Best TWAS P=2.07e-13 · Best GWAS P=4.35e-14 conditioned to 0.242
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | ARHGAP32 | 0.23 | 0.16 | enet | 13 | 0.16 | 6.0e-12 | 5.89 | 5.7 | 1.1e-08 | -0.07 | 1.00 | 0.00 | TRUE |
2 | GTEx | Heart Atrial Appendage | ARHGAP32 | 0.39 | 0.18 | lasso | 14 | 0.13 | 2.4e-06 | 5.89 | 5.3 | 1.2e-07 | -0.05 | 0.99 | 0.00 | FALSE |
3 | NTR | Blood | FLI1 | 0.16 | 0.16 | enet | 12 | 0.16 | 2.9e-49 | -7.21 | 7.3 | 2.1e-13 | -0.91 | 0.04 | 0.96 | TRUE |
4 | YFS | Blood | ETS1 | 0.02 | 0.00 | bslmm | 616 | 0.00 | 9.6e-02 | -0.12 | 5.6 | 2.4e-08 | -0.09 | 0.05 | 0.02 | FALSE |