[Hub]/) : Traits : Hand grip strength (right) : ← →

chr2:134,513,621-136,403,272

Best TWAS P=2.86e-12 · Best GWAS P=1.55e-11 conditioned to 0.531

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LOC100129961	0.17	0.14	enet	9	0.14	2.6e-17	-6.7	-7.0	2.9e-12	0.93	0.01	0.99	TRUE
2	CommonMind	Brain Pre-frontal Cortex	TMEM163	0.05	0.02	lasso	7	0.01	5.9e-03	3.8	-5.5	4.6e-08	0.64	0.25	0.26	FALSE
3	GTEx	Artery Aorta	CCNT2	0.12	0.12	lasso	3	0.11	1.9e-06	5.1	5.1	3.0e-07	-0.52	0.60	0.24	FALSE
4	GTEx	Brain Cerebellar Hemisphere	AC016725.4	0.27	0.18	lasso	4	0.24	8.3e-07	5.9	-5.4	7.4e-08	0.63	0.18	0.60	FALSE
5	GTEx	Esophagus Muscularis	TMEM163	0.09	0.05	lasso	6	0.05	4.8e-04	4.5	-5.3	8.6e-08	0.72	0.08	0.90	FALSE
6	GTEx	Nerve Tibial	AC016725.4	0.15	0.06	lasso	6	0.02	8.1e-03	5.9	-5.9	4.5e-09	0.65	0.48	0.48	FALSE
7	GTEx	Prostate	AC016725.4	0.27	0.03	enet	23	0.13	4.6e-04	-6.1	-6.4	1.7e-10	0.78	0.04	0.90	FALSE
8	GTEx	Testis	CCNT2	0.31	0.26	lasso	6	0.26	9.3e-12	6.1	5.8	5.8e-09	-0.60	0.34	0.66	FALSE
9	GTEx	Testis	AC016725.4	0.18	0.09	lasso	6	0.09	6.3e-05	-6.7	6.7	2.0e-11	-0.95	0.02	0.98	FALSE
10	GTEx	Thyroid	CCNT2	0.09	0.10	lasso	2	0.09	1.8e-07	5.9	5.8	6.4e-09	-0.62	0.56	0.43	FALSE
11	GTEx	Whole Blood	TMEM163	0.11	0.06	lasso	7	0.06	5.0e-06	4.5	-5.8	8.2e-09	0.63	0.66	0.29	FALSE
12	NTR	Blood	CCNT2	0.01	0.00	blup	370	0.00	6.7e-02	6.1	7.0	3.4e-12	-0.69	0.15	0.44	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	CCNT2	0.06	0.03	enet	27	0.05	1.6e-06	5.1	5.9	4.6e-09	-0.72	0.28	0.72	FALSE
14	YFS	Blood	CCNT2	0.01	0.01	blup	363	0.01	6.3e-05	5.1	5.5	3.9e-08	-0.70	0.34	0.52	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ACMSD	0.04	0.01	blup	46	0.02	2.2e-03	5.9	6.8	1.4e-11	-0.87	0.02	0.84	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TMEM163	0.33	0.36	enet	18	0.37	4.7e-22	4.7	-5.2	2.3e-07	0.63	0.01	0.98	FALSE