Hub : Genes

SPG20

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Liver	0.2400	0.0870	0.00390	0.039	NA	0.010	NA	0.050	3.0e-02	NA	1.7e-01	NA	1.6e-02
2	GTEx	Nerve Tibial	0.0874	0.0371	0.00500	0.112	NA	0.089	NA	0.096	2.4e-08	NA	7.2e-07	NA	2.7e-07
3	GTEx	Pancreas	0.2680	0.0820	0.00026	0.114	NA	0.047	NA	0.062	1.6e-05	NA	4.6e-03	NA	1.3e-03
4	GTEx	Skin Not Sun Exposed Suprapubic	0.1910	0.0650	0.00052	0.000	NA	0.006	NA	-0.004	3.3e-01	NA	1.4e-01	NA	6.8e-01
5	GTEx	Thyroid	0.1020	0.0430	0.00390	0.001	NA	0.008	NA	0.006	2.6e-01	NA	7.8e-02	NA	1.1e-01
6	GTEx	Whole Blood	0.0880	0.0330	0.00150	0.023	NA	0.003	NA	0.003	2.9e-03	NA	1.5e-01	NA	1.6e-01
7	TCGA	Breast Invasive Carcinoma	0.0155	0.0095	0.00330	0.005	0.004	0.006	NA	0.003	2.2e-02	0.0350	2.0e-02	NA	6.6e-02
8	TCGA	Prostate Adenocarcinoma	0.0423	0.0295	0.00640	0.005	0.020	0.004	NA	0.016	9.7e-02	0.0030	1.2e-01	NA	8.2e-03
9	TCGA	Rectum Adenocarcinoma	0.1660	0.0840	0.00250	0.146	0.092	0.101	NA	0.127	2.7e-04	0.0037	2.4e-03	NA	6.7e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.3	0.5	1.8	-0.4	-0.3	-0.4	-1.3	-1.2	0.3	0.4	-0.5	-0.5
Bipolar Disorder or Schizophrenia	0.1	0.3	0.9	0.2	0.8	0.2	-1.0	-0.6	0.4	0.5	0.3	-0.3
Depressed Affect (Nagel 2018)	0.6	1.3	4.1	0.6	0.8	-1.4	1.3	-0.5	2.0	0.2	-0.8	-1.4
Depression (Nagel 2018)	0.9	1.4	9.2	0.7	0.3	-1.2	3.0	0.7	0.8	0.5	-0.2	-0.3
Intelligence (Savage-Jansen 2018)	0.3	1.1	3.2	0.6	1.5	1.0	-0.2	1.8	0.1	-1.4	0.4	0.9
Neuroticism (Nagel 2018)	0.6	1.3	4.0	1.4	0.6	-1.2	1.4	-0.2	2.0	-0.1	-0.3	-1.4
Schizophrenia (2018)	0.2	0.3	1.6	0.6	1.3	0.5	-0.0	0.0	0.3	0.3	0.8	0.1
Schizophrenia vs Biploar Disorder	2.1	2.8	9.3	-1.8	-1.9	-1.1	3.0	1.0	1.5	0.6	-1.4	-1.7
Worry (Nagel 2018)	0.7	1.5	4.1	1.6	0.6	-1.2	1.1	-0.1	2.0	-1.0	-0.0	-1.6
Alzheimer’s Disease (in mother)	0.6	0.7	1.7	0.3	0.5	-0.6	-0.1	1.3	0.6	-0.9	-1.2	-1.0
Alzheimer’s Disease (in father)	0.3	0.3	1.6	-0.3	0.1	-0.0	1.3	0.9	-0.4	-0.4	-0.2	-0.1
Alzheimer’s Disease (including proxy)	0.5	0.8	2.5	0.1	0.3	-0.5	0.8	1.6	0.4	-1.2	-0.9	-1.0
Crohns Disease (2017)	2.2	4.7	12.6	-1.8	-3.6	-2.3	2.1	1.4	1.9	1.9	-2.1	-1.7
Irritable Bowel Disease (IBD)	1.1	2.6	4.7	-1.5	-2.2	-1.6	1.0	1.1	1.8	1.6	-2.0	-1.5
Ulcerative Colitis (UC)	0.1	0.2	0.5	-0.2	0.3	0.4	-0.7	0.7	0.2	-0.1	-0.6	-0.1
Major Depression (MDD)	3.7	4.4	8.8	-1.2	-2.4	-2.4	3.0	0.9	1.4	2.6	-2.1	-2.0
Reaction Time	0.3	0.5	1.2	1.1	1.0	0.6	0.5	0.3	-0.9	-0.3	0.8	0.5
Verbal and Numeric Reasoning (VNR)	0.5	1.3	3.5	0.2	0.9	-0.5	0.9	1.8	1.9	-1.0	-1.0	-1.0
Breast Cancer	0.9	2.2	3.6	-1.8	-1.2	-1.3	0.9	-1.6	1.6	1.4	-1.2	-1.9
Ovarian Cancer	0.3	0.4	1.1	-0.7	-0.8	-0.3	0.9	0.1	0.6	0.1	-1.1	-0.5
Prostate Cancer	0.1	0.1	0.5	-0.7	-0.1	0.5	0.5	-0.0	-0.4	0.2	0.2	0.3
Age at First Birth	1.5	2.2	5.6	0.4	1.2	1.6	1.5	0.5	-2.2	-2.4	0.9	1.1
Bipolar Disorder (2011)	1.6	1.6	4.5	1.1	1.9	0.1	-2.1	-2.1	0.5	-0.4	-0.1	0.2
Body Mass Index (BMI) (2010)	0.3	0.4	0.8	-0.6	0.1	-0.9	0.4	-0.7	-0.2	0.6	-0.9	-0.8
Coronary Artery Disease (CAD)	0.6	0.8	4.1	-0.2	0.5	0.9	-0.4	-1.0	-0.6	-0.3	0.3	2.0
Crohns Disease (2012)	2.3	3.6	6.2	-1.0	-2.5	-2.3	1.3	1.9	2.5	1.6	-1.8	-1.8
Mean Putamen Volume	1.0	1.1	2.5	-0.3	-1.6	-1.0	1.4	1.6	0.3	0.6	-0.2	-1.2
Fasting Glucose	0.4	0.5	3.5	0.3	-0.5	-0.6	0.2	-0.5	1.9	-0.1	0.4	-0.3
HbA1C	0.6	0.7	1.6	-0.0	-1.2	-1.1	-0.2	-0.4	1.0	0.7	-0.6	-1.1
HDL Cholesterol	0.5	0.9	1.7	-0.8	-1.2	-1.0	1.1	-1.3	0.7	0.9	-0.7	-0.2
LDL Cholesterol	0.1	0.1	0.4	-0.3	0.0	0.2	0.7	-0.3	-0.4	0.4	0.5	-0.0
Lupus	0.4	0.6	2.2	-0.8	-0.4	0.3	1.1	1.5	0.5	0.4	-0.4	0.6
Neuroticism (2016)	0.4	0.5	1.9	1.4	0.9	0.3	0.4	0.3	0.7	-0.2	0.9	0.5
Primary Biliary Cirrhosis	0.8	1.1	2.4	-1.6	-1.5	-0.8	0.2	-0.1	0.6	1.5	-1.3	-0.5
