Best TWAS P=1.45e-17 · Best GWAS P=4.28e-17 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | RAD9A | 0.43 | 0.22 | lasso | 6 | 0.23 | 7.1e-19 | -8.4 | -8.2 | 3.2e-16 | 0.97 | 0 | 1.00 | FALSE |
2 | GTEx | Artery Tibial | RAD9A | 0.39 | 0.26 | lasso | 2 | 0.24 | 3.5e-19 | -8.4 | -8.4 | 4.1e-17 | 1.00 | 0 | 1.00 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | RAD9A | 0.24 | 0.16 | lasso | 3 | 0.16 | 3.6e-12 | -8.4 | -6.9 | 3.7e-12 | 0.92 | 0 | 1.00 | FALSE |
4 | GTEx | Colon Transverse | RAD9A | 0.40 | 0.16 | lasso | 8 | 0.16 | 7.2e-08 | -8.4 | -6.7 | 2.2e-11 | 0.88 | 0 | 1.00 | FALSE |
5 | GTEx | Esophagus Muscularis | RAD9A | 0.25 | 0.26 | lasso | 2 | 0.26 | 6.2e-16 | -8.4 | -8.5 | 1.5e-17 | 0.99 | 0 | 1.00 | TRUE |
6 | GTEx | Muscle Skeletal | RAD9A | 0.12 | 0.02 | lasso | 4 | 0.03 | 4.2e-04 | -8.4 | -6.2 | 4.2e-10 | 0.83 | 0 | 0.99 | FALSE |
7 | GTEx | Nerve Tibial | RAD9A | 0.53 | 0.24 | lasso | 10 | 0.23 | 5.6e-16 | -8.4 | -8.2 | 2.7e-16 | 0.99 | 0 | 1.00 | FALSE |
8 | GTEx | Testis | RAD9A | 0.72 | 0.50 | lasso | 4 | 0.49 | 1.1e-24 | -8.4 | -8.3 | 1.1e-16 | 1.00 | 0 | 1.00 | FALSE |
9 | ROSMAP | Brain Pre-frontal Cortex | RAD9A | 0.34 | 0.17 | enet | 21 | 0.20 | 1.1e-25 | -8.4 | -7.5 | 6.3e-14 | 0.89 | 0 | 1.00 | FALSE |
10 | YFS | Blood | RAD9A | 0.08 | 0.02 | lasso | 7 | 0.04 | 5.4e-12 | -8.4 | -5.1 | 2.9e-07 | 0.78 | 0 | 1.00 | FALSE |