Best TWAS P=1.91e-08 · Best GWAS P=1.91e-08 conditioned to 0.000427
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ZNF571 | 0.08 | 0.01 | enet | 14 | 0.02 | 2.1e-02 | -4.3 | 5.6 | 1.9e-08 | 0.44 | 0.14 | 0.43 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | ZNF571 | 0.09 | 0.02 | enet | 10 | 0.01 | 5.7e-02 | 4.2 | 5.4 | 5.2e-08 | 0.48 | 0.09 | 0.26 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Male) | ZNF571 | 0.11 | 0.00 | enet | 8 | 0.01 | 1.9e-01 | 4.8 | 5.5 | 4.0e-08 | 0.55 | 0.04 | 0.25 | FALSE |
| 4 | GTEx | Esophagus Mucosa | ZNF573 | 0.06 | 0.02 | enet | 13 | 0.02 | 2.2e-02 | 4.4 | 5.5 | 3.2e-08 | 0.48 | 0.10 | 0.53 | FALSE |
| 5 | GTEx | Pituitary | ZNF781 | 0.37 | 0.01 | enet | 25 | 0.10 | 2.1e-03 | -4.0 | 5.1 | 2.8e-07 | 0.41 | 0.10 | 0.44 | FALSE |
| 6 | GTEx | Thyroid | ZNF571 | 0.10 | 0.01 | enet | 11 | 0.04 | 2.9e-04 | 4.8 | 5.5 | 4.8e-08 | 0.66 | 0.02 | 0.91 | FALSE |
| 7 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZNF585B | 0.03 | 0.02 | enet | 4 | 0.02 | 5.4e-06 | -3.9 | -5.2 | 2.3e-07 | -0.56 | 0.00 | 0.98 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF607 | 0.04 | 0.03 | enet | 3 | 0.03 | 4.4e-04 | 4.7 | 5.1 | 2.7e-07 | 0.57 | 0.01 | 0.83 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | ZNF573 | 0.11 | 0.05 | enet | 9 | 0.09 | 4.0e-09 | -4.7 | 5.5 | 5.0e-08 | 0.44 | 0.02 | 0.96 | FALSE |