9	-0.5	-2.7	-1.8	-1.2
Trunk fat percentage	0.5	2.2	6.7	0.5	0.0	-2.6	-2.1	0.2	-1.1	-2.2	-0.4
Hand grip strength (right)	0.5	1.4	4.6	0.0	0.8	-1.5	0.9	-0.2	-2.1	-1.3	-1.0
Townsend deprivation index at recruitment	0.7	1.0	2.7	0.7	-0.4	-1.6	-0.0	-0.8	-1.5	-1.4	-0.2
Current tobacco smoking	0.5	0.8	1.6	-0.2	0.1	-0.9	1.2	-1.3	-0.7	-1.3	-0.8
Average weekly fortified wine intake	0.5	0.6	1.4	0.8	0.2	0.6	1.2	-0.9	0.7	1.1	-0.3
Maternal smoking around birth	1.0	1.5	5.0	-0.1	-1.8	-1.5	0.1	0.5	-2.2	-0.9	0.4
Fed-up feelings	0.9	1.6	6.9	0.2	1.9	-0.8	0.6	2.6	-0.1	-1.2	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	4.1	-0.5	-0.3	-0.8	0.7	2.0	0.1	-0.7	0.5
Relative age voice broke	1.0	1.5	4.0	-1.5	1.3	0.3	-2.0	1.8	-0.5	-0.0	-0.3
Taking other prescription medications	0.7	1.0	4.4	-0.5	-1.1	-0.4	-2.1	1.3	0.1	-0.1	0.7
Age when periods started (menarche)	0.1	0.3	0.8	0.3	0.4	0.2	0.5	-0.1	-0.9	0.7	0.7
Bilateral oophorectomy (both ovaries removed)	1.5	1.8	4.7	0.1	1.4	0.0	2.2	-0.3	1.7	-0.4	2.0
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	4.9	-1.1	-0.3	1.1	-2.2	-2.2	0.7	0.7	-0.1
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	3.7	0.5	-1.9	1.1	0.2	-0.4	1.0	1.3	0.2
Qualifications: CSEs or equivalent	1.3	1.7	3.6	-0.9	-1.8	1.0	-1.8	0.4	-1.0	1.9	-0.8
Serious illness, injury or assault to yourself	0.4	0.5	1.2	0.8	-1.1	-1.0	0.7	0.2	-0.3	-0.8	-0.4
High blood pressure	0.4	1.3	4.2	0.6	-2.1	-1.7	0.6	-0.9	-0.8	-0.8	0.4
Hayfever, allergic rhinitis or eczema	0.4	0.9	4.1	1.3	-0.5	0.5	-0.1	0.1	-0.5	0.9	2.0
Multivitamins +/- minerals	1.7	2.2	4.3	-1.4	-2.1	-1.5	-1.4	1.2	-1.9	-1.1	-0.8
Stomach or abdominal pain in last month	0.9	1.1	4.0	1.2	-0.6	1.0	-0.8	2.0	0.5	1.0	0.6
Supplements: Glucosamine	0.4	0.5	1.6	-1.0	0.6	-0.3	0.3	1.3	0.1	-0.5	0.6
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.6	-0.5	-0.6	0.2	-0.5	1.3	0.3	-0.1	-0.4
Medication: Atenolol	2.5	3.1	7.6	0.7	-0.7	-2.0	-1.9	-2.8	-1.2	-1.9	-1.8
Medication: Levothyroxine sodium	0.7	1.2	2.5	-0.8	1.3	1.1	-0.7	1.6	1.3	1.0	0.9
Sitting height	0.8	6.0	14.9	3.7	-1.0	-2.6	-0.8	0.3	-3.9	-3.2	-1.0
Chronic bronchitis/emphysema (father)	0.4	0.5	2.2	-0.5	0.6	0.2	-1.1	-1.5	0.0	-0.1	-0.1
High blood pressure (mother)	1.0	1.3	3.8	-0.9	-1.3	-0.8	-1.1	-0.7	-1.2	-0.7	-1.9
Body mass index (BMI)	0.4	1.7	5.5	0.4	-1.7	-2.3	-1.1	-0.2	-1.1	-1.6	-0.4
Impedance of leg (left)	0.3	1.6	6.2	0.8	2.5	1.4	-0.5	1.4	1.0	1.0	0.3
Leg predicted mass (left)	0.5	2.6	7.2	0.3	-1.6	-2.2	-0.9	-0.6	-2.7	-1.8	-1.2
Trunk fat mass	0.6	2.7	8.2	0.8	-0.5	-2.9	-1.7	0.4	-1.9	-2.3	-0.7
Waist circumference	0.7	2.7	6.2	-0.1	-1.4	-2.5	-2.3	-0.2	-2.0	-1.6	-1.4
