TWAS hub - ZNF573

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0850	0.0270	4.5e-12	0.096	0.119	0.134	0.122	0.138	9.0e-12	2.9e-14	5.9e-16	1.2e-14	1.9e-16
2	GTEx	Adipose Subcutaneous	0.0570	0.0270	6.6e-03	0.046	NA	0.017	NA	0.025	1.2e-04	NA	1.4e-02	NA	3.6e-03
3	GTEx	Cells EBV-transformed lymphocytes	0.1690	0.0720	1.9e-03	0.113	NA	0.099	NA	0.104	1.6e-04	NA	4.1e-04	NA	2.9e-04
4	GTEx	Cells Transformed fibroblasts	0.1140	0.0400	1.4e-05	0.126	NA	0.111	NA	0.118	1.1e-09	NA	1.2e-08	NA	3.7e-09
5	GTEx	Esophagus Mucosa	0.0570	0.0280	6.1e-03	0.019	NA	0.018	NA	0.017	1.9e-02	NA	2.2e-02	NA	2.4e-02
6	GTEx	Thyroid	0.0780	0.0340	4.7e-04	0.016	NA	0.025	NA	0.024	2.1e-02	NA	4.5e-03	NA	5.6e-03
7	YFS	Blood	0.0934	0.0217	0.0e+00	0.147	0.141	0.141	0.142	0.146	8.9e-46	6.7e-44	8.9e-44	3.4e-44	2.6e-45
8	TCGA	Breast Invasive Carcinoma	0.0241	0.0141	3.1e-04	0.019	0.015	0.016	NA	0.018	7.9e-05	4.3e-04	2.4e-04	NA	1.0e-04
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0559	0.0308	5.5e-05	0.049	0.036	0.038	NA	0.045	2.9e-06	5.5e-05	3.4e-05	NA	8.4e-06
10	TCGA	Brain Lower Grade Glioma	0.0481	0.0232	2.3e-05	0.064	0.043	0.049	NA	0.053	9.8e-08	1.0e-05	2.9e-06	NA	1.2e-06
11	TCGA	Prostate Adenocarcinoma	0.0708	0.0359	1.5e-05	0.059	0.050	0.050	NA	0.057	8.9e-07	5.3e-06	5.4e-06	NA	1.3e-06
12	TCGA	Thyroid Carcinoma	0.1050	0.0450	1.4e-08	0.054	0.073	0.091	NA	0.090	5.7e-06	1.4e-07	4.0e-09	NA	4.3e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Hand grip strength (right)	7.5	20.3	30.6	-0.3	4.7	4.0	4.8	5.5	2.7	4.4	4.7	5.1	4.7	5.0	5.5
Hand grip strength (left)	7.4	19.4	28.5	-0.0	4.8	4.2	4.8	5.3	3.4	4.3	4.1	5.2	4.8	4.5	5.0
Peak expiratory flow (PEF)	5.5	12.8	21.3	2.9	4.6	4.1	4.5	4.4	4.0	1.6	1.9	3.1	3.9	2.6	3.8
Multivitamins +/- minerals	4.7	5.9	12.8	0.6	-2.7	-2.2	-2.9	-2.0	-1.5	-2.3	-2.9	-2.2	-2.1	-3.0	-3.6
Pulse wave reflection index	4.7	5.9	9.9	1.0	-1.5	-2.5	-1.4	-3.2	-1.2	-2.5	-2.9	-3.0	-2.5	-3.1	-2.9
Deep venous thrombosis (DVT) (self-reported)	4.7	6.0	9.5	-0.1	-2.2	-3.0	-2.1	-2.6	-1.9	-2.3	-2.5	-3.1	-2.8	-2.8	-2.5
Vitamin and mineral supplements	4.5	6.1	14.7	-0.7	2.6	1.8	2.8	2.3	1.2	2.4	3.1	2.2	2.0	3.2	3.8
Blood clot in the leg (DVT)	4.5	5.8	9.3	0.0	-2.1	-2.8	-1.9	-2.7	-1.8	-2.2	-2.5	-3.0	-2.7	-2.8	-2.7
Medication: Lisinopril	4.1	5.3	9.5	1.3	2.7	2.5	2.6	3.1	2.2	1.4	1.4	2.9	2.8	1.9	1.8
Happiness	4.0	4.9	10.6	0.9	2.0	2.8	1.9	1.9	2.6	1.9	1.1	3.2	3.2	1.6	2.0
Rheumatoid Arthritis	3.2	4.4	7.1	0.6	-2.2	-1.8	-2.2	-1.8	-1.3	-2.2	-2.6	-2.4	-2.0	-2.7	-2.4
Crohns Disease (2017)	3.1	6.9	14.8	0.5	2.8	2.9	2.6	2.4	3.9	2.0	1.9	2.9	2.9	2.3	2.9
Average weekly red wine intake	3.0	4.4	6.8	0.6	2.2	2.1	2.1	2.5	1.9	1.5	1.8	2.6	2.5	2.3	2.3
Crohns Disease (2012)	2.9	4.7	7.7	-0.2	2.5	1.8	2.2	2.5	2.1	1.4	2.3	2.2	1.9	2.8	2.7
Chest pain or discomfort	2.9	4.2	6.9	-0.0	-2.4	-2.5	-2.6	-1.8	-2.2	-1.9	-1.7	-1.8	-2.0	-1.8	-2.6
Shortness of breath walking on level ground	2.8	3.4	7.8	-1.5	-2.2	-1.8	-2.2	-2.8	-2.0	-0.3	-0.7	-2.0	-2.2	-1.3	-1.6
Supplements: Vitamin C	2.8	3.3	5.3	-0.4	-2.2	-1.5	-2.3	-1.9	-1.4	-1.4	-1.7	-2.0	-1.9	-1.9	-2.3
Fractured/broken bones in last 5 years	2.8	3.5	8.1	2.4	-1.5	-0.8	-1.6	-1.5	0.2	-2.8	-2.8	-1.5	-0.8	-2.4	-2.2
Alcohol drinker status: Previous	2.7	3.1	5.3	-1.8	-2.3	-2.3	-2.2	-2.2	-2.0	-0.3	-0.5	-1.6	-1.9	-1.0	-1.5
Age at First Birth	2.4	3.5	8.1	2.2	2.8	1.4	2.3	2.2	1.6	0.6	0.6	2.0	2.3	1.2	1.8
Triglycerides	2.4	3.9	11.9	-3.5	-2.1	-2.3	-2.3	-1.3	-2.5	-0.2	1.1	-1.9	-2.6	0.5	0.2
Medication: Omeprazole	2.4	2.9	5.0	-0.1	-1.9	-2.0	-1.9	-1.2	-1.0	-2.1	-1.4	-2.1	-2.2	-1.4	-1.8
Irritable Bowel Disease (IBD)	2.3	5.5	14.6	1.4	2.8	2.7	2.6	2.0	3.8	1.7	1.0	2.4	2.7	1.3	2.2
Primary Biliary Cirrhosis	2.2	3.1	8.3	-2.3	0.8	0.6	0.7	1.3	0.8	2.3	2.9	1.0	0.4	2.6	2.6
Townsend deprivation index at recruitment	2.2	3.1	8.4	-2.9	0.0	1.3	-0.1	0.6	0.9	2.6	2.7	1.8	0.7	2.3	1.5
Ovarian Cancer	2.1	2.7	7.0	-2.4	1.2	1.0	1.2	0.6	1.2	2.3	2.7	0.9	0.3	2.2	1.7
Systolic Blood Pressure	2.1	10.7	22.5	2.2	3.6	3.2	3.7	3.8	4.7	0.5	1.8	3.6	3.5	3.0	3.4
Serious illness, injury or assault to yourself	2.1	2.6	6.4	-2.5	-2.2	-1.3	-2.1	-2.1	-2.1	0.3	0.5	-1.1	-1.5	-0.1	-1.2
Gout (self-reported)	2.1	2.8	6.3	1.2	-1.7	-0.9	-1.8	-1.1	0.4	-2.5	-2.2	-1.7	-1.5	-1.9	-2.0
Angina (self-reported)	2.1	2.7	5.0	-0.1	-2.2	-1.4	-2.1	-2.2	-0.8	-2.1	-1.4	-1.3	-1.5	-1.2	-1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.1	4.4	9.4	1.8	3.1	1.9	2.9	2.8	1.2	1.0	1.2	1.8	2.3	1.7	2.2
