TWAS hub - COG6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1450	0.0350	9.0e-07	0.056	0.057	0.074	0.070	0.061	2.1e-07	1.7e-07	2.6e-09	6.9e-09	6.0e-08
2	GTEx	Adipose Subcutaneous	0.2050	0.0470	5.9e-08	0.163	NA	0.123	NA	0.136	2.6e-13	NA	3.1e-10	NA	3.1e-11
3	GTEx	Adipose Visceral Omentum	0.1250	0.0510	8.4e-03	0.118	NA	0.130	NA	0.127	1.1e-06	NA	2.9e-07	NA	4.2e-07
4	GTEx	Artery Aorta	0.3120	0.0570	2.1e-09	0.230	NA	0.280	NA	0.257	6.9e-13	NA	9.3e-16	NA	2.0e-14
5	GTEx	Artery Tibial	0.1549	0.0420	2.0e-06	0.107	NA	0.095	NA	0.122	1.0e-08	NA	6.4e-08	NA	8.1e-10
6	GTEx	Brain Hippocampus	0.2877	0.1074	7.3e-03	0.176	NA	0.064	NA	0.111	6.5e-05	NA	1.3e-02	NA	1.5e-03
7	GTEx	Cells Transformed fibroblasts	0.4420	0.0530	0.0e+00	0.413	NA	0.367	NA	0.397	3.2e-33	NA	8.8e-29	NA	1.2e-31
8	GTEx	Esophagus Muscularis	0.2140	0.0560	5.9e-06	0.193	NA	0.171	NA	0.187	7.5e-12	NA	1.4e-10	NA	1.6e-11
9	GTEx	Heart Atrial Appendage	0.1510	0.0580	5.6e-03	0.065	NA	0.014	NA	0.025	7.2e-04	NA	7.4e-02	NA	2.7e-02
10	GTEx	Heart Left Ventricle	0.2240	0.0536	9.1e-07	0.163	NA	0.124	NA	0.146	5.2e-09	NA	3.9e-07	NA	3.4e-08
11	GTEx	Lung	0.1003	0.0373	2.3e-03	0.043	NA	0.059	NA	0.055	3.1e-04	NA	2.5e-05	NA	4.9e-05
12	GTEx	Muscle Skeletal	0.4083	0.0424	0.0e+00	0.398	NA	0.451	NA	0.448	1.2e-41	NA	8.6e-49	NA	2.6e-48
13	GTEx	Nerve Tibial	0.1994	0.0502	5.4e-06	0.181	NA	0.169	NA	0.179	7.8e-13	NA	5.2e-12	NA	1.0e-12
14	GTEx	Testis	0.4260	0.0700	1.8e-12	0.372	NA	0.370	NA	0.368	1.8e-17	NA	2.2e-17	NA	3.0e-17
15	GTEx	Whole Blood	0.1010	0.0350	1.0e-03	0.071	NA	0.036	NA	0.081	4.5e-07	NA	2.8e-04	NA	7.0e-08
16	METSIM	Adipose	0.0684	0.0204	2.1e-05	0.062	0.039	0.064	0.049	0.060	1.3e-09	1.3e-06	8.1e-10	6.0e-08	2.2e-09
17	YFS	Blood	0.0692	0.0140	5.6e-17	0.076	0.056	0.072	0.073	0.075	9.0e-24	1.2e-17	1.5e-22	9.8e-23	1.6e-23
18	TCGA	Cervical Squamous Cell Carcinoma	0.1720	0.0950	3.5e-04	0.088	0.066	0.092	NA	0.067	4.0e-05	3.6e-04	2.7e-05	NA	3.3e-04
