[Hub]/) : Traits : Standing height :

chr12:47,805,753-52,362,786

Best TWAS P=4.8e-15 · Best GWAS P=6.09e-15 conditioned to 0.0203

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DIP2B 0.11 0.10 enet 16 0.13 2.6e-15 7.37 7.8 4.8e-15 0.81 0.05 0.95 TRUE
2 GTEx Adipose Subcutaneous ATF1 0.07 0.05 enet 14 0.04 3.1e-04 -4.52 -5.6 2.2e-08 -0.68 0.71 0.25 FALSE
3 GTEx Artery Tibial RP4-605O3.4 0.04 0.01 lasso 4 0.00 3.2e-01 6.88 6.6 3.2e-11 0.53 0.10 0.58 FALSE
4 GTEx Brain Caudate basal ganglia LIMA1 0.18 0.12 lasso 5 0.07 3.9e-03 7.24 6.8 1.3e-11 0.45 0.07 0.56 FALSE
5 GTEx Brain Cerebellar Hemisphere PFKM 0.29 0.09 enet 14 0.06 1.5e-02 -6.28 7.0 3.4e-12 0.07 0.02 0.93 TRUE
6 GTEx Brain Cerebellar Hemisphere RP4-605O3.4 0.18 0.12 enet 14 0.10 1.5e-03 7.00 6.5 6.7e-11 0.49 0.07 0.55 FALSE
7 GTEx Brain Cerebellum PFKM 0.20 0.07 lasso 10 0.07 4.2e-03 -5.74 5.7 1.3e-08 0.09 0.07 0.75 FALSE
8 GTEx Brain Putamen basal ganglia CERS5 0.29 0.12 enet 36 0.21 1.2e-05 7.13 6.8 7.1e-12 0.43 0.24 0.54 FALSE
9 GTEx Cells Transformed fibroblasts SMARCD1 0.08 0.07 enet 5 0.07 9.3e-06 7.59 -7.4 1.6e-13 -0.50 0.01 0.99 FALSE
10 GTEx Heart Atrial Appendage CERS5 0.14 0.03 lasso 6 0.02 4.2e-02 7.00 6.3 2.2e-10 0.54 0.15 0.74 FALSE
11 GTEx Muscle Skeletal ATF1 0.09 0.06 lasso 5 0.07 5.0e-07 -4.64 -5.3 1.0e-07 -0.64 0.60 0.40 FALSE
12 GTEx Muscle Skeletal TFCP2 0.05 0.01 lasso 2 0.00 1.2e-01 -5.25 -5.2 1.7e-07 -0.35 0.57 0.01 FALSE
13 GTEx Nerve Tibial CERS5 0.31 0.28 enet 20 0.36 2.2e-26 7.00 6.9 5.3e-12 0.64 0.25 0.75 FALSE
14 GTEx Nerve Tibial RP4-605O3.4 0.11 0.00 lasso 3 0.00 1.7e-01 6.88 5.6 1.9e-08 0.52 0.06 0.64 FALSE
15 GTEx Prostate CERS5 0.19 0.08 lasso 4 0.02 1.2e-01 6.93 7.0 1.7e-12 0.62 0.08 0.18 FALSE
16 GTEx Skin Not Sun Exposed Suprapubic ZNF641 0.15 0.11 enet 30 0.10 3.1e-06 4.19 5.5 3.1e-08 0.11 0.98 0.01 FALSE
17 GTEx Skin Sun Exposed Lower leg SMARCD1 0.07 0.02 lasso 2 0.03 1.4e-03 -3.90 -6.0 2.4e-09 -0.49 0.06 0.82 FALSE
18 GTEx Skin Sun Exposed Lower leg ZNF641 0.21 0.03 enet 17 0.08 6.5e-07 -6.23 6.7 2.1e-11 0.10 0.45 0.54 FALSE
19 GTEx Testis SMARCD1 0.22 0.10 enet 22 0.10 2.6e-05 6.64 -7.1 1.6e-12 -0.51 0.07 0.91 FALSE
