TWAS hub - ETS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1210	0.0350	0.00067	0.000	0.042	0.018	0.041	0.000	3.6e-01	6.5e-06	2.2e-03	8.3e-06	3.6e-01
2	GTEx	Cells Transformed fibroblasts	0.2090	0.0560	0.00020	0.115	NA	0.074	NA	0.113	5.8e-09	NA	3.2e-06	NA	7.8e-09
3	YFS	Blood	0.0171	0.0084	0.02400	-0.001	0.000	0.000	0.001	-0.001	7.4e-01	2.2e-01	4.9e-01	9.6e-02	7.9e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Blood White Count	5.4	40.1	58.8	3.5	7.7	7.0
Noisy workplace	4.1	5.1	8.2	-2.4	-1.1	-2.9
Schizophrenia vs Biploar Disorder	3.9	5.1	9.1	-1.0	2.3	3.0
Ulcerative Colitis (UC)	3.9	7.4	12.7	2.8	3.6	1.3
Irritable Bowel Disease (IBD)	3.7	8.9	14.3	2.8	3.8	2.1
Ulcerative Colitis	3.3	4.7	10.7	1.8	3.3	-0.1
Medication: Atorvastatin	3.3	4.1	7.2	-2.7	-2.1	0.7
Ever had prostate specific antigen (PSA) test	3.3	3.8	6.0	2.2	2.4	-0.6
Blood Platelet Count	3.1	36.1	99.2	-2.6	10.0	1.6
Supplements: Zinc	2.7	2.9	7.7	-1.0	-2.8	0.3
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.5	8.4	2.8	0.7	2.9
Type 2 Diabetes (T2D) (2018)	2.6	4.9	9.4	0.4	-2.3	3.1
Eye problems/disorders: Diabetes related eye disease	2.6	2.9	6.0	0.5	-1.5	2.4
Ever had stillbirth, spontaneous miscarriage or termination	2.6	2.7	5.2	-1.5	-0.8	-2.3
Eye problems/disorders: None of the above	2.5	2.9	5.5	-0.3	2.3	-1.8
Number of full sisters	2.4	2.9	7.9	2.8	0.4	0.8
Unable to work because of sickness or disability	2.4	3.1	6.8	-1.5	-2.6	-0.5
Height	2.3	44.2	76.4	7.4	-1.3	8.7
Average weekly spirits intake	2.3	2.8	4.0	-2.0	-2.0	0.7
Alcohol intake versus 10 years previously	2.3	3.5	7.5	1.7	-0.5	2.7
Number of full brothers	2.3	2.9	3.9	1.6	-1.5	2.0
Mood swings	2.3	4.2	8.0	-2.8	-0.8	-2.0
Tinnitus: Yes, now most or all of the time	2.3	2.6	5.1	-2.3	-0.4	-1.6
Medication: Metformin	2.2	3.1	5.2	-0.3	-2.3	2.0
Diabetes (self-reported)	2.2	3.4	7.1	0.3	-1.7	2.7
Pack years of smoking	2.2	3.2	7.0	-2.6	-1.2	-1.0
Pack years adult smoking proportion	2.1	3.2	7.2	-2.7	-1.3	-0.7
Diabetes diagnosed by doctor	2.1	3.4	5.6	-0.3	-2.1	2.4
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.5	5.2	-1.1	-2.3	-1.1
Standing height	1.9	18.7	31.1	4.5	-2.1	5.6
Ever highly irritable/argumentative for 2 days	1.9	2.3	4.1	2.0	1.6	-0.5
Crohns Disease (2017)	1.8	3.9	4.5	2.1	2.0	1.8
Primary Biliary Cirrhosis	1.8	2.5	5.4	1.4	-0.3	2.3
Comparative height size at age 10	1.8	9.9	22.4	2.4	-1.4	4.7
Friendships satisfaction	1.8	2.2	3.7	0.7	1.6	-1.9
Fractured/broken bones in last 5 years	1.8	2.3	4.8	-1.1	-2.2	1.0
Basal cell carcinoma (self-reported)	1.8	2.2	4.7	-2.2	-1.3	0.3
Crohns Disease (2012)	1.7	2.7	3.1	1.8	1.7	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	3.9	-1.0	-2.0	-1.4
Heart disease (siblings)	1.7	2.1	2.5	-1.6	-1.5	1.2
Depression (Nagel 2018)	1.6	2.4	6.1	-0.9	-2.5	0.4