Rheumatoid Arthritis	0.3	0.4	1.6	-0.1	0.4	-0.0	1.3	0.9	0.3	0.7	-0.2	0.3
Schizophrenia (2014)	0.1	0.1	0.2	0.2	0.4	-0.2	0.1	0.1	0.5	0.5	0.5	-0.3
Triglycerides	0.4	0.6	1.4	-1.1	-0.7	-0.5	-0.7	0.6	1.2	0.6	-0.6	-0.9
Type 2 Diabetes (T2D) (2012)	2.9	3.3	7.5	-2.7	-1.6	-1.9	-1.1	-0.3	1.3	2.2	-2.2	-1.8
Ulcerative Colitis	0.6	0.8	2.5	-0.8	-0.9	-0.7	0.7	1.0	0.6	0.5	-1.6	-0.9
Blood Eosinophil Count	0.0	0.3	1.3	-0.2	0.1	-0.7	0.1	-0.3	0.5	0.5	-0.2	-1.2
Blood Platelet Count	1.2	13.6	22.7	-3.2	-3.5	-4.6	2.9	-1.2	3.9	3.7	-4.1	-4.8
Blood Red Count	0.1	1.4	4.0	1.0	0.2	1.1	-0.3	-1.0	-1.7	-1.4	0.6	2.0
Blood White Count	0.3	2.2	3.9	-0.5	-0.9	-1.9	1.4	-1.5	1.9	0.9	-1.4	-2.0
Heel T-Score	0.4	3.5	6.2	-2.4	-2.5	-2.4	0.1	0.7	0.8	1.6	-2.0	-2.5
BMI	1.2	7.1	14.9	-2.9	-3.9	-3.2	1.3	0.9	1.9	2.7	-2.7	-3.1
Height	1.5	28.6	52.4	5.4	3.8	7.2	-0.2	0.5	-6.7	-5.7	6.6	6.3
Waist Hip Ratio (WHR)	0.2	0.9	2.3	1.4	0.9	-0.4	1.5	0.7	0.7	-0.3	-0.1	-1.3
Systolic Blood Pressure	0.2	0.8	4.6	0.7	0.6	-0.3	-0.7	-2.1	0.4	-0.5	-0.5	-0.5
Smoking Status	0.2	0.4	1.3	1.1	0.8	-0.2	0.7	0.1	-0.1	-0.4	-1.0	-0.5
Allergy or Eczema	0.9	2.3	5.4	-0.8	-0.7	-2.0	0.6	-0.8	2.3	2.1	-1.0	-1.8
Cardiovascular Disease	0.7	2.3	4.5	-0.8	-0.9	-2.1	1.5	-0.6	2.0	1.4	-1.5	-1.9
Hypothyroidism (self reported)	0.3	0.6	2.0	-0.3	-1.4	-0.5	0.6	-1.2	0.4	0.9	-0.5	-0.5
Respiratory disease	0.3	0.6	2.5	0.4	0.9	-0.3	1.1	-0.1	1.6	0.4	-0.3	-0.3
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.0	-0.1	-0.2	-1.0	-1.0	-0.2	0.6	-0.5	-0.4	-0.4
Lung FEV1/FVC ratio	0.2	1.1	3.4	-0.4	-0.3	-1.3	0.0	1.7	1.0	-0.4	-1.8	-0.7
Lung FVC	0.2	1.2	5.2	-0.1	0.0	-1.1	-0.2	-2.3	0.6	1.7	-0.4	-1.1
Neuroticism	0.8	1.9	7.7	0.1	0.3	-1.8	1.6	-0.7	2.8	0.2	-0.7	-1.4
Chronotype (morning person)	0.9	2.1	4.4	1.2	0.6	1.9	-0.3	-0.4	-1.8	-2.1	1.8	1.5
Hair Pigment	0.1	2.6	7.7	-1.8	-1.2	-1.7	1.1	-0.5	1.6	0.7	-2.8	-1.8
Tanning	0.1	1.1	2.4	-0.5	-1.2	-1.2	-0.5	-0.8	1.6	1.4	-0.9	-0.7
Hand grip strength (left)	0.8	2.1	5.5	0.4	-0.5	2.0	-0.9	1.5	-1.8	0.4	2.4	1.7
Number of treatments/medications taken	1.9	3.3	7.8	-0.4	-0.7	-2.8	2.1	0.0	2.1	1.6	-2.3	-2.2
Average weekly spirits intake	1.9	2.3	4.5	1.9	1.6	1.2	-2.1	-1.8	-1.0	-1.5	0.8	1.2
Sensitivity / hurt feelings	0.4	0.7	2.2	-0.2	-0.3	-1.1	1.4	-0.6	0.6	0.1	-1.5	-0.7
Frequency of depressed mood in last 2 weeks	1.2	1.6	11.4	0.2	0.3	-0.9	3.4	0.5	1.1	0.6	-0.2	-0.8
Hearing difficulty/problems: Yes	1.2	1.9	6.2	0.6	-0.2	1.4	-2.0	-2.5	-1.2	-0.8	0.2	1.4
Relative age of first facial hair	0.8	1.7	3.2	0.9	1.8	1.1	-1.5	-0.6	-1.1	-1.8	1.0	1.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.7	-0.1	-0.9	-1.6	0.6	-0.5	0.3	0.9	-1.0	-1.4
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.6	0.9	-0.9	-0.3	0.2	-0.1	1.2	0.6	-0.5	-0.9
Ever had hysterectomy (womb removed)	1.1	1.2	4.1	0.5	0.3	1.4	0.3	-2.0	-1.8	-0.5	0.6	0.7
Systolic blood pressure, automated reading	0.1	0.3	0.7	0.3	-0.2	-0.4	-0.6	-0.7	-0.1	-0.2	-0.8	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.1	1.0	0.7	0.2	-0.6	-0.2	-0.5	-0.3	0.6	0.1
Angina	0.8	1.0	3.3	-0.3	0.4	-1.1	-0.8	-1.8	1.3	0.6	-0.8	-1.1
Medication for hormone replacement therapy	1.2	1.3	4.0	-0.2	-1.1	-1.3	1.4	2.0	0.1	0.3	-0.9	-1.5
Vitamin and mineral supplements	0.6	0.9	1.8	1.3	0.8	1.4	-1.0	-0.7	-0.6	-0.8	0.6	0.6
Supplements: Zinc	0.5	0.6	2.7	0.3	-0.5	0.2	0.0	-0.6	-0.4	0.7	1.6	1.2
Medication: Co-codamol	0.9	1.0	3.6	0.4	0.0	-1.2	0.3	-0.6	1.5	0.9	0.3	-1.9
Medication: Metformin	0.5	0.7	1.6	-1.3	-1.2	-0.7	-0.4	1.0	0.1	0.1	-0.8	-0.6
Diabetes (father)	0.4	0.5	2.5	0.2	0.2	-0.1	0.6	1.6	0.4	0.4	0.8	-0.6
Diabetes (mother)	0.2	0.3	1.5	0.1	-0.2	-0.3	0.2	-0.3	1.2	0.1	-0.1	-1.0
Severe depression (siblings)	0.9	1.0	2.5	-0.6	-1.3	-0.9	0.7	-0.3	1.3	1.6	-1.0	-0.5
