Best TWAS P=3.01e-17 · Best GWAS P=3.55e-17 conditioned to 0.00495
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TGFA | 0.11 | 0.10 | enet | 7 | 0.12 | 5.5e-14 | -8.4 | 8.4 | 3.0e-17 | -0.94 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Nerve Tibial | TGFA | 0.09 | 0.05 | lasso | 3 | 0.03 | 6.2e-03 | 6.1 | 6.5 | 1.1e-10 | -0.45 | 0.39 | 0.18 | FALSE |
| 3 | GTEx | Testis | TGFA | 0.62 | 0.62 | enet | 67 | 0.64 | 3.2e-36 | 6.5 | -6.2 | 6.7e-10 | 0.64 | 1.00 | 0.00 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | TGFA | 0.09 | 0.03 | bslmm | 191 | 0.04 | 7.4e-06 | 6.4 | 8.1 | 5.4e-16 | -0.48 | 0.00 | 1.00 | TRUE |