Best TWAS P=3.08e-09 · Best GWAS P=2.71e-09 conditioned to 0.0127
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Vagina | HMG20A | 0.21 | 0.01 | enet | 17 | 0.05 | 0.0231 | 2.6 | 5.9 | 3.1e-09 | -0.71 | 0.05 | 0.56 | TRUE |
2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | HMG20A | 0.22 | 0.18 | lasso | 2 | 0.12 | 0.0011 | -5.5 | 5.4 | 8.3e-08 | -0.96 | 0.01 | 0.76 | FALSE |