Pack years adult smoking proportion	0.7	1.0	3.5	0.8	1.0	-1.0	1.9	-0.8	1.0	0.2	-0.7	-1.0
Impedance of leg (right)	1.3	6.1	12.1	3.1	3.5	2.6	-2.2	-0.3	-1.1	-2.7	2.5	2.5
Leg fat-free mass (left)	0.2	0.9	2.9	-0.9	-1.7	0.7	0.6	0.7	-1.5	-0.3	0.1	0.4
Trunk fat percentage	0.3	1.2	5.7	-1.3	-2.4	-0.6	-0.4	-0.8	0.3	0.2	-1.3	-0.8
Hand grip strength (right)	1.6	4.4	11.1	2.3	0.7	2.6	-0.7	0.8	-3.0	-0.9	3.3	2.1
Townsend deprivation index at recruitment	1.1	1.5	7.7	1.4	2.8	0.5	-0.6	0.2	-0.8	-0.9	1.1	0.9
Current tobacco smoking	0.2	0.4	2.1	0.7	-0.2	-0.5	0.9	0.3	0.3	-0.0	-1.4	-0.2
Average weekly fortified wine intake	1.3	1.6	2.4	-1.4	-1.6	-1.3	0.2	1.5	1.0	0.9	-1.5	-1.4
Maternal smoking around birth	0.7	1.0	3.7	0.5	-0.0	0.5	1.9	1.9	0.5	-0.1	1.0	-0.2
Fed-up feelings	0.2	0.3	1.5	0.5	0.4	-0.2	1.2	-0.5	0.6	-0.4	0.1	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	11.6	-0.5	0.0	-1.7	3.4	1.0	1.0	0.5	-1.2	-1.1
Relative age voice broke	0.2	0.3	0.9	-0.4	0.0	0.5	-1.0	-0.4	-0.2	0.2	0.8	0.7
Taking other prescription medications	0.5	0.8	1.9	-0.4	-1.0	-1.4	1.0	-0.5	0.5	0.6	-1.3	-0.6
Age when periods started (menarche)	0.4	1.1	2.0	-0.8	-0.1	-1.4	0.3	-1.1	1.0	1.1	-1.4	-1.2
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.5	1.5	-0.1	1.1	0.4	-0.0	-1.6	-0.7	1.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.7	0.1	0.1	0.2	-1.3	-0.1	0.1	0.9	0.4	0.3
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.6	-0.2	-1.6	-0.6	0.8	0.5	0.9	0.5	-0.5	-0.4
Qualifications: CSEs or equivalent	2.0	2.6	6.4	1.7	1.4	2.0	-0.3	0.7	-1.8	-0.5	2.5	2.0
Serious illness, injury or assault to yourself	0.2	0.3	0.7	0.3	0.5	-0.5	-0.7	0.1	0.8	-0.0	-0.8	-0.5
High blood pressure	1.0	2.8	5.3	-1.1	-1.9	-2.3	1.4	0.2	1.7	1.3	-1.8	-2.3
Hayfever, allergic rhinitis or eczema	1.0	2.1	6.2	-0.1	-0.3	-2.0	0.6	-0.3	2.5	2.0	-0.5	-2.1
Multivitamins +/- minerals	0.1	0.2	0.7	-0.8	-0.1	-0.8	0.4	-0.2	0.2	-0.1	-0.2	-0.1
Stomach or abdominal pain in last month	2.0	2.5	6.3	-0.2	-0.6	-1.8	2.3	-0.1	1.4	2.5	-0.1	-2.3
Supplements: Glucosamine	1.3	1.8	5.8	-2.4	-1.1	-1.5	-0.7	-0.1	0.8	0.9	-2.1	-0.5
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	5.2	-0.9	-0.8	-1.7	1.6	0.0	1.5	1.5	-1.1	-2.3
Medication: Atenolol	0.3	0.4	1.1	0.4	0.1	0.4	0.2	-0.7	-0.9	-0.9	0.0	1.1
Medication: Levothyroxine sodium	0.2	0.4	1.3	-0.0	-1.0	-0.0	0.0	-1.1	-0.9	0.1	-0.8	-0.1
Sitting height	1.9	13.8	23.3	3.4	2.5	4.8	-1.8	-0.1	-4.8	-4.4	4.4	4.3
Chronic bronchitis/emphysema (father)	0.6	0.7	4.5	0.6	-0.2	0.5	-1.0	-2.1	-0.5	-0.1	0.1	0.6
High blood pressure (mother)	0.3	0.5	1.8	0.1	-0.6	0.3	-0.6	1.3	0.9	0.0	0.7	-0.4
Body mass index (BMI)	1.2	5.1	11.9	-2.7	-3.5	-2.4	0.9	0.5	1.4	2.1	-2.8	-2.5
Impedance of leg (left)	1.2	5.8	10.5	3.1	3.2	2.5	-2.3	-0.6	-1.2	-2.5	2.5	2.6
Leg predicted mass (left)	0.2	0.9	2.9	-0.9	-1.7	0.7	0.6	0.9	-1.6	-0.3	0.2	0.4
Trunk fat mass	0.2	1.0	5.5	-1.3	-2.3	-0.4	-0.3	-0.4	-0.2	0.0	-1.0	-0.6
Waist circumference	1.0	3.5	6.8	-2.2	-2.6	-1.9	1.5	0.6	0.9	1.6	-2.3	-2.3
Number of incorrect matches in round	1.0	1.7	3.8	0.0	0.0	-1.9	-0.4	-1.9	2.0	1.3	-1.0	-1.2
Past tobacco smoking	0.3	0.6	1.7	-0.6	-0.3	1.0	-0.4	-0.2	-1.0	0.3	1.3	0.9
Alcohol usually taken with meals	0.7	1.2	5.2	-0.7	-2.3	0.0	1.2	0.4	-0.7	1.3	0.6	0.6
Nervous feelings	0.7	1.3	4.8	1.1	1.0	-1.3	0.7	0.1	2.2	0.1	0.1	-1.5
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.1	7.9	-0.3	-0.2	-1.8	2.8	0.4	1.7	1.1	-0.6	-1.6
Hearing difficulty/problems with background noise	0.5	0.8	2.4	-0.8	-1.6	-0.9	0.8	-0.9	0.6	0.8	-0.9	-0.7
Hair/balding pattern: Pattern 2	1.3	1.6	3.2	-0.6	-1.8	-1.2	0.5	-1.6	1.2	1.6	-1.1	-1.2
Had menopause	0.4	0.5	1.7	1.3	0.1	1.0	0.8	-0.5	-0.7	0.2	0.6	0.6
