[Hub]/) : Traits : Hand grip strength (right) : ← →

chr10:103,527,782-105,282,664

Best TWAS P=2.09e-11 · Best GWAS P=2.7e-10 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CYP17A1-AS1 0.05 0.02 enet 10 0.03 2.8e-03 3.4 5.7 1.2e-08 0.00 0.14 0.61 FALSE
2 GTEx Artery Coronary CYP17A1-AS1 0.20 -0.01 enet 21 0.04 2.3e-02 2.1 6.1 1.1e-09 -0.52 0.04 0.44 FALSE
3 GTEx Brain Cerebellum ARL3 0.20 0.09 enet 32 0.07 3.7e-03 4.6 6.3 3.3e-10 -0.36 0.29 0.32 FALSE
4 GTEx Brain Cortex CYP17A1-AS1 0.15 0.13 lasso 7 0.14 1.3e-04 4.6 5.5 3.1e-08 0.00 0.27 0.17 FALSE
5 GTEx Brain Hypothalamus CYP17A1-AS1 0.34 0.10 lasso 10 0.05 2.6e-02 5.7 5.7 1.4e-08 -0.02 0.10 0.36 TRUE
6 GTEx Esophagus Mucosa SUFU 0.08 0.02 enet 18 0.01 4.2e-02 -2.4 -5.2 2.4e-07 0.08 0.70 0.06 FALSE
7 GTEx Liver ACTR1A 0.15 0.00 lasso 10 0.00 4.6e-01 -5.6 -6.7 2.1e-11 0.72 0.05 0.32 TRUE
8 GTEx Liver TMEM180 0.28 0.17 enet 36 0.17 1.7e-05 -3.8 -6.4 1.5e-10 0.37 0.64 0.20 FALSE
9 GTEx Skin Sun Exposed Lower leg ACTR1A 0.08 0.06 enet 10 0.07 2.7e-06 -4.0 5.4 7.4e-08 -0.21 0.91 0.01 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma SFXN2 0.12 0.09 lasso 4 0.10 4.4e-19 5.2 -5.2 2.2e-07 0.08 0.04 0.96 TRUE
11 The Cancer Genome Atlas Esophageal Carcinoma SFXN2 0.26 0.02 blup 48 0.10 4.9e-04 5.2 -5.6 2.3e-08 0.06 0.01 0.73 TRUE
12 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SFXN2 0.20 0.08 blup 48 0.13 9.3e-07 5.2 -5.2 1.8e-07 0.06 0.04 0.95 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma SFXN2 0.15 0.10 enet 9 0.11 2.4e-08 5.1 -5.5 2.9e-08 0.09 0.07 0.93 FALSE