Best TWAS P=4.2e-08 · Best GWAS P=3.61e-08 conditioned to 0.315
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PPP3R1 | 0.25 | 0.22 | lasso | 4 | 0.26 | 5.4e-20 | -5.5 | -5.5 | 4.2e-08 | 0.95 | 0 | 1 | TRUE |
| 2 | GTEx | Artery Tibial | RP11-474G23.2 | 0.17 | 0.14 | lasso | 3 | 0.12 | 2.3e-09 | -5.5 | -5.4 | 6.9e-08 | 0.97 | 0 | 1 | FALSE |