HbA1C	2.0	2.2	5.3	-1.4	1.1	1.0	1.0	1.5	0.6	1.6	2.2	1.5	1.0	2.3	1.6
Forced vital capacity (FVC)	2.0	7.8	18.6	1.1	3.1	2.6	3.1	4.3	2.0	1.7	2.3	2.8	3.0	2.9	3.3
Mean time to correctly identify matches	2.0	3.8	7.2	1.8	-0.7	-2.3	-0.6	-1.4	-1.9	-2.7	-2.7	-2.0	-1.5	-2.4	-2.1
Reaction Time	1.9	3.6	8.0	1.5	-0.9	-2.3	-0.8	-1.2	-2.1	-2.8	-2.4	-2.0	-1.6	-2.0	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.1	13.6	2.1	3.1	2.5	2.9	3.7	1.8	0.8	1.4	2.5	2.9	2.1	2.5
Pulse wave peak to peak time	1.9	2.2	4.9	-0.6	1.3	1.3	1.2	2.2	0.3	1.7	1.7	1.5	1.4	1.8	1.8
Arm fat percentage (left)	1.9	7.8	16.6	-1.1	-2.9	-4.1	-3.0	-2.7	-3.0	-2.5	-2.0	-3.0	-3.3	-2.4	-2.5
Risk taking	1.9	2.8	8.2	-2.9	-2.3	-1.1	-2.3	-2.7	-1.3	0.9	0.3	-0.9	-1.4	-0.5	-1.1
Supplements: Calcium	1.9	2.1	3.6	0.9	1.6	1.9	1.5	1.9	1.8	0.9	0.6	1.5	1.7	0.8	1.2
Prostate Cancer	1.8	2.6	6.9	-2.6	0.2	0.1	0.2	-0.1	1.8	2.2	2.6	0.9	0.3	2.1	1.9
Alcohol usually taken with meals	1.8	2.9	4.6	0.9	2.0	2.1	2.1	2.1	1.8	1.3	0.9	1.6	1.8	1.2	1.8
Forced vital capacity (FVC), Best measure	1.8	6.4	14.4	0.9	2.9	2.4	2.8	3.8	1.9	1.5	2.1	2.6	2.7	2.6	3.0
Comparative body size at age 10	1.8	5.1	15.3	2.3	-1.7	-2.0	-1.8	-0.8	-0.9	-3.9	-3.1	-2.3	-1.7	-2.7	-2.0
Medication: Allopurinol	1.8	2.4	5.2	1.6	-1.3	-1.1	-1.4	-1.1	0.3	-2.1	-2.3	-1.4	-1.1	-2.0	-1.9
Wears glasses or contact lenses	1.8	2.1	4.8	1.6	1.4	2.2	1.5	1.2	1.8	1.0	0.2	1.6	2.2	0.4	0.5
Angina	1.7	2.2	4.4	-0.1	-2.1	-1.2	-2.0	-2.0	-0.6	-2.1	-1.2	-1.1	-1.4	-0.9	-1.6
Trunk fat percentage	1.7	6.7	13.9	-1.6	-2.9	-3.7	-3.0	-2.7	-2.1	-2.0	-1.6	-2.9	-3.3	-2.1	-2.1
Forced expiratory volume in 1-second (FEV1)	1.7	5.6	14.9	2.4	3.0	2.1	2.9	3.9	1.7	0.4	1.2	2.0	2.6	1.9	2.5
Had major operations	1.7	1.9	5.2	1.7	-1.1	-0.1	-1.0	-0.5	1.1	-2.3	-2.1	-1.1	-0.7	-1.7	-1.5
Coronary Artery Disease (CAD)	1.6	1.9	3.8	-0.1	-1.5	-1.5	-1.8	-1.2	-2.0	-1.3	-1.1	-1.4	-1.3	-1.1	-1.5
Waist circumference	1.6	5.7	12.1	-1.9	-3.0	-3.5	-3.0	-2.4	-2.3	-1.6	-1.1	-2.5	-3.0	-1.6	-1.6
Fluid intelligence score	1.6	3.3	9.5	2.3	-1.2	-1.6	-1.3	-0.6	-0.5	-3.1	-2.5	-1.8	-1.2	-2.1	-1.9
Body fat percentage	1.6	6.4	14.0	-1.3	-2.8	-3.7	-2.8	-2.6	-2.4	-2.1	-1.6	-2.8	-3.1	-2.0	-2.0
Number of full brothers	1.6	2.1	3.8	0.7	-1.3	-1.6	-1.4	-0.8	-1.2	-1.4	-1.7	-1.6	-1.3	-1.8	-1.9
Medication: Gliclazide	1.6	1.8	3.5	-0.3	-1.5	-1.2	-1.4	-1.6	-0.5	-0.9	-1.2	-1.6	-1.5	-1.4	-1.9
Alzheimer’s Disease (in father)	1.5	1.6	3.8	0.9	-0.8	-0.7	-0.9	-1.7	-0.6	-1.0	-1.8	-1.0	-0.7	-2.0	-1.8
Medication: Ramipril	1.5	1.9	5.9	2.4	-0.2	0.1	-0.1	-1.0	1.4	-1.6	-2.2	-0.5	0.1	-2.0	-1.7
Arm fat percentage (right)	1.5	6.0	13.5	-0.8	-2.5	-3.7	-2.6	-2.5	-2.6	-2.1	-1.9	-2.6	-2.8	-2.2	-2.2
Comparative height size at age 10	1.5	8.2	20.8	-0.2	1.6	3.4	1.5	3.4	4.6	1.8	2.3	3.6	3.0	2.9	3.2
Number of full sisters	1.5	1.9	2.8	0.5	-1.4	-1.3	-1.6	-1.3	-0.6	-1.6	-1.6	-1.5	-1.2	-1.6	-1.7
Leg pain on walking	1.5	1.9	4.1	1.4	-1.1	-0.7	-1.2	-0.8	-0.5	-1.8	-2.0	-1.3	-0.9	-1.9	-1.9
Ever had bowel cancer screening	1.5	1.7	4.4	-0.9	-1.8	-1.0	-1.7	-2.1	-0.0	-0.2	-0.9	-1.5	-1.4	-1.3	-1.4
Verbal and Numeric Reasoning (VNR)	1.4	3.3	7.7	1.8	-1.3	-2.1	-1.1	-1.1	-0.7	-2.8	-2.3	-2.1	-1.4	-2.1	-1.9
Body Mass Index (BMI) (2010)	1.4	1.9	3.8	-0.9	-1.2	-2.0	-1.3	-1.4	-1.5	-0.9	-0.6	-1.9	-1.9	-0.9	-0.8
Height	1.4	26.7	43.7	-1.1	3.6	4.9	3.5	6.3	5.6	4.1	5.4	6.5	5.2	6.3	6.6
Chronic bronchitis/emphysema (father)	1.4	1.6	3.6	1.2	1.9	1.3	1.7	0.5	1.6	1.0	0.7	1.1	1.4	0.8	1.2
Hair/balding pattern: Pattern 3	1.4	2.0	2.8	0.0	-1.5	-1.4	-1.6	-1.5	-1.3	-1.3	-1.4	-1.7	-1.5	-1.5	-1.6
Number of live births	1.4	1.9	6.2	-0.7	-2.0	-0.5	-2.0	-2.5	-0.0	-0.1	-1.0	-0.9	-1.0	-1.4	-2.0
Medication: Lansoprazole	1.4	1.6	4.1	-1.6	-1.4	-1.1	-1.3	-2.0	-0.5	-0.3	-0.1	-1.5	-1.8	-0.5	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	3.0	-0.5	-1.7	-1.4	-1.7	-1.3	-1.2	-1.0	-0.9	-0.8	-1.1	-1.0	-1.7
Qualifications: nursing, teaching	1.4	2.2	7.2	-1.8	1.0	0.9	1.0	0.2	-0.2	2.7	2.3	1.1	1.0	1.8	1.5
Medication: Co-codamol	1.3	1.5	5.0	-2.2	-0.9	0.0	-1.1	-0.1	-0.6	1.6	2.0	0.5	-0.0	1.7	0.8
Hayfever, allergic rhinitis or eczema	1.3	2.7	5.8	-1.2	1.4	1.5	1.4	1.3	0.9	2.4	2.2	1.6	1.2	1.9	2.1
Health satisfaction	1.3	1.7	3.8	-0.7	-1.8	-1.3	-1.9	-1.0	-1.9	-1.0	-0.7	-0.9	-1.2	-0.7	-1.3