Number of incorrect matches in round	0.7	1.2	3.8	-0.9	2.0	0.0	1.0	1.1	0.2	0.0	1.6
Past tobacco smoking	0.6	1.1	2.5	1.4	-0.5	1.2	-1.2	-1.6	0.2	0.9	0.0
Alcohol usually taken with meals	0.6	0.9	3.5	-0.3	-0.1	-0.1	1.6	-0.8	-1.9	-0.4	-0.6
Nervous feelings	0.6	1.2	2.3	-1.3	1.5	0.4	1.4	0.9	1.0	0.3	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.0	-0.5	-0.2	-0.9	-0.0	1.4	0.1	-1.0	-0.8
Hearing difficulty/problems with background noise	1.0	1.6	4.5	0.9	0.8	-1.7	0.3	1.9	-0.0	-2.1	-0.6
Hair/balding pattern: Pattern 2	0.5	0.7	1.7	0.0	-1.2	0.9	-1.3	0.0	-0.0	1.1	0.5
Had menopause	1.1	1.3	3.4	-1.8	0.6	-1.2	-0.0	0.5	1.3	-1.9	0.6
Had other major operations	1.0	1.2	3.9	-0.2	-0.8	1.4	-0.3	-0.5	1.3	0.8	2.0
Forced vital capacity (FVC)	0.2	0.9	3.8	0.1	1.1	1.1	2.0	-0.0	0.8	0.1	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	4.8	-0.4	-1.3	0.4	-1.5	-2.2	0.4	-0.0	-0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.0	-0.5	-0.8	-0.3	-0.2	1.4	0.4	-0.1	0.2
Qualifications: None of the above	0.7	1.6	3.7	1.9	-0.2	-1.6	1.4	-0.6	0.7	-1.6	0.9
Financial difficulties in last 2 years	0.5	0.6	2.4	0.2	0.5	-0.8	-0.6	0.6	0.7	-0.8	1.5
Mouth/teeth dental problems	1.0	1.6	3.0	-1.7	0.4	1.3	-1.7	0.8	1.4	1.1	0.9
Heart attack	1.0	1.2	4.6	-0.9	0.2	-0.4	-2.1	0.1	-1.2	-0.6	-1.6
Allergy	0.3	0.8	2.7	-0.8	1.0	0.1	0.4	0.2	1.6	-0.2	-1.2
Pain all over the body in last month	0.6	0.7	1.6	1.2	0.3	-0.4	0.1	1.1	1.3	0.1	0.9
Diabetes (self-reported)	0.7	1.1	2.7	-0.1	-0.4	-0.9	-1.3	0.5	-1.5	-0.8	-1.6
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.0	-1.0	-0.4	-0.1	-0.8	0.5	-1.0	-0.2	0.9
Medication: Ramipril	3.0	3.9	10.2	-2.9	-0.2	-3.2	0.2	0.3	-0.7	-2.9	1.7
Medication: Simvastatin	1.1	1.6	3.6	0.2	-0.9	-1.4	-0.6	-0.8	-1.7	-1.6	-1.9
Fluid intelligence score	0.5	1.0	3.5	-0.3	-0.2	-0.8	0.1	-0.3	-1.8	-0.7	-1.9
Illnesses of siblings	1.1	1.5	3.3	-0.9	1.8	1.4	-0.6	1.0	1.2	1.1	1.2
Neuroticism score	0.7	1.4	2.8	0.8	1.2	-1.2	1.4	1.7	0.4	-1.5	0.3
Weight	0.7	3.5	8.6	1.3	-1.2	-2.9	-1.6	0.2	-2.5	-2.4	-1.1
Impedance of arm (right)	0.1	0.5	1.7	-0.1	1.3	0.8	-1.2	0.5	0.2	0.5	-0.1
Arm fat percentage (right)	0.3	1.3	4.9	0.1	-0.9	-2.2	-1.5	0.2	-0.7	-1.5	-0.1
Trunk fat-free mass	0.4	2.5	8.2	1.2	-1.5	-2.1	0.2	0.1	-2.9	-1.7	-1.1
Hip circumference	0.3	1.5	3.5	-0.5	-0.9	-1.7	-1.9	-0.3	-1.4	-1.4	-0.8
Time employed in main current job	0.5	0.6	2.2	-0.1	1.5	-0.0	-0.1	-1.4	0.5	0.2	-0.1
Alcohol intake versus 10 years previously	0.2	0.4	0.7	-0.7	0.9	0.1	-0.8	-0.8	-0.7	0.0	-0.1
Father’s age at death	0.3	0.5	2.8	-0.5	0.2	-0.2	-1.7	0.1	0.7	0.0	-0.2