19	TCGA	Glioblastoma Multiforme	0.2420	0.0930	4.3e-05	0.204	0.113	0.131	NA	0.163	8.1e-07	2.7e-04	8.6e-05	NA	1.2e-05
20	TCGA	Head and Neck Squamous Cell Carcinoma	0.0429	0.0236	3.2e-03	0.030	0.023	0.017	NA	0.022	2.3e-04	1.1e-03	4.6e-03	NA	1.4e-03
21	TCGA	Kidney Renal Clear Cell Carcinoma	0.0419	0.0188	2.8e-04	0.033	0.031	0.025	NA	0.027	1.1e-04	1.9e-04	6.4e-04	NA	4.5e-04
22	TCGA	Brain Lower Grade Glioma	0.1343	0.0395	0.0e+00	0.146	0.175	0.181	NA	0.186	2.9e-16	1.9e-19	4.6e-20	NA	1.1e-20
23	TCGA	Lung Adenocarcinoma	0.0292	0.0155	1.5e-03	0.003	0.010	0.007	NA	-0.001	1.2e-01	2.4e-02	5.0e-02	NA	4.4e-01
24	TCGA	Lung Squamous Cell Carcinoma	0.0318	0.0182	4.8e-03	0.022	0.007	0.000	NA	0.008	1.3e-03	4.8e-02	3.6e-01	NA	4.0e-02
25	TCGA	Stomach Adenocarcinoma	0.0540	0.0320	6.7e-03	0.004	0.023	0.016	NA	0.013	1.6e-01	8.2e-03	2.2e-02	NA	3.7e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Fractured/broken bones in last 5 years	8.8	11.4	20.8	1.5	-3.3	-2.7	-2.7	-2.7	-3.2	-3.4	-3.3	-3.0	-3.0	-4.5	-2.9	-3.4	-0.6	-4.2	-4.3	-3.8	-3.1	-3.1	-4.6	-4.5	-2.1	-2.9	-4.1	-4.1
Rheumatoid Arthritis	8.1	11.1	19.7	-2.9	3.7	3.7	3.1	4.0	3.5	3.8	3.8	3.3	4.3	4.4	4.1	3.8	3.6	3.9	3.6	1.1	0.5	3.4	2.4	3.3	4.0	-0.4	2.0	1.9
Number of full sisters	7.8	9.5	14.7	0.9	-3.2	-3.4	-2.5	-3.7	-3.7	-3.5	-3.8	-3.5	-3.6	-3.5	-3.5	-3.6	-2.7	-3.7	-3.1	-1.7	-1.1	-3.6	-3.2	-3.1	-3.6	-0.6	-2.1	-2.5
Blood Eosinophil Count	6.8	52.0	86.9	-5.2	8.2	7.4	7.0	8.6	7.8	8.0	8.2	7.9	9.3	7.9	8.6	8.0	8.2	8.5	8.7	2.9	1.3	7.8	4.4	7.9	8.5	-0.7	5.0	4.8
Age when periods started (menarche)	6.3	15.2	27.4	0.5	-4.7	-3.9	-2.9	-5.1	-4.1	-4.6	-4.7	-4.5	-5.0	-5.2	-5.1	-4.6	-5.2	-4.3	-4.6	0.0	0.6	-4.1	-1.3	-2.7	-5.2	1.1	-1.0	-2.1
Depression (self-reported)	5.6	6.7	12.9	-0.7	3.0	3.5	2.2	3.1	3.3	2.9	3.2	3.0	2.9	3.6	3.2	3.0	2.5	2.7	3.2	0.6	0.2	3.2	1.6	1.8	2.9	-0.6	1.2	1.3
Happiness	5.0	6.0	10.0	-1.6	2.6	3.1	2.6	2.7	2.6	2.5	3.0	2.9	2.8	3.0	2.6	2.6	1.2	2.7	3.2	1.4	1.0	2.5	2.1	2.7	2.5	0.6	2.0	2.4
Neuroticism (2016)	4.4	6.3	11.0	-1.2	2.8	2.7	2.9	2.4	3.3	2.8	2.8	2.9	2.6	2.6	2.6	2.8	0.8	3.0	3.1	2.1	0.9	3.3	2.4	2.7	1.9	1.1	2.3	2.5
