[Hub]/) : Traits : Hip circumference :

chr6:33,662,667-36,581,149

Best TWAS P=2.16e-55 · Best GWAS P=4.46e-57 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C6orf106 0.29 0.21 bslmm 382 0.23 6.9e-28 15.63 12.8 3.0e-37 0.84 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex PACSIN1 0.07 0.01 lasso 6 0.02 1.1e-03 15.92 13.8 4.5e-43 0.82 0.01 0.97 FALSE
3 CommonMind Brain Pre-frontal Cortex RPL10A 0.21 0.09 enet 30 0.11 2.6e-13 -4.19 -5.8 6.3e-09 -0.12 1.00 0.00 FALSE
4 CommonMind Brain Pre-frontal Cortex SNRPC 0.10 0.16 lasso 4 0.15 3.6e-18 12.42 -13.3 2.8e-40 -0.65 1.00 0.00 FALSE
5 CommonMind Brain Pre-frontal Cortex UHRF1BP1 0.17 0.23 lasso 19 0.22 5.8e-27 12.42 12.4 1.6e-35 0.58 1.00 0.00 FALSE
6 GTEx Adipose Subcutaneous UHRF1BP1 0.30 0.35 enet 28 0.36 1.6e-30 12.50 12.8 1.2e-37 0.60 1.00 0.00 FALSE
7 GTEx Adipose Subcutaneous SNRPC 0.13 0.13 enet 21 0.13 1.2e-10 12.50 -10.6 4.3e-26 -0.39 1.00 0.00 TRUE
8 GTEx Adipose Visceral Omentum UHRF1BP1 0.30 0.34 lasso 3 0.34 3.0e-18 12.32 12.4 1.5e-35 0.58 1.00 0.00 FALSE
9 GTEx Adrenal Gland UHRF1BP1 0.32 0.26 enet 33 0.33 1.3e-12 12.50 7.5 9.1e-14 0.29 1.00 0.00 FALSE
10 GTEx Adrenal Gland SNRPC 0.13 0.04 lasso 6 0.03 2.7e-02 13.84 -11.6 6.3e-31 -0.57 0.18 0.35 FALSE
11 GTEx Artery Aorta UHRF1BP1 0.35 0.32 lasso 10 0.30 7.7e-17 12.37 12.7 1.1e-36 0.58 1.00 0.00 FALSE
12 GTEx Artery Coronary UHRF1BP1 0.33 0.36 lasso 2 0.35 1.6e-12 12.50 12.5 7.7e-36 0.59 1.00 0.00 FALSE
13 GTEx Artery Tibial UHRF1BP1 0.31 0.43 lasso 11 0.43 4.0e-36 12.50 11.6 6.6e-31 0.52 1.00 0.00 FALSE
14 GTEx Artery Tibial SNRPC 0.06 0.06 lasso 4 0.05 1.3e-04 12.54 -12.8 1.1e-37 -0.61 0.96 0.01 FALSE
15 GTEx Artery Tibial RPL10A 0.11 0.08 lasso 2 0.09 1.5e-07 -4.11 -5.7 1.3e-08 -0.13 1.00 0.00 FALSE
16 GTEx Brain Caudate basal ganglia UHRF1BP1 0.19 0.14 lasso 7 0.12 3.1e-04 12.44 10.9 1.3e-27 0.46 0.40 0.05 TRUE
17 GTEx Brain Caudate basal ganglia SNRPC 0.19 0.15 lasso 3 0.06 7.7e-03 12.49 -13.7 1.3e-42 -0.65 0.36 0.21 FALSE
18 GTEx Brain Cerebellar Hemisphere UHRF1BP1 0.22 0.16 lasso 12 0.15 1.0e-04 12.49 12.9 6.4e-38 0.63 0.11 0.75 FALSE
19 GTEx Brain Cerebellum UHRF1BP1 0.14 0.09 enet 23 0.12 1.5e-04 12.44 10.8 2.6e-27 0.51 0.17 0.28 FALSE
20 GTEx Brain Cortex C6orf106 0.22 0.07 enet 16 0.10 1.1e-03 15.91 11.8 6.9e-32 0.75 0.01 0.98 TRUE
21 GTEx Brain Frontal Cortex BA9 UHRF1BP1 0.18 0.00 lasso 10 0.02 7.3e-02 12.59 6.8 1.3e-11 0.38 0.12 0.10 FALSE
22 GTEx Brain Frontal Cortex BA9 RPS10 0.21 0.08 lasso 3 0.06 8.6e-03 5.53 8.1 5.7e-16 0.26 0.11 0.13 TRUE