Worrier / anxious feelings	0.2	0.4	0.9	0.4	0.7	-0.7	0.9	0.5	-0.1	-0.7	-0.6
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	7.5	2.7	-0.3	-1.0	0.7	2.3	-0.1	-0.8	1.0
Falls in the last year	0.9	1.2	5.2	-0.7	-0.5	-1.0	-2.3	1.4	-0.4	-0.6	-0.5
Hair/balding pattern: Pattern 3	0.5	0.7	1.4	1.0	1.0	-0.7	-0.6	0.5	-1.2	-0.8	-0.8
Number of live births	0.5	0.7	2.2	-1.5	0.8	0.4	-1.3	-0.2	1.0	0.2	0.4
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	4.7	-0.0	0.7	1.3	2.2	0.0	0.7	0.6	-0.0
Pulse rate	4.6	7.7	38.2	0.6	-6.2	-0.4	-4.2	-0.7	-2.1	-0.3	-0.1
Happiness	0.8	1.0	2.0	-0.0	-1.3	-1.1	-1.1	1.4	-0.5	-1.1	0.4
Noisy workplace	1.3	1.6	8.7	1.2	0.4	-0.4	1.2	3.0	-0.4	-0.7	0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.2	4.9	-2.2	-0.3	0.8	-1.2	0.3	0.4	1.2	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.5	-0.3	-1.6	-0.2	-0.1	0.2	-1.1	-0.0	-1.4
Mouth/teeth dental problems: Dentures	2.7	4.5	17.7	-0.4	-1.2	-2.0	-0.6	-2.1	-4.2	-1.8	-2.1
Asthma	0.1	0.2	0.9	-0.1	-0.3	-0.3	0.2	0.7	-0.9	-0.3	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.3	0.4	-0.1	0.6	-0.7	-0.8	0.7	-0.1	1.2
Medication: Cholesterol lowering	0.5	0.8	2.0	0.1	-1.4	-0.7	-0.2	0.4	-1.3	-0.5	-1.3
Depression (self-reported)	0.7	0.8	2.6	1.6	-0.4	-0.2	1.1	0.1	0.5	0.2	1.5
Medication: Lansoprazole	0.9	1.1	3.8	1.5	-1.1	0.2	1.0	-1.9	-0.4	0.3	-0.1
Prospective memory result	0.6	0.7	3.6	0.5	-1.2	0.4	0.1	-1.9	-0.0	0.3	0.4
Lung cancer (father)	0.9	1.0	2.7	1.6	-1.4	0.5	-1.2	0.1	0.6	1.1	0.5
Illnesses of mother	0.4	0.4	2.2	0.7	1.5	0.6	0.1	0.1	0.4	0.2	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	3.0	0.1	0.7	0.2	1.7	0.1	0.3	-0.8	-0.2
Pulse wave Arterial Stiffness index	0.2	0.3	0.6	-0.5	-0.2	-0.1	-0.8	0.1	-0.6	-0.6	-0.8
Impedance of arm (left)	0.1	0.6	2.8	-0.3	1.7	0.7	-1.1	0.3	0.4	0.2	0.1
Arm fat mass (right)	0.6	2.3	7.3	0.4	-1.3	-2.7	-1.4	-0.1	-1.6	-2.0	-0.7
Trunk predicted mass	0.4	2.5	7.9	1.3	-1.6	-2.0	0.0	0.0	-2.8	-1.7	-1.0
Standing height	0.4	3.5	11.8	2.0	0.8	-1.5	-0.9	1.3	-3.4	-2.0	-1.6
Length of working week for main job	1.6	1.8	4.5	1.3	-1.7	0.1	2.1	1.0	-2.0	0.2	-0.1
Exposure to tobacco smoke at home	0.8	0.8	2.8	1.1	-1.3	-0.5	0.3	0.8	0.4	0.2	1.7
Breastfed as a baby	1.7	2.1	7.1	-2.7	1.0	2.1	-0.4	0.6	1.0	1.4	1.1
Tense / ‘highly strung’	0.6	1.0	3.2	0.5	-0.5	-0.7	1.8	0.9	-0.0	-0.9	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	5.0	1.3	0.3	1.4	-0.2	0.8	2.2	1.4	0.7
Hair/balding pattern: Pattern 4	0.3	0.7	2.5	-0.8	0.1	0.4	0.5	-0.0	1.4	0.1	1.6
Birth weight of first child	0.4	0.7	1.9	0.1	0.0	1.2	-0.2	-1.4	0.5	0.9	-1.0