Commuting to job workplace: Walk	4.2	4.5	8.6	-0.5	2.6	1.9	2.4	2.4	2.5	2.6	2.7	2.8	2.9	2.2	2.6	2.6	1.5	2.6	2.2	0.5	-0.5	2.4	1.4	2.3	2.3	0.4	0.8	1.3
Mean Putamen Volume	4.1	4.6	8.6	1.2	2.6	2.4	2.7	2.8	2.6	2.5	2.6	2.6	2.6	2.0	2.6	2.5	2.7	2.1	2.2	-0.2	-0.3	2.7	0.7	0.7	2.9	-1.1	0.2	0.7
Respiratory disease	3.4	7.5	15.6	-1.8	3.1	2.8	3.0	3.5	3.0	3.0	3.3	3.2	3.7	2.5	3.4	3.1	3.9	2.9	2.8	0.1	0.1	3.0	1.0	2.4	3.6	-1.2	1.0	1.3
Family relationship satisfaction	3.4	4.1	7.7	-0.1	2.4	2.7	2.4	2.4	2.7	2.3	2.5	2.4	2.2	2.1	2.4	2.4	1.9	2.1	2.4	0.2	-0.1	2.8	1.4	1.4	2.3	0.0	0.6	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.4	4.0	8.3	0.6	2.4	2.3	2.4	2.8	2.4	2.3	2.3	2.5	2.5	1.2	2.9	2.4	2.6	2.0	1.8	-0.3	-0.1	2.4	0.4	0.6	2.9	-1.3	0.2	0.7
Asthma	3.2	6.3	12.4	-1.6	2.9	2.6	2.3	3.2	2.8	2.8	3.0	2.9	3.2	3.0	3.2	2.9	3.5	2.7	2.6	0.1	-0.1	2.9	0.9	1.9	3.3	-1.2	0.9	1.0
Medication: Aspirin	3.2	4.3	6.9	-0.3	-2.2	-1.6	-2.2	-1.7	-2.2	-2.4	-2.4	-2.5	-1.9	-2.4	-1.9	-2.4	0.2	-2.6	-2.6	-2.0	-1.7	-2.1	-2.1	-2.3	-1.2	-1.8	-2.1	-2.5
Neuroticism score	3.0	6.2	11.1	-0.1	2.9	3.3	3.1	3.0	3.0	2.9	3.1	3.3	2.9	3.0	3.1	3.0	1.7	2.6	2.7	0.8	-0.3	2.9	1.5	1.8	2.8	-0.1	1.2	1.5
Asthma (self-reported)	2.9	5.7	11.1	-1.2	2.8	2.5	2.3	3.0	2.8	2.7	2.8	2.8	3.1	2.7	3.0	2.7	3.3	2.6	2.5	0.2	0.0	2.8	0.9	1.8	3.1	-1.1	0.9	1.0
Ever highly irritable/argumentative for 2 days	2.8	3.3	6.9	-0.9	1.9	2.2	2.4	2.2	2.6	1.9	2.3	2.2	1.8	1.7	2.1	2.1	1.6	1.9	1.7	0.5	0.1	2.6	1.5	1.2	2.0	0.3	0.9	1.6
Medication: Omeprazole (e.g. Zanprol)	2.8	3.4	6.9	1.3	2.3	2.0	2.3	2.4	2.2	2.3	2.5	2.6	2.2	1.7	2.3	2.3	0.9	1.8	1.8	-0.7	-0.9	2.2	0.1	1.0	2.3	-1.1	-0.6	-0.1
Ulcerative Colitis	2.7	4.0	9.0	-1.0	1.8	2.0	1.3	1.7	2.2	1.8	2.1	1.8	1.8	2.1	1.8	2.0	0.6	2.4	2.2	2.1	1.7	2.1	2.3	2.8	1.3	1.7	2.5	3.0
Forced expiratory volume in 1-second (FEV1), Best measure	2.7	8.7	14.8	0.5	-3.5	-3.0	-3.0	-3.7	-3.7	-3.4	-3.5	-3.1	-3.8	-3.9	-3.6	-3.4	-3.7	-3.3	-3.2	-0.4	-0.2	-3.7	-1.9	-2.2	-3.6	0.7	-0.9	-1.4
