[Hub]/) : Traits : Hip circumference : ← →

chr6:33,662,667-36,581,149

Best TWAS P=2.16e-55 · Best GWAS P=4.46e-57 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
74	NTR	Blood	C6orf106	0.03	0.02	lasso	6	0.02	7.2e-07	15.82	15.7	2.2e-55	0.98	0.01	0.99	TRUE
40	GTEx	Esophagus Muscularis	UHRF1BP1	0.42	0.35	enet	48	0.33	1.0e-20	12.49	12.0	3.5e-33	0.46	1.00	0.00	TRUE
20	GTEx	Brain Cortex	C6orf106	0.22	0.07	enet	16	0.10	1.1e-03	15.91	11.8	6.9e-32	0.75	0.01	0.98	TRUE
16	GTEx	Brain Caudate basal ganglia	UHRF1BP1	0.19	0.14	lasso	7	0.12	3.1e-04	12.44	10.9	1.3e-27	0.46	0.40	0.05	TRUE
106	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UHRF1BP1	0.13	0.09	enet	13	0.10	6.4e-05	12.50	10.8	2.0e-27	0.52	0.31	0.36	TRUE
7	GTEx	Adipose Subcutaneous	SNRPC	0.13	0.13	enet	21	0.13	1.2e-10	12.50	-10.6	4.3e-26	-0.39	1.00	0.00	TRUE
22	GTEx	Brain Frontal Cortex BA9	RPS10	0.21	0.08	lasso	3	0.06	8.6e-03	5.53	8.1	5.7e-16	0.26	0.11	0.13	TRUE
31	GTEx	Cells Transformed fibroblasts	RPS10	0.12	0.05	lasso	4	0.06	4.5e-05	8.71	7.8	4.7e-15	0.12	0.98	0.00	TRUE
67	GTEx	Thyroid	RPL10A	0.16	0.09	lasso	11	0.07	8.9e-06	-6.69	-6.7	2.1e-11	-0.16	0.89	0.00	TRUE
57	GTEx	Skin Sun Exposed Lower leg	SRPK1	0.14	0.00	enet	27	0.02	1.2e-02	-3.93	6.0	2.3e-09	0.18	0.24	0.06	TRUE
97	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf106	0.04	0.05	lasso	4	0.03	8.1e-05	15.86	15.6	5.4e-55	0.99	0.01	0.99	FALSE
68	GTEx	Uterus	UHRF1BP1	0.20	0.03	lasso	4	0.07	1.8e-02	12.50	15.1	3.0e-51	0.72	0.08	0.33	FALSE
54	GTEx	Pancreas	C6orf106	0.14	0.11	enet	11	0.13	2.8e-06	13.84	15.0	1.2e-50	0.89	0.02	0.98	FALSE
49	GTEx	Muscle Skeletal	C6orf106	0.08	0.06	lasso	4	0.06	7.1e-07	13.81	-14.8	2.2e-49	-0.88	0.02	0.98	FALSE
48	GTEx	Muscle Skeletal	SNRPC	0.03	0.02	lasso	3	0.02	8.3e-03	12.54	-13.9	8.6e-44	-0.69	0.14	0.63	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PACSIN1	0.07	0.01	lasso	6	0.02	1.1e-03	15.92	13.8	4.5e-43	0.82	0.01	0.97	FALSE
17	GTEx	Brain Caudate basal ganglia	SNRPC	0.19	0.15	lasso	3	0.06	7.7e-03	12.49	-13.7	1.3e-42	-0.65	0.36	0.21	FALSE
30	GTEx	Cells Transformed fibroblasts	UHRF1BP1	0.34	0.32	enet	44	0.31	2.4e-23	12.50	13.7	1.4e-42	0.64	1.00	0.00	FALSE
53	GTEx	Nerve Tibial	C6orf106	0.11	0.07	enet	17	0.07	1.3e-05	15.63	13.6	5.2e-42	0.89	0.01	0.99	FALSE
110	The Cancer Genome Atlas	Thyroid Carcinoma	SNRPC	0.05	0.05	blup	31	0.05	2.9e-05	12.44	-13.6	5.5e-42	-0.67	0.76	0.15	FALSE
93	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf106	0.04	0.01	blup	68	0.01	2.4e-02	15.80	13.5	1.3e-41	0.88	0.01	0.73	FALSE
34	GTEx	Colon Transverse	UHRF1BP1	0.42	0.28	lasso	4	0.28	1.6e-13	12.32	13.4	1.1e-40	0.64	1.00	0.00	FALSE