Had other major operations	0.2	0.2	0.5	-0.1	-0.3	-0.6	0.5	-0.2	0.7	-0.2	-0.7	-0.3
Forced vital capacity (FVC)	0.6	2.2	4.1	1.5	1.1	1.5	-1.1	-1.4	-1.8	-1.1	2.0	1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.4	0.5	-0.4	-0.6	-0.5	-1.2	0.9	1.0	-0.1	-0.5
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	2.8	0.5	1.5	-0.8	1.7	1.6	1.1	0.8	-0.3	-1.0
Qualifications: None of the above	0.8	1.7	6.3	2.5	0.7	0.3	-1.2	-1.2	-1.1	0.4	1.8	0.7
Financial difficulties in last 2 years	0.5	0.7	1.5	0.9	0.2	0.9	0.8	0.9	-0.9	-0.2	1.2	0.7
Mouth/teeth dental problems	0.3	0.4	1.0	-0.0	0.7	1.0	-0.9	0.3	-0.2	0.3	1.0	0.3
Heart attack	0.5	0.6	3.5	-0.0	-0.7	-0.8	0.3	-1.9	0.4	0.6	-0.5	-0.2
Allergy	0.7	1.5	6.8	-0.4	-0.5	1.3	-0.6	0.2	-2.6	-1.1	0.4	1.6
Pain all over the body in last month	3.2	3.4	10.1	-0.9	0.1	-2.6	-0.5	-0.0	3.2	0.6	-2.4	-2.5
Diabetes (self-reported)	0.3	0.4	0.9	0.4	0.2	-0.8	-0.2	0.5	0.7	-1.0	-0.7	-0.7
Hayfever/allergic rhinitis (self-reported)	2.6	3.5	9.0	-1.4	-0.7	-2.4	-0.2	0.6	3.0	2.1	-1.8	-2.5
Medication: Ramipril	1.6	2.1	4.2	-1.4	-1.6	-1.5	0.3	-1.0	1.2	1.7	-2.1	-1.5
Medication: Simvastatin	1.6	2.4	5.6	-2.3	-1.3	-1.3	-0.5	-1.1	1.5	2.4	-1.7	-0.9
Fluid intelligence score	0.2	0.4	1.4	0.2	0.6	-0.1	1.2	1.0	0.6	-0.4	-0.2	-0.2
Illnesses of siblings	0.3	0.4	1.2	0.4	0.4	-1.1	0.0	0.2	1.1	-0.4	-0.5	-0.2
Neuroticism score	0.3	0.6	2.2	0.8	0.2	-0.4	1.1	0.2	1.5	-0.6	0.3	-0.6
Weight	0.2	0.9	5.1	-1.2	-2.3	0.0	0.3	0.5	-1.0	0.1	-0.7	-0.3
Impedance of arm (right)	0.7	3.2	6.1	1.7	2.4	2.1	-1.0	-1.2	-1.2	-2.5	1.5	1.9
Arm fat percentage (right)	0.9	3.4	8.2	-2.2	-2.9	-1.8	0.6	-0.0	1.4	1.4	-2.3	-2.1
Trunk fat-free mass	0.3	1.5	5.6	0.5	-0.0	1.7	0.0	1.1	-2.4	-0.9	1.4	1.2
Hip circumference	0.7	3.1	11.1	-2.5	-3.3	-1.5	1.0	0.4	0.1	1.3	-1.9	-1.6
Time employed in main current job	0.8	0.9	2.3	0.3	-0.5	0.8	-1.5	-0.5	-1.0	-1.3	0.4	1.3
Alcohol intake versus 10 years previously	0.5	0.7	1.9	-0.6	0.3	-1.0	-0.0	0.5	0.8	0.7	-1.4	-1.2
Father’s age at death	0.7	0.9	5.2	0.4	0.8	-0.3	0.9	-2.3	0.8	0.6	0.2	0.3
Worrier / anxious feelings	0.5	1.0	2.8	-0.2	-0.9	-1.1	1.2	-0.3	1.7	0.0	-0.7	-1.5
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	6.0	-0.9	-0.2	-1.7	2.4	1.4	1.6	1.1	-1.9	-1.4
Falls in the last year	0.1	0.2	0.7	0.4	0.1	0.4	0.3	0.8	0.3	-0.7	0.3	-0.1
Hair/balding pattern: Pattern 3	0.4	0.6	2.7	-0.8	-0.2	-0.2	-0.1	1.6	-0.8	0.8	-0.3	-0.5
Number of live births	0.4	0.6	1.7	1.3	0.7	0.3	-0.3	-1.0	1.1	0.4	0.6	-0.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.2	1.0	0.9	0.7	-0.9	-0.8	-0.8	-1.0	1.1	0.8
Pulse rate	1.4	2.4	4.0	-1.4	-1.7	-1.3	1.1	2.0	1.9	0.4	-1.6	-2.0
Happiness	1.0	1.2	5.0	-0.3	0.3	-0.8	2.2	1.0	1.0	-0.4	-1.2	-1.3
Noisy workplace	0.6	0.7	2.7	0.3	-0.6	0.9	-0.9	-1.2	0.3	0.3	0.1	1.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.6	0.5	1.9	0.4	1.1	1.2	0.7	-0.9	0.1	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.8	-0.7	-0.7	0.4	-1.4	0.8	-0.9	0.1	0.4	0.3
Mouth/teeth dental problems: Dentures	0.5	0.8	5.3	-0.6	-0.7	-0.5	-0.2	-2.3	0.8	0.0	-0.5	-0.4
Asthma	0.3	0.5	2.0	0.3	0.7	-0.6	0.6	-0.0	1.4	0.1	-0.5	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.2	-0.5	-1.1	-0.2	0.9	0.7	-0.0	0.9	-0.4	-0.4
Medication: Cholesterol lowering	0.6	0.9	1.9	-0.8	-0.6	-1.2	0.4	-0.8	1.2	0.6	-1.4	-1.1
Depression (self-reported)	4.7	5.6	9.3	-3.0	-2.2	-3.0	2.2	-0.0	1.8	2.7	-2.7	-2.2
Medication: Lansoprazole	4.2	4.8	13.1	-1.1	-0.6	-3.0	0.2	-0.7	3.6	2.4	-2.6	-2.5
Prospective memory result	1.2	1.5	4.3	1.1	0.3	1.2	-0.4	-2.1	-1.3	0.5	1.7	1.2
Lung cancer (father)	0.3	0.3	0.8	0.7	-0.7	-0.1	-0.4	-0.1	-0.9	0.9	0.3	0.5
Illnesses of mother	2.0	2.5	6.6	1.1	1.4	1.9	-0.1	-0.9	-2.6	-1.1	1.1	2.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.2	-0.0	0.3	0.2	0.0	-0.4	-0.3	0.1	0.4	0.3
