[Hub]/) : Traits : Standing height :

chr10:122,989,048-124,889,817

Best TWAS P=3.08e-25 · Best GWAS P=5.29e-23 conditioned to 0.409

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PLEKHA1 0.14 0.06 lasso 2 0.03 2.4e-03 8.6 -8.8 1.6e-18 0.50 0.15 0.79 FALSE
2 GTEx Breast Mammary Tissue PLEKHA1 0.30 0.05 enet 38 0.01 8.6e-02 8.6 -5.5 3.4e-08 0.27 0.09 0.34 FALSE
3 GTEx Colon Sigmoid RP11-500G22.2 0.54 0.00 lasso 20 0.08 1.0e-03 3.6 5.5 3.1e-08 -0.11 0.17 0.05 TRUE
4 GTEx Muscle Skeletal PLEKHA1 0.10 0.04 lasso 3 0.04 8.2e-05 -9.5 -8.9 3.8e-19 0.83 0.02 0.97 FALSE
5 GTEx Nerve Tibial PLEKHA1 0.22 0.23 enet 17 0.19 1.1e-13 8.6 -7.5 7.1e-14 0.41 0.99 0.01 FALSE
6 GTEx Pancreas PLEKHA1 0.29 0.05 lasso 11 0.07 4.7e-04 -6.2 -6.8 1.3e-11 0.77 0.04 0.87 FALSE
7 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -9.9 -10.2 3.0e-24 0.96 0.00 0.99 FALSE
8 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 8.6 -10.4 3.1e-25 0.85 0.01 0.99 TRUE
9 ROSMAP Brain Pre-frontal Cortex PLEKHA1 0.06 0.05 lasso 4 0.05 1.3e-06 -9.5 -9.5 3.0e-21 0.65 0.07 0.93 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma PLEKHA1 0.04 0.05 lasso 2 0.04 4.3e-05 8.6 -8.6 6.8e-18 0.49 0.58 0.27 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ARMS2 0.23 0.20 lasso 2 0.21 7.0e-09 -5.3 -5.6 2.1e-08 0.12 0.93 0.00 FALSE
12 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PLEKHA1 0.08 0.06 blup 103 0.02 4.0e-02 8.6 -8.1 5.8e-16 0.56 0.04 0.54 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma ARMS2 0.06 0.04 blup 71 0.05 4.9e-06 -9.5 -7.1 1.3e-12 0.28 0.12 0.84 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma PLEKHA1 0.08 0.10 lasso 1 0.09 3.5e-09 8.6 -8.6 1.2e-17 0.50 0.97 0.03 FALSE