Exposure to tobacco smoke at home	2.7	3.0	6.1	-0.8	-2.0	-1.9	-2.2	-2.1	-2.1	-2.0	-2.1	-2.5	-2.2	-2.4	-2.0	-2.1	-1.6	-1.7	-1.6	0.3	0.5	-2.1	-0.2	-1.1	-2.1	0.7	0.2	-0.5
Triglycerides	2.6	4.2	9.1	0.1	2.1	2.0	2.1	1.7	2.7	2.2	2.3	1.9	1.9	1.6	1.9	2.3	0.0	2.5	2.5	2.0	1.4	2.6	3.0	2.3	1.3	1.6	2.1	2.2
Lung FEV1/FVC ratio	2.6	13.3	27.5	0.3	-4.2	-3.6	-4.0	-4.2	-4.1	-4.4	-4.5	-4.3	-4.5	-3.1	-4.3	-4.5	-2.5	-4.5	-5.2	-1.7	-0.8	-4.0	-3.4	-4.1	-3.9	-0.2	-2.2	-1.7
Sensitivity / hurt feelings	2.6	4.5	7.7	-0.9	2.5	2.8	2.8	2.2	2.3	2.5	2.7	2.8	2.1	2.7	2.5	2.5	1.1	2.4	2.6	1.1	-0.0	2.1	1.3	2.4	1.8	0.3	1.4	1.3
Worrier / anxious feelings	2.6	4.9	9.2	0.7	2.6	3.0	2.7	2.8	2.8	2.5	2.7	2.7	2.5	3.0	2.9	2.6	2.1	2.1	2.1	-0.2	-1.2	2.8	0.4	0.9	2.7	-1.2	0.3	0.5
Serious illness, injury or assault of a close relative in last 2 years	2.6	3.0	5.2	-0.4	2.2	1.9	1.9	2.3	2.1	2.1	2.1	2.1	2.2	1.7	2.2	2.1	1.6	2.0	1.8	0.3	0.2	2.2	0.6	1.3	2.2	-0.4	0.7	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	4.0	10.9	0.0	2.5	2.8	1.9	2.4	2.4	2.3	2.5	2.4	2.0	3.3	2.4	2.4	1.4	2.1	2.3	0.4	-0.2	2.4	1.1	1.5	2.2	-0.5	0.8	0.7
Exposure to tobacco smoke outside home	2.6	3.5	7.8	-0.9	-2.4	-2.1	-2.8	-2.2	-2.1	-2.2	-2.3	-2.8	-2.4	-2.2	-2.0	-2.2	-1.3	-1.9	-1.8	0.1	0.9	-2.1	-0.1	-1.5	-2.0	-0.0	-0.0	-1.2
Wheeze or whistling in the chest in last year	2.6	4.6	8.8	1.6	2.6	2.1	2.4	2.7	2.9	2.4	2.8	2.9	2.6	2.8	2.8	2.5	1.9	2.0	2.0	-0.2	-0.4	3.0	0.6	0.9	2.6	-1.2	0.0	0.4
Suffer from ‘nerves’	2.6	4.1	9.7	1.0	2.3	1.9	2.5	2.4	2.4	2.3	2.5	2.7	2.3	3.1	2.4	2.4	1.1	2.3	1.9	0.4	-0.6	2.3	1.6	1.5	2.3	0.6	0.8	1.6
Medication: Aspirin	2.6	3.4	5.7	-0.4	-2.1	-1.4	-1.9	-1.7	-2.1	-2.3	-2.2	-2.2	-2.0	-2.1	-1.9	-2.2	-0.4	-2.4	-2.4	-1.4	-1.3	-2.0	-1.7	-1.8	-1.4	-1.2	-1.6	-1.9
Medication: Ventolin 100micrograms inhaler	2.5	3.2	6.4	-1.0	2.3	2.3	1.2	2.2	1.8	2.2	2.1	1.9	2.5	2.2	2.4	2.1	2.1	2.1	1.9	0.2	-0.1	1.8	0.9	1.2	2.3	-0.9	0.7	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	2.5	3.3	10.4	2.0	1.9	2.4	1.5	2.0	2.4	1.9	2.5	2.5	1.6	3.2	2.1	2.1	0.6	1.5	2.0	-0.1	-1.1	2.4	1.0	1.1	1.7	-0.0	0.1	0.6