23 GTEx Brain Putamen basal ganglia UHRF1BP1 0.20 0.17 lasso 2 0.16 1.5e-04 12.37 12.5 9.8e-36 0.59 0.22 0.19 FALSE
24 GTEx Breast Mammary Tissue UHRF1BP1 0.34 0.28 enet 46 0.29 4.7e-15 12.32 11.6 4.1e-31 0.51 1.00 0.00 FALSE
25 GTEx Breast Mammary Tissue (Male) UHRF1BP1 0.19 0.16 enet 24 0.08 5.6e-03 12.37 12.4 3.4e-35 0.59 0.42 0.09 FALSE
26 GTEx Breast Mammary Tissue (Female) UHRF1BP1 0.23 0.21 lasso 3 0.20 1.0e-06 12.50 11.3 2.0e-29 0.49 0.80 0.07 FALSE
27 GTEx Cells EBV-transformed lymphocytes UHRF1BP1 0.37 0.08 enet 46 0.11 1.7e-04 12.48 7.9 4.0e-15 0.52 0.20 0.59 FALSE
28 GTEx Cells EBV-transformed lymphocytes C6orf106 0.20 0.00 lasso 5 0.00 2.7e-01 14.72 12.7 7.5e-37 0.80 0.03 0.58 FALSE
29 GTEx Cells Transformed fibroblasts DEF6 0.14 0.03 enet 35 0.04 9.7e-04 5.00 -5.7 1.2e-08 -0.17 0.60 0.01 FALSE
30 GTEx Cells Transformed fibroblasts UHRF1BP1 0.34 0.32 enet 44 0.31 2.4e-23 12.50 13.7 1.4e-42 0.64 1.00 0.00 FALSE
31 GTEx Cells Transformed fibroblasts RPS10 0.12 0.05 lasso 4 0.06 4.5e-05 8.71 7.8 4.7e-15 0.12 0.98 0.00 TRUE
32 GTEx Cells Transformed fibroblasts NUDT3 0.11 0.03 lasso 3 0.02 9.2e-03 7.37 -6.3 3.9e-10 -0.14 0.24 0.03 FALSE
33 GTEx Colon Sigmoid UHRF1BP1 0.44 0.36 lasso 12 0.38 1.8e-14 12.50 10.9 8.4e-28 0.44 1.00 0.00 FALSE
34 GTEx Colon Transverse UHRF1BP1 0.42 0.28 lasso 4 0.28 1.6e-13 12.32 13.4 1.1e-40 0.64 1.00 0.00 FALSE
35 GTEx Colon Transverse C6orf106 0.15 0.05 lasso 1 0.03 1.5e-02 12.28 12.3 1.2e-34 0.61 0.05 0.70 FALSE
36 GTEx Esophagus Gastroesophageal Junction UHRF1BP1 0.47 0.38 enet 22 0.43 7.3e-17 12.51 10.6 3.2e-26 0.50 1.00 0.00 FALSE
37 GTEx Esophagus Mucosa UHRF1BP1 0.14 0.15 enet 28 0.17 1.3e-11 12.30 13.2 1.6e-39 0.65 1.00 0.00 FALSE
38 GTEx Esophagus Mucosa SNRPC 0.12 0.10 lasso 2 0.08 4.8e-06 12.41 -12.5 1.3e-35 -0.58 0.99 0.00 FALSE
39 GTEx Esophagus Mucosa RPL10A 0.14 0.10 enet 17 0.09 2.1e-06 -4.11 -6.6 3.2e-11 -0.15 0.94 0.01 FALSE
40 GTEx Esophagus Muscularis UHRF1BP1 0.42 0.35 enet 48 0.33 1.0e-20 12.49 12.0 3.5e-33 0.46 1.00 0.00 TRUE
41 GTEx Esophagus Muscularis SNRPC 0.09 0.11 lasso 3 0.07 3.8e-05 12.50 -12.4 3.5e-35 -0.59 0.98 0.00 FALSE
42 GTEx Esophagus Muscularis NUDT3 0.12 0.00 lasso 7 0.02 3.2e-02 8.98 -7.4 1.1e-13 -0.17 0.13 0.10 FALSE
43 GTEx Heart Atrial Appendage UHRF1BP1 0.13 0.07 enet 17 0.05 1.9e-03 12.54 10.4 3.2e-25 0.38 0.54 0.08 FALSE
44 GTEx Heart Left Ventricle UHRF1BP1 0.23 0.12 lasso 7 0.22 1.2e-11 12.32 8.1 3.9e-16 0.33 1.00 0.00 FALSE
45 GTEx Liver UHRF1BP1 0.13 0.04 lasso 3 0.05 1.8e-02 12.50 12.6 1.2e-36 0.50 0.14 0.23 FALSE
46 GTEx Lung UHRF1BP1 0.17 0.20 enet 22 0.18 4.3e-14 12.48 12.9 4.6e-38 0.57 1.00 0.00 FALSE