4	CommonMind	Brain Pre-frontal Cortex	SNRPC	0.10	0.16	lasso	4	0.15	3.6e-18	12.42	-13.3	2.8e-40	-0.65	1.00	0.00	FALSE
37	GTEx	Esophagus Mucosa	UHRF1BP1	0.14	0.15	enet	28	0.17	1.3e-11	12.30	13.2	1.6e-39	0.65	1.00	0.00	FALSE
83	YFS	Blood	UHRF1BP1	0.18	0.34	enet	36	0.34	2.5e-117	12.48	13.0	1.2e-38	0.63	1.00	0.00	FALSE
62	GTEx	Stomach	UHRF1BP1	0.24	0.22	enet	20	0.23	2.2e-11	11.74	13.0	1.8e-38	0.57	1.00	0.00	FALSE
80	ROSMAP	Brain Pre-frontal Cortex	C6orf106	0.30	0.26	bslmm	372	0.33	9.3e-44	15.82	12.9	3.1e-38	0.86	0.01	0.99	FALSE
46	GTEx	Lung	UHRF1BP1	0.17	0.20	enet	22	0.18	4.3e-14	12.48	12.9	4.6e-38	0.57	1.00	0.00	FALSE
61	GTEx	Spleen	UHRF1BP1	0.34	0.21	enet	36	0.17	4.5e-05	12.41	12.9	5.8e-38	0.54	0.62	0.04	FALSE
18	GTEx	Brain Cerebellar Hemisphere	UHRF1BP1	0.22	0.16	lasso	12	0.15	1.0e-04	12.49	12.9	6.4e-38	0.63	0.11	0.75	FALSE
14	GTEx	Artery Tibial	SNRPC	0.06	0.06	lasso	4	0.05	1.3e-04	12.54	-12.8	1.1e-37	-0.61	0.96	0.01	FALSE
6	GTEx	Adipose Subcutaneous	UHRF1BP1	0.30	0.35	enet	28	0.36	1.6e-30	12.50	12.8	1.2e-37	0.60	1.00	0.00	FALSE
60	GTEx	Small Intestine Terminal Ileum	UHRF1BP1	0.20	0.03	lasso	5	0.00	3.4e-01	12.48	12.8	1.7e-37	0.60	0.14	0.10	FALSE
95	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UHRF1BP1	0.18	0.28	lasso	5	0.27	1.0e-30	12.48	12.8	2.6e-37	0.61	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C6orf106	0.29	0.21	bslmm	382	0.23	6.9e-28	15.63	12.8	3.0e-37	0.84	0.01	0.99	FALSE
51	GTEx	Nerve Tibial	UHRF1BP1	0.31	0.31	lasso	6	0.31	3.9e-22	12.50	12.7	4.8e-37	0.58	1.00	0.00	FALSE
103	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf106	0.14	0.07	enet	6	0.06	1.0e-04	15.82	12.7	5.2e-37	0.88	0.01	0.98	FALSE
28	GTEx	Cells EBV-transformed lymphocytes	C6orf106	0.20	0.00	lasso	5	0.00	2.7e-01	14.72	12.7	7.5e-37	0.80	0.03	0.58	FALSE
69	GTEx	Vagina	UHRF1BP1	0.31	0.05	lasso	8	0.04	5.0e-02	12.50	12.7	9.0e-37	0.59	0.09	0.51	FALSE
11	GTEx	Artery Aorta	UHRF1BP1	0.35	0.32	lasso	10	0.30	7.7e-17	12.37	12.7	1.1e-36	0.58	1.00	0.00	FALSE
45	GTEx	Liver	UHRF1BP1	0.13	0.04	lasso	3	0.05	1.8e-02	12.50	12.6	1.2e-36	0.50	0.14	0.23	FALSE
96	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UHRF1BP1	0.08	0.09	blup	71	0.10	2.0e-06	12.48	12.6	1.6e-36	0.59	0.65	0.33	FALSE
79	ROSMAP	Brain Pre-frontal Cortex	SNRPC	0.15	0.27	lasso	4	0.27	4.0e-35	12.54	-12.6	3.4e-36	-0.58	1.00	0.00	FALSE
52	GTEx	Nerve Tibial	SNRPC	0.12	0.10	lasso	4	0.08	1.5e-06	12.50	-12.5	4.2e-36	-0.59	1.00	0.00	FALSE
109	The Cancer Genome Atlas	Stomach Adenocarcinoma	UHRF1BP1	0.08	0.10	lasso	1	0.10	7.1e-08	12.54	12.5	4.8e-36	0.59	0.99	0.00	FALSE
