[Hub]/) : Traits : Hip circumference : ← →

chr6:41,005,502-42,934,620

Best TWAS P=2.53e-16 · Best GWAS P=3.15e-18 conditioned to 2.28e-05

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
28	The Cancer Genome Atlas	Colon Adenocarcinoma	MED20	0.05	0.00	blup	50	0.04	2.8e-03	6.23	8.2	2.5e-16	0.70	0.06	0.32	TRUE
32	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UBR2	0.10	0.01	blup	77	0.04	9.1e-03	4.97	-6.0	2.6e-09	0.01	0.01	0.61	TRUE
7	GTEx	Colon Transverse	MED20	0.17	0.01	enet	10	0.06	6.0e-04	6.32	7.7	9.6e-15	0.69	0.18	0.59	FALSE
13	GTEx	Lung	BYSL	0.08	0.03	lasso	4	0.02	4.9e-03	8.33	-7.5	5.5e-14	-0.80	0.08	0.88	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	MED20	0.09	0.08	enet	12	0.09	5.5e-10	6.37	7.2	5.0e-13	0.62	1.00	0.00	FALSE
20	GTEx	Thyroid	FRS3	0.20	0.16	lasso	4	0.16	5.2e-12	8.02	7.2	5.8e-13	0.67	0.26	0.74	FALSE
33	The Cancer Genome Atlas	Prostate Adenocarcinoma	MED20	0.04	0.06	enet	6	0.05	2.6e-06	6.23	7.0	3.0e-12	0.58	0.90	0.02	FALSE
5	GTEx	Cells Transformed fibroblasts	MED20	0.11	0.05	lasso	4	0.08	9.4e-07	-6.73	6.9	4.4e-12	0.46	0.87	0.09	FALSE
31	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MED20	0.09	0.07	lasso	5	0.07	3.4e-04	-5.83	6.9	6.8e-12	0.51	0.18	0.54	FALSE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MED20	0.04	0.03	lasso	3	0.04	7.3e-05	-6.73	6.7	2.0e-11	0.45	0.57	0.02	FALSE
34	The Cancer Genome Atlas	Stomach Adenocarcinoma	MED20	0.03	0.05	lasso	2	0.04	1.2e-03	-6.73	6.7	2.4e-11	0.44	0.11	0.06	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	PGC	0.13	0.06	blup	520	0.06	3.2e-08	8.02	-6.4	1.5e-10	-0.58	0.17	0.83	FALSE
19	GTEx	Thyroid	MED20	0.05	0.05	lasso	2	0.02	8.1e-03	6.44	6.4	1.8e-10	0.61	0.44	0.43	FALSE
4	GTEx	Artery Tibial	MED20	0.14	0.11	lasso	2	0.09	9.7e-08	6.37	6.4	2.0e-10	0.60	0.99	0.01	FALSE
9	GTEx	Esophagus Muscularis	MED20	0.15	0.05	lasso	7	0.04	1.0e-03	-5.32	6.4	2.1e-10	0.62	0.38	0.56	FALSE
12	GTEx	Heart Left Ventricle	MED20	0.22	0.19	enet	8	0.12	5.8e-07	6.32	6.3	2.7e-10	0.61	1.00	0.00	FALSE
21	METSIM	Adipose	MED20	0.13	0.11	enet	27	0.11	2.3e-16	6.28	6.3	2.7e-10	0.61	1.00	0.00	FALSE
15	GTEx	Muscle Skeletal	MED20	0.16	0.15	lasso	4	0.16	6.7e-16	6.23	6.3	3.2e-10	0.60	1.00	0.00	FALSE
11	GTEx	Heart Left Ventricle	PRICKLE4	0.11	0.05	lasso	4	0.03	9.8e-03	6.23	-6.2	4.9e-10	-0.59	0.26	0.07	FALSE
17	GTEx	Spleen	MED20	0.44	0.13	enet	23	0.07	6.4e-03	6.37	6.2	5.3e-10	0.57	0.11	0.49	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCND3	0.04	0.00	blup	99	0.01	1.8e-03	-5.74	6.2	7.4e-10	0.45	0.02	0.12	FALSE
2	GTEx	Adipose Subcutaneous	MED20	0.08	0.07	enet	9	0.05	4.7e-05	6.27	6.1	9.5e-10	0.61	0.96	0.01	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	MED20	0.10	0.10	enet	21	0.09	6.0e-12	6.44	6.1	1.3e-09	0.61	1.00	0.00	FALSE
18	GTEx	Testis	MED20	0.13	0.03	lasso	6	0.00	2.0e-01	-5.83	6.0	1.5e-09	0.46	0.15	0.18	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	BYSL	0.05	0.06	enet	7	0.06	4.3e-06	6.44	-6.0	2.5e-09	-0.56	0.83	0.09	FALSE
16	GTEx	Nerve Tibial	MED20	0.13	0.11	enet	8	0.10	1.5e-07	6.19	5.9	3.7e-09	0.58	1.00	0.00	FALSE
10	GTEx	Heart Atrial Appendage	MED20	0.14	0.12	enet	11	0.09	5.9e-05	6.19	5.9	3.8e-09	0.58	0.83	0.10	FALSE
25	YFS	Blood	MED20	0.04	0.03	lasso	5	0.03	3.6e-11	6.23	5.8	7.1e-09	0.61	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MED20	0.15	0.11	blup	471	0.13	3.1e-15	-5.39	5.7	1.2e-08	0.61	1.00	0.00	FALSE
8	GTEx	Esophagus Mucosa	MED20	0.09	0.07	enet	10	0.02	2.7e-02	-5.39	5.7	1.3e-08	0.59	0.76	0.14	FALSE
14	GTEx	Lung	USP49	0.09	0.08	lasso	2	0.05	6.2e-05	-5.81	-5.4	7.0e-08	-0.33	0.84	0.01	FALSE
3	GTEx	Adipose Subcutaneous	FRS3	0.15	0.04	enet	22	0.04	5.9e-04	8.02	5.4	7.4e-08	0.57	0.13	0.72	FALSE
6	GTEx	Cells Transformed fibroblasts	USP49	0.13	0.02	lasso	4	0.02	2.4e-02	-5.81	-5.3	9.6e-08	-0.37	0.29	0.03	FALSE
26	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PRPH2	0.07	0.03	enet	6	0.06	1.9e-05	5.97	-5.3	1.1e-07	0.03	0.00	0.99	FALSE
24	YFS	Blood	GUCA1B	0.03	0.01	bslmm	402	0.01	1.4e-03	0.81	-5.2	2.7e-07	-0.15	0.30	0.02	FALSE