47 GTEx Muscle Skeletal UHRF1BP1 0.34 0.34 enet 45 0.39 4.3e-40 12.50 9.1 1.1e-19 0.34 1.00 0.00 FALSE
48 GTEx Muscle Skeletal SNRPC 0.03 0.02 lasso 3 0.02 8.3e-03 12.54 -13.9 8.6e-44 -0.69 0.14 0.63 FALSE
49 GTEx Muscle Skeletal C6orf106 0.08 0.06 lasso 4 0.06 7.1e-07 13.81 -14.8 2.2e-49 -0.88 0.02 0.98 FALSE
50 GTEx Muscle Skeletal RPL10A 0.10 0.05 enet 17 0.04 3.9e-05 -4.19 -5.2 1.6e-07 -0.14 0.72 0.02 FALSE
51 GTEx Nerve Tibial UHRF1BP1 0.31 0.31 lasso 6 0.31 3.9e-22 12.50 12.7 4.8e-37 0.58 1.00 0.00 FALSE
52 GTEx Nerve Tibial SNRPC 0.12 0.10 lasso 4 0.08 1.5e-06 12.50 -12.5 4.2e-36 -0.59 1.00 0.00 FALSE
53 GTEx Nerve Tibial C6orf106 0.11 0.07 enet 17 0.07 1.3e-05 15.63 13.6 5.2e-42 0.89 0.01 0.99 FALSE
54 GTEx Pancreas C6orf106 0.14 0.11 enet 11 0.13 2.8e-06 13.84 15.0 1.2e-50 0.89 0.02 0.98 FALSE
55 GTEx Skin Not Sun Exposed Suprapubic UHRF1BP1 0.20 0.10 enet 30 0.15 2.1e-08 12.37 7.1 1.6e-12 0.21 0.99 0.00 FALSE
56 GTEx Skin Sun Exposed Lower leg UHRF1BP1 0.19 0.13 enet 33 0.14 2.7e-11 12.50 12.2 5.2e-34 0.53 1.00 0.00 FALSE
57 GTEx Skin Sun Exposed Lower leg SRPK1 0.14 0.00 enet 27 0.02 1.2e-02 -3.93 6.0 2.3e-09 0.18 0.24 0.06 TRUE
58 GTEx Skin Sun Exposed Lower leg SNRPC 0.03 0.04 lasso 2 0.03 1.9e-03 12.50 -12.5 6.0e-36 -0.59 0.55 0.07 FALSE
59 GTEx Skin Sun Exposed Lower leg C6orf106 0.09 0.04 enet 25 0.02 4.6e-03 0.49 6.9 4.0e-12 0.56 0.11 0.71 FALSE
60 GTEx Small Intestine Terminal Ileum UHRF1BP1 0.20 0.03 lasso 5 0.00 3.4e-01 12.48 12.8 1.7e-37 0.60 0.14 0.10 FALSE
61 GTEx Spleen UHRF1BP1 0.34 0.21 enet 36 0.17 4.5e-05 12.41 12.9 5.8e-38 0.54 0.62 0.04 FALSE
62 GTEx Stomach UHRF1BP1 0.24 0.22 enet 20 0.23 2.2e-11 11.74 13.0 1.8e-38 0.57 1.00 0.00 FALSE
63 GTEx Testis RPS10 0.17 0.11 lasso 1 0.04 5.2e-03 5.88 5.9 4.0e-09 0.07 0.30 0.04 FALSE
64 GTEx Thyroid UHRF1BP1 0.13 0.06 enet 37 0.08 5.9e-07 3.94 7.8 5.2e-15 0.23 0.99 0.00 FALSE
65 GTEx Thyroid SNRPC 0.07 0.04 lasso 6 0.05 1.6e-04 12.49 -12.4 3.5e-35 -0.57 0.81 0.03 FALSE
66 GTEx Thyroid C6orf106 0.09 0.01 enet 29 0.01 1.1e-01 15.86 10.3 5.5e-25 0.75 0.01 0.87 FALSE
67 GTEx Thyroid RPL10A 0.16 0.09 lasso 11 0.07 8.9e-06 -6.69 -6.7 2.1e-11 -0.16 0.89 0.00 TRUE
68 GTEx Uterus UHRF1BP1 0.20 0.03 lasso 4 0.07 1.8e-02 12.50 15.1 3.0e-51 0.72 0.08 0.33 FALSE
69 GTEx Vagina UHRF1BP1 0.31 0.05 lasso 8 0.04 5.0e-02 12.50 12.7 9.0e-37 0.59 0.09 0.51 FALSE
70 GTEx Whole Blood UHRF1BP1 0.14 0.14 lasso 7 0.14 2.9e-13 12.49 12.2 2.1e-34 0.55 1.00 0.00 FALSE
71 METSIM Adipose C6orf106 0.04 0.02 blup 381 0.02 7.7e-04 9.20 9.9 2.9e-23 0.60 0.03 0.92 FALSE
