TWAS
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Usage
Models
Genes
Traits
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Traits
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Standing height
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chr11:127,636,241-129,835,747
Best TWAS P=2.07e-13 · Best GWAS P=4.35e-14 conditioned to 0.242
128M
128.5M
129M
129.5M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
NTR
Blood
FLI1
0.16
0.16
enet
12
0.16
2.9e-49
-7.21
7.3
2.1e-13
-0.91
0.04
0.96
TRUE
1
GTEx
Cells Transformed fibroblasts
ARHGAP32
0.23
0.16
enet
13
0.16
6.0e-12
5.89
5.7
1.1e-08
-0.07
1.00
0.00
TRUE
4
YFS
Blood
ETS1
0.02
0.00
bslmm
616
0.00
9.6e-02
-0.12
5.6
2.4e-08
-0.09
0.05
0.02
FALSE
2
GTEx
Heart Atrial Appendage
ARHGAP32
0.39
0.18
lasso
14
0.13
2.4e-06
5.89
5.3
1.2e-07
-0.05
0.99
0.00
FALSE