Best TWAS P=6.59e-13 · Best GWAS P=9.4e-13 conditioned to 1.11e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PML | 0.14 | 0.02 | lasso | 4 | 0.02 | 1.9e-02 | -5.1 | 5.2 | 2.1e-07 | 0.05 | 0.28 | 0.06 | TRUE |
| 2 | GTEx | Testis | LOXL1-AS1 | 0.36 | 0.15 | lasso | 10 | 0.13 | 2.4e-06 | -6.3 | -6.5 | 8.1e-11 | 0.58 | 0.21 | 0.62 | TRUE |
| 3 | GTEx | Thyroid | LOXL1-AS1 | 0.15 | 0.03 | enet | 40 | 0.03 | 2.6e-03 | -6.3 | 7.2 | 6.6e-13 | -0.33 | 0.10 | 0.38 | TRUE |
| 4 | GTEx | Whole Blood | LOXL1-AS1 | 0.10 | 0.00 | enet | 33 | 0.00 | 5.8e-01 | 6.2 | 5.7 | 9.5e-09 | -0.21 | 0.05 | 0.13 | FALSE |