Best TWAS P=2.63e-12 · Best GWAS P=7.97e-12 conditioned to 0.797
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | AFF3 | 0.14 | 0.06 | lasso | 5 | 0.07 | 1.2e-04 | -6.8 | -7.0 | 2.6e-12 | 0.84 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | LONRF2 | 0.05 | 0.03 | lasso | 2 | 0.02 | 9.3e-03 | 5.2 | -6.0 | 2.6e-09 | 0.56 | 0.13 | 0.64 | TRUE |
| 3 | GTEx | Thyroid | CHST10 | 0.05 | 0.05 | lasso | 5 | 0.03 | 2.6e-03 | -4.9 | -6.0 | 2.7e-09 | 0.60 | 0.41 | 0.37 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LONRF2 | 0.06 | 0.04 | blup | 69 | 0.04 | 3.4e-05 | 4.9 | -6.2 | 6.4e-10 | 0.68 | 0.54 | 0.44 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LONRF2 | 0.05 | 0.08 | lasso | 2 | 0.08 | 2.9e-05 | 5.4 | -5.3 | 1.4e-07 | 0.66 | 0.22 | 0.14 | FALSE |