72 METSIM Adipose SNRPC 0.05 0.05 lasso 7 0.07 2.9e-11 12.37 -8.4 4.9e-17 -0.32 1.00 0.00 FALSE
73 METSIM Adipose UHRF1BP1 0.16 0.31 enet 30 0.32 1.0e-49 12.54 10.8 2.4e-27 0.49 1.00 0.00 FALSE
74 NTR Blood C6orf106 0.03 0.02 lasso 6 0.02 7.2e-07 15.82 15.7 2.2e-55 0.98 0.01 0.99 TRUE
75 NTR Blood UHRF1BP1 0.03 0.05 enet 19 0.05 7.4e-15 12.29 12.0 4.6e-33 0.63 1.00 0.00 FALSE
76 ROSMAP Brain Pre-frontal Cortex TEAD3 0.07 0.03 bslmm 421 0.04 5.6e-06 3.42 -5.5 3.4e-08 -0.26 0.78 0.03 FALSE
77 ROSMAP Brain Pre-frontal Cortex UHRF1BP1 0.16 0.27 lasso 10 0.28 2.7e-36 12.29 12.0 4.0e-33 0.54 1.00 0.00 FALSE
78 ROSMAP Brain Pre-frontal Cortex PACSIN1 0.09 0.00 blup 359 0.02 4.5e-04 15.63 11.3 2.1e-29 0.69 0.01 0.94 FALSE
79 ROSMAP Brain Pre-frontal Cortex SNRPC 0.15 0.27 lasso 4 0.27 4.0e-35 12.54 -12.6 3.4e-36 -0.58 1.00 0.00 FALSE
80 ROSMAP Brain Pre-frontal Cortex C6orf106 0.30 0.26 bslmm 372 0.33 9.3e-44 15.82 12.9 3.1e-38 0.86 0.01 0.99 FALSE
81 YFS Blood RPS10 0.05 0.05 bslmm 353 0.05 2.2e-16 6.33 5.5 3.4e-08 0.11 1.00 0.00 FALSE
82 YFS Blood SNRPC 0.02 0.03 lasso 5 0.02 3.0e-08 12.51 -12.4 2.9e-35 -0.62 0.98 0.02 FALSE
83 YFS Blood UHRF1BP1 0.18 0.34 enet 36 0.34 2.5e-117 12.48 13.0 1.2e-38 0.63 1.00 0.00 FALSE
84 The Cancer Genome Atlas Bladder Urothelial Carcinoma UHRF1BP1 0.03 0.04 lasso 3 0.04 1.7e-04 12.50 12.5 7.2e-36 0.59 0.32 0.04 FALSE
85 The Cancer Genome Atlas Breast Invasive Carcinoma RPS10 0.01 0.01 enet 1 0.01 1.2e-02 6.33 6.3 2.5e-10 0.11 0.17 0.07 FALSE
86 The Cancer Genome Atlas Breast Invasive Carcinoma SNRPC 0.01 0.01 blup 31 0.00 3.0e-02 4.02 -12.3 1.5e-34 -0.56 0.03 0.04 FALSE
87 The Cancer Genome Atlas Breast Invasive Carcinoma UHRF1BP1 0.04 0.05 lasso 3 0.04 8.4e-09 12.44 12.5 1.4e-35 0.58 1.00 0.00 FALSE
88 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma UHRF1BP1 0.07 0.11 lasso 3 0.07 2.6e-04 12.32 12.3 7.4e-35 0.58 0.73 0.05 FALSE
89 The Cancer Genome Atlas Colon Adenocarcinoma UHRF1BP1 0.08 0.11 lasso 12 0.10 2.3e-06 12.54 12.4 3.2e-35 0.58 0.98 0.00 FALSE
90 The Cancer Genome Atlas Esophageal Carcinoma UHRF1BP1 0.19 0.20 lasso 10 0.17 5.2e-06 12.32 12.4 3.3e-35 0.58 0.87 0.03 FALSE
91 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SNRPC 0.06 0.07 lasso 2 0.07 6.7e-08 12.48 -12.5 1.1e-35 -0.58 1.00 0.00 FALSE
92 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma UHRF1BP1 0.06 0.06 enet 8 0.06 1.3e-07 12.29 9.8 1.2e-22 0.36 0.97 0.01 FALSE
93 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C6orf106 0.04 0.01 blup 68 0.01 2.4e-02 15.80 13.5 1.3e-41 0.88 0.01 0.73 FALSE