58	GTEx	Skin Sun Exposed Lower leg	SNRPC	0.03	0.04	lasso	2	0.03	1.9e-03	12.50	-12.5	6.0e-36	-0.59	0.55	0.07	FALSE
84	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UHRF1BP1	0.03	0.04	lasso	3	0.04	1.7e-04	12.50	12.5	7.2e-36	0.59	0.32	0.04	FALSE
12	GTEx	Artery Coronary	UHRF1BP1	0.33	0.36	lasso	2	0.35	1.6e-12	12.50	12.5	7.7e-36	0.59	1.00	0.00	FALSE
112	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SNRPC	0.09	0.11	lasso	2	0.10	8.1e-04	12.49	-12.5	8.3e-36	-0.59	0.06	0.22	FALSE
23	GTEx	Brain Putamen basal ganglia	UHRF1BP1	0.20	0.17	lasso	2	0.16	1.5e-04	12.37	12.5	9.8e-36	0.59	0.22	0.19	FALSE
91	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SNRPC	0.06	0.07	lasso	2	0.07	6.7e-08	12.48	-12.5	1.1e-35	-0.58	1.00	0.00	FALSE
38	GTEx	Esophagus Mucosa	SNRPC	0.12	0.10	lasso	2	0.08	4.8e-06	12.41	-12.5	1.3e-35	-0.58	0.99	0.00	FALSE
87	The Cancer Genome Atlas	Breast Invasive Carcinoma	UHRF1BP1	0.04	0.05	lasso	3	0.04	8.4e-09	12.44	12.5	1.4e-35	0.58	1.00	0.00	FALSE
8	GTEx	Adipose Visceral Omentum	UHRF1BP1	0.30	0.34	lasso	3	0.34	3.0e-18	12.32	12.4	1.5e-35	0.58	1.00	0.00	FALSE
5	CommonMind	Brain Pre-frontal Cortex	UHRF1BP1	0.17	0.23	lasso	19	0.22	5.8e-27	12.42	12.4	1.6e-35	0.58	1.00	0.00	FALSE
82	YFS	Blood	SNRPC	0.02	0.03	lasso	5	0.02	3.0e-08	12.51	-12.4	2.9e-35	-0.62	0.98	0.02	FALSE
89	The Cancer Genome Atlas	Colon Adenocarcinoma	UHRF1BP1	0.08	0.11	lasso	12	0.10	2.3e-06	12.54	12.4	3.2e-35	0.58	0.98	0.00	FALSE
90	The Cancer Genome Atlas	Esophageal Carcinoma	UHRF1BP1	0.19	0.20	lasso	10	0.17	5.2e-06	12.32	12.4	3.3e-35	0.58	0.87	0.03	FALSE
25	GTEx	Breast Mammary Tissue (Male)	UHRF1BP1	0.19	0.16	enet	24	0.08	5.6e-03	12.37	12.4	3.4e-35	0.59	0.42	0.09	FALSE
41	GTEx	Esophagus Muscularis	SNRPC	0.09	0.11	lasso	3	0.07	3.8e-05	12.50	-12.4	3.5e-35	-0.59	0.98	0.00	FALSE
65	GTEx	Thyroid	SNRPC	0.07	0.04	lasso	6	0.05	1.6e-04	12.49	-12.4	3.5e-35	-0.57	0.81	0.03	FALSE
88	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	UHRF1BP1	0.07	0.11	lasso	3	0.07	2.6e-04	12.32	12.3	7.4e-35	0.58	0.73	0.05	FALSE
105	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	UHRF1BP1	0.20	0.23	lasso	16	0.25	8.3e-11	12.54	12.3	7.6e-35	0.57	0.99	0.01	FALSE
104	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	UHRF1BP1	0.06	0.07	lasso	1	0.05	1.5e-04	12.29	12.3	1.1e-34	0.56	0.82	0.03	FALSE
35	GTEx	Colon Transverse	C6orf106	0.15	0.05	lasso	1	0.03	1.5e-02	12.28	12.3	1.2e-34	0.61	0.05	0.70	FALSE
86	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNRPC	0.01	0.01	blup	31	0.00	3.0e-02	4.02	-12.3	1.5e-34	-0.56	0.03	0.04	FALSE