Pulse wave Arterial Stiffness index	1.3	1.5	9.1	-0.1	-0.7	-0.1	1.2	3.0	0.4	-0.9	-0.7	-0.8
Impedance of arm (left)	0.7	3.3	6.7	1.8	2.1	2.1	-1.0	-1.8	-1.2	-2.6	1.3	2.0
Arm fat mass (right)	0.4	1.5	5.9	-1.5	-2.4	-0.9	0.6	0.3	0.4	0.6	-1.5	-1.3
Trunk predicted mass	0.3	1.7	6.1	0.5	-0.0	1.7	0.0	1.2	-2.5	-0.9	1.4	1.3
Standing height	1.5	15.1	28.1	3.4	2.5	5.3	-1.3	-0.4	-5.1	-4.4	4.7	4.5
Length of working week for main job	0.7	0.7	3.3	-0.5	-0.3	-0.4	-0.8	-1.8	-0.6	-0.4	-1.2	0.2
Exposure to tobacco smoke at home	0.3	0.3	1.0	0.0	-0.1	0.5	1.0	0.8	-0.2	0.5	0.7	-0.0
Breastfed as a baby	2.9	3.7	8.2	-2.4	-2.4	-1.8	-0.1	-1.3	1.7	2.9	-1.7	-1.6
Tense / ‘highly strung’	0.2	0.3	1.2	1.1	0.4	-0.0	0.5	0.1	0.1	-0.6	1.0	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	3.1	-0.2	0.2	-1.8	1.4	0.7	1.3	1.3	-0.9	-1.0
Hair/balding pattern: Pattern 4	0.1	0.3	1.2	-1.1	0.3	-0.4	0.1	0.6	0.7	0.4	-0.4	-0.4
Birth weight of first child	0.8	1.5	5.2	0.4	0.6	2.3	0.0	-0.4	-1.2	-0.7	1.7	1.6
Peak expiratory flow (PEF)	0.1	0.2	0.6	0.3	0.8	-0.1	-0.7	-0.3	0.1	-0.6	0.0	0.0
Pulse wave reflection index	0.2	0.3	1.2	0.7	0.8	-0.1	-0.3	-0.1	1.1	-0.4	0.1	0.0
Ever highly irritable/argumentative for 2 days	1.5	1.8	2.7	-1.3	-0.9	-1.5	1.2	0.9	1.4	1.6	-1.4	-1.5
Loud music exposure frequency	0.7	0.7	3.7	0.7	1.9	0.6	0.9	-0.4	0.5	-0.5	0.0	0.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.8	-0.9	0.0	1.1	1.3	1.0	-0.6	-0.7	0.4	0.0
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	4.2	0.3	-0.1	-2.1	0.6	0.1	0.8	0.3	-1.5	-1.5
Blood clot in the leg (DVT)	0.5	0.7	4.6	0.3	0.2	-0.8	0.5	0.1	2.1	-0.3	-0.6	-0.3
Medication: Paracetamol	0.7	1.2	2.8	-0.0	-0.9	-1.4	1.1	1.2	0.6	1.7	-0.4	-1.2
Headache pain in last month	0.4	0.7	2.5	0.1	0.1	0.2	1.6	1.6	0.7	0.7	0.0	-0.7
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.5	0.4	0.6	1.0	-0.4	0.7	-1.1	-0.2	1.2	1.0
Glaucoma (self-reported)	0.7	0.8	3.6	-0.5	-1.9	-0.1	-0.7	-0.0	-1.4	0.4	0.5	0.4
Gout (self-reported)	0.6	0.8	2.7	1.6	1.0	0.0	-1.1	-0.4	0.6	-1.3	0.4	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.9	0.3	-0.7	0.1	0.4	-1.4	-0.4	-0.1	-0.5	-0.0
Medication: Amlodipine	0.4	0.5	2.1	-0.2	-0.4	-0.3	1.1	-0.3	-0.1	-0.2	-0.9	-1.5
Medication: Ventolin 100micrograms inhaler	0.2	0.3	2.0	0.0	0.4	0.1	1.4	-0.4	-0.2	0.5	-0.4	-0.0
Birth weight	3.4	7.3	14.0	2.3	2.3	3.7	-1.7	-0.3	-2.7	-2.9	3.5	3.1
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.9	0.4	0.6	-0.2	-0.7	-0.9	0.4	-0.2	0.0	-0.0
High blood pressure (siblings)	0.2	0.3	0.7	-0.7	-0.8	0.5	0.6	0.3	-0.4	0.7	0.1	-0.1
Forced vital capacity (FVC), Best measure	0.2	0.9	1.6	0.8	0.9	1.0	-0.0	-0.9	-1.3	-0.7	1.3	0.8
Body fat percentage	0.6	2.2	7.7	-1.9	-2.8	-1.3	-0.2	-0.4	0.7	0.8	-1.9	-1.4
Leg fat percentage (right)	1.1	4.0	8.8	-2.3	-3.0	-2.2	0.1	0.4	1.5	1.6	-2.7	-2.2
Arm fat-free mass (right)	0.2	1.0	3.7	0.1	-0.9	1.2	-0.1	1.1	-1.9	-0.5	0.9	1.0
Exposure to tobacco smoke outside home	0.2	0.2	0.8	-0.1	0.5	-0.3	-0.7	-0.5	0.1	-0.9	-0.1	0.4
Comparative body size at age 10	0.1	0.4	1.5	0.2	0.2	0.2	0.7	0.8	-0.4	-1.2	-0.3	0.4
Number of full brothers	0.8	1.0	4.4	0.5	-0.1	-0.7	1.5	-1.0	0.1	2.1	0.5	-0.4
Worry too long after embarrassment	0.2	0.3	1.5	0.5	-0.5	0.0	0.3	0.6	0.2	0.0	1.2	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.9	0.0	0.1	-1.0	1.7	0.8	0.9	0.2	-0.7	-0.4
Wheeze or whistling in the chest in last year	0.8	1.4	2.7	-0.9	-1.7	-1.2	0.8	-0.0	1.6	1.3	-1.4	-1.0
Number of children fathered	0.2	0.2	0.5	-0.2	-0.4	0.3	0.3	0.7	0.6	-0.4	-0.0	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	3.1	1.3	1.5	0.5	-0.2	0.6	-0.1	-1.8	0.7	0.5
