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chr10:103,527,782-105,282,664

Best TWAS P=2.09e-11 · Best GWAS P=2.7e-10 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Liver	ACTR1A	0.15	0.00	lasso	10	0.00	4.6e-01	-5.6	-6.7	2.1e-11	0.72	0.05	0.32	TRUE
5	GTEx	Brain Hypothalamus	CYP17A1-AS1	0.34	0.10	lasso	10	0.05	2.6e-02	5.7	5.7	1.4e-08	-0.02	0.10	0.36	TRUE
11	The Cancer Genome Atlas	Esophageal Carcinoma	SFXN2	0.26	0.02	blup	48	0.10	4.9e-04	5.2	-5.6	2.3e-08	0.06	0.01	0.73	TRUE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	SFXN2	0.12	0.09	lasso	4	0.10	4.4e-19	5.2	-5.2	2.2e-07	0.08	0.04	0.96	TRUE
8	GTEx	Liver	TMEM180	0.28	0.17	enet	36	0.17	1.7e-05	-3.8	-6.4	1.5e-10	0.37	0.64	0.20	FALSE
3	GTEx	Brain Cerebellum	ARL3	0.20	0.09	enet	32	0.07	3.7e-03	4.6	6.3	3.3e-10	-0.36	0.29	0.32	FALSE
2	GTEx	Artery Coronary	CYP17A1-AS1	0.20	-0.01	enet	21	0.04	2.3e-02	2.1	6.1	1.1e-09	-0.52	0.04	0.44	FALSE
1	GTEx	Adipose Subcutaneous	CYP17A1-AS1	0.05	0.02	enet	10	0.03	2.8e-03	3.4	5.7	1.2e-08	0.00	0.14	0.61	FALSE
13	The Cancer Genome Atlas	Stomach Adenocarcinoma	SFXN2	0.15	0.10	enet	9	0.11	2.4e-08	5.1	-5.5	2.9e-08	0.09	0.07	0.93	FALSE
4	GTEx	Brain Cortex	CYP17A1-AS1	0.15	0.13	lasso	7	0.14	1.3e-04	4.6	5.5	3.1e-08	0.00	0.27	0.17	FALSE
9	GTEx	Skin Sun Exposed Lower leg	ACTR1A	0.08	0.06	enet	10	0.07	2.7e-06	-4.0	5.4	7.4e-08	-0.21	0.91	0.01	FALSE
12	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SFXN2	0.20	0.08	blup	48	0.13	9.3e-07	5.2	-5.2	1.8e-07	0.06	0.04	0.95	FALSE
6	GTEx	Esophagus Mucosa	SUFU	0.08	0.02	enet	18	0.01	4.2e-02	-2.4	-5.2	2.4e-07	0.08	0.70	0.06	FALSE