Frequency of depressed mood in last 2 weeks	2.4	3.4	7.4	-0.9	1.7	2.7	1.6	2.0	2.4	1.8	2.5	2.3	2.1	2.0	2.1	2.0	1.2	1.8	1.6	1.0	0.7	2.4	1.9	1.9	1.8	0.4	1.4	1.7
Height	2.3	44.6	70.1	4.1	-7.0	-5.4	-6.6	-6.5	-7.2	-7.1	-6.9	-6.2	-6.8	-7.1	-6.9	-7.1	-3.0	-8.4	-8.1	-6.1	-5.9	-7.2	-8.1	-7.3	-6.0	-3.9	-7.0	-8.1
Hearing difficulty/problems: Yes	2.3	3.4	7.7	-0.0	2.1	2.5	1.9	2.1	2.7	2.1	2.2	2.0	2.2	2.3	2.0	2.2	1.3	2.1	1.5	0.7	0.7	2.8	1.8	1.2	2.1	0.1	0.9	1.4
Ever unenthusiastic/disinterested for a whole week	2.3	2.8	5.8	-0.8	1.9	1.8	1.9	2.0	2.1	1.8	2.3	2.4	1.8	2.1	1.9	1.9	1.1	1.7	1.9	0.4	-0.3	2.2	1.0	1.6	1.8	-0.2	0.6	1.1
Friendships satisfaction	2.3	2.9	6.5	1.1	1.7	1.9	2.2	2.3	2.0	1.7	2.1	2.0	2.2	1.5	2.1	1.8	2.4	1.3	1.7	-0.8	-0.7	2.0	0.2	0.2	2.6	-1.5	-0.4	0.1
Eye problems/disorders: Glaucoma	2.3	2.7	6.0	1.8	-1.5	-1.3	-1.4	-1.2	-1.3	-1.6	-1.5	-1.7	-1.7	-1.6	-1.5	-1.6	-0.6	-2.1	-1.9	-1.9	-1.3	-1.3	-1.6	-2.5	-1.0	-1.4	-2.2	-2.2
Relative age of first facial hair	2.2	4.5	9.4	-0.5	-2.4	-3.1	-2.4	-2.7	-2.7	-2.3	-2.6	-2.5	-2.4	-2.0	-2.6	-2.4	-2.8	-2.1	-2.0	0.4	1.0	-2.7	-1.0	-1.1	-2.8	0.5	-0.1	-1.0
Bilateral oophorectomy (both ovaries removed)	2.2	2.5	5.6	-1.5	1.2	1.4	1.4	0.8	1.5	1.3	1.4	1.6	1.1	0.8	0.9	1.4	-0.7	1.7	1.9	2.4	1.7	1.5	2.4	2.1	0.3	1.9	2.2	2.1
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.4	6.0	1.2	2.2	2.1	2.3	2.4	2.3	2.1	2.5	2.3	2.0	2.2	2.4	2.3	1.6	1.8	1.8	-0.1	-0.4	2.3	0.9	0.7	2.3	-0.2	0.2	1.1
Medication: Gliclazide	2.2	2.5	5.6	1.3	2.1	2.1	1.2	1.5	1.5	1.9	1.7	1.9	1.7	2.4	1.9	1.9	1.2	1.9	2.0	0.8	-0.2	1.5	1.5	1.6	1.4	0.0	1.0	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.7	8.3	0.0	-2.6	-2.2	-2.3	-2.9	-2.8	-2.7	-2.6	-2.2	-2.7	-2.5	-2.8	-2.6	-2.2	-2.3	-2.9	0.1	0.4	-2.8	-0.9	-1.2	-2.8	1.4	-0.2	-0.2
Medication: Co-codamol	2.1	2.4	5.4	0.8	1.8	1.6	1.6	1.7	2.3	1.8	2.0	1.9	1.5	1.0	1.7	1.9	0.0	1.8	1.6	0.7	0.6	2.3	1.8	1.2	1.3	0.8	0.7	1.7