Pack years of smoking	1.3	1.9	3.2	0.5	-1.6	-0.7	-1.7	-1.3	0.3	-1.8	-1.7	-1.4	-1.3	-1.7	-1.6
Lupus	1.2	1.8	5.6	1.3	-0.9	-0.2	-0.8	-1.0	0.3	-2.3	-2.4	-0.5	-0.3	-1.8	-1.7
Waist Hip Ratio (WHR)	1.2	5.5	13.8	-2.9	-2.9	-2.3	-2.9	-3.7	-1.0	-0.2	-0.4	-2.5	-2.9	-1.4	-1.9
Systolic blood pressure, automated reading	1.2	3.6	7.5	1.5	2.3	1.4	2.3	2.2	2.7	0.1	0.9	2.1	2.0	1.6	1.9
Pack years adult smoking proportion	1.2	1.8	3.2	0.5	-1.7	-0.8	-1.7	-1.2	0.1	-1.8	-1.6	-1.3	-1.2	-1.5	-1.4
Nervous feelings	1.2	2.3	4.2	0.3	1.5	2.0	1.3	1.8	0.8	1.7	1.1	2.1	2.0	1.2	1.4
Pulse wave Arterial Stiffness index	1.2	1.4	2.9	0.6	-1.1	-0.9	-1.0	-1.7	0.2	-1.5	-1.4	-1.1	-1.0	-1.4	-1.4
Irritability	1.2	2.0	9.4	-0.3	0.4	1.4	0.5	1.6	3.1	1.0	1.0	1.7	1.1	1.2	1.6
Bipolar Disorder (2011)	1.1	1.1	3.5	-1.2	0.7	-0.3	0.6	0.6	-0.4	1.4	1.9	0.7	0.4	1.7	1.1
Fasting Glucose	1.1	1.3	2.5	-0.0	1.1	-0.4	0.8	1.5	-0.6	1.4	1.4	1.5	1.3	1.1	1.6
Lung FEV1/FVC ratio	1.1	5.4	18.1	4.2	0.1	-1.9	0.1	-0.3	-1.7	-4.2	-3.0	-2.0	-1.0	-2.1	-1.9
Fed-up feelings	1.1	2.0	7.6	-1.6	-2.5	-1.3	-2.8	-1.0	-0.9	-0.8	-0.5	-0.5	-1.2	-0.6	-1.0
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	4.2	1.6	0.2	-1.0	0.3	1.3	-0.7	-2.1	-1.0	-1.2	-0.9	-0.6	0.2
Medication: Levothyroxine sodium	1.1	1.8	5.4	1.6	-0.5	-0.1	-0.4	-0.8	0.4	-1.7	-2.3	-1.1	-0.6	-2.1	-1.8
Heart attack	1.1	1.4	4.3	0.5	-1.0	-0.8	-0.9	-0.7	-0.8	-2.1	-1.1	-1.6	-1.5	-0.9	-1.1
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.9	4.8	-0.6	-2.1	-1.8	-2.2	-0.8	-1.6	-1.3	-0.8	-0.9	-1.2	-0.8	-1.1
High blood pressure (siblings)	1.1	1.5	4.8	-0.0	1.2	0.8	0.9	2.2	0.6	0.5	1.1	1.6	1.3	1.4	1.7
Emphysema/chronic bronchitis	1.1	1.2	3.4	-0.9	-1.7	-1.1	-1.8	-1.1	-0.7	-0.8	-0.3	-1.1	-1.3	-0.5	-0.7
Overall health rating	1.1	2.4	8.7	1.1	-1.6	-1.2	-1.6	-0.4	-0.3	-3.0	-1.7	-1.6	-1.6	-1.2	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	2.6	-0.9	-1.6	-1.3	-1.5	-0.5	-0.6	-0.9	-0.8	-1.2	-1.5	-1.0	-1.4
Long-standing illness, disability or infirmity	1.1	1.7	3.9	0.4	-1.9	-0.8	-2.0	-1.0	0.1	-2.0	-1.3	-1.0	-1.0	-1.0	-1.6
Illnesses of father: None of the above (group 1)	1.1	1.3	3.9	-2.0	-0.1	0.1	0.2	0.9	-1.2	1.9	1.6	0.8	0.4	1.3	0.9
Allergy or Eczema	1.0	2.7	8.2	-0.9	1.6	1.6	1.6	1.1	1.1	2.9	1.9	1.3	1.3	1.4	2.0
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	5.5	0.2	1.0	1.0	1.0	0.4	2.3	1.0	0.7	1.2	1.2	0.7	0.8
Prospective memory result	1.0	1.2	1.8	-0.2	-0.8	-1.2	-0.9	-1.3	-1.3	-1.4	-0.9	-1.1	-1.3	-0.8	-1.3
Hair/balding pattern: Pattern 4	1.0	2.4	4.6	1.6	2.0	1.9	2.0	1.5	1.0	0.9	0.4	1.8	2.1	0.8	1.1
Knee pain experienced in last month	1.0	1.5	4.2	-2.0	-1.4	-1.5	-1.6	-0.9	-1.5	0.2	0.6	-1.1	-1.6	0.2	-0.5
Hypertension (Self-reported)	1.0	2.8	10.1	3.0	1.3	1.4	1.2	1.5	3.2	-1.6	-1.4	1.0	1.3	-0.5	-0.0
Loneliness, isolation	1.0	1.3	2.9	-1.2	-1.6	-1.5	-1.7	-1.1	-0.2	-1.2	-0.3	-1.0	-1.5	-0.4	-0.7
Medication: Aspirin	1.0	1.3	3.4	0.2	-1.4	-0.9	-1.3	-0.7	-0.1	-1.9	-1.2	-1.0	-1.2	-1.0	-1.3
Illnesses of father: High blood pressure	1.0	1.2	5.6	1.8	0.4	1.2	0.3	0.8	2.4	-0.9	-1.1	0.8	1.0	-0.5	-0.0
Ever had prostate specific antigen (PSA) test	1.0	1.1	4.7	-1.3	-1.4	-0.5	-1.5	-2.2	0.2	-0.0	-0.4	-0.4	-0.7	-0.6	-1.3
Major Depression (MDD)	0.9	1.1	2.8	-1.5	-1.7	-0.8	-1.7	-1.1	-0.7	0.1	-0.3	-0.8	-1.1	-0.7	-0.6
Ever had hysterectomy (womb removed)	0.9	1.1	2.6	-0.0	0.7	1.4	0.7	0.7	1.3	1.4	0.6	1.6	1.5	0.6	0.4
Medication for hormone replacement therapy	0.9	1.0	2.9	-1.6	-1.3	0.3	-1.4	-1.7	-0.1	1.3	0.0	-0.0	-0.3	-0.6	-1.1
Illnesses of mother	0.9	1.1	5.0	-1.7	-0.9	-1.2	-0.9	-2.2	-0.6	0.5	0.3	-0.7	-1.0	-0.2	-0.6
Standing height	0.9	9.4	17.9	0.1	2.1	3.5	2.0	3.9	4.2	2.1	2.5	3.8	3.4	3.1	3.6
Number of children fathered	0.9	1.0	2.2	-0.7	-1.2	-1.1	-1.2	-1.5	-1.1	-0.5	-0.4	-0.5	-0.9	-0.5	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.9	-0.4	0.9	1.6	0.9	0.3	1.7	1.5	1.1	0.5	0.8	0.9	0.9
Illnesses of siblings: Diabetes	0.9	1.1	3.0	-0.7	0.7	0.6	0.7	1.5	0.3	1.1	1.7	0.9	0.6	1.7	1.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.4	-0.5	-1.2	-1.8	-1.0	-0.5	-1.6	-1.0	-0.6	-1.0	-1.2	-0.7	-0.5
Vascular/heart problems diagnosed by doctor	0.9	2.6	9.3	-2.9	-0.6	-1.4	-0.7	-1.3	-3.0	2.2	1.5	-0.7	-0.9	0.5	0.5
Heart attack/myocardial infarction (self-reported)	0.9	1.1	4.3	0.5	-0.8	-0.7	-0.8	-0.6	-0.5	-2.1	-0.9	-1.5	-1.4	-0.7	-0.9
Mean Putamen Volume	0.8	0.9	2.7	0.4	-0.2	-1.5	-0.3	1.5	-1.4	-1.6	0.3	-0.7	-0.7	0.7	0.1
