Best TWAS P=1.13e-07 · Best GWAS P=4.73e-07 conditioned to 0.435
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | SPG20 | 0.27 | 0.11 | lasso | 4 | 0.06 | 1.3e-03 | -5 | 5.3 | 1.1e-07 | -0.94 | 0.02 | 0.96 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMAD9 | 0.06 | 0.02 | enet | 9 | 0.03 | 5.2e-07 | 5 | 5.2 | 2.1e-07 | 0.04 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SMAD9 | 0.08 | 0.03 | enet | 6 | 0.05 | 2.9e-06 | 5 | 5.3 | 1.4e-07 | 0.04 | 0.00 | 1.00 | TRUE |