20 GTEx Testis SLC11A2 0.17 0.13 enet 11 0.12 9.2e-06 -5.52 -6.7 1.9e-11 -0.42 0.69 0.22 FALSE
21 GTEx Testis CERS5 0.12 0.06 lasso 6 0.07 4.0e-04 7.00 7.1 1.7e-12 0.64 0.13 0.38 FALSE
22 GTEx Testis ZNF641 0.16 0.07 lasso 2 0.10 4.2e-05 -5.75 6.8 1.0e-11 0.10 0.21 0.54 FALSE
23 GTEx Thyroid CERS5 0.09 0.04 lasso 9 0.04 3.7e-04 -3.85 5.3 1.0e-07 0.45 0.66 0.30 FALSE
24 GTEx Thyroid ZNF641 0.16 0.06 enet 26 0.13 2.0e-10 -0.99 5.9 4.3e-09 0.08 0.83 0.16 FALSE
25 GTEx Thyroid RP11-579D7.2 0.14 0.02 enet 31 0.02 7.3e-03 -5.74 5.6 2.5e-08 0.08 0.01 0.94 FALSE
26 GTEx Whole Blood ATF1 0.07 0.09 lasso 4 0.07 3.5e-07 6.25 6.3 3.7e-10 0.78 0.93 0.07 FALSE
27 GTEx Whole Blood RP4-605O3.4 0.04 0.04 lasso 4 0.01 1.5e-02 6.93 7.2 8.5e-13 0.58 0.05 0.82 FALSE
28 METSIM Adipose DAZAP2 0.06 0.05 lasso 4 0.05 1.8e-07 -5.07 -5.3 1.4e-07 0.07 1.00 0.00 TRUE
29 NTR Blood ATF1 0.06 0.07 enet 35 0.07 4.0e-21 7.66 6.8 7.3e-12 0.78 0.02 0.98 FALSE
30 YFS Blood ATF1 0.05 0.07 lasso 9 0.07 2.0e-21 7.62 7.6 2.4e-14 0.93 0.02 0.98 FALSE
31 YFS Blood LIMA1 0.04 0.06 enet 31 0.06 3.5e-19 -4.18 -5.5 4.5e-08 -0.65 1.00 0.00 FALSE
32 The Cancer Genome Atlas Breast Invasive Carcinoma C12orf62 0.01 0.00 blup 47 0.00 4.6e-02 -3.44 -5.8 8.2e-09 -0.45 0.02 0.56 FALSE
33 The Cancer Genome Atlas Breast Invasive Carcinoma SMARCD1 0.02 0.03 lasso 1 0.03 3.7e-06 7.24 -7.2 4.6e-13 -0.47 0.02 0.98 FALSE
34 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C12orf62 0.02 0.01 blup 47 0.01 1.7e-02 -3.50 -5.7 9.3e-09 -0.43 0.02 0.60 FALSE
35 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ZNF641 0.04 0.03 lasso 1 0.03 5.9e-04 -5.74 5.7 9.6e-09 0.08 0.03 0.49 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIMA1 0.08 0.10 blup 59 0.10 1.8e-11 6.53 -6.9 6.7e-12 -0.66 0.05 0.95 FALSE
37 The Cancer Genome Atlas Brain Lower Grade Glioma ATF1 0.03 0.04 lasso 1 0.04 6.3e-05 7.61 -7.6 2.8e-14 -0.94 0.01 0.99 FALSE
38 The Cancer Genome Atlas Lung Squamous Cell Carcinoma LETMD1 0.03 0.02 lasso 4 0.02 1.9e-03 -5.10 5.2 2.4e-07 0.35 0.02 0.72 FALSE
39 The Cancer Genome Atlas Prostate Adenocarcinoma LETMD1 0.03 0.03 blup 44 0.02 7.4e-03 -5.25 5.8 5.0e-09 0.38 0.01 0.87 FALSE