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chr13:32,305,370-34,048,051

Best TWAS P=9.38e-13 · Best GWAS P=1.44e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	N4BP2L2	0.13	0.10	lasso	3	0.09	1.1e-05	7.0	7.1	9.4e-13	0.99	0.01	0.99	TRUE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	N4BP2L2	0.04	0.03	blup	69	0.02	9.4e-04	7.0	6.9	6.4e-12	0.97	0.01	0.98	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	CG030	0.04	0.01	lasso	3	0.02	2.1e-04	7.0	-6.8	1.0e-11	-0.97	0.00	0.99	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	N4BP2L2	0.02	0.02	lasso	2	0.01	1.4e-03	6.8	6.8	1.1e-11	0.97	0.01	0.95	FALSE
12	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	N4BP2L2	0.04	0.04	lasso	2	0.03	1.5e-04	6.8	6.7	1.5e-11	0.97	0.01	0.98	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	N4BP2L2	0.12	0.14	enet	7	0.16	1.1e-15	6.0	6.7	2.4e-11	0.98	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	N4BP2L2	0.10	0.10	lasso	4	0.11	5.2e-12	7.0	6.5	6.3e-11	0.97	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	PDS5B	0.02	0.01	blup	78	0.02	1.2e-02	6.7	-6.4	1.5e-10	-0.91	0.02	0.86	FALSE
13	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CG030	0.08	0.04	blup	38	0.04	1.4e-03	6.9	-6.4	1.7e-10	-0.94	0.00	0.89	FALSE
1	GTEx	Adipose Subcutaneous	RP11-298P3.4	0.09	0.01	lasso	7	0.00	1.9e-01	5.8	6.3	3.7e-10	0.86	0.04	0.90	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	N4BP2L2	0.03	0.02	lasso	4	0.02	2.8e-03	6.8	6.2	5.3e-10	0.88	0.02	0.93	FALSE
4	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CG030	0.06	0.01	blup	38	0.03	6.0e-04	-4.2	-6.0	1.5e-09	-0.84	0.01	0.83	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CG030	0.07	0.02	lasso	4	0.03	2.4e-04	6.9	-5.7	1.3e-08	-0.85	0.01	0.69	FALSE
14	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CG030	0.12	0.02	blup	38	0.03	3.1e-02	7.0	-5.7	1.6e-08	-0.84	0.00	0.59	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	CG030	0.06	0.01	blup	38	0.02	1.9e-03	-4.1	-5.6	1.7e-08	-0.84	0.01	0.90	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	N4BP2L2	0.06	0.03	lasso	3	0.05	1.0e-05	-3.4	5.4	8.5e-08	0.82	0.01	0.98	FALSE
3	YFS	Blood	PDS5B	0.03	0.04	lasso	1	0.03	1.4e-11	5.3	5.3	8.9e-08	0.80	0.25	0.75	FALSE