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.4	4.6	-2.1	-1.6	-0.5
Father’s age at death	1.6	2.1	4.1	-0.3	2.0	-1.5
Medication: Cholesterol lowering	1.6	2.5	3.1	-1.6	-1.8	1.4
Prostate Cancer	1.5	2.1	4.0	0.6	2.0	1.4
Rheumatoid Arthritis	1.5	2.0	3.8	1.4	0.6	2.0
Frequency of depressed mood in last 2 weeks	1.5	2.1	5.0	-1.2	-2.2	-0.0
Gout (self-reported)	1.5	2.0	5.1	-0.8	-0.5	2.3
Qualifications: College or University degree	1.5	4.7	8.8	3.0	2.1	1.0
Medication: Seretide 50 evohaler	1.5	1.8	3.2	1.8	-1.1	0.9
Risk taking	1.5	2.1	3.5	1.4	1.0	1.9
Suffer from ‘nerves’	1.4	2.2	4.0	-0.6	1.5	2.0
Back pain experienced in last month	1.4	2.1	4.5	-0.4	-2.1	1.3
Arm fat-free mass (left)	1.4	7.0	16.3	0.4	-2.1	4.0
Arm predicted mass (left)	1.4	7.1	16.4	0.1	-2.2	4.0
Age at First Birth	1.3	1.9	4.0	-1.3	-2.0	0.2
Medication: Co-codamol	1.3	1.5	3.6	-0.9	-1.9	0.2
Chronic bronchitis/emphysema (mother)	1.3	1.5	4.4	2.1	0.0	0.4
Bipolar Disorder (2018)	1.2	2.0	3.6	0.5	-1.9	-1.4
Triglycerides	1.2	2.0	4.2	2.1	1.3	-0.3
Trunk predicted mass	1.2	6.6	13.3	0.6	-2.5	3.6
Medication: Ibuprofen	1.2	1.5	2.5	-0.5	-1.3	-1.6
Arm predicted mass (right)	1.2	5.9	12.9	0.3	-2.2	3.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.6	-0.0	1.3	-1.6
Illnesses of siblings: Diabetes	1.2	1.4	4.2	0.0	-0.3	2.0
Wears glasses or contact lenses	1.2	1.4	4.0	-2.0	0.2	-0.3
Bipolar Disorder (2011)	1.1	1.1	2.9	0.6	0.1	-1.7
Systolic blood pressure, automated reading	1.1	3.3	7.7	-2.8	-1.3	-0.7
Sitting height	1.1	7.9	10.6	1.9	-3.1	3.3
Had other major operations	1.1	1.3	2.3	-1.3	0.4	-1.5
Fluid intelligence score	1.1	2.2	6.0	-0.2	0.8	2.4
Trunk fat-free mass	1.1	6.5	12.7	0.5	-2.5	3.6
Arm fat-free mass (right)	1.1	5.8	14.6	0.5	-1.6	3.8
Heart disease (mother)	1.1	1.3	2.8	-1.7	-0.1	1.0
Illness, injury, bereavement, stress in last 2 years	1.1	1.4	2.4	1.6	1.0	-0.9
Commuting to job workplace: Walk	1.1	1.2	2.3	-1.5	-0.4	-1.1
Eye problems/disorders: Cataract	1.1	1.2	2.7	-1.6	-1.0	0.1
Whole body water mass	1.1	6.3	12.6	0.5	-2.4	3.5
Eye problems/disorders: Glaucoma	1.1	1.3	2.9	0.9	-0.4	1.7
Medication: Lisinopril	1.1	1.4	2.4	-1.6	-1.1	0.6
Supplements: Calcium	1.1	1.3	2.7	1.0	-1.6	0.3
Depressed Affect (Nagel 2018)	1.0	2.0	4.8	-2.2	-1.1	0.1
Mouth/teeth dental problems	1.0	1.5	3.6	1.9	-0.9	0.5
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	2.5	-1.0	-1.6	0.3
Impedance of arm (left)	1.0	4.7	8.8	3.0	2.2	-0.7
Length of working week for main job	1.0	1.1	3.0	1.7	0.6	0.2
Overall health rating	1.0	2.2	5.2	-0.9	-0.8	2.3
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.0	-1.4	-1.1	0.7
Whole body fat-free mass	1.0	6.0	12.1	0.6	-2.3	3.5
Mouth/teeth dental problems: Mouth ulcers	1.0	1.7	4.4	-0.6	2.1	-0.4
Hearing aid user	1.0	1.1	3.2	-1.8	0.2	0.1
