[Hub]/) : Traits : Leg pain on walking :

chr3:49,030,828-50,800,146

Best TWAS P=9.35e-09 · Best GWAS P=2.1e-07 conditioned to 0.67

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Tibial	IP6K1	0.03	0.00	enet	22	0.01	2.5e-02	4.6	5.7	9.3e-09	-0.62	0.09	0.64	TRUE
1	CommonMind	Brain Pre-frontal Cortex	RNF123	0.14	0.10	blup	324	0.12	4.7e-14	4.8	5.6	2.0e-08	-0.73	0.14	0.86	TRUE
14	METSIM	Adipose	MST1R	0.03	0.02	blup	331	0.02	1.7e-03	5.1	5.7	1.3e-08	-0.85	0.06	0.93	FALSE
6	GTEx	Brain Cerebellum	MST1R	0.19	0.24	enet	22	0.20	1.8e-06	-5.1	5.5	3.7e-08	-0.95	0.06	0.94	FALSE
7	GTEx	Breast Mammary Tissue	RNF123	0.11	0.07	enet	14	0.02	3.2e-02	4.7	5.4	7.2e-08	-0.67	0.15	0.78	FALSE
3	GTEx	Artery Tibial	MST1R	0.06	0.02	lasso	5	0.02	1.5e-02	4.6	5.4	8.1e-08	-0.81	0.08	0.60	FALSE
2	GTEx	Artery Coronary	RBM6	0.14	0.14	enet	23	0.15	1.0e-05	4.8	-5.3	8.9e-08	0.86	0.11	0.88	FALSE
11	GTEx	Spleen	RBM6	0.36	0.39	lasso	8	0.40	2.0e-11	-5.2	-5.3	1.0e-07	0.99	0.04	0.95	FALSE
9	GTEx	Esophagus Mucosa	RBM6	0.18	0.21	enet	18	0.23	3.0e-15	5.1	-5.3	1.1e-07	0.94	0.06	0.94	FALSE
12	GTEx	Vagina	RBM6	0.24	0.22	enet	27	0.21	1.5e-05	-4.1	-5.3	1.1e-07	0.95	0.07	0.92	FALSE
13	GTEx	Whole Blood	UBA7	0.03	0.04	lasso	2	0.01	1.5e-02	4.8	-5.3	1.4e-07	0.79	0.11	0.78	FALSE
10	GTEx	Lung	RBM6	0.17	0.20	lasso	6	0.24	4.6e-18	-5.1	-5.2	2.1e-07	0.97	0.08	0.92	FALSE
5	GTEx	Artery Tibial	UBA7	0.04	0.03	lasso	4	0.02	7.8e-03	-5.0	-5.2	2.2e-07	0.86	0.07	0.64	FALSE
8	GTEx	Colon Transverse	RBM6	0.29	0.33	enet	43	0.36	4.6e-18	-4.6	-5.1	2.8e-07	0.95	0.13	0.87	FALSE