Peak expiratory flow (PEF)	0.3	0.6	1.3	-0.3	1.1	1.1	1.1	0.8	0.4	0.6	0.4
Pulse wave reflection index	0.9	1.2	6.0	-0.6	2.4	0.8	0.8	0.5	0.3	0.6	-0.9
Ever highly irritable/argumentative for 2 days	1.1	1.3	2.1	0.2	1.4	-1.4	1.4	1.3	0.0	-1.0	1.2
Loud music exposure frequency	1.5	1.6	3.6	0.0	-1.7	-1.4	-1.9	1.4	-1.1	-1.0	0.7
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	9.1	-0.7	-0.4	1.0	-3.0	-1.8	0.4	1.4	-1.2
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	3.0	1.7	-0.8	0.7	1.1	-0.4	1.5	1.1	-0.2
Blood clot in the leg (DVT)	2.8	3.6	9.0	-0.8	-2.8	-2.3	-1.2	-1.0	-3.0	-2.0	-0.0
Medication: Paracetamol	0.6	0.9	2.3	0.7	-0.1	0.5	0.3	1.4	1.3	0.9	1.5
Headache pain in last month	0.4	0.7	3.9	0.6	-0.7	-0.9	-0.1	-0.1	0.0	-0.6	2.0
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	2.1	-0.2	1.5	1.3	0.3	-0.9	1.2	0.8	0.7
Glaucoma (self-reported)	0.2	0.2	0.5	-0.1	-0.5	-0.7	-0.6	0.5	-0.2	-0.3	-0.2
Gout (self-reported)	1.7	2.3	6.5	2.5	-2.1	-1.5	1.4	-0.0	-0.6	-1.3	1.2
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	6.0	-1.3	1.6	1.1	-1.0	2.4	1.3	0.9	0.9
Medication: Amlodipine	0.9	1.3	4.0	-2.0	-1.5	-0.2	-1.5	0.8	0.7	0.2	0.7
Medication: Ventolin 100micrograms inhaler	1.2	1.5	4.5	0.0	1.1	-1.0	-0.7	2.1	-1.6	-0.7	-1.2
Birth weight	0.7	1.6	3.1	-1.3	1.1	1.4	1.1	1.6	0.2	1.8	-1.0
Chronic bronchitis/emphysema (mother)	1.8	2.2	11.2	1.8	-0.4	-0.7	1.4	-0.1	-0.1	-0.4	3.4
High blood pressure (siblings)	0.1	0.1	0.5	-0.4	-0.7	0.0	0.4	-0.0	-0.2	-0.0	-0.2
Forced vital capacity (FVC), Best measure	0.2	0.6	1.8	-0.0	1.3	0.3	1.2	0.8	0.4	-0.9	-0.1
Body fat percentage	0.4	1.6	4.6	0.4	-0.4	-2.1	-2.1	0.6	-0.7	-1.6	-0.3
Leg fat percentage (right)	0.3	1.0	2.9	0.3	-0.2	-1.5	-1.7	1.0	-0.3	-0.9	-0.8
Arm fat-free mass (right)	0.4	2.0	5.3	0.9	-1.1	-2.2	-0.3	0.2	-2.3	-2.0	-0.5
Exposure to tobacco smoke outside home	1.5	2.0	9.1	0.5	-3.0	0.3	-2.0	0.0	-0.3	1.0	1.3
Comparative body size at age 10	0.3	0.8	2.5	-0.5	0.0	-1.2	1.6	-0.7	-0.7	-0.7	0.6
Number of full brothers	0.9	1.2	4.5	0.6	-2.1	-0.8	-1.6	0.2	-0.8	-0.4	-0.8
Worry too long after embarrassment	0.5	0.8	1.6	0.6	0.7	-0.6	0.3	1.0	1.3	-0.9	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.5	1.4	-0.5	0.1	0.5	1.6	0.6	-0.6	1.3
Wheeze or whistling in the chest in last year	1.0	1.8	3.9	1.7	-0.2	-2.0	0.9	-0.4	-1.9	-1.7	0.7
Number of children fathered	1.5	1.7	4.1	-1.7	2.0	0.2	-1.0	0.5	1.7	-0.2	1.7
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.5	7.4	1.3	0.5	-0.6	2.7	2.6	1.3	-0.1	1.6
Age at first live birth	0.4	0.8	4.5	0.8	-0.3	0.5	-0.2	2.1	-0.7	0.4	-0.3
Pulse wave peak to peak time	0.2	0.3	0.5	0.6	0.4	0.1	0.7	-0.1	0.5	0.6	0.7