70	GTEx	Whole Blood	UHRF1BP1	0.14	0.14	lasso	7	0.14	2.9e-13	12.49	12.2	2.1e-34	0.55	1.00	0.00	FALSE
56	GTEx	Skin Sun Exposed Lower leg	UHRF1BP1	0.19	0.13	enet	33	0.14	2.7e-11	12.50	12.2	5.2e-34	0.53	1.00	0.00	FALSE
108	The Cancer Genome Atlas	Soft Tissue Sarcoma	UHRF1BP1	0.08	0.09	blup	71	0.08	1.0e-05	12.54	12.1	1.1e-33	0.50	0.70	0.12	FALSE
77	ROSMAP	Brain Pre-frontal Cortex	UHRF1BP1	0.16	0.27	lasso	10	0.28	2.7e-36	12.29	12.0	4.0e-33	0.54	1.00	0.00	FALSE
75	NTR	Blood	UHRF1BP1	0.03	0.05	enet	19	0.05	7.4e-15	12.29	12.0	4.6e-33	0.63	1.00	0.00	FALSE
100	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf106	0.03	0.03	lasso	3	0.01	7.6e-03	9.20	11.8	3.9e-32	0.79	0.01	0.89	FALSE
107	The Cancer Genome Atlas	Prostate Adenocarcinoma	UHRF1BP1	0.10	0.20	lasso	5	0.19	1.6e-19	12.44	11.8	6.6e-32	0.53	1.00	0.00	FALSE
24	GTEx	Breast Mammary Tissue	UHRF1BP1	0.34	0.28	enet	46	0.29	4.7e-15	12.32	11.6	4.1e-31	0.51	1.00	0.00	FALSE
10	GTEx	Adrenal Gland	SNRPC	0.13	0.04	lasso	6	0.03	2.7e-02	13.84	-11.6	6.3e-31	-0.57	0.18	0.35	FALSE
13	GTEx	Artery Tibial	UHRF1BP1	0.31	0.43	lasso	11	0.43	4.0e-36	12.50	11.6	6.6e-31	0.52	1.00	0.00	FALSE
101	The Cancer Genome Atlas	Lung Adenocarcinoma	UHRF1BP1	0.06	0.07	enet	20	0.08	6.4e-10	12.44	11.3	1.2e-29	0.49	1.00	0.00	FALSE
26	GTEx	Breast Mammary Tissue (Female)	UHRF1BP1	0.23	0.21	lasso	3	0.20	1.0e-06	12.50	11.3	2.0e-29	0.49	0.80	0.07	FALSE
78	ROSMAP	Brain Pre-frontal Cortex	PACSIN1	0.09	0.00	blup	359	0.02	4.5e-04	15.63	11.3	2.1e-29	0.69	0.01	0.94	FALSE
33	GTEx	Colon Sigmoid	UHRF1BP1	0.44	0.36	lasso	12	0.38	1.8e-14	12.50	10.9	8.4e-28	0.44	1.00	0.00	FALSE
99	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	UHRF1BP1	0.12	0.09	blup	70	0.06	5.6e-04	12.44	10.8	2.2e-27	0.56	0.26	0.13	FALSE
73	METSIM	Adipose	UHRF1BP1	0.16	0.31	enet	30	0.32	1.0e-49	12.54	10.8	2.4e-27	0.49	1.00	0.00	FALSE
19	GTEx	Brain Cerebellum	UHRF1BP1	0.14	0.09	enet	23	0.12	1.5e-04	12.44	10.8	2.6e-27	0.51	0.17	0.28	FALSE
36	GTEx	Esophagus Gastroesophageal Junction	UHRF1BP1	0.47	0.38	enet	22	0.43	7.3e-17	12.51	10.6	3.2e-26	0.50	1.00	0.00	FALSE
43	GTEx	Heart Atrial Appendage	UHRF1BP1	0.13	0.07	enet	17	0.05	1.9e-03	12.54	10.4	3.2e-25	0.38	0.54	0.08	FALSE
66	GTEx	Thyroid	C6orf106	0.09	0.01	enet	29	0.01	1.1e-01	15.86	10.3	5.5e-25	0.75	0.01	0.87	FALSE
71	METSIM	Adipose	C6orf106	0.04	0.02	blup	381	0.02	7.7e-04	9.20	9.9	2.9e-23	0.60	0.03	0.92	FALSE
92	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UHRF1BP1	0.06	0.06	enet	8	0.06	1.3e-07	12.29	9.8	1.2e-22	0.36	0.97	0.01	FALSE
102	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UHRF1BP1	0.04	0.06	blup	70	0.06	1.5e-07	12.48	9.4	7.7e-21	0.36	0.98	0.00	FALSE