Ever smoked	1.0	1.7	2.0	1.4	-1.4	1.1
Basal metabolic rate	1.0	5.8	12.2	0.7	-2.1	3.5
Myopia	1.0	1.5	2.9	-1.7	0.0	-1.2
Intelligence (Savage-Jansen 2018)	0.9	2.7	3.3	-1.4	1.6	1.8
Major Depression (MDD)	0.9	1.1	2.4	-0.6	1.6	0.8
Lung FVC	0.9	4.5	13.0	-3.6	-0.7	-0.1
Sensitivity / hurt feelings	0.9	1.5	3.2	1.8	0.2	-1.2
Taking other prescription medications	0.9	1.4	3.0	-1.7	-1.1	0.1
Pain all over the body in last month	0.9	1.0	1.5	-1.1	0.4	1.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.7	0.2	-0.2	1.9
Glaucoma (self-reported)	0.9	1.1	1.6	1.3	0.0	1.3
Pulse wave peak to peak time	0.9	1.0	1.2	1.1	0.9	1.1
Medication: Allopurinol	0.9	1.2	3.4	-0.5	-0.3	1.8
Osteoporosis (self-reported)	0.9	1.1	2.6	0.0	-0.9	1.6
Osteoarthritis (self-reported)	0.9	1.2	2.5	-0.5	0.9	1.6
Smoking status: Current	0.9	1.4	3.8	-0.2	-1.9	0.5
Number of self-reported non-cancer illnesses	0.9	1.5	3.9	0.8	-0.1	2.0
Average weekly champagne plus white wine intake	0.9	1.2	2.5	-1.6	-0.6	-0.9
Guilty feelings	0.9	1.4	1.8	-1.3	1.0	-1.2
Medication: Bendroflumethiazide	0.9	1.4	2.3	-0.1	1.5	-1.3
Impedance of whole body	0.9	4.4	9.1	3.0	2.0	0.0
Coronary Artery Disease (CAD)	0.8	1.0	1.6	-0.0	1.2	1.2
Hypothyroidism (self reported)	0.8	1.9	2.9	-1.7	-0.6	-1.6
Hand grip strength (left)	0.8	2.1	4.5	2.1	-1.3	-0.4
Angina	0.8	1.0	2.6	-0.2	1.6	0.7
Serious illness, injury or assault to yourself	0.8	1.0	1.6	-0.8	-1.3	0.9
Hayfever, allergic rhinitis or eczema	0.8	1.8	3.4	-1.4	-1.9	-0.2
Leg predicted mass (left)	0.8	4.0	7.9	0.6	-1.9	2.8
Hearing difficulty/problems with background noise	0.8	1.2	2.5	-0.2	-1.6	-1.0
Had menopause	0.8	1.0	1.4	-1.2	1.2	0.5
Medication: Simvastatin	0.8	1.2	2.1	-0.5	-1.1	1.5
Illnesses of siblings	0.8	1.1	1.9	0.1	1.1	-1.4
Number of live births	0.8	1.2	1.4	1.2	0.9	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	5.1	2.2	1.0	1.4
Pulse wave reflection index	0.8	1.0	1.1	-1.1	0.9	-1.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	2.3	0.5	1.3	-1.5
Pulse rate, automated reading	0.8	2.7	6.7	-2.6	-0.8	0.9
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.7	0.1	0.2	1.7
Leg fat-free mass (right)	0.8	4.0	7.9	0.8	-1.9	2.8
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.2	-1.5	-0.6	-0.7
Ever taken oral contraceptive pill	0.8	0.9	1.2	-0.8	1.1	-1.0
Illnesses of father: High blood pressure	0.8	1.0	3.0	-1.7	-0.2	0.1
Ever depressed for a whole week	0.8	1.0	2.0	0.6	1.4	0.8
Heart attack/myocardial infarction (self-reported)	0.8	1.0	1.4	1.1	-1.2	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.9	-1.7	0.5	-0.1
Alzheimer’s Disease (in mother)	0.7	0.9	1.6	-1.2	0.4	1.0
HbA1C	0.7	0.7	1.8	-0.6	1.3	-0.3
Neuroticism (2016)	0.7	1.0	1.5	1.1	1.2	-0.6
Cardiovascular Disease	0.7	2.5	6.2	-1.0	-2.5	-0.5
Lung FEV1/FVC ratio	0.7	3.3	6.6	2.6	1.6	-0.9