HDL Cholesterol	0.8	1.3	4.3	-0.2	0.9	1.3	0.7	0.6	2.1	0.9	1.2	0.9	0.8	1.3	1.4
Hearing difficulty/problems: Yes	0.8	1.2	2.3	0.0	-0.9	-0.9	-1.0	-1.5	-0.6	-1.0	-1.1	-1.2	-1.2	-1.2	-1.5
High blood pressure	0.8	2.2	7.7	2.8	0.7	1.0	0.7	1.0	2.8	-1.9	-1.7	0.5	0.7	-0.8	-0.6
High blood pressure (mother)	0.8	1.2	5.4	2.3	-0.1	0.2	-0.0	0.9	0.8	-1.8	-1.6	0.0	0.4	-1.0	-0.6
Trunk fat mass	0.8	3.2	8.6	-1.0	-2.2	-2.9	-2.2	-1.4	-1.5	-1.7	-1.1	-1.8	-2.2	-1.3	-1.2
Financial difficulties in last 2 years	0.8	1.1	2.9	-1.6	-1.5	-1.0	-1.7	-1.2	-0.8	-0.3	0.4	-0.6	-1.2	0.3	-0.5
Trunk fat-free mass	0.8	4.6	12.3	1.1	1.6	1.8	1.6	3.5	1.1	1.0	1.4	3.2	2.9	2.1	2.5
Falls in the last year	0.8	1.0	2.9	-0.1	-1.2	-0.8	-1.3	-1.1	-1.7	-0.7	-0.7	-0.7	-0.6	-0.8	-1.4
Mouth/teeth dental problems: Dentures	0.8	1.4	3.7	-0.8	-1.7	-1.2	-1.9	-1.3	-0.9	-0.4	-0.6	-1.0	-1.2	-0.8	-1.4
Impedance of arm (left)	0.8	3.8	11.0	-1.8	-2.0	-1.5	-2.0	-3.3	0.6	-0.5	-0.9	-2.7	-2.8	-1.5	-1.6
Wheeze or whistling in the chest in last year	0.8	1.4	3.9	-0.8	-1.7	-0.7	-1.7	-2.0	-0.7	-0.2	-0.7	-0.7	-1.0	-1.0	-1.7
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.2	1.2	1.5	0.8	1.5	0.7	0.7	0.8	-0.2	1.0	1.3	-0.1	0.6
Medication: Aspirin	0.8	1.0	2.3	-0.2	-1.2	-0.9	-1.1	-0.9	-0.0	-1.5	-0.8	-1.1	-1.3	-0.7	-1.1
Diabetes diagnosed by doctor	0.8	1.3	2.7	-0.5	-1.6	-0.4	-1.5	-1.3	-0.0	-0.9	-1.0	-1.0	-1.1	-1.2	-1.6
Hearing aid user	0.8	0.9	2.8	0.8	0.7	1.7	0.8	0.1	1.6	0.5	-0.3	1.3	1.4	-0.0	-0.0
Myopia	0.8	1.2	2.4	-0.8	1.1	1.1	1.0	1.5	0.4	1.0	1.6	0.7	0.5	1.5	1.3
Blood Eosinophil Count	0.7	5.1	13.4	-0.8	1.5	1.2	1.6	3.5	1.2	1.8	2.7	2.2	1.7	3.0	3.7
Cardiovascular Disease	0.7	2.2	7.6	2.5	1.1	1.1	1.0	1.7	2.8	-1.9	-0.7	0.8	0.9	0.3	0.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.8	0.2	-1.2	-0.9	-1.2	-1.3	0.3	-0.9	-0.8	-0.9	-0.8	-0.8	-1.4
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.3	0.8	1.0	1.4	0.8	0.7	1.5	0.7	-0.0	1.3	1.4	0.1	0.4
Average weekly fortified wine intake	0.7	0.9	3.5	-1.9	-0.5	-0.7	-0.5	-1.2	-0.5	1.2	1.2	-0.3	-0.7	0.7	0.2
Body mass index (BMI)	0.7	2.8	7.6	-0.4	-1.7	-2.8	-1.8	-1.0	-2.7	-1.6	-1.1	-1.3	-1.6	-1.2	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	4.4	-1.5	0.7	0.7	0.7	0.6	-0.3	1.9	2.1	0.9	0.6	1.8	1.6
Trunk predicted mass	0.7	4.2	11.6	1.0	1.5	1.7	1.5	3.4	1.0	0.8	1.4	3.1	2.8	2.0	2.3
Length of working week for main job	0.7	0.8	1.5	-0.4	-1.1	-0.8	-1.1	-1.2	-0.5	-0.8	-0.8	-1.1	-1.0	-0.9	-0.6
Breastfed as a baby	0.7	0.8	4.0	-0.6	-0.5	-1.3	-0.3	-1.0	-2.0	0.2	-0.4	-0.7	-0.7	-0.7	-1.0
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	4.0	1.5	-0.4	0.5	-0.4	-0.6	1.1	-1.1	-2.0	-0.6	-0.1	-1.9	-1.4
Leg fat percentage (right)	0.7	2.7	7.2	-0.9	-1.8	-2.7	-1.8	-1.7	-2.0	-1.4	-0.8	-1.5	-1.8	-1.0	-1.2
Exposure to tobacco smoke outside home	0.7	0.9	4.0	-0.1	-0.3	-1.6	-0.2	-0.8	-2.0	-0.4	-0.3	-1.3	-1.0	-0.6	-0.5
Medication for pain relief, constipation, heartburn	0.7	1.3	3.3	-1.2	1.0	0.5	1.1	0.7	0.1	1.8	1.4	0.9	0.7	1.1	1.8
Medication: Blood pressure	0.7	1.2	5.7	2.4	0.7	0.5	0.7	0.1	1.5	-1.4	-1.4	0.0	0.5	-0.9	-0.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.2	-0.2	-0.7	-1.5	-0.8	-0.7	-0.9	-1.0	-0.2	-1.3	-1.3	-0.2	-0.7
Back pain experienced in last month	0.7	1.0	2.9	-0.7	-1.5	-0.6	-1.7	-1.1	-0.9	-0.7	-0.5	-1.0	-1.0	-0.6	-1.2
Mineral and other dietary supplements	0.7	0.9	2.1	0.5	1.1	0.7	1.3	0.8	1.5	0.0	0.6	0.9	0.8	1.0	1.3
Arm fat mass (left)	0.7	2.7	8.0	-0.9	-1.8	-2.8	-1.9	-1.0	-2.2	-1.5	-0.9	-1.5	-1.9	-1.0	-1.0
Number of self-reported non-cancer illnesses	0.7	1.2	3.0	0.5	-1.5	-0.4	-1.6	-0.3	0.7	-1.7	-1.3	-0.8	-0.9	-1.0	-1.5
Ever taken oral contraceptive pill	0.7	0.8	2.0	-0.5	0.6	1.2	0.6	0.7	0.9	1.4	1.2	0.7	0.8	1.1	0.6
Intelligence (Savage-Jansen 2018)	0.6	1.7	5.1	2.1	-0.8	-1.4	-0.6	0.1	-0.5	-2.3	-1.7	-1.1	-0.5	-1.2	-1.3
Blood Platelet Count	0.6	7.2	45.6	1.1	-2.2	-2.5	-2.2	-1.5	-6.8	-2.9	-1.6	-1.5	-1.3	-1.1	-2.2
Hypothyroidism (self reported)	0.6	1.5	4.4	1.6	-0.7	0.7	-0.7	-0.5	1.2	-1.1	-2.1	-0.6	-0.1	-1.9	-1.6
Current tobacco smoking	0.6	1.0	3.4	-1.9	-1.6	-0.2	-1.6	-1.2	-0.6	0.4	0.7	-0.1	-0.6	0.3	-0.6
Sitting height	0.6	4.0	17.3	0.6	0.8	2.6	0.6	2.1	4.2	0.9	0.8	2.6	2.3	1.3	1.8
Number of incorrect matches in round	0.6	1.0	3.9	-0.0	0.9	1.4	1.0	2.0	0.6	1.0	0.5	0.6	0.6	0.4	1.0
