[Hub]/) : Traits : Hand grip strength (right) :

chr11:46,917,983-48,485,877

Best TWAS P=2.43e-09 · Best GWAS P=6.25e-09 conditioned to 0.167

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MTCH2 0.03 0.00 bslmm 299 0.00 1.1e-01 1.5 -5.6 1.8e-08 -0.33 0.08 0.47 FALSE
2 GTEx Brain Cortex C1QTNF4 0.26 0.04 lasso 8 0.02 1.2e-01 5.4 5.5 4.3e-08 0.70 0.04 0.25 FALSE
3 GTEx Cells Transformed fibroblasts FNBP4 0.11 0.05 lasso 8 0.08 1.6e-06 5.5 -5.5 4.8e-08 -0.65 0.06 0.94 FALSE
4 GTEx Esophagus Muscularis C1QTNF4 0.10 0.05 enet 23 0.06 1.4e-04 -4.9 5.4 8.1e-08 0.42 0.21 0.75 FALSE
5 GTEx Heart Atrial Appendage C1QTNF4 0.26 0.14 lasso 9 0.17 3.9e-08 -4.8 5.2 2.2e-07 0.53 0.39 0.60 FALSE
6 GTEx Liver C1QTNF4 0.25 0.14 enet 16 0.20 2.3e-06 -4.8 5.2 2.4e-07 0.76 0.18 0.68 FALSE
7 GTEx Skin Sun Exposed Lower leg C1QTNF4 0.25 0.22 lasso 12 0.23 4.2e-19 -4.8 5.7 1.5e-08 0.58 0.47 0.53 FALSE
8 GTEx Spleen C1QTNF4 0.31 0.28 enet 29 0.34 1.8e-09 -5.2 5.9 4.3e-09 0.58 0.16 0.83 FALSE
9 GTEx Testis C1QTNF4 0.14 0.12 lasso 4 0.11 1.6e-05 5.5 5.3 1.2e-07 0.72 0.05 0.94 FALSE
10 GTEx Whole Blood C1QTNF4 0.09 0.05 lasso 3 0.03 1.4e-03 -5.2 5.2 2.4e-07 0.42 0.21 0.68 FALSE
11 ROSMAP Brain Pre-frontal Cortex FNBP4 0.04 0.04 lasso 3 0.04 8.2e-06 5.5 -6.0 2.4e-09 -0.85 0.05 0.95 TRUE
12 The Cancer Genome Atlas Colon Adenocarcinoma NUP160 0.05 0.05 blup 44 0.05 7.7e-04 5.5 -5.7 1.5e-08 -0.65 0.02 0.82 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma C1QTNF4 0.03 0.02 blup 15 0.02 1.3e-03 -4.8 5.4 8.1e-08 0.59 0.03 0.75 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma NUP160 0.03 0.02 enet 7 0.02 6.3e-03 -5.2 -5.6 1.9e-08 -0.61 0.04 0.57 FALSE