Best TWAS P=2.94e-32 · Best GWAS P=1.98e-30 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | SMOC2 | 0.24 | 0.05 | lasso | 6 | 0.05 | 1.7e-04 | 6.5 | -6.1 | 1.0e-09 | 0.33 | 0.87 | 0.01 | FALSE |
| 2 | GTEx | Nerve Tibial | AL391319.1 | 0.20 | 0.04 | lasso | 4 | 0.05 | 9.5e-05 | 6.0 | -5.7 | 9.6e-09 | 0.30 | 0.80 | 0.01 | FALSE |
| 3 | GTEx | Thyroid | AL391319.1 | 0.15 | 0.12 | lasso | 4 | 0.11 | 1.0e-08 | -11.5 | 11.8 | 2.9e-32 | -0.99 | 0.00 | 1.00 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | DACT2 | 0.21 | 0.03 | enet | 59 | 0.09 | 3.1e-11 | -3.4 | 5.7 | 1.1e-08 | -0.12 | 1.00 | 0.00 | TRUE |