Hair/balding pattern: Pattern 2	0.6	0.7	3.1	1.8	0.6	0.9	0.7	0.4	1.3	-0.8	-0.8	0.4	0.7	-0.4	-0.0
Alcohol intake versus 10 years previously	0.6	0.8	4.5	2.1	0.9	0.6	0.9	1.0	0.5	-0.8	-0.9	-0.0	0.5	-0.5	-0.2
Loud music exposure frequency	0.6	0.7	1.6	1.1	1.2	1.0	1.2	1.1	0.4	-0.2	0.2	0.7	0.8	0.6	0.5
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	4.1	-1.8	0.2	-0.2	0.1	0.1	-1.2	2.0	1.3	0.3	0.1	0.6	0.7
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.6	0.1	-1.1	0.1	-1.2	-1.2	0.0	-0.6	-1.1	-0.6	-0.4	-1.1	-1.2
Migraine (self-reported)	0.6	0.8	1.7	-0.8	-0.0	1.2	-0.1	1.3	0.1	1.0	1.0	1.0	0.7	1.0	0.8
Heart disease (mother)	0.6	0.7	1.8	0.1	1.1	1.0	1.3	0.9	0.3	0.7	0.7	0.5	0.6	0.7	1.0
Whole body fat mass	0.6	2.4	7.0	-0.9	-1.8	-2.6	-1.9	-1.0	-1.7	-1.6	-0.8	-1.5	-1.9	-0.9	-0.9
Commuting to job workplace: Walk	0.6	0.6	2.2	0.9	0.6	0.9	0.6	0.8	1.5	0.0	-0.3	0.9	1.0	-0.1	0.4
Osteoporosis (self-reported)	0.6	0.8	2.5	-0.6	-0.0	0.8	-0.1	0.7	1.6	0.8	1.2	0.8	0.5	1.2	1.1
Smoking status: Current	0.6	0.9	3.6	-1.9	-1.5	0.0	-1.5	-1.2	-0.5	0.6	0.7	0.1	-0.5	0.3	-0.6
Mother’s age at death	0.6	0.8	2.2	0.1	-0.5	-0.9	-0.6	-1.1	-0.7	-1.0	-0.7	-1.5	-1.2	-0.8	-0.8
Supplements: Fish oil (including cod liver oil)	0.6	0.7	4.1	-0.4	-0.6	-1.0	-0.7	-0.3	-2.0	-0.3	-0.2	-0.9	-0.9	-0.5	-0.8
Medication: Atorvastatin	0.6	0.8	3.1	-0.8	-1.7	-0.4	-1.8	-0.2	-0.2	-1.0	0.3	-0.1	-0.8	0.5	-0.4
Leg fat percentage (left)	0.6	2.3	6.4	-0.7	-1.6	-2.5	-1.7	-1.4	-1.7	-1.6	-0.8	-1.4	-1.8	-0.9	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.7	-0.3	-1.0	-0.9	-0.9	-0.7	-0.2	-1.0	-0.5	-1.2	-1.3	-0.5	-1.0
Bipolar Disorder or Schizophrenia	0.5	1.2	3.2	-1.4	0.9	-0.1	1.0	-0.5	0.5	1.8	1.7	1.0	0.6	1.4	0.8
Schizophrenia (2018)	0.5	1.0	2.0	-0.8	1.3	0.5	1.4	-0.1	0.5	1.4	1.3	0.9	0.7	1.1	0.9
Alzheimer’s Disease (in mother)	0.5	0.5	1.3	-0.6	-0.0	1.1	-0.2	0.3	0.8	1.0	0.9	1.1	0.7	0.9	0.1
Ulcerative Colitis (UC)	0.5	0.8	2.2	1.3	1.3	0.9	1.2	0.5	1.5	0.5	-0.3	0.6	1.1	-0.2	0.6
Schizophrenia (2014)	0.5	1.0	2.6	-1.4	0.7	0.5	0.9	-0.6	0.7	1.6	1.5	1.0	0.6	1.1	0.6
Diabetes (mother)	0.5	0.7	1.7	-0.7	-0.0	0.4	-0.0	1.3	0.3	0.6	1.1	1.2	0.6	1.2	0.7
Relative age voice broke	0.5	0.7	3.5	-1.4	-0.2	-0.9	-0.1	-0.8	-1.9	0.8	0.5	-0.5	-0.7	-0.0	-0.2
Taking other prescription medications	0.5	0.8	3.3	0.8	-0.8	-0.3	-1.0	0.3	0.9	-1.8	-0.9	-0.8	-0.8	-0.5	-0.5
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.2	0.5	-0.5	-0.8	-0.5	-0.7	0.3	-0.6	-1.0	-1.1	-0.9	-1.1	-0.8
Supplements: Glucosamine	0.5	0.6	2.2	0.7	-0.2	0.5	-0.5	-0.4	-0.6	0.4	-1.1	-0.2	0.2	-1.4	-1.5
Impedance of arm (right)	0.5	2.3	8.0	-1.2	-1.4	-1.0	-1.4	-2.8	1.0	-0.2	-0.9	-2.1	-2.0	-1.4	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.8	1.3	0.8	-0.0	0.8	1.2	0.6	-0.8	-0.1	0.2	0.4	0.4	0.5
Arm fat mass (right)	0.5	2.0	6.2	-0.6	-1.6	-2.5	-1.6	-0.9	-1.9	-1.3	-1.0	-1.2	-1.5	-1.1	-1.0
Birth weight of first child	0.5	0.9	2.1	0.0	0.6	0.3	0.6	1.4	0.2	1.4	0.6	1.3	1.4	0.5	1.2
Medication: Paracetamol	0.5	0.8	2.3	1.1	0.6	1.5	0.5	0.5	1.4	0.5	0.2	1.0	1.3	0.4	0.2
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.4	-0.6	-1.2	-0.1	-1.2	-1.1	0.2	-0.1	-0.6	-0.6	-0.7	-0.9	-1.1
Arm fat-free mass (right)	0.5	2.4	9.0	0.5	1.1	0.8	1.0	3.0	0.4	0.3	1.2	2.2	1.8	1.8	1.9
Age at first live birth	0.5	0.9	4.2	1.1	1.9	-0.1	2.0	0.6	0.0	0.2	0.1	-0.2	0.3	0.2	0.8
Qualifications: College or University degree	0.5	1.6	4.5	0.4	0.8	0.8	0.8	2.1	1.6	0.5	1.0	1.5	1.5	1.3	1.5
Leg fat mass (right)	0.5	1.9	6.2	-0.4	-1.5	-2.5	-1.5	-0.7	-1.8	-1.7	-0.8	-1.2	-1.5	-0.8	-0.9
Arm predicted mass (right)	0.5	2.5	9.1	0.7	1.1	1.0	1.0	3.0	0.4	0.4	1.1	2.3	2.0	1.7	1.8
Alcohol intake frequency.	0.5	1.1	3.9	-2.0	-1.3	-1.1	-1.4	0.3	-1.5	0.5	0.9	-0.4	-0.9	0.6	0.5
Family relationship satisfaction	0.5	0.6	2.5	-1.6	-0.8	-0.1	-0.8	-1.1	-0.1	1.0	0.5	0.7	0.3	0.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	2.7	-0.2	0.5	1.3	0.6	1.3	1.6	0.6	1.0	1.1	1.0	1.3	1.3
Whole body fat-free mass	0.5	2.8	9.6	1.0	1.2	1.1	1.2	3.1	0.7	0.3	0.9	2.4	2.2	1.6	2.0
Mood swings	0.5	1.0	3.0	0.0	0.3	1.1	0.2	1.7	1.4	-0.2	0.6	1.3	0.8	1.2	1.0
Whole body water mass	0.5	3.0	10.1	1.1	1.3	1.2	1.3	3.2	0.7	0.4	1.0	2.5	2.3	1.6	2.1
Medication: Paracetamol	0.5	0.8	2.9	0.9	0.5	1.4	0.5	0.5	1.7	0.6	0.3	1.0	1.2	0.4	0.2
Average weekly beer plus cider intake	0.5	0.7	1.4	-0.3	-0.6	-1.2	-0.5	-0.4	-1.0	-0.9	-0.4	-1.2	-1.2	-0.5	-0.8