Chronotype (morning person)	0.7	1.7	4.4	0.8	-2.1	-0.0
Hearing difficulty/problems: Yes	0.7	1.0	1.8	-0.2	1.1	-1.3
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.5	0.9	-0.6	1.2
Leg fat-free mass (left)	0.7	3.8	7.6	0.6	-1.9	2.8
Hand grip strength (right)	0.7	2.0	4.1	2.0	-0.6	1.2
Current tobacco smoking	0.7	1.1	3.0	-0.4	-1.7	0.5
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.3	-0.4	-1.0	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	2.4	-1.6	0.8	-1.2
Medication: Levothyroxine sodium	0.7	1.1	2.7	-1.7	0.4	-0.7
Heart attack	0.7	0.9	1.5	0.9	-1.2	-0.6
Hair/balding pattern: Pattern 4	0.7	1.6	2.4	1.5	1.4	0.7
Loud music exposure frequency	0.7	0.8	2.0	-0.3	1.4	-0.5
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.6	-1.6	-0.8	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	2.2	-0.6	-0.1	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	1.7	0.5	1.3	-0.8
Had major operations	0.7	0.8	1.9	-0.6	-1.4	0.4
Medication: Aspirin	0.7	0.9	1.5	-1.2	-1.1	-0.2
Supplements: Vitamin C	0.7	0.8	1.5	-0.6	-0.7	-1.2
Illnesses of father: Heart disease	0.7	1.0	2.7	-1.7	-0.4	-0.2
Qualifications: nursing, teaching	0.7	1.1	1.7	1.3	0.3	-1.2
Breast cancer (self-reported)	0.7	0.9	2.0	-1.4	-0.8	0.2
Medication: Gliclazide	0.7	0.8	1.7	0.8	0.2	-1.3
Illnesses of father: None of the above (group 1)	0.7	0.9	2.2	1.5	0.4	-0.6
Leg predicted mass (right)	0.7	4.0	7.7	0.7	-1.9	2.8
High cholesterol (Self-reported)	0.7	1.2	1.7	-1.3	-0.4	1.3
Cholesterol lowering medication	0.7	1.1	2.0	-0.1	-1.1	1.4
Worry (Nagel 2018)	0.6	1.3	2.6	0.0	1.1	1.6
Fasting Glucose	0.6	0.7	1.9	0.5	0.0	-1.4
HDL Cholesterol	0.6	1.0	1.4	-1.1	-0.7	1.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.9	-1.4	-0.1	0.5
Heel T-Score	0.6	5.1	12.2	-3.5	1.7	-0.4
Waist Hip Ratio (WHR)	0.6	2.8	8.4	-2.9	0.3	-0.2
Allergy or Eczema	0.6	1.5	2.7	-1.3	-1.7	-0.5
Number of treatments/medications taken	0.6	1.1	2.2	-0.7	-0.8	1.5
Multivitamins +/- minerals	0.6	0.7	1.1	-1.0	-0.5	0.9
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.0	0.1	-1.4	-0.2
Weight	0.6	3.2	7.9	0.6	-1.1	2.8
Impedance of arm (right)	0.6	2.6	5.9	2.4	1.3	-0.6
Pulse rate	0.6	1.1	1.4	-0.9	-1.2	1.0
Happiness	0.6	0.8	2.2	-0.3	1.5	-0.2
Mouth/teeth dental problems: Dentures	0.6	1.0	1.7	-1.3	-1.0	0.4
Medication: Lansoprazole	0.6	0.7	1.3	-0.4	0.8	1.1
Exposure to tobacco smoke at home	0.6	0.7	1.3	-0.6	-0.6	-1.2
Medication: Paracetamol	0.6	1.0	2.8	-0.1	1.7	0.4
Forced vital capacity (FVC), Best measure	0.6	2.2	3.4	1.9	0.7	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.2	-0.6	-1.1	1.0
Neck or shoulder pain in last month	0.6	0.8	2.4	0.0	-1.6	-0.3
Angina (self-reported)	0.6	0.8	1.9	-0.2	1.4	0.6
Long-standing illness, disability or infirmity	0.6	0.9	2.0	-0.0	-0.8	1.4
