[Hub]/) : Traits : Hand grip strength (right) :

chr1:149,815,323-151,227,371

Best TWAS P=4.35e-08 · Best GWAS P=5.86e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ADAMTSL4 0.17 0.14 lasso 4 0.10 3.7e-06 5.4 -5.4 6.2e-08 -0.99 0 1.00 FALSE
2 GTEx Artery Aorta RP11-54A4.2 0.12 0.13 lasso 2 0.11 7.7e-07 5.4 -5.4 5.8e-08 -1.00 0 1.00 FALSE
3 GTEx Artery Tibial ADAMTSL4 0.10 0.06 lasso 4 0.08 6.4e-07 5.2 -5.2 2.2e-07 -0.90 0 1.00 FALSE
4 GTEx Artery Tibial RP11-54A4.2 0.10 0.07 lasso 4 0.09 1.3e-07 5.2 -5.2 1.9e-07 -0.86 0 0.99 FALSE
5 GTEx Esophagus Mucosa ECM1 0.14 0.10 lasso 10 0.12 2.2e-08 5.4 -5.3 1.0e-07 -0.94 0 1.00 FALSE
6 GTEx Esophagus Mucosa ADAMTSL4 0.40 0.40 lasso 5 0.41 5.8e-29 5.4 -5.5 4.3e-08 -0.99 0 1.00 TRUE
7 GTEx Esophagus Mucosa RP11-54A4.2 0.35 0.33 enet 15 0.34 1.6e-23 5.4 -5.3 1.1e-07 -0.96 0 1.00 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ADAMTSL4 0.11 0.07 lasso 4 0.07 1.2e-08 5.4 -5.3 1.3e-07 -0.97 0 1.00 FALSE