Health satisfaction	2.5	3.2	6.9	2.2	-2.3	-2.6	-0.0	0.1	-1.4	-2.5	0.8
Shortness of breath walking on level ground	1.5	1.8	3.6	1.4	-0.5	-1.7	1.5	-0.7	-1.9	-1.6	-0.4
Qualifications: College or University degree	0.7	2.3	6.8	-2.6	-0.6	1.4	-0.4	-2.1	0.2	2.0	-0.7
Eye problems/disorders: None of the above	1.2	1.4	5.8	-2.4	1.4	-0.5	-0.1	-0.2	-0.8	-0.9	-1.2
Mouth/teeth dental problems: Loose teeth	1.2	1.4	5.8	0.6	0.4	0.9	1.5	0.7	1.0	0.8	2.4
Emphysema/chronic bronchitis	0.8	0.9	2.8	0.5	0.8	-1.0	-0.8	0.8	-1.7	-0.9	-0.5
Medication for pain relief, constipation, heartburn	0.4	0.7	2.1	-0.3	1.0	0.4	-0.3	-1.3	-0.6	0.2	-1.4
Neck or shoulder pain in last month	1.2	1.7	3.2	1.2	0.3	0.5	1.7	1.5	1.7	0.4	1.8
Medication: Blood pressure	0.5	0.9	3.0	0.2	-1.7	-1.2	-0.0	1.1	-1.0	-0.6	-0.7
Angina (self-reported)	0.3	0.4	1.8	0.9	-1.3	0.1	-0.1	0.0	0.6	0.7	0.5
Migraine (self-reported)	0.3	0.3	2.1	0.0	-0.6	0.0	-0.1	0.1	-0.1	0.3	1.4
Medication: Ibuprofen	0.6	0.7	3.0	0.3	0.4	0.5	0.3	-1.7	0.8	-0.1	1.1
Medication: Allopurinol	1.4	1.9	5.2	1.8	-2.3	-0.4	1.0	0.2	-0.8	-0.2	2.3
Medication: Omeprazole	0.6	0.7	2.0	0.9	0.2	-1.4	-0.7	-0.7	0.5	-0.8	1.0
Medication: Seretide 50 evohaler	0.5	0.6	1.8	-0.0	0.1	0.5	-0.2	1.3	1.0	1.0	-0.8
Mean time to correctly identify matches	0.4	0.8	2.4	-1.3	0.8	0.2	0.9	0.5	1.5	0.2	0.8
Heart disease (mother)	0.5	0.7	2.5	-1.6	-1.5	0.3	-0.1	-0.3	0.1	0.5	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	4.2	-0.5	2.0	1.2	0.3	0.3	1.6	0.9	0.8
Whole body fat mass	0.6	2.5	6.8	0.3	-1.1	-2.6	-2.1	0.4	-1.7	-2.0	-0.9
Leg fat mass (right)	0.5	1.9	4.8	0.5	-1.0	-2.2	-1.7	0.9	-1.4	-1.5	-1.1
Arm predicted mass (right)	0.4	2.2	6.0	0.9	-1.2	-2.2	-0.1	0.2	-2.5	-1.9	-0.8
Pulse rate, automated reading	5.7	18.3	83.5	1.0	-9.1	-1.6	-7.2	-1.6	-2.0	-0.9	0.8
Alcohol intake frequency.	0.4	0.8	2.1	-0.2	-0.3	-0.1	-1.5	-0.8	-1.4	-0.2	-1.3
Comparative height size at age 10	0.2	1.4	2.8	0.9	0.0	-1.2	-0.4	1.2	-1.7	-1.6	-1.4
Number of full sisters	0.4	0.5	1.3	1.2	-0.2	-0.8	-0.7	0.2	-1.0	-0.5	-0.4
Suffer from ‘nerves’	0.4	0.7	2.4	-1.1	0.5	-0.7	0.7	-1.6	-0.1	-0.7	0.4
Overall health rating	0.4	1.0	3.1	1.1	-1.7	-1.4	-0.5	-0.6	-0.2	-0.9	-0.3
Chest pain or discomfort	0.4	0.6	1.3	1.1	0.5	0.3	1.0	-0.2	0.6	0.3	1.1
Had major operations	0.8	0.9	4.8	0.4	0.5	0.2	0.4	-0.5	2.2	0.3	1.2
Age at last live birth	0.7	1.0	7.7	-0.1	0.5	-0.1	-0.1	2.8	-0.1	0.0	0.2
Family relationship satisfaction	1.1	1.3	2.8	0.9	-1.5	-0.8	-1.4	0.5	0.9	-1.0	1.7
Leg pain on walking	0.6	0.7	1.6	0.1	0.5	-1.3	0.3	0.8	0.9	-1.1	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.9	-0.3	0.4	2.0	0.5	0.1	0.2	1.4	-0.2