Forced expiratory volume in 1-second (FEV1)	2.1	7.1	12.7	0.6	-3.0	-2.7	-2.3	-3.3	-3.3	-3.1	-3.1	-2.8	-3.3	-3.6	-3.2	-3.1	-3.4	-3.0	-3.0	-0.4	-0.1	-3.4	-1.8	-2.0	-3.3	0.5	-0.9	-1.4
Miserableness	2.1	3.6	7.6	-0.8	2.3	2.3	2.8	2.5	2.1	2.3	2.4	2.5	2.3	1.5	2.5	2.3	1.6	2.0	1.9	0.0	-0.7	2.1	0.9	1.2	2.4	-0.8	0.5	0.4
Depression (Nagel 2018)	2.0	3.1	5.7	-1.4	1.6	2.3	1.7	2.0	2.3	1.7	2.3	2.2	1.8	2.4	2.0	1.9	1.5	1.6	1.7	0.5	0.4	2.3	1.6	1.6	1.9	-0.3	0.9	1.1
Glaucoma (self-reported)	2.0	2.4	3.7	0.8	-1.7	-1.6	-1.8	-1.7	-1.4	-1.8	-1.8	-1.9	-1.9	-1.5	-1.9	-1.8	-1.5	-1.9	-1.8	-0.6	0.2	-1.4	-1.0	-1.8	-1.7	-0.6	-1.0	-1.4
Forced vital capacity (FVC), Best measure	2.0	7.2	13.9	0.3	-3.1	-2.7	-2.7	-3.4	-3.4	-3.0	-3.1	-2.7	-3.3	-3.7	-3.2	-3.0	-3.7	-2.9	-2.7	-0.1	-0.3	-3.5	-1.6	-1.6	-3.5	0.9	-0.6	-1.4
Medication: Omeprazole	2.0	2.3	4.3	1.4	2.0	1.7	2.1	1.9	1.6	2.0	2.0	2.0	1.6	1.2	2.0	2.0	0.7	1.5	1.7	-0.5	-0.7	1.6	0.2	0.7	1.8	-1.0	-0.5	-0.4
Overall health rating	2.0	4.4	8.0	-1.0	2.6	2.7	2.1	2.6	2.6	2.3	2.3	2.2	2.6	1.9	2.8	2.3	2.8	2.2	2.0	0.4	0.3	2.7	1.3	1.4	2.6	-0.8	1.0	0.9
Ever had prostate specific antigen (PSA) test	2.0	2.3	6.3	0.2	1.8	1.5	1.9	1.6	2.0	1.8	1.9	1.9	1.6	2.5	1.8	1.9	1.0	1.7	1.6	0.3	0.1	1.9	1.2	1.4	1.5	0.0	0.4	0.5
Forced vital capacity (FVC)	1.9	7.3	14.9	1.0	-3.1	-2.9	-2.4	-3.3	-3.4	-3.0	-3.1	-2.7	-3.2	-3.9	-3.2	-3.0	-3.1	-3.0	-2.9	-0.8	-0.6	-3.5	-2.2	-2.1	-3.3	0.2	-1.3	-1.8
Standing height	1.9	19.1	31.0	2.0	-4.7	-4.2	-4.6	-4.4	-4.9	-4.8	-4.5	-4.1	-4.7	-4.4	-4.4	-4.7	-2.2	-5.5	-5.0	-3.7	-3.4	-4.9	-5.1	-4.2	-4.1	-2.7	-4.3	-5.6
Tense / ‘highly strung’	1.9	3.2	8.8	-0.8	1.9	1.6	1.7	1.8	2.1	2.0	2.2	2.5	1.8	3.0	2.1	2.1	1.0	2.0	2.0	1.3	0.6	2.1	1.3	2.2	1.5	0.0	1.5	1.0
Mood swings	1.9	3.4	6.4	0.1	2.1	2.5	2.4	2.5	2.1	2.1	2.4	2.5	2.0	2.4	2.3	2.2	1.8	1.7	1.4	-0.1	-0.8	2.1	0.7	1.2	2.5	-0.9	0.2	0.3
Neuroticism (Nagel 2018)	1.8	4.1	10.1	0.1	2.2	2.7	2.5	2.6	2.6	2.2	2.6	2.7	2.1	3.2	2.5	2.4	1.9	1.8	1.8	-0.1	-0.9	2.6	0.8	1.0	2.4	-1.0	0.3	0.4