Ever depressed for a whole week	0.5	0.7	1.7	0.8	-0.6	0.3	-0.7	-1.3	0.3	-0.4	-1.2	0.2	0.4	-1.1	-1.3
Depressed Affect (Nagel 2018)	0.4	0.9	3.2	-1.3	-1.7	-0.8	-1.8	-0.6	-0.3	-0.7	-0.3	-0.3	-0.9	-0.2	-0.6
Heel T-Score	0.4	3.3	6.1	0.7	2.0	2.2	2.0	1.5	1.8	1.2	1.2	2.5	2.4	1.6	1.8
BMI	0.4	2.4	9.5	-0.2	-1.3	-2.8	-1.3	0.4	-3.1	-1.9	-0.7	-1.2	-1.5	-0.6	-0.7
Number of treatments/medications taken	0.4	0.7	3.3	0.9	-0.4	0.6	-0.6	0.5	1.8	-1.2	-0.8	-0.3	-0.3	-0.4	-0.5
Maternal smoking around birth	0.4	0.6	2.3	-1.0	-1.1	0.2	-1.2	-1.5	0.3	0.8	0.0	-0.2	-0.3	-0.4	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.8	-1.4	0.3	0.4	0.4	0.4	-0.5	1.3	1.7	0.4	0.1	1.4	1.2
Medication: Atenolol	0.4	0.5	1.8	0.1	-0.5	-0.8	-0.6	0.2	-1.4	-1.2	-0.3	-0.7	-0.8	-0.1	-0.3
Mouth/teeth dental problems	0.4	0.6	1.8	0.5	1.2	0.3	1.3	0.8	0.0	0.4	0.4	0.9	1.0	0.6	0.8
Pain all over the body in last month	0.4	0.5	1.5	0.6	-0.4	-0.8	-0.5	-0.4	-0.7	-1.2	-0.8	-0.7	-0.7	-0.6	-0.2
Medication: Simvastatin	0.4	0.6	2.5	1.2	0.8	0.7	0.7	0.9	1.6	-0.6	-0.2	0.4	0.6	0.2	0.4
Medication: Cholesterol lowering	0.4	0.7	4.0	1.6	0.2	0.2	0.2	0.5	0.9	-2.0	-0.4	-0.1	0.0	0.3	0.2
Exposure to tobacco smoke at home	0.4	0.4	2.3	1.5	0.3	-0.2	0.3	0.3	-0.3	-1.0	-0.9	-0.4	0.1	-0.7	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.2	1.0	-0.6	-0.3	-0.7	0.2	-0.3	-0.8	-1.1	-0.5	-0.2	-1.0	-0.8
Eye problems/disorders: None of the above	0.4	0.4	1.2	0.7	0.6	1.1	0.6	1.0	0.2	0.3	0.1	0.6	0.9	0.2	0.3
Medication: Ibuprofen	0.4	0.5	2.6	1.6	0.1	0.6	-0.0	0.3	0.1	-1.0	-0.9	0.1	0.5	-0.5	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.9	-0.1	1.0	0.3	0.9	1.4	-0.2	0.3	0.6	0.3	0.2	0.7	1.0
Average weekly champagne plus white wine intake	0.4	0.6	2.0	0.3	1.0	0.9	0.9	1.4	1.0	-0.4	0.5	0.5	0.3	0.8	0.2
Financial situation satisfaction	0.4	0.5	2.0	1.4	0.7	0.7	0.5	0.1	1.0	-0.6	-0.5	0.7	1.0	0.0	0.1
Medication: Blood pressure	0.4	0.7	2.9	1.4	0.7	0.4	0.5	0.6	1.7	-1.0	-0.8	0.3	0.5	-0.4	-0.0
Ever smoked	0.4	0.7	2.0	-1.3	-1.4	0.4	-1.3	-0.7	0.2	-0.1	0.2	-0.6	-0.9	-0.1	-0.6
Arm fat-free mass (left)	0.4	2.0	7.4	1.0	0.9	0.9	0.8	2.7	0.4	0.2	0.7	2.2	1.9	1.3	1.6
Impedance of whole body	0.4	2.2	6.9	-1.8	-1.4	-0.6	-1.5	-2.6	1.2	0.1	-0.2	-2.0	-2.0	-0.7	-1.0
Leg fat mass (left)	0.4	1.7	5.6	-0.3	-1.4	-2.4	-1.5	-0.6	-1.5	-1.8	-0.8	-1.1	-1.5	-0.8	-0.8
Arm predicted mass (left)	0.4	2.2	7.6	1.0	1.0	0.9	0.9	2.8	0.4	0.2	0.9	2.2	2.0	1.5	1.8
Bipolar Disorder (2018)	0.3	0.5	1.4	-1.2	-0.2	-0.9	-0.1	-0.7	0.2	1.2	1.1	0.5	0.0	0.9	0.2
Alzheimer’s Disease (including proxy)	0.3	0.4	1.5	0.3	-0.6	0.1	-0.9	-1.1	0.5	-0.2	-0.7	0.3	0.2	-0.7	-1.2
Breast Cancer	0.3	0.7	1.6	1.3	0.9	0.9	0.8	-1.0	0.6	0.3	-1.0	-0.2	0.6	-1.2	-0.7
Ulcerative Colitis	0.3	0.4	1.0	0.9	0.7	0.6	0.6	0.7	1.0	0.3	-0.2	0.4	0.8	-0.2	0.5
Blood Red Count	0.3	2.7	9.8	0.8	0.1	-2.9	0.0	0.4	-1.2	-3.1	-1.1	-2.3	-2.3	-0.7	-0.2
Blood White Count	0.3	2.1	7.0	-0.7	-1.3	-2.1	-1.3	-1.5	-2.6	-0.9	-0.9	-0.9	-1.1	-1.1	-1.7
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.7	0.6	-0.4	0.3	-0.3	-0.2	1.3	-0.9	-1.0	-0.5	-0.4	-0.9	-0.9
Chronotype (morning person)	0.3	0.7	4.5	0.4	-0.1	1.1	-0.2	-1.5	2.1	0.1	-0.2	0.6	0.6	-0.1	-0.2
Tanning	0.3	3.6	6.6	-2.3	-2.5	-1.7	-2.4	-2.6	-2.2	-0.3	-0.3	-1.5	-1.9	-0.8	-2.1
Severe depression (siblings)	0.3	0.3	0.9	0.9	-0.1	0.1	-0.2	0.4	0.7	-0.8	-0.9	0.2	0.2	-0.5	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.7	-1.3	-0.2	0.2	-0.2	0.6	-0.2	0.9	1.0	0.5	0.1	0.8	0.5
Qualifications: CSEs or equivalent	0.3	0.4	2.9	-0.4	-0.2	-0.6	-0.0	-0.3	-1.7	-0.0	0.3	-0.9	-0.7	0.1	-0.3
Stomach or abdominal pain in last month	0.3	0.3	1.3	-0.5	-1.2	-0.0	-1.1	0.1	0.4	-0.4	-0.3	-0.1	-0.4	-0.2	-0.5
Had menopause	0.3	0.4	2.1	1.4	0.6	0.3	0.7	0.1	0.4	-0.5	-0.9	0.3	0.5	-0.6	-0.4
Had other major operations	0.3	0.4	1.8	-1.4	-0.8	0.0	-0.8	0.2	0.4	0.9	0.4	0.6	0.1	0.2	-0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.0	1.0	-0.3	-0.3	-0.4	-0.9	0.3	-0.7	-0.7	-0.1	0.2	-0.6	-0.6
Qualifications: None of the above	0.3	0.6	2.9	-1.1	-0.8	-0.2	-0.9	-1.7	-0.2	0.3	-0.0	-0.5	-0.8	-0.4	-0.4
Diabetes (self-reported)	0.3	0.5	1.1	0.2	-0.7	0.1	-0.6	-0.6	0.3	-0.8	-0.9	-0.7	-0.6	-0.9	-1.0
Hip circumference	0.3	1.3	5.0	-1.1	-1.4	-2.2	-1.4	-0.1	-1.4	-1.1	-0.1	-0.8	-1.2	-0.1	0.1
Time employed in main current job	0.3	0.3	0.8	-0.3	0.5	-0.1	0.5	0.6	-0.7	0.6	0.9	0.1	0.1	0.8	0.6