Commuting to job workplace: Car/motor vehicle	2.0	2.3	5.8	0.1	1.6	0.3	1.2	2.2	1.9	-0.4	2.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.8	-0.5	0.9	0.3	0.4	-0.8	-0.4	0.5	-0.9
Medication: Aspirin	0.4	0.6	1.8	-0.6	-1.4	-0.6	0.3	0.9	0.5	-0.7	0.7
Supplements: Vitamin C	0.2	0.2	0.7	0.4	-0.8	0.0	0.3	0.0	-0.8	0.2	-0.4
Knee pain experienced in last month	1.0	1.5	4.0	0.7	-0.5	-2.0	-1.0	0.3	-1.7	-1.8	-0.4
Hypertension (Self-reported)	0.4	1.1	4.8	0.1	-2.2	-1.5	0.2	-0.8	-0.5	-0.5	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.1	0.9	0.4	0.9	-0.9	-0.1	0.5	1.4	0.4
Illnesses of father: Heart disease	0.7	1.0	4.4	0.6	-0.9	-1.1	2.1	-0.7	0.3	-0.6	0.4
Illnesses of siblings: Diabetes	1.1	1.3	2.6	1.4	-1.6	-1.1	-0.4	0.7	-1.4	-0.5	-1.5
Smoking status: Previous	0.9	1.4	5.9	-0.8	0.7	-1.1	1.4	2.4	0.1	-0.8	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	2.8	0.6	0.1	-0.7	-1.5	1.3	-1.7	-0.8	-0.3
Whole body fat-free mass	0.4	2.6	7.9	1.0	-1.6	-2.2	-0.3	-0.1	-2.8	-1.8	-1.0
Leg fat-free mass (right)	0.5	2.6	7.5	0.8	-1.4	-2.3	-0.6	-0.7	-2.7	-1.9	-0.9
Arm fat percentage (left)	0.4	1.6	6.0	0.0	-0.8	-2.4	-1.7	0.3	-0.8	-1.7	-0.1
Average weekly red wine intake	0.9	1.3	3.2	-1.3	1.0	-0.9	1.2	-1.8	-1.3	-0.8	-0.5
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.5	-0.2	0.3	0.4	-0.7	0.5	0.5	0.3	0.5
Mood swings	0.7	1.3	6.8	-0.3	1.2	0.1	-0.8	2.6	1.0	0.0	0.5
Loneliness, isolation	0.1	0.2	0.9	0.4	0.4	0.3	-0.2	-0.1	0.0	-0.1	-1.0
Long-standing illness, disability or infirmity	0.4	0.6	3.1	0.4	-1.8	0.4	-0.4	0.7	0.1	0.7	-0.3
Ever had bowel cancer screening	1.0	1.2	4.4	0.5	1.1	-0.6	0.3	1.3	0.7	-0.9	2.1
Diabetes diagnosed by doctor	1.1	1.8	4.9	0.1	-0.9	-1.2	-1.6	0.6	-1.9	-1.0	-2.2
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	3.2	-0.4	-0.6	-1.8	0.1	-0.2	-0.7	-1.3	-0.3
Friendships satisfaction	1.2	1.5	3.9	0.7	-2.0	-1.9	-0.5	-0.3	-0.5	-1.9	0.4
Qualifications: nursing, teaching	0.6	1.0	2.0	-1.4	-0.2	1.2	0.1	0.5	1.4	1.4	-0.4
Commuting to job workplace: Walk	1.5	1.6	6.1	-0.7	-0.8	-0.1	-0.0	-2.5	-0.8	0.6	-2.1
Eye problems/disorders: Cataract	1.2	1.4	8.0	2.8	-0.6	0.3	-0.4	-0.5	1.1	0.6	0.9
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.7	1.9	0.3	-0.8	1.4	1.5	1.1	-0.8	-0.0
Medication for cholesterol	0.9	1.3	5.4	1.0	1.0	0.2	2.3	1.2	-0.6	0.0	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	2.4	-1.6	0.2	1.4	-0.4	-0.9	0.8	1.2	-1.3
Back pain experienced in last month	0.7	1.1	3.4	0.9	1.1	-0.4	1.9	1.6	-0.2	-0.5	0.2
Mineral and other dietary supplements	1.2	1.7	3.4	1.6	-0.2	1.1	-1.0	-1.8	1.6	1.6	-0.0
