[Hub]/) : Traits : Standing height :

chr6:124,741,508-127,355,237

Best TWAS P=9.76e-94 · Best GWAS P=6.52e-93 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CENPW 0.04 0.06 lasso 10 0.06 2.4e-07 20.31 -20.5 9.8e-94 -0.99 0.02 0.98 TRUE
2 CommonMind Brain Pre-frontal Cortex HEY2 0.15 0.20 lasso 10 0.21 6.7e-25 -7.31 -7.2 4.0e-13 -0.07 0.00 1.00 TRUE
3 GTEx Artery Coronary TPD52L1 0.31 -0.01 enet 19 0.05 7.0e-03 -0.38 -6.1 9.7e-10 -0.15 0.03 0.55 TRUE
4 GTEx Breast Mammary Tissue (Female) HINT3 0.39 -0.01 enet 16 0.08 2.2e-03 -2.72 -5.2 2.5e-07 -0.14 0.13 0.06 TRUE
5 GTEx Esophagus Muscularis HINT3 0.08 0.00 enet 14 0.00 2.9e-01 6.88 -6.2 4.6e-10 -0.11 0.07 0.04 FALSE
6 GTEx Heart Atrial Appendage CENPW 0.17 0.01 enet 15 0.06 1.8e-03 20.19 -12.0 2.0e-33 -0.70 0.03 0.48 FALSE
7 GTEx Pancreas HEY2 0.28 0.11 lasso 3 0.10 3.5e-05 -5.51 -6.0 1.5e-09 -0.06 0.14 0.86 TRUE
8 GTEx Skin Sun Exposed Lower leg HINT3 0.08 0.01 lasso 4 0.03 2.0e-03 -5.46 -6.8 1.1e-11 -0.19 0.22 0.14 TRUE
9 GTEx Testis HEY2 0.31 0.17 lasso 5 0.19 7.4e-09 -6.93 -6.9 5.4e-12 -0.08 0.02 0.98 FALSE
10 GTEx Thyroid HEY2 0.22 0.24 lasso 6 0.23 1.0e-17 -6.93 -7.2 8.2e-13 -0.08 0.02 0.98 FALSE
11 GTEx Vagina CENPW 0.24 -0.01 lasso 8 -0.01 7.9e-01 6.63 8.2 3.1e-16 0.40 0.04 0.06 TRUE
12 METSIM Adipose CENPW 0.02 0.02 blup 189 0.01 8.3e-03 20.19 -14.5 9.9e-48 -0.74 0.03 0.69 FALSE
13 METSIM Adipose HEY2 0.02 0.04 lasso 1 0.02 1.6e-04 -5.43 -5.4 5.5e-08 -0.06 0.03 0.97 FALSE
14 METSIM Adipose NCOA7 0.05 0.05 enet 5 0.05 1.9e-07 5.81 9.2 4.0e-20 0.24 0.95 0.03 FALSE
15 ROSMAP Brain Pre-frontal Cortex HEY2 0.10 0.12 enet 15 0.13 9.8e-17 6.56 -6.6 3.6e-11 -0.06 0.02 0.98 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma TRMT11 0.03 0.03 lasso 1 0.03 3.3e-07 -5.47 5.5 4.4e-08 0.23 0.01 0.99 TRUE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CENPW 0.04 0.05 lasso 5 0.05 2.6e-06 20.17 -19.3 1.1e-82 -0.98 0.02 0.98 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma CENPW 0.04 0.06 blup 35 0.05 9.2e-07 20.09 -19.3 7.7e-83 -0.98 0.03 0.97 FALSE
19 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma HEY2 0.09 0.06 lasso 8 0.06 2.3e-03 -5.51 -5.5 4.0e-08 -0.04 0.03 0.78 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma HEY2 0.03 0.04 lasso 3 0.02 3.8e-03 5.66 -6.0 2.5e-09 -0.07 0.01 0.98 TRUE