Age at first live birth	0.3	0.5	1.2	-1.1	-0.8	-0.2	0.9	0.6	0.0	-1.0	-0.3	-0.7
Pulse wave peak to peak time	1.3	1.6	8.2	0.4	0.9	0.4	-1.3	-2.9	-0.7	0.7	1.2	1.1
Health satisfaction	2.4	3.1	6.4	-0.5	-0.6	-2.5	2.1	1.3	2.3	0.5	-2.1	-2.3
Shortness of breath walking on level ground	1.5	1.8	4.6	-2.1	-1.7	-1.2	0.7	0.5	-0.3	1.7	-1.4	-1.4
Qualifications: College or University degree	1.3	4.2	8.9	-2.6	-0.8	-2.0	2.0	2.4	2.1	0.8	-3.0	-1.8
Eye problems/disorders: None of the above	0.3	0.4	2.1	-0.1	-0.2	-0.0	-0.6	-1.4	0.4	0.9	0.4	-0.4
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.4	-0.4	-0.6	-0.1	0.1	-0.1	0.3	0.2	0.1	0.2
Emphysema/chronic bronchitis	0.5	0.6	2.3	-0.2	-1.1	0.5	1.0	1.5	-0.4	0.4	0.0	0.1
Medication for pain relief, constipation, heartburn	0.5	0.9	2.1	0.2	0.9	1.2	-0.7	-0.8	-0.9	-1.0	1.0	1.4
Neck or shoulder pain in last month	0.1	0.1	0.5	0.7	-0.1	0.5	-0.1	-0.0	-0.2	-0.3	0.2	-0.2
Medication: Blood pressure	0.2	0.4	1.4	-0.0	-0.7	-0.6	0.3	-0.5	0.2	-0.8	-1.2	-0.6
Angina (self-reported)	0.7	0.9	3.8	-0.4	0.5	-0.8	-1.0	-1.9	1.1	0.6	-0.7	-0.9
Migraine (self-reported)	0.7	0.9	2.5	-0.2	0.0	-0.7	1.5	1.6	1.3	0.3	-0.3	-0.9
Medication: Ibuprofen	1.5	1.9	4.9	-1.1	-1.8	-0.7	2.2	1.1	0.4	1.9	-0.8	-1.1
Medication: Allopurinol	0.4	0.5	1.5	0.8	0.7	0.0	-0.7	-0.8	0.9	-1.2	0.2	-0.5
Medication: Omeprazole	0.5	0.6	2.8	-0.1	-1.4	0.5	0.4	-0.3	-1.7	-0.7	-0.1	0.3
Medication: Seretide 50 evohaler	0.9	1.0	2.5	-0.2	0.4	-0.6	-1.6	-1.6	1.3	0.9	-0.5	-0.9
Mean time to correctly identify matches	0.1	0.2	0.8	0.3	0.3	-0.1	0.9	-0.8	-0.3	0.5	0.0	-0.2
Heart disease (mother)	0.5	0.6	1.8	-0.7	-1.4	-0.2	-0.6	0.1	0.8	0.6	-0.9	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.0	0.6	-0.9	0.0	-0.0	-0.7	-0.1	1.0	0.8	-0.3
Whole body fat mass	0.3	1.1	5.1	-1.4	-2.3	-0.6	-0.0	-0.1	0.1	0.2	-1.2	-0.9
Leg fat mass (right)	0.6	2.2	7.3	-1.8	-2.7	-1.3	0.3	0.5	0.8	0.8	-1.8	-1.7
Arm predicted mass (right)	0.2	0.9	3.1	0.2	-0.6	1.3	-0.0	1.1	-1.8	-0.7	1.0	0.8
Pulse rate, automated reading	1.8	5.7	9.8	-3.1	-2.6	-2.2	1.3	2.0	2.2	1.6	-3.1	-2.8
Alcohol intake frequency.	0.7	1.5	4.5	-0.7	-1.5	-1.4	0.5	0.2	1.2	1.5	-0.8	-2.1
Comparative height size at age 10	0.4	2.4	4.0	1.3	0.9	1.8	-0.8	-0.7	-2.0	-2.0	2.0	1.7
Number of full sisters	3.2	3.9	11.3	-0.8	-0.7	-2.5	1.4	-1.0	3.4	2.9	-0.8	-2.2
Suffer from ‘nerves’	0.6	0.9	2.9	1.1	1.7	0.6	1.0	0.4	0.2	-1.5	0.8	0.1
Overall health rating	3.6	7.7	13.7	-2.4	-1.6	-3.6	2.9	1.1	2.8	2.2	-3.7	-3.5
Chest pain or discomfort	1.0	1.4	3.0	-1.7	-1.5	-1.0	-0.7	-0.5	0.7	0.9	-1.4	-1.4
Had major operations	0.8	0.9	2.2	1.0	0.0	0.9	-0.5	-1.5	-1.0	0.1	1.1	1.3
Age at last live birth	2.0	2.8	6.5	-1.8	-1.3	-1.3	2.2	0.8	2.6	0.9	-1.0	-2.2
Family relationship satisfaction	0.3	0.4	1.4	-0.8	-0.3	0.2	0.3	1.2	-0.0	-0.9	-0.6	-0.3
Leg pain on walking	0.2	0.3	0.7	-0.7	-0.7	-0.0	0.0	-0.9	-0.1	0.6	-0.6	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.7	-0.3	-0.6	-0.5	0.2	0.2	0.2	0.4	-0.8	-0.4
Commuting to job workplace: Car/motor vehicle	0.5	0.5	1.0	-0.7	-0.8	-0.6	-1.0	-0.5	0.9	0.8	-0.7	-0.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.3	0.2	0.0	-0.8	1.0	-0.1	0.8	-1.1	-0.6	-0.4
Medication: Aspirin	0.5	0.7	2.9	-0.4	0.4	-0.8	-0.4	-0.6	1.7	-0.2	-0.9	-0.9
Supplements: Vitamin C	0.7	0.9	2.7	-1.1	-0.9	0.4	0.9	1.6	-0.9	0.1	0.4	1.0
Knee pain experienced in last month	0.4	0.6	3.0	-0.1	-0.8	-0.4	0.0	-1.7	0.4	1.1	0.7	0.2
Hypertension (Self-reported)	1.1	3.1	6.0	-1.4	-2.0	-2.3	1.4	0.4	1.8	1.5	-1.8	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	5.9	-1.7	-2.4	-1.3	0.7	-0.9	0.8	1.6	-1.6	-0.8
Illnesses of father: Heart disease	1.6	2.3	9.7	-0.9	-0.9	-1.5	-0.2	-0.2	3.1	1.0	-1.4	-2.0
Illnesses of siblings: Diabetes	0.2	0.3	0.9	-0.1	-0.9	0.4	-0.5	-0.2	-0.9	-0.3	0.1	0.6