47	GTEx	Muscle Skeletal	UHRF1BP1	0.34	0.34	enet	45	0.39	4.3e-40	12.50	9.1	1.1e-19	0.34	1.00	0.00	FALSE
72	METSIM	Adipose	SNRPC	0.05	0.05	lasso	7	0.07	2.9e-11	12.37	-8.4	4.9e-17	-0.32	1.00	0.00	FALSE
44	GTEx	Heart Left Ventricle	UHRF1BP1	0.23	0.12	lasso	7	0.22	1.2e-11	12.32	8.1	3.9e-16	0.33	1.00	0.00	FALSE
27	GTEx	Cells EBV-transformed lymphocytes	UHRF1BP1	0.37	0.08	enet	46	0.11	1.7e-04	12.48	7.9	4.0e-15	0.52	0.20	0.59	FALSE
64	GTEx	Thyroid	UHRF1BP1	0.13	0.06	enet	37	0.08	5.9e-07	3.94	7.8	5.2e-15	0.23	0.99	0.00	FALSE
98	The Cancer Genome Atlas	Brain Lower Grade Glioma	UHRF1BP1	0.06	0.05	blup	70	0.04	8.6e-06	4.02	7.8	8.7e-15	0.20	0.97	0.00	FALSE
9	GTEx	Adrenal Gland	UHRF1BP1	0.32	0.26	enet	33	0.33	1.3e-12	12.50	7.5	9.1e-14	0.29	1.00	0.00	FALSE
42	GTEx	Esophagus Muscularis	NUDT3	0.12	0.00	lasso	7	0.02	3.2e-02	8.98	-7.4	1.1e-13	-0.17	0.13	0.10	FALSE
111	The Cancer Genome Atlas	Thyroid Carcinoma	UHRF1BP1	0.07	0.03	blup	71	0.05	2.8e-05	12.44	7.3	3.6e-13	0.20	0.77	0.01	FALSE
55	GTEx	Skin Not Sun Exposed Suprapubic	UHRF1BP1	0.20	0.10	enet	30	0.15	2.1e-08	12.37	7.1	1.6e-12	0.21	0.99	0.00	FALSE
59	GTEx	Skin Sun Exposed Lower leg	C6orf106	0.09	0.04	enet	25	0.02	4.6e-03	0.49	6.9	4.0e-12	0.56	0.11	0.71	FALSE
21	GTEx	Brain Frontal Cortex BA9	UHRF1BP1	0.18	0.00	lasso	10	0.02	7.3e-02	12.59	6.8	1.3e-11	0.38	0.12	0.10	FALSE
39	GTEx	Esophagus Mucosa	RPL10A	0.14	0.10	enet	17	0.09	2.1e-06	-4.11	-6.6	3.2e-11	-0.15	0.94	0.01	FALSE
85	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS10	0.01	0.01	enet	1	0.01	1.2e-02	6.33	6.3	2.5e-10	0.11	0.17	0.07	FALSE
32	GTEx	Cells Transformed fibroblasts	NUDT3	0.11	0.03	lasso	3	0.02	9.2e-03	7.37	-6.3	3.9e-10	-0.14	0.24	0.03	FALSE
63	GTEx	Testis	RPS10	0.17	0.11	lasso	1	0.04	5.2e-03	5.88	5.9	4.0e-09	0.07	0.30	0.04	FALSE
3	CommonMind	Brain Pre-frontal Cortex	RPL10A	0.21	0.09	enet	30	0.11	2.6e-13	-4.19	-5.8	6.3e-09	-0.12	1.00	0.00	FALSE
29	GTEx	Cells Transformed fibroblasts	DEF6	0.14	0.03	enet	35	0.04	9.7e-04	5.00	-5.7	1.2e-08	-0.17	0.60	0.01	FALSE
15	GTEx	Artery Tibial	RPL10A	0.11	0.08	lasso	2	0.09	1.5e-07	-4.11	-5.7	1.3e-08	-0.13	1.00	0.00	FALSE
76	ROSMAP	Brain Pre-frontal Cortex	TEAD3	0.07	0.03	bslmm	421	0.04	5.6e-06	3.42	-5.5	3.4e-08	-0.26	0.78	0.03	FALSE
81	YFS	Blood	RPS10	0.05	0.05	bslmm	353	0.05	2.2e-16	6.33	5.5	3.4e-08	0.11	1.00	0.00	FALSE
50	GTEx	Muscle Skeletal	RPL10A	0.10	0.05	enet	17	0.04	3.9e-05	-4.19	-5.2	1.6e-07	-0.14	0.72	0.02	FALSE
94	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPL10A	0.07	0.07	lasso	2	0.06	9.9e-08	-4.11	-5.1	2.7e-07	-0.13	0.41	0.59	FALSE