Breast cancer (self-reported)	0.4	0.4	1.9	-1.4	-0.3	1.0	0.5	-0.1	0.3	0.5	0.0
Asthma (self-reported)	0.2	0.3	1.5	-0.1	-0.1	-0.5	0.5	0.6	-1.2	-0.5	0.0
Osteoporosis (self-reported)	0.2	0.2	0.8	0.9	0.6	-0.1	-0.2	-0.0	0.3	-0.6	0.3
Osteoarthritis (self-reported)	0.3	0.3	1.8	-0.3	0.5	-0.6	-1.3	0.0	-0.3	-0.2	0.0
Medication: Aspirin	0.4	0.5	1.8	-0.5	-1.3	-0.5	0.4	0.8	0.2	-0.6	0.4
Medication: Gliclazide	1.8	2.0	6.6	0.6	-1.7	0.4	-1.7	1.6	-0.7	0.2	-2.6
Illnesses of father: None of the above (group 1)	0.6	0.8	2.3	1.5	0.6	-0.5	-1.2	0.0	-0.7	-1.0	0.8
Smoking status: Current	0.5	0.7	1.4	-0.2	0.1	-0.7	1.0	-1.2	-0.7	-1.1	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	5.9	0.6	0.4	0.8	2.4	-0.8	1.8	0.5	1.1
Whole body water mass	0.5	2.7	8.1	1.0	-1.5	-2.3	-0.3	-0.2	-2.8	-1.9	-1.1
Leg predicted mass (right)	0.5	2.5	7.1	0.7	-1.5	-2.2	-0.7	-0.7	-2.7	-1.8	-0.9
Arm fat mass (left)	0.6	2.6	8.5	0.4	-1.4	-2.9	-1.6	0.0	-1.6	-2.2	-0.7
Number of self-reported non-cancer illnesses	0.2	0.4	1.7	0.4	-1.3	-0.1	-0.7	0.2	-0.4	0.1	0.6
Average weekly champagne plus white wine intake	0.6	0.8	2.8	-1.0	1.7	-0.4	-0.3	1.2	0.5	-0.6	0.1
Miserableness	0.5	0.9	3.4	0.2	1.9	0.2	1.6	0.6	-0.1	-0.2	-0.8
Guilty feelings	0.5	0.7	2.0	0.6	0.6	-1.1	1.4	-0.6	-0.3	-1.2	-0.1
Wears glasses or contact lenses	1.1	1.3	2.9	-0.9	-0.5	1.3	0.8	1.2	1.5	1.7	0.3
Ever taken oral contraceptive pill	0.5	0.5	1.7	0.4	-1.3	-0.1	0.4	-0.9	0.2	0.5	1.1
Hearing aid user	2.7	3.1	12.3	1.2	0.9	2.3	0.6	-0.3	3.5	1.9	0.6
Mother’s age at death	0.2	0.2	1.1	-0.2	0.1	0.0	-0.5	0.3	-0.2	0.2	1.0
Financial situation satisfaction	0.5	0.7	2.8	-0.1	-0.8	0.2	-1.2	1.7	0.6	-0.1	0.4
Tinnitus: Yes, now most or all of the time	2.0	2.4	8.0	0.3	2.8	-1.7	0.8	1.8	0.1	-1.9	0.7
Commuting to job workplace: Public transport	2.1	2.5	7.6	-1.3	-1.5	-1.3	-2.0	-0.5	-1.6	-0.5	-2.8
Eye problems/disorders: Glaucoma	0.4	0.5	1.6	-0.6	-1.3	-0.7	-0.8	0.3	-0.6	-0.4	-0.7
Medication: Blood pressure	1.2	2.2	5.0	-0.4	-0.6	-2.1	-0.5	-2.0	-0.1	-1.7	2.2
Pain type(s) experienced in last month: Hip pain	0.4	0.4	1.7	1.0	-0.2	-0.0	-1.3	0.0	0.7	0.2	0.3
Supplements: Fish oil (including cod liver oil)	1.2	1.5	4.7	-2.2	-0.0	-1.0	0.8	2.1	-0.6	-0.9	-0.4
High cholesterol (Self-reported)	0.1	0.3	0.7	-0.4	-0.7	-0.2	-0.2	0.7	-0.8	-0.1	0.2
Medication: Bendroflumethiazide	0.2	0.3	0.9	-0.6	0.7	-0.1	-0.7	-0.5	0.4	-0.3	0.9
Medication: Paracetamol	0.5	0.8	1.7	1.3	-0.2	0.2	0.6	1.0	1.1	0.4	1.3
Medication: Lisinopril	0.9	1.1	2.8	0.6	-1.7	0.8	0.3	-1.2	-0.9	1.2	-1.1
Medication: Atorvastatin	0.5	0.6	1.7	-1.3	1.2	-0.6	-0.9	0.4	-0.6	-0.0	0.6