Hand grip strength (left)	1.8	4.6	10.1	1.8	-2.0	-1.4	-2.2	-1.8	-2.0	-2.0	-1.9	-1.9	-2.1	-1.9	-1.7	-2.0	-1.9	-2.6	-2.6	-2.4	-1.7	-1.9	-3.2	-2.8	-1.7	-1.8	-2.7	-2.8
Taking other prescription medications	1.8	2.8	5.3	-0.0	1.9	2.2	1.8	2.1	2.0	1.8	1.9	1.9	2.1	2.2	2.3	1.8	2.2	1.4	1.5	-0.6	-0.4	2.0	0.1	0.5	2.2	-1.6	-0.2	-0.2
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	6.1	-1.4	1.3	0.2	1.4	0.4	0.5	1.0	0.9	0.9	0.4	0.8	0.7	1.0	-0.7	1.6	1.2	2.2	1.6	0.4	1.9	2.5	-0.0	2.3	2.3	2.0
Medication: Blood pressure	1.8	3.1	6.1	-0.2	-2.3	-1.2	-2.1	-2.2	-2.0	-2.4	-2.2	-2.1	-2.1	-2.5	-2.0	-2.3	-1.2	-2.3	-2.1	-0.2	0.0	-2.0	-1.1	-1.5	-2.1	0.3	-0.4	-0.5
Heart disease (mother)	1.8	2.2	5.9	-0.5	1.2	1.5	0.8	0.9	1.6	1.2	1.2	1.1	1.1	1.7	1.2	1.3	-0.2	1.7	1.3	2.1	1.8	1.6	2.4	1.6	0.6	1.6	2.1	2.3
Worry (Nagel 2018)	1.7	3.6	11.3	0.1	2.0	1.9	2.0	2.0	2.5	2.1	2.4	2.6	2.0	3.4	2.1	2.2	0.9	2.0	1.7	0.9	0.1	2.5	1.6	1.7	1.7	0.5	1.2	1.4
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.8	6.8	-0.7	2.1	2.6	2.0	2.2	1.8	1.9	2.0	1.9	1.7	1.8	2.3	2.0	1.9	1.5	1.3	-0.8	-1.1	1.7	0.4	0.7	2.3	-0.9	-0.4	0.0
Birth weight of first child	1.7	3.2	9.1	1.1	-1.7	-1.5	-1.7	-1.4	-1.8	-1.6	-1.8	-1.3	-1.5	-1.8	-1.2	-1.6	-0.9	-2.1	-1.8	-2.0	-1.7	-1.8	-2.4	-2.0	-1.1	-1.8	-2.5	-3.0
Eye problems/disorders: Cataract	1.7	2.0	6.6	1.1	1.7	1.5	1.5	1.5	1.8	1.7	1.8	1.7	1.4	2.6	1.7	1.7	-0.1	1.5	1.5	0.2	-0.2	1.8	1.4	0.7	1.3	0.5	0.0	0.7
Medication for cholesterol	1.7	2.5	4.5	0.7	-1.9	-1.2	-1.7	-1.4	-1.6	-1.8	-1.6	-1.7	-1.5	-1.6	-1.6	-1.7	-0.0	-2.1	-2.0	-1.7	-1.0	-1.6	-2.1	-2.0	-1.1	-1.2	-1.6	-1.6
Unable to work because of sickness or disability	1.7	2.2	4.3	-1.2	1.4	1.7	1.6	1.8	2.0	1.4	1.9	1.8	1.6	0.3	1.6	1.5	2.0	1.4	1.2	0.6	0.5	2.1	0.9	1.2	1.8	0.1	1.1	1.8
Major Depression (MDD)	1.6	1.9	4.5	-1.4	1.5	1.4	1.0	1.7	1.6	1.5	1.5	1.2	1.6	1.0	1.6	1.5	1.2	1.6	2.1	0.6	0.9	1.7	1.3	1.4	1.8	-0.7	1.1	0.4
Body Mass Index (BMI) (2010)	1.6	2.2	4.4	0.7	1.8	1.9	0.8	1.7	1.9	1.7	1.6	1.5	1.8	1.9	1.7	1.7	1.3	1.7	1.6	0.6	0.8	2.1	1.5	0.9	1.7	-0.1	1.0	1.2