Smoking status: Previous	0.1	0.2	0.7	0.8	0.8	-0.2	0.1	-0.1	0.4	-0.2	-0.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.6	0.9	0.0	1.7	0.7	0.3	-1.9	-1.5	1.1	0.9
Whole body fat-free mass	0.2	1.2	4.8	-0.1	-0.8	1.3	0.2	1.0	-2.2	-0.6	1.0	0.9
Leg fat-free mass (right)	0.2	1.0	3.3	-1.1	-1.8	0.6	0.7	0.7	-1.6	-0.0	0.1	0.4
Arm fat percentage (left)	0.8	3.4	8.5	-2.2	-2.9	-1.8	0.5	-0.2	1.3	1.1	-2.4	-2.1
Average weekly red wine intake	0.2	0.2	1.0	0.1	0.2	0.6	0.1	0.4	-0.3	-1.0	0.0	0.7
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.9	0.9	0.6	0.2	-0.6	-0.3	-0.5	-0.3	0.4	1.0
Mood swings	0.5	0.9	4.1	1.3	1.2	-0.1	0.5	-0.2	0.5	-2.0	0.1	0.0
Loneliness, isolation	0.7	0.9	3.0	-0.8	0.1	-1.1	1.7	-0.7	0.9	1.3	-0.6	-0.8
Long-standing illness, disability or infirmity	0.4	0.7	1.6	-0.6	-1.2	-1.3	-0.3	-0.8	-0.6	0.7	-0.7	-0.8
Ever had bowel cancer screening	0.6	0.7	2.0	-1.4	-0.9	-0.5	0.8	-0.6	0.7	1.0	-0.7	-0.9
Diabetes diagnosed by doctor	0.3	0.5	1.3	-0.2	0.1	-1.1	-0.3	0.9	0.8	-0.2	-0.9	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.8	-0.4	0.1	-0.7	-0.3	-0.2	0.9	0.5	-0.9	-0.5
Friendships satisfaction	1.2	1.4	3.3	-0.7	-0.1	-1.5	1.2	1.4	1.8	0.6	-1.5	-1.0
Qualifications: nursing, teaching	1.1	1.6	5.0	0.4	1.6	1.7	-2.2	0.9	-0.3	-1.0	0.5	1.4
Commuting to job workplace: Walk	1.3	1.4	5.0	0.9	0.9	1.1	-1.1	2.2	-0.3	-1.8	0.5	0.3
Eye problems/disorders: Cataract	1.2	1.4	6.0	0.9	1.6	0.7	0.8	1.1	-0.6	-2.4	-0.1	0.6
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.6	0.5	0.0	0.4	-0.1	0.1	-0.6	-0.5	0.8	0.5
Medication for cholesterol	1.1	1.7	4.0	1.3	1.9	1.2	-1.0	-0.2	-0.7	-0.9	2.0	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	4.8	0.0	0.5	-0.9	2.2	0.1	1.0	-0.1	-1.4	-1.2
Back pain experienced in last month	0.5	0.8	2.7	-0.4	-0.5	-0.3	-1.6	1.6	-0.7	0.8	-0.2	-0.1
Mineral and other dietary supplements	0.8	1.0	2.3	-1.2	-1.2	-0.7	0.1	-0.8	0.8	1.5	-1.0	-1.2
Breast cancer (self-reported)	1.4	1.6	7.3	1.0	0.9	1.3	-0.6	-0.4	-2.7	-1.3	0.8	1.0
Asthma (self-reported)	0.2	0.4	1.8	0.5	1.0	-0.3	0.5	-0.3	1.3	-0.1	-0.2	-0.7
Osteoporosis (self-reported)	1.0	1.2	3.1	1.3	1.8	0.9	-0.2	0.6	-1.2	-1.2	0.9	1.0
Osteoarthritis (self-reported)	0.1	0.1	0.2	-0.2	0.0	-0.4	-0.5	0.5	-0.1	0.5	0.0	0.3
Medication: Aspirin	0.7	1.0	4.1	-0.8	0.0	-1.1	0.2	-0.5	2.0	0.3	-1.1	-1.1
Medication: Gliclazide	0.5	0.6	2.0	-0.6	-1.4	-0.1	0.4	0.9	-0.9	1.1	0.3	0.2
Illnesses of father: None of the above (group 1)	1.3	1.5	7.3	0.2	0.9	1.2	-0.2	0.3	-2.7	-0.7	0.8	1.8
Smoking status: Current	0.2	0.3	1.7	0.6	-0.2	-0.4	0.4	0.2	0.2	-0.2	-1.3	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.0	-0.0	0.4	0.0	-0.9	-0.4	-0.1	-1.0	-0.6	-0.0
Whole body water mass	0.2	1.2	4.8	-0.2	-0.9	1.4	0.3	1.1	-2.2	-0.6	1.0	0.9
Leg predicted mass (right)	0.2	1.0	3.1	-1.0	-1.8	0.7	0.6	0.7	-1.7	-0.1	0.2	0.5
Arm fat mass (left)	0.4	1.5	5.8	-1.5	-2.4	-0.9	0.3	0.0	0.5	0.6	-1.5	-1.3
Number of self-reported non-cancer illnesses	3.4	5.8	8.6	-2.0	-2.0	-2.9	2.2	-0.0	2.9	2.8	-2.5	-2.8
Average weekly champagne plus white wine intake	0.2	0.2	1.2	0.4	-0.3	-0.1	-0.7	-1.1	-0.2	-0.1	-0.4	-0.0
Miserableness	0.3	0.5	0.8	0.8	-0.6	-0.8	0.8	-0.5	0.8	0.0	-0.2	-0.9
Guilty feelings	0.3	0.4	1.9	0.1	0.8	0.1	-0.1	1.4	0.5	-0.0	0.7	-0.4
Wears glasses or contact lenses	0.5	0.6	1.8	0.1	-0.6	1.0	1.3	0.6	-0.8	-0.9	0.7	-0.1
Ever taken oral contraceptive pill	0.7	0.8	3.5	-1.2	-1.9	-0.5	-0.3	0.7	0.0	0.5	-1.0	-0.5
Hearing aid user	0.4	0.4	1.2	1.1	0.6	0.7	-0.6	-0.5	-0.5	-0.5	0.5	0.3
Mother’s age at death	0.6	0.7	2.4	1.0	0.8	0.7	-0.8	-0.7	0.8	0.4	1.5	0.3
Financial situation satisfaction	0.3	0.4	1.6	0.3	0.8	0.4	1.3	0.8	-0.5	0.4	0.3	-0.1