Illnesses of father: High blood pressure	0.8	0.9	3.8	-1.9	0.3	-0.4	0.2	-0.3	-1.1	-0.2	-1.5
Alcohol drinker status: Never	0.5	0.6	3.2	-0.2	0.6	-0.3	1.8	-0.2	0.0	-0.5	-1.0
Ever smoked	0.7	1.3	3.1	-1.2	0.1	-1.8	1.4	0.4	-0.9	-1.5	-0.6
Basal metabolic rate	0.5	2.9	8.1	1.0	-1.5	-2.5	-0.7	-0.2	-2.8	-2.0	-1.1
Leg fat percentage (left)	0.2	0.9	2.8	0.3	-0.1	-1.5	-1.7	0.8	-0.2	-0.9	-0.3
Arm fat-free mass (left)	0.4	2.2	5.1	1.1	-1.2	-2.2	-0.3	0.1	-2.3	-2.0	-1.0
Number of operations (self-reported)	0.7	1.1	3.4	-0.8	0.1	1.0	-0.6	-1.1	1.8	0.8	1.2
Average weekly beer plus cider intake	0.7	0.9	1.6	1.2	-1.1	-1.2	-1.1	0.1	-1.1	-0.8	-0.5
Irritability	0.2	0.4	1.6	0.3	0.7	-0.0	-0.0	1.3	0.6	-0.7	0.1
Risk taking	0.6	0.9	2.5	0.7	-0.6	-1.1	-0.1	1.3	0.7	-1.6	0.0
Ever had prostate specific antigen (PSA) test	0.9	1.1	4.0	-0.3	1.1	-0.3	-2.0	0.5	1.3	-0.6	0.9
Fractured/broken bones in last 5 years	1.3	1.6	4.4	-1.1	-0.6	-1.2	-2.1	1.4	-0.9	-1.3	-1.0
Age started oral contraceptive pill	1.1	1.4	4.2	-0.1	-0.0	-2.0	1.2	0.5	-1.0	-2.0	0.2
Diastolic blood pressure, automated reading	0.8	2.5	10.6	-0.6	-3.3	-2.0	-0.8	-1.1	-0.7	-1.5	0.4
Ever depressed for a whole week	0.5	0.6	2.4	0.6	-0.9	-0.4	0.2	1.5	-0.5	-0.4	-0.8
Unable to work because of sickness or disability	1.0	1.3	3.5	-0.4	-1.8	0.5	-1.9	1.4	0.8	0.8	-0.1
Commuting to job workplace: Cycle	0.6	0.7	3.0	-0.7	-0.5	0.6	-0.3	-1.7	-0.1	1.2	0.4
Myopia	1.1	1.5	10.8	-0.6	0.3	-0.3	-3.3	0.1	-0.6	0.2	-0.8
Vascular/heart problems diagnosed by doctor	0.3	0.7	2.7	-0.5	1.6	1.2	-0.2	0.8	0.7	0.5	-0.1
Cholesterol lowering medication	0.6	0.9	3.0	-1.5	0.2	-0.7	-1.7	-0.5	-0.9	-0.6	0.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.9	0.4	0.6	-0.7	-0.1	-0.3	0.9	-0.1	0.8
Pain experienced in last month	0.8	1.4	6.4	-1.5	-0.7	0.9	-0.3	-2.5	0.6	0.5	-0.8
Supplements: Calcium	0.4	0.4	1.2	-0.1	1.1	0.6	0.6	0.9	-0.2	0.1	0.8
Basal cell carcinoma (self-reported)	0.3	0.3	1.6	0.1	-0.2	-0.5	0.7	-1.3	-0.4	-0.4	-0.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	4.1	-0.6	0.4	-0.5	-2.0	0.1	-1.3	-0.8	-1.7
Deep venous thrombosis (DVT) (self-reported)	2.5	3.3	8.4	-0.4	-2.6	-2.3	-0.8	-0.6	-2.9	-2.2	0.2
Heart disease (siblings)	1.3	1.6	3.6	1.5	-1.9	-1.6	1.0	-1.4	-1.1	-0.6	-0.3
Alcohol drinker status: Previous	0.9	1.1	3.0	-0.5	-0.8	1.2	-1.7	0.5	-0.4	1.6	0.5
Pack years of smoking	0.8	1.2	3.7	1.9	-1.4	-1.1	1.3	-0.5	0.0	-0.7	0.4
Impedance of whole body	0.2	1.2	5.5	0.2	2.3	1.2	-0.9	0.8	0.8	0.6	0.3
Leg fat mass (left)	0.5	1.8	4.8	0.5	-0.9	-2.2	-1.7	0.7	-1.4	-1.5	-0.8
Arm predicted mass (left)	0.5	2.7	6.2	1.1	-1.4	-2.4	-0.5	-0.0	-2.5	-2.2	-0.9