94 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPL10A 0.07 0.07 lasso 2 0.06 9.9e-08 -4.11 -5.1 2.7e-07 -0.13 0.41 0.59 FALSE
95 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma UHRF1BP1 0.18 0.28 lasso 5 0.27 1.0e-30 12.48 12.8 2.6e-37 0.61 1.00 0.00 FALSE
96 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma UHRF1BP1 0.08 0.09 blup 71 0.10 2.0e-06 12.48 12.6 1.6e-36 0.59 0.65 0.33 FALSE
97 The Cancer Genome Atlas Brain Lower Grade Glioma C6orf106 0.04 0.05 lasso 4 0.03 8.1e-05 15.86 15.6 5.4e-55 0.99 0.01 0.99 FALSE
98 The Cancer Genome Atlas Brain Lower Grade Glioma UHRF1BP1 0.06 0.05 blup 70 0.04 8.6e-06 4.02 7.8 8.7e-15 0.20 0.97 0.00 FALSE
99 The Cancer Genome Atlas Liver Hepatocellular Carcinoma UHRF1BP1 0.12 0.09 blup 70 0.06 5.6e-04 12.44 10.8 2.2e-27 0.56 0.26 0.13 FALSE
100 The Cancer Genome Atlas Lung Adenocarcinoma C6orf106 0.03 0.03 lasso 3 0.01 7.6e-03 9.20 11.8 3.9e-32 0.79 0.01 0.89 FALSE
101 The Cancer Genome Atlas Lung Adenocarcinoma UHRF1BP1 0.06 0.07 enet 20 0.08 6.4e-10 12.44 11.3 1.2e-29 0.49 1.00 0.00 FALSE
102 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UHRF1BP1 0.04 0.06 blup 70 0.06 1.5e-07 12.48 9.4 7.7e-21 0.36 0.98 0.00 FALSE
103 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C6orf106 0.14 0.07 enet 6 0.06 1.0e-04 15.82 12.7 5.2e-37 0.88 0.01 0.98 FALSE
104 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma UHRF1BP1 0.06 0.07 lasso 1 0.05 1.5e-04 12.29 12.3 1.1e-34 0.56 0.82 0.03 FALSE
105 The Cancer Genome Atlas Pancreatic Adenocarcinoma UHRF1BP1 0.20 0.23 lasso 16 0.25 8.3e-11 12.54 12.3 7.6e-35 0.57 0.99 0.01 FALSE
106 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma UHRF1BP1 0.13 0.09 enet 13 0.10 6.4e-05 12.50 10.8 2.0e-27 0.52 0.31 0.36 TRUE
107 The Cancer Genome Atlas Prostate Adenocarcinoma UHRF1BP1 0.10 0.20 lasso 5 0.19 1.6e-19 12.44 11.8 6.6e-32 0.53 1.00 0.00 FALSE
108 The Cancer Genome Atlas Soft Tissue Sarcoma UHRF1BP1 0.08 0.09 blup 71 0.08 1.0e-05 12.54 12.1 1.1e-33 0.50 0.70 0.12 FALSE
109 The Cancer Genome Atlas Stomach Adenocarcinoma UHRF1BP1 0.08 0.10 lasso 1 0.10 7.1e-08 12.54 12.5 4.8e-36 0.59 0.99 0.00 FALSE
110 The Cancer Genome Atlas Thyroid Carcinoma SNRPC 0.05 0.05 blup 31 0.05 2.9e-05 12.44 -13.6 5.5e-42 -0.67 0.76 0.15 FALSE
111 The Cancer Genome Atlas Thyroid Carcinoma UHRF1BP1 0.07 0.03 blup 71 0.05 2.8e-05 12.44 7.3 3.6e-13 0.20 0.77 0.01 FALSE
112 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma SNRPC 0.09 0.11 lasso 2 0.10 8.1e-04 12.49 -12.5 8.3e-36 -0.59 0.06 0.22 FALSE