Pulse rate	0.3	0.5	1.2	-0.5	-0.9	-0.6	-0.9	-0.5	-0.6	-0.8	-0.1	-0.8	-1.1	-0.1	-0.6
Asthma	0.3	0.7	2.6	1.6	0.2	0.1	0.2	0.6	0.8	-0.9	-1.4	-0.4	0.1	-1.1	-0.5
Depression (self-reported)	0.3	0.4	1.8	-1.3	-0.8	0.0	-0.9	-0.7	-0.0	0.7	0.5	0.1	-0.3	0.1	-0.3
Worry too long after embarrassment	0.3	0.5	1.5	-0.8	-1.0	-0.4	-1.1	-0.6	-1.2	0.4	0.2	-0.1	-0.3	-0.1	-0.7
Neck or shoulder pain in last month	0.3	0.4	1.4	0.9	0.5	1.2	0.5	-0.3	1.2	0.1	-0.4	0.3	0.6	-0.3	-0.4
Pulse rate, automated reading	0.3	1.0	2.9	-1.7	-1.2	-0.8	-1.3	-0.6	-1.2	-0.2	0.9	-0.7	-1.4	0.7	-0.1
Friendships satisfaction	0.3	0.4	1.3	-0.9	-0.0	0.2	-0.1	0.2	0.5	0.5	0.9	0.6	0.2	0.9	1.1
Eye problems/disorders: Cataract	0.3	0.3	1.0	1.0	0.7	-0.4	0.5	0.7	0.9	-0.8	-0.4	0.1	0.1	0.0	0.2
Medication for cholesterol	0.3	0.4	1.7	1.3	0.2	-0.1	0.4	-0.2	-1.3	-0.6	-0.8	-0.3	0.2	-0.6	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.4	1.2	0.5	0.9	0.4	0.3	0.9	-0.1	-0.3	0.4	0.8	-0.0	0.1
Breast cancer (self-reported)	0.3	0.3	1.2	-0.9	0.3	0.6	0.4	-0.4	0.5	1.1	0.7	0.3	0.2	0.5	0.4
Miserableness	0.3	0.5	2.3	-1.1	-1.4	-0.2	-1.5	-0.5	-0.2	-0.1	-0.0	-0.1	-0.6	-0.0	-0.6
Commuting to job workplace: Public transport	0.3	0.4	1.4	1.2	-0.0	0.0	0.1	-0.1	0.1	-0.5	-1.1	-0.0	0.3	-1.1	-0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.2	0.7	-0.0	0.6	-0.1	1.0	1.1	-0.6	0.4	0.5	0.5	0.7	0.5
Alcohol drinker status: Never	0.3	0.4	0.9	-1.0	-0.2	-0.3	-0.3	0.0	0.3	0.8	0.9	0.7	0.4	0.8	0.6
Basal metabolic rate	0.3	1.7	6.6	0.7	0.8	0.6	0.7	2.6	0.3	0.1	0.8	2.0	1.7	1.3	1.6
Cholesterol lowering medication	0.3	0.5	1.1	-0.9	-1.0	-0.8	-1.0	-0.1	0.3	-0.9	0.1	-0.4	-0.9	0.2	-0.3
Depression (Nagel 2018)	0.2	0.2	1.2	-1.0	-0.1	0.3	-0.1	0.5	-0.3	1.1	0.5	0.3	0.1	0.2	0.2
Schizophrenia vs Biploar Disorder	0.2	0.2	0.6	0.0	-0.4	0.2	-0.5	-0.8	0.3	-0.7	-0.4	-0.2	-0.2	-0.4	-0.7
Worry (Nagel 2018)	0.2	0.3	1.4	0.3	0.0	1.2	-0.2	0.2	0.4	0.5	-0.2	1.0	0.9	-0.2	-0.3
LDL Cholesterol	0.2	0.4	1.7	0.5	0.5	0.6	0.4	0.6	1.3	-0.2	0.4	0.5	0.3	0.7	0.6
Type 2 Diabetes (T2D) (2012)	0.2	0.2	1.3	-0.4	-0.1	0.2	-0.1	0.1	1.1	0.5	0.4	0.6	0.3	0.5	0.3
Smoking Status	0.2	0.4	1.4	-1.1	-1.2	0.5	-1.0	-0.6	0.4	-0.1	0.1	0.0	-0.5	-0.0	-0.8
Neuroticism	0.2	0.5	2.6	-0.5	-1.5	-0.0	-1.6	-0.1	-0.2	-0.6	-0.4	0.3	-0.3	-0.3	-0.6
Hair Pigment	0.2	5.2	14.1	-1.7	2.7	2.5	2.8	0.2	1.3	3.8	2.4	1.7	1.7	1.8	2.8
Sensitivity / hurt feelings	0.2	0.4	1.5	0.3	-1.0	-0.0	-1.2	-0.5	-0.0	-0.6	-0.8	-0.2	-0.1	-0.8	-0.5
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.0	-0.9	-0.4	0.6	-0.4	0.4	0.2	1.0	0.4	0.7	0.6	0.2	0.0
Relative age of first facial hair	0.2	0.3	1.6	-1.0	0.3	0.3	0.3	-0.3	-0.0	1.3	0.8	0.3	0.2	0.4	0.4
Supplements: Zinc	0.2	0.2	1.0	-0.6	-0.3	0.5	-0.4	-0.3	0.1	0.5	0.1	1.0	0.6	0.1	-0.5
Impedance of leg (right)	0.2	1.0	2.9	-1.5	-0.2	0.8	-0.4	-1.7	1.6	1.3	1.0	-0.2	-0.3	0.6	0.2
Leg fat-free mass (left)	0.2	1.0	5.1	0.9	0.5	0.1	0.5	2.3	0.1	-0.4	0.2	1.3	1.2	0.7	1.2
Age when periods started (menarche)	0.2	0.4	1.3	-1.1	-0.1	-0.7	-0.1	-0.8	-0.6	0.5	0.5	-0.7	-0.7	0.2	-0.0
Impedance of leg (left)	0.2	1.1	3.2	-1.8	-0.3	0.7	-0.4	-1.4	1.7	1.1	1.2	-0.5	-0.7	0.8	0.2
Leg predicted mass (left)	0.2	1.0	5.0	0.9	0.5	0.1	0.5	2.2	-0.0	-0.4	0.1	1.3	1.2	0.7	1.2
Past tobacco smoking	0.2	0.3	1.5	0.5	0.6	-0.8	0.6	0.2	-1.2	0.2	-0.1	0.2	0.4	-0.0	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.1	-0.5	-0.9	0.3	-1.0	-0.3	0.5	-0.1	-0.1	0.1	-0.1	-0.1	-0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.2	-0.1	0.2	0.5	0.3	0.5	1.1	0.2	0.2	0.3	0.3	0.3	0.7
Illnesses of siblings	0.2	0.2	1.2	-0.6	0.1	0.3	0.2	-1.1	0.2	0.8	0.3	0.1	0.0	0.1	-0.3
Neuroticism score	0.2	0.5	2.2	-0.9	-1.4	0.2	-1.5	0.0	0.2	-0.2	0.2	0.6	-0.0	0.3	-0.1
Father’s age at death	0.2	0.2	0.5	0.6	0.6	0.6	0.7	0.4	0.6	0.1	-0.1	0.1	0.3	-0.1	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	1.2	1.1	0.4	0.6	0.2	0.5	0.1	-0.5	-0.2	0.3	0.6	0.0	-0.3
Lung cancer (father)	0.2	0.2	0.5	-0.4	-0.7	-0.3	-0.7	-0.1	-0.6	-0.3	-0.0	0.5	0.1	0.1	-0.7
Tense / ‘highly strung’	0.2	0.3	1.5	-0.5	-0.5	0.5	-0.7	0.2	1.2	0.2	0.1	0.5	0.1	0.1	0.2
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.8	0.6	-0.1	-0.5	-0.3	0.1	-0.2	-0.9	-0.7	0.0	-0.1	-0.4	-0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	0.8	0.5	0.7	0.5	0.6	1.0	-0.5	-0.1	-0.0	0.1	0.1	0.6
Glaucoma (self-reported)	0.2	0.3	1.2	0.1	0.5	0.2	0.6	0.5	1.1	0.3	0.4	0.1	0.2	0.5	0.8
