[Hub]/) : Traits : Standing height :

chr10:119,742,699-122,285,398

Best TWAS P=2.36e-15 · Best GWAS P=1.05e-21 conditioned to 0.000274

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous INPP5F 0.13 0.01 lasso 5 0.01 4.0e-02 -4.28 5.5 4.9e-08 0.26 0.14 0.17 FALSE
2 GTEx Breast Mammary Tissue PRDX3 0.27 0.00 enet 30 0.02 3.9e-02 9.52 5.7 1.6e-08 0.64 0.01 0.91 FALSE
3 GTEx Breast Mammary Tissue (Female) PRDX3 0.34 0.11 enet 31 0.12 1.9e-04 7.01 7.1 1.1e-12 0.64 0.03 0.72 TRUE
4 GTEx Esophagus Gastroesophageal Junction FAM45A 0.24 0.13 enet 51 0.09 2.7e-04 7.49 7.9 2.4e-15 0.36 0.03 0.80 TRUE
5 GTEx Esophagus Gastroesophageal Junction BAG3 0.44 0.32 lasso 8 0.32 2.1e-12 4.36 6.0 2.0e-09 0.26 0.99 0.01 FALSE
6 GTEx Muscle Skeletal PRDX3 0.10 0.10 lasso 3 0.10 4.2e-10 5.73 5.7 1.4e-08 0.14 1.00 0.00 FALSE
7 ROSMAP Brain Pre-frontal Cortex CACUL1 0.12 0.08 lasso 4 0.06 1.2e-08 -6.42 6.3 3.0e-10 0.06 0.97 0.03 FALSE
8 ROSMAP Brain Pre-frontal Cortex PRDX3 0.13 0.02 enet 33 0.06 4.4e-08 0.88 5.6 2.2e-08 0.07 0.69 0.01 FALSE
9 ROSMAP Brain Pre-frontal Cortex GRK5 0.12 0.03 lasso 8 0.06 1.0e-08 5.29 -5.5 4.5e-08 -0.28 0.98 0.01 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PRDX3 0.03 0.00 blup 45 0.01 5.1e-02 -3.71 5.8 7.9e-09 0.13 0.03 0.15 TRUE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C10orf46 0.23 0.04 lasso 4 0.04 8.6e-03 -6.42 6.6 4.8e-11 0.06 0.00 0.87 TRUE
12 The Cancer Genome Atlas Thyroid Carcinoma PRDX3 0.06 0.07 lasso 2 0.05 5.2e-06 5.73 5.7 1.3e-08 0.13 0.94 0.01 FALSE