Best TWAS P=1.94e-10 · Best GWAS P=5.79e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | SLFNL1 | 0.30 | 0.17 | lasso | 14 | 0.28 | 5.3e-13 | 6.2 | 6.0 | 1.8e-09 | 0.86 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SLFNL1 | 0.03 | 0.01 | enet | 6 | 0.02 | 5.6e-05 | -3.2 | 5.3 | 1.1e-07 | 0.58 | 0.12 | 0.72 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SCMH1 | 0.03 | 0.03 | lasso | 2 | 0.02 | 6.2e-03 | 6.4 | -6.4 | 1.9e-10 | -0.99 | 0.01 | 0.93 | TRUE |