Birth weight	0.2	0.5	1.9	0.9	0.0	0.9	-0.2	0.8	0.4	-0.3	-0.5	1.4	1.2	0.0	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.8	0.1	-0.1	0.9	-0.3	0.9	0.3	0.5	0.1	0.7	0.8	0.1	-0.1
Age at last live birth	0.2	0.3	1.0	1.0	0.9	-0.1	1.0	-0.4	-0.0	-0.2	-0.5	-0.6	-0.1	-0.5	-0.3
Leg fat-free mass (right)	0.2	1.2	6.7	0.8	0.6	0.2	0.6	2.6	0.1	-0.3	0.4	1.4	1.2	0.9	1.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.8	-1.4	-0.5	0.4	-0.5	-0.6	-0.0	1.0	0.5	-0.2	-0.4	0.1	0.3
Asthma (self-reported)	0.2	0.5	1.5	1.1	-0.1	-0.0	-0.0	0.5	0.6	-0.8	-1.2	-0.5	-0.1	-1.1	-0.5
Osteoarthritis (self-reported)	0.2	0.2	0.7	0.6	-0.0	0.3	-0.1	0.0	0.1	-0.8	-0.6	-0.2	-0.2	-0.4	-0.8
Leg predicted mass (right)	0.2	1.3	7.0	0.9	0.7	0.3	0.7	2.6	0.2	-0.4	0.4	1.4	1.3	0.9	1.3
High cholesterol (Self-reported)	0.2	0.4	1.8	-0.6	0.2	0.0	0.1	0.6	0.2	-0.1	1.1	0.3	-0.1	1.4	0.9
Medication: Bendroflumethiazide	0.2	0.3	0.8	-0.2	-0.4	0.1	-0.5	-0.9	0.9	0.0	-0.7	0.0	-0.0	-0.8	-0.7
Number of operations (self-reported)	0.2	0.3	1.6	0.2	-0.8	0.5	-0.8	-0.5	1.3	0.1	-0.3	0.3	0.3	-0.3	-0.6
Basal cell carcinoma (self-reported)	0.2	0.2	1.0	1.0	0.4	-0.4	0.2	0.2	0.1	-0.8	-0.4	-0.1	0.1	-0.0	-0.1
Neuroticism (Nagel 2018)	0.1	0.3	1.5	-0.4	-1.1	-0.2	-1.2	-0.0	-0.1	-0.6	-0.4	-0.0	-0.2	-0.2	-0.3
Neuroticism (2016)	0.1	0.2	0.5	-0.7	-0.7	-0.1	-0.6	-0.0	-0.2	-0.3	-0.3	-0.4	-0.4	-0.3	-0.3
Respiratory disease	0.1	0.3	1.0	0.4	-0.2	-0.2	-0.2	-0.1	1.0	-0.1	-0.9	-0.5	-0.2	-0.9	-0.3
Lung FVC	0.1	0.6	2.0	-0.1	1.1	0.2	1.1	1.4	-1.2	0.7	0.6	0.1	0.3	0.5	0.5
Average weekly spirits intake	0.1	0.1	0.8	0.3	0.2	0.6	0.2	-0.1	0.9	0.0	-0.4	0.1	0.3	-0.4	-0.1
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.5	-0.1	0.5	-0.2	0.7	-0.2	-0.7	-0.0	0.5	-0.1	-0.1	0.5	0.1
Medication: Metformin	0.1	0.1	0.5	-0.1	-0.1	0.7	-0.1	-0.3	0.6	0.2	-0.3	-0.0	0.1	-0.4	-0.3
Diabetes (father)	0.1	0.1	0.7	0.6	0.2	0.3	0.1	-0.0	0.8	-0.4	-0.3	-0.4	-0.1	-0.3	-0.1
Hearing difficulty/problems with background noise	0.1	0.2	0.9	0.4	0.1	0.6	0.1	0.1	0.9	-0.0	-0.3	0.4	0.4	-0.2	-0.2
Allergy	0.1	0.2	1.3	0.9	-0.2	-0.1	-0.2	-0.2	-0.1	-1.1	-0.6	-0.1	0.1	-0.2	-0.6
Weight	0.1	0.4	1.4	-0.4	-0.9	-1.2	-0.9	0.6	-0.6	-0.7	-0.1	0.3	-0.1	0.1	0.3
Worrier / anxious feelings	0.1	0.2	0.6	0.7	-0.2	0.3	-0.4	0.1	-0.1	-0.7	-0.6	0.3	0.3	-0.3	-0.7
Noisy workplace	0.1	0.2	1.1	-0.3	-0.4	-0.3	-0.3	-0.3	-1.0	-0.2	-0.0	-0.2	-0.4	-0.1	-0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.4	-0.8	0.1	0.1	0.1	0.5	-0.0	1.2	0.6	0.3	0.3	0.3	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.5	-0.5	-0.0	-0.5	-0.2	0.0	-0.5	-0.4	-0.1	0.0	-0.4	-0.4
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.4	0.1	0.2	0.6	0.4	0.6	0.3	0.6	0.2	0.3	0.5	0.1	0.3
Headache pain in last month	0.1	0.2	0.4	-0.5	-0.7	-0.2	-0.6	0.6	-0.2	-0.2	-0.0	-0.2	-0.5	-0.0	-0.2
Medication: Amlodipine	0.1	0.1	0.3	0.3	-0.4	-0.1	-0.4	-0.5	0.3	-0.3	-0.4	-0.2	-0.1	-0.4	-0.6
Medication: Seretide 50 evohaler	0.1	0.2	1.0	-0.6	-0.1	-0.1	-0.0	-0.0	0.4	1.0	0.5	-0.1	-0.0	0.1	0.5
Suffer from ‘nerves’	0.1	0.2	1.3	0.3	-0.5	0.0	-0.6	0.5	-1.1	-0.2	-0.1	0.3	0.4	-0.0	-0.3
Illnesses of father: Heart disease	0.1	0.2	0.8	0.8	0.4	-0.1	0.3	-0.1	-0.7	-0.9	-0.2	-0.2	-0.2	-0.1	-0.4
Smoking status: Previous	0.1	0.2	0.9	-0.4	-0.2	0.5	-0.1	0.8	0.9	-0.5	0.3	-0.2	-0.5	0.4	0.1
Guilty feelings	0.1	0.2	0.5	-0.3	-0.7	-0.5	-0.7	-0.6	-0.4	-0.4	-0.1	-0.4	-0.6	-0.1	-0.4
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.5	0.6	-0.3	-0.1	-0.2	-0.7	0.3	-0.3	-0.5	-0.3	-0.0	-0.5	-0.4
Eye problems/disorders: Glaucoma	0.1	0.1	0.4	-0.6	-0.0	-0.4	0.0	-0.1	0.5	0.5	0.5	-0.2	-0.2	0.3	0.5
Age started oral contraceptive pill	0.1	0.2	1.0	-0.2	0.4	0.0	0.4	-0.7	0.1	1.0	0.1	0.2	0.2	-0.2	-0.2
Diastolic blood pressure, automated reading	0.1	0.4	2.5	0.3	-0.0	-1.6	-0.1	0.7	-0.5	-1.1	0.3	0.0	-0.3	0.7	0.4
Unable to work because of sickness or disability	0.1	0.2	0.5	-0.6	-0.6	-0.1	-0.7	-0.3	-0.1	-0.0	0.6	-0.0	-0.1	0.6	-0.1
Commuting to job workplace: Cycle	0.1	0.1	0.3	0.0	0.1	0.4	0.3	0.4	0.1	0.6	0.0	0.3	0.6	-0.1	0.3
Pain experienced in last month	0.1	0.1	0.6	0.2	0.6	-0.2	0.8	-0.2	-0.2	0.5	-0.1	0.2	0.5	-0.3	0.0
Heart disease (siblings)	0.1	0.1	0.2	0.3	0.5	0.0	0.5	0.3	-0.1	0.2	0.2	0.1	0.2	0.2	0.4
Medication: Ventolin 100micrograms inhaler	0.0	0.1	0.3	0.2	-0.2	0.2	0.0	-0.0	0.2	-0.1	-0.2	-0.5	-0.3	-0.3	-0.1

Hub : Genes

ZNF573

Models

Trait associations