Tinnitus: Yes, now most or all of the time	1.8	2.1	5.2	0.9	1.7	1.8	-2.0	0.0	-0.7	-2.3	0.7	1.4
Commuting to job workplace: Public transport	0.5	0.6	1.3	1.1	0.7	0.5	0.8	-0.6	-1.1	-1.1	0.3	-0.0
Eye problems/disorders: Glaucoma	0.8	1.0	3.4	-0.5	-1.5	0.3	-0.4	1.2	-1.8	-0.1	0.8	0.7
Medication: Blood pressure	0.5	0.9	1.6	-0.8	-0.9	-1.1	0.5	-0.8	0.9	0.9	-1.3	-1.3
Pain type(s) experienced in last month: Hip pain	1.2	1.5	5.4	-0.6	-2.3	-1.6	0.3	1.6	0.3	1.0	-0.4	-1.2
Supplements: Fish oil (including cod liver oil)	1.0	1.4	3.4	1.8	0.7	0.9	0.5	0.8	-1.5	-1.1	1.6	1.0
High cholesterol (Self-reported)	0.3	0.5	1.1	-0.6	-0.6	-0.6	0.4	-0.8	0.4	0.9	-1.1	-0.3
Medication: Bendroflumethiazide	0.6	0.9	2.9	-1.0	-1.4	-0.6	0.3	0.0	1.0	1.7	-0.4	-0.9
Medication: Paracetamol	0.9	1.3	3.1	0.1	-0.8	-1.4	1.8	1.3	0.8	1.7	-0.3	-1.0
Medication: Lisinopril	0.6	0.8	2.2	-0.0	-0.1	-1.1	-0.1	-0.6	1.5	1.4	-0.2	-1.3
Medication: Atorvastatin	0.5	0.6	1.7	-0.1	0.0	-1.3	0.5	-0.3	0.8	0.7	-1.1	-0.8
Illnesses of father: High blood pressure	0.7	0.9	2.4	1.6	1.3	0.8	-1.1	0.0	0.2	-0.8	1.3	0.4
Alcohol drinker status: Never	1.1	1.3	2.5	-1.4	-1.6	-1.2	0.8	1.4	-0.1	1.4	-0.9	-1.0
Ever smoked	0.5	0.8	2.6	0.2	-0.2	-1.4	0.8	0.1	0.9	0.4	-1.6	-1.0
Basal metabolic rate	0.2	1.0	3.7	-0.4	-1.2	1.0	0.3	1.0	-1.9	-0.5	0.6	0.6
Leg fat percentage (left)	1.4	5.0	11.4	-2.6	-3.4	-2.5	0.2	0.0	1.6	1.9	-2.9	-2.3
Arm fat-free mass (left)	0.2	1.0	3.0	-0.4	-1.0	1.1	0.1	1.6	-1.7	-0.2	0.7	0.9
Number of operations (self-reported)	0.3	0.5	1.4	1.2	-0.2	-0.0	1.2	-1.0	0.5	0.2	0.2	0.0
Average weekly beer plus cider intake	1.4	2.0	3.7	-0.9	-1.9	-1.8	-0.3	-0.9	0.2	1.9	-1.9	-1.5
Irritability	0.2	0.4	1.0	0.7	-0.3	0.5	-1.0	1.0	0.2	-0.5	0.6	0.3
Risk taking	1.4	2.0	4.3	-1.1	-1.0	-1.7	-1.2	-1.7	1.0	1.3	-2.1	-1.4
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.8	-0.3	-1.0	0.0	1.4	1.0	0.3	-0.7	-0.2	-0.7
Fractured/broken bones in last 5 years	0.9	1.2	2.9	0.7	1.0	1.2	-0.2	0.6	-1.7	-1.5	0.7	1.4
Age started oral contraceptive pill	0.4	0.5	2.1	0.0	0.4	-0.8	-0.5	0.4	1.4	0.4	-0.4	-0.9
Diastolic blood pressure, automated reading	0.1	0.3	1.5	-0.6	-0.3	-0.1	-0.0	0.9	-0.3	-0.3	-1.2	-0.4
Ever depressed for a whole week	0.8	1.0	4.0	0.1	0.7	-0.6	2.0	1.0	0.9	1.6	0.1	-0.5
Unable to work because of sickness or disability	1.8	2.3	5.9	-1.7	0.1	-1.5	1.5	0.6	2.4	1.8	-1.3	-1.4
Commuting to job workplace: Cycle	0.4	0.4	1.4	0.3	0.8	0.5	0.6	-1.2	-0.7	-0.2	0.8	0.3
Myopia	1.6	2.3	10.6	-1.7	-3.3	-1.0	1.2	0.6	0.1	1.4	-0.6	-1.4
Vascular/heart problems diagnosed by doctor	1.1	3.0	5.6	1.2	1.9	2.4	-1.0	0.5	-1.9	-1.5	1.9	2.3
Cholesterol lowering medication	0.4	0.6	2.0	-1.1	-0.2	-0.3	-0.2	-0.5	0.6	1.0	-1.4	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.9	-0.1	-1.4	0.4	0.2	0.1	-1.2	-0.2	-0.1	0.2
Pain experienced in last month	0.2	0.3	0.9	0.2	0.4	0.8	-0.6	-0.5	-0.2	-0.3	1.0	0.7
Supplements: Calcium	1.7	1.9	4.0	1.7	2.0	0.9	0.4	2.0	-0.6	-1.2	1.6	1.0
Basal cell carcinoma (self-reported)	1.5	1.7	3.5	-0.9	-0.7	-1.5	1.9	0.3	1.5	0.1	-1.9	-1.7
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.9	-0.5	-1.2	-1.3	0.2	-2.0	0.6	1.0	-0.9	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	4.3	-0.1	-0.0	-0.9	0.5	0.1	2.1	-0.1	-0.8	-0.4
Heart disease (siblings)	0.3	0.4	2.0	0.4	0.1	0.8	-0.7	-1.4	-0.4	0.1	0.5	0.1
Alcohol drinker status: Previous	0.2	0.3	1.9	0.3	0.3	0.2	1.4	-0.3	0.1	0.4	0.3	-0.2
Pack years of smoking	0.7	1.1	3.4	0.9	0.9	-0.9	1.9	-0.9	1.1	0.3	-0.6	-1.1
Impedance of whole body	1.1	5.5	8.5	2.5	2.8	2.7	-1.9	-1.2	-1.5	-2.9	2.2	2.7
Leg fat mass (left)	0.6	2.3	7.7	-1.9	-2.8	-1.4	0.4	0.3	0.8	0.8	-1.9	-1.6
Arm predicted mass (left)	0.2	1.1	3.7	0.1	-0.7	1.2	0.2	1.5	-1.9	-0.4	0.9	0.9