Diastolic blood pressure, automated reading	0.6	1.9	3.1	-1.8	-1.6	0.2
Pain experienced in last month	0.6	1.0	1.6	-0.1	1.3	-1.2
Alzheimer’s Disease (in father)	0.5	0.6	1.3	0.5	-1.1	0.5
Alzheimer’s Disease (including proxy)	0.5	0.8	1.0	-0.7	-0.9	1.0
Age when periods started (menarche)	0.5	1.3	2.8	1.0	1.7	-0.1
Impedance of leg (left)	0.5	2.6	5.7	2.4	1.3	0.6
Hair/balding pattern: Pattern 2	0.5	0.6	1.7	-0.3	1.3	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	2.0	-0.6	1.1	-1.4
Hip circumference	0.5	2.2	3.2	0.7	-1.7	1.8
Lung cancer (father)	0.5	0.6	1.1	1.0	0.4	0.7
Pulse wave Arterial Stiffness index	0.5	0.6	0.8	-0.7	-0.9	-0.7
Breastfed as a baby	0.5	0.6	1.5	0.3	-1.2	0.5
Peak expiratory flow (PEF)	0.5	1.2	1.7	1.1	-1.3	-0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.9	0.7	0.0	-1.4
Blood clot in the leg (DVT)	0.5	0.6	1.8	-1.4	0.2	0.2
High blood pressure (siblings)	0.5	0.7	1.9	0.4	-0.0	1.4
Age at first live birth	0.5	0.9	2.5	-0.1	-0.5	-1.6
Financial situation satisfaction	0.5	0.6	1.3	1.1	0.7	-0.1
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.1	-1.0	-0.9	0.3
Medication: Paracetamol	0.5	0.7	1.4	0.6	1.2	0.7
Irritability	0.5	0.8	1.6	-1.3	-0.7	-0.5
Age started oral contraceptive pill	0.5	0.6	1.7	-0.1	1.3	-0.4
Commuting to job workplace: Cycle	0.5	0.6	1.4	1.2	0.4	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.2	-1.1	0.6	-0.5
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.3	-0.3	0.6	1.5
Ovarian Cancer	0.4	0.6	1.0	0.3	-1.0	-0.7
Schizophrenia (2014)	0.4	0.8	1.5	-0.6	1.2	0.8
Blood Red Count	0.4	4.3	11.4	-0.7	-1.0	3.4
Smoking Status	0.4	0.9	2.5	-0.4	-1.6	0.4
Respiratory disease	0.4	0.9	2.3	-0.7	-0.2	1.5
Diabetes (father)	0.4	0.5	1.4	-1.2	-0.3	-0.3
Diabetes (mother)	0.4	0.5	1.2	-1.1	0.6	0.2
Impedance of leg (right)	0.4	2.2	4.7	2.2	1.1	0.8
Maternal smoking around birth	0.4	0.5	0.9	-0.0	0.9	-0.9
Fed-up feelings	0.4	0.8	1.1	-0.9	-1.0	-0.7
Medication: Atenolol	0.4	0.5	1.0	0.2	-0.7	-1.0
Past tobacco smoking	0.4	0.7	1.1	-1.0	0.4	-1.1
Qualifications: None of the above	0.4	0.9	1.4	-1.0	-0.4	1.2
Medication: Ramipril	0.4	0.5	0.8	0.9	-0.6	0.4
Time employed in main current job	0.4	0.4	1.2	-0.2	1.1	-0.1
Worrier / anxious feelings	0.4	0.7	2.1	-0.3	1.5	-0.0
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	3.3	1.8	-0.2	0.9
Health satisfaction	0.4	0.5	1.0	1.0	-0.5	0.6
Medication: Blood pressure	0.4	0.7	1.2	-0.4	-0.9	1.1
Chest pain or discomfort	0.4	0.5	1.1	-1.0	0.3	-0.7
Average weekly red wine intake	0.4	0.7	1.3	0.2	0.8	-1.2
Ever had bowel cancer screening	0.4	0.5	1.4	0.2	-1.2	0.2
Medication for cholesterol	0.4	0.6	0.9	-0.7	0.9	-0.7
Medication: Aspirin	0.4	0.5	0.9	-0.9	-0.8	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	1.8	-1.3	0.6	-0.5
Miserableness	0.4	0.6	1.7	-1.3	0.4	0.1
Mother’s age at death	0.4	0.5	1.3	-0.5	1.2	-0.0
