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Traits
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Traits
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Hip circumference
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chr4:144,882,744-146,788,825
Best TWAS P=1.21e-28 · Best GWAS P=8.2e-31 conditioned to 0.596
145M
145.5M
146M
146.5M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
ROSMAP
Brain Pre-frontal Cortex
OTUD4
0.04
0.03
lasso
2
0.03
1.4e-04
11.0
-11.1
1.2e-28
-0.85
0.10
0.85
TRUE
2
GTEx
Brain Hypothalamus
HHIP-AS1
0.12
0.02
enet
16
0.04
4.6e-02
7.1
5.9
4.2e-09
0.21
0.07
0.08
TRUE
1
CommonMind
Brain Pre-frontal Cortex
OTUD4
0.06
0.04
bslmm
272
0.04
2.6e-05
-7.8
-5.7
1.1e-08
-0.39
0.84
0.04
TRUE
3
GTEx
Pancreas
ANAPC10
0.14
0.10
lasso
3
0.10
4.3e-05
-9.5
8.9
7.9e-19
0.60
0.32
0.11
FALSE