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chr13:20,282,946-21,990,467

Best TWAS P=2.56e-14 · Best GWAS P=3.25e-15 conditioned to 3.26e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	YFS	Blood	IL17D	0.02	0.02	blup	482	0.01	1.8e-04	-5.5	-7.6	2.6e-14	-0.43	0.64	0.13	TRUE
6	GTEx	Cells EBV-transformed lymphocytes	CRYL1	0.27	0.00	lasso	11	0.00	3.4e-01	-5.5	-7.5	6.8e-14	-0.57	0.04	0.46	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IFT88	0.04	0.03	blup	83	0.03	2.2e-04	5.4	7.3	2.1e-13	0.58	0.03	0.91	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	IFT88	0.05	0.00	blup	85	0.02	2.1e-03	4.7	7.3	2.2e-13	0.51	0.02	0.49	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	IFT88	0.11	0.10	blup	86	0.09	3.5e-10	5.5	7.2	5.4e-13	0.64	0.03	0.97	FALSE
13	METSIM	Adipose	IFT88	0.11	0.07	bslmm	543	0.07	3.9e-10	5.3	6.1	1.0e-09	0.56	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	IFT88	0.06	0.04	blup	86	0.03	1.4e-07	4.3	5.7	1.4e-08	0.48	0.84	0.15	FALSE
8	GTEx	Esophagus Muscularis	IFT88	0.38	0.26	lasso	4	0.25	1.4e-15	5.5	5.5	3.3e-08	0.61	1.00	0.00	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	IFT88	0.12	0.08	lasso	5	0.05	1.4e-03	5.5	5.5	3.6e-08	0.63	0.37	0.15	FALSE
5	GTEx	Brain Cerebellum	IFT88	0.29	0.24	lasso	1	0.22	3.3e-07	5.5	5.5	4.0e-08	0.62	0.75	0.12	FALSE
12	GTEx	Skin Sun Exposed Lower leg	IFT88	0.10	0.06	lasso	4	0.06	1.7e-05	5.5	5.5	4.5e-08	0.63	0.95	0.02	FALSE
3	GTEx	Artery Aorta	IFT88	0.25	0.23	enet	16	0.22	2.3e-12	5.3	5.4	6.7e-08	0.62	1.00	0.00	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	IFT88	0.42	0.20	lasso	8	0.23	5.7e-09	5.3	5.4	6.9e-08	0.60	0.99	0.00	FALSE
9	GTEx	Heart Atrial Appendage	IFT88	0.36	0.28	lasso	4	0.28	4.7e-13	5.5	5.4	7.2e-08	0.60	1.00	0.00	FALSE
10	GTEx	Heart Left Ventricle	IFT88	0.27	0.27	lasso	7	0.26	2.3e-14	5.3	5.3	9.9e-08	0.63	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	IFT88	0.27	0.33	lasso	11	0.34	1.4e-42	5.3	5.3	1.1e-07	0.61	1.00	0.00	FALSE
4	GTEx	Artery Tibial	IFT88	0.27	0.17	enet	40	0.19	1.4e-14	5.5	5.2	2.2e-07	0.53	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	IFT88	0.25	0.18	lasso	6	0.18	2.9e-14	5.3	5.1	2.7e-07	0.60	1.00	0.00	FALSE