Commuting to job workplace: Public transport	0.4	0.5	0.6	-0.7	0.6	0.8
Medication: Blood pressure	0.4	0.8	2.2	1.5	0.3	-0.3
Number of operations (self-reported)	0.4	0.6	1.0	-1.0	-0.3	-0.8
Average weekly beer plus cider intake	0.4	0.5	1.1	-0.6	-1.1	-0.2
Neuroticism (Nagel 2018)	0.3	0.6	1.9	-1.4	-0.1	0.1
Schizophrenia (2018)	0.3	0.6	0.7	-0.7	0.9	0.8
Relative age of first facial hair	0.3	0.6	0.9	1.0	0.5	0.8
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.6	-0.8	0.7	0.5
Ever had hysterectomy (womb removed)	0.3	0.4	0.9	-0.4	-1.0	0.2
Medication for hormone replacement therapy	0.3	0.4	0.8	-0.4	-0.2	0.9
Average weekly fortified wine intake	0.3	0.3	0.5	-0.5	0.2	-0.7
Waist circumference	0.3	1.2	1.7	-1.3	-0.6	1.2
Number of incorrect matches in round	0.3	0.4	1.3	-0.0	1.1	0.1
Financial difficulties in last 2 years	0.3	0.4	1.0	-0.5	1.0	-0.2
Allergy	0.3	0.7	1.0	1.0	1.0	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.2	-0.2	-0.6	1.1
Asthma	0.3	0.5	1.1	-0.2	0.7	1.1
Illnesses of mother	0.3	0.4	0.8	0.3	-0.9	-0.5
Tense / ‘highly strung’	0.3	0.5	0.6	-0.6	-0.8	0.7
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.9	0.1	0.9	-0.6
Birth weight	0.3	0.6	0.8	-0.9	-0.7	-0.8
Wheeze or whistling in the chest in last year	0.3	0.5	1.2	-1.1	-0.4	0.0
Leg fat mass (right)	0.3	1.1	1.7	-1.1	-0.7	1.3
Age at last live birth	0.3	0.5	1.1	0.5	-1.1	-0.2
Family relationship satisfaction	0.3	0.4	1.0	0.5	1.0	-0.2
Leg pain on walking	0.3	0.4	0.9	-0.1	-0.9	0.6
Loneliness, isolation	0.3	0.4	0.7	0.1	-0.9	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.9	0.1	-0.4	0.9
Mineral and other dietary supplements	0.3	0.4	0.6	-0.1	0.8	0.8
Alcohol drinker status: Never	0.3	0.4	0.9	-1.0	0.5	-0.1
Leg fat mass (left)	0.3	1.1	2.1	-0.9	-0.6	1.5
Mean Putamen Volume	0.2	0.2	0.6	0.8	-0.2	-0.2
Lupus	0.2	0.2	0.7	-0.1	-0.8	0.0
Neuroticism	0.2	0.4	1.3	-0.2	1.1	-0.1
Severe depression (siblings)	0.2	0.2	0.4	0.5	-0.6	-0.3
Townsend deprivation index at recruitment	0.2	0.3	0.6	-0.4	-0.1	-0.8
Relative age voice broke	0.2	0.4	0.5	0.6	-0.7	0.5
Stomach or abdominal pain in last month	0.2	0.3	0.4	0.6	-0.5	0.5
Supplements: Glucosamine	0.2	0.2	0.4	-0.5	-0.6	0.0
High blood pressure (mother)	0.2	0.2	0.5	0.4	-0.7	-0.3
Body mass index (BMI)	0.2	1.0	2.8	-1.7	-0.3	0.1
Trunk fat mass	0.2	0.8	2.2	-0.2	-0.2	1.5
Nervous feelings	0.2	0.3	0.7	-0.2	0.8	-0.4
Forced vital capacity (FVC)	0.2	0.8	1.1	1.1	-0.7	0.9
Neuroticism score	0.2	0.3	0.8	-0.4	0.9	-0.0
Hair/balding pattern: Pattern 3	0.2	0.4	0.7	-0.2	-0.6	-0.8
Arm fat mass (right)	0.2	0.8	2.1	-0.5	-0.2	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.4	-0.6	0.5	-0.2
Birth weight of first child	0.2	0.4	0.8	0.5	-0.1	-0.9
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.6	-0.4	0.5	-0.7
Headache pain in last month	0.2	0.4	0.9	0.1	1.0	-0.5
Medication: Amlodipine	0.2	0.2	0.4	0.4	-0.7	0.1
Leg fat percentage (right)	0.2	0.7	1.9	-1.4	0.2	0.2
Comparative body size at age 10	0.2	0.5	1.2	-0.5	0.2	-1.1
Number of children fathered	0.2	0.2	0.6	0.3	0.3	0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.4	-0.6	-0.0	-0.6
Medication for pain relief, constipation, heartburn	0.2	0.3	0.4	0.7	0.4	-0.6
Medication: Omeprazole	0.2	0.3	0.7	-0.3	0.9	0.2
Whole body fat mass	0.2	0.9	2.4	-0.4	-0.2	1.5
Hypertension (Self-reported)	0.2	0.7	0.8	-0.9	-0.7	-0.8
Smoking status: Previous	0.2	0.3	0.5	0.7	0.4	0.6
Asthma (self-reported)	0.2	0.4	0.6	-0.3	0.7	0.8
Arm fat mass (left)	0.2	0.7	1.7	-0.6	-0.3	1.3
Bipolar Disorder or Schizophrenia	0.1	0.1	0.3	-0.2	-0.5	-0.3
Reaction Time	0.1	0.2	0.5	-0.3	-0.7	0.1
Breast Cancer	0.1	0.2	0.6	-0.4	-0.1	-0.8
Body Mass Index (BMI) (2010)	0.1	0.1	0.1	-0.1	-0.3	-0.3
Blood Eosinophil Count	0.1	1.0	1.4	-1.1	-0.7	-1.2
BMI	0.1	0.7	1.3	-1.1	-0.9	0.1
Systolic Blood Pressure	0.1	0.7	1.2	-0.9	-1.1	-0.3
Tanning	0.1	1.6	2.8	1.7	-1.1	-1.0
Vitamin and mineral supplements	0.1	0.1	0.1	0.4	0.3	0.0
Trunk fat percentage	0.1	0.3	0.4	-0.4	0.5	0.6
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.4	0.6	-0.2	0.1
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.5	-0.0	-0.4
Alcohol usually taken with meals	0.1	0.1	0.2	-0.5	-0.0	-0.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.3	0.1	0.6	0.2
Arm fat percentage (right)	0.1	0.3	0.4	-0.6	0.6	0.4
Falls in the last year	0.1	0.2	0.5	-0.7	0.2	0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.6	0.8	-0.3	-0.3
Depression (self-reported)	0.1	0.1	0.1	-0.3	-0.1	0.3
Prospective memory result	0.1	0.2	0.5	0.1	0.0	0.7
Body fat percentage	0.1	0.5	0.5	-0.7	0.6	0.7
Exposure to tobacco smoke outside home	0.1	0.2	0.3	0.1	0.4	-0.6
Worry too long after embarrassment	0.1	0.1	0.3	0.5	0.1	0.2
Emphysema/chronic bronchitis	0.1	0.1	0.3	0.1	-0.5	0.3
Migraine (self-reported)	0.1	0.1	0.1	-0.4	0.2	-0.3
Mean time to correctly identify matches	0.1	0.3	0.4	-0.6	-0.4	0.5
Alcohol intake frequency.	0.1	0.1	0.3	0.2	0.3	0.5
Knee pain experienced in last month	0.1	0.2	0.3	-0.6	-0.3	0.5
Arm fat percentage (left)	0.1	0.3	0.6	-0.6	0.8	0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.3	0.3	0.5	0.0
Leg fat percentage (left)	0.1	0.5	1.4	-1.2	0.3	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.3	-0.0	0.5	0.5
Alcohol drinker status: Previous	0.1	0.1	0.4	-0.0	-0.6	0.1
LDL Cholesterol	0.0	0.1	0.1	0.2	0.0	0.4
Hair Pigment	0.0	0.8	2.2	-0.3	0.1	1.5
High blood pressure	0.0	0.1	0.3	-0.0	-0.3	-0.5
Chronic bronchitis/emphysema (father)	0.0	0.1	0.1	-0.3	-0.3	-0.0
Shortness of breath walking on level ground	0.0	0.0	0.1	0.0	0.3	0.2

Hub : Genes

ETS1

Models

Trait associations