Neuroticism	1.6	3.8	7.6	0.2	2.2	2.8	2.5	2.5	2.4	2.3	2.5	2.7	2.1	2.5	2.5	2.4	1.4	1.9	1.9	0.2	-0.6	2.3	0.9	1.1	2.3	-0.9	0.4	0.5
Hand grip strength (right)	1.6	4.5	9.9	2.4	-2.0	-1.5	-1.7	-1.8	-1.7	-1.9	-1.9	-1.9	-2.3	-2.6	-1.9	-1.9	-2.1	-2.6	-2.2	-2.4	-1.8	-1.6	-2.8	-3.1	-1.8	-1.0	-2.8	-2.1
Loud music exposure frequency	1.6	1.7	4.4	-1.3	1.6	1.1	1.8	1.2	1.1	1.6	1.4	1.6	0.9	1.9	1.1	1.5	-0.2	1.6	2.1	1.0	0.5	1.1	1.0	1.5	0.9	0.7	1.1	1.1
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	9.6	0.9	-1.4	-0.6	-0.6	-0.8	-1.2	-1.5	-1.5	-1.4	-0.8	-1.7	-0.9	-1.5	1.6	-2.1	-2.0	-2.6	-2.0	-1.1	-3.0	-2.5	-0.3	-3.1	-2.3	-2.8
Shortness of breath walking on level ground	1.6	1.9	3.8	0.0	1.6	1.5	1.4	1.5	1.7	1.4	1.8	1.9	1.6	1.9	1.5	1.5	0.8	1.5	1.3	0.8	0.4	1.6	1.0	1.8	1.2	0.3	1.1	1.3
Alcohol intake frequency.	1.6	3.7	13.8	-1.6	0.4	0.7	0.7	-0.4	0.6	0.3	0.4	0.6	0.2	-0.3	-0.3	0.4	-1.7	1.4	1.0	3.6	3.4	0.5	2.9	2.8	-0.9	3.7	3.7	3.7
Depressed Affect (Nagel 2018)	1.5	3.1	7.7	0.3	1.7	2.8	2.0	2.4	2.0	1.7	2.0	2.1	1.9	1.9	2.3	1.8	2.3	1.1	1.1	-1.2	-1.8	2.1	0.1	-0.0	2.6	-1.9	-0.7	-0.4
Type 2 Diabetes (T2D) (2012)	1.5	1.7	3.9	1.9	1.2	1.9	1.0	1.6	1.4	1.3	1.5	1.1	1.3	2.0	1.5	1.4	1.6	0.8	0.7	-1.2	-1.7	1.0	-0.2	-0.1	1.3	-1.3	-0.6	-0.6
Ever had hysterectomy (womb removed)	1.5	1.7	7.9	-0.2	0.2	0.0	0.3	-0.4	0.2	0.3	0.5	0.6	-0.1	0.6	-0.2	0.4	-2.4	0.8	0.8	2.4	2.0	0.0	2.1	1.6	-1.0	2.8	2.0	2.1
Medication: Atenolol	1.5	1.8	4.3	-1.1	-1.8	-2.1	-1.7	-1.7	-1.4	-1.7	-1.6	-1.9	-1.3	-1.7	-1.6	-1.7	-0.2	-1.5	-1.4	-0.2	0.1	-1.3	-0.7	-0.8	-1.5	-0.2	-0.3	-0.9
Alcohol usually taken with meals	1.5	2.4	8.6	2.2	-0.3	-0.5	0.3	0.1	-0.5	-0.3	-0.2	0.3	-0.4	0.1	0.1	-0.3	0.6	-1.2	-1.0	-2.6	-2.9	-0.6	-2.6	-1.9	0.4	-2.8	-2.9	-2.8
Health satisfaction	1.5	1.9	5.5	-2.3	1.3	1.9	1.3	1.4	1.5	1.2	1.3	1.5	1.3	1.5	1.4	1.3	1.3	1.3	1.7	0.8	0.9	1.5	1.2	1.4	1.4	0.1	1.2	1.3
Commuting to job workplace: Car/motor vehicle	1.5	1.7	3.6	0.6	-1.6	-1.2	-1.5	-1.3	-1.3	-1.6	-1.7	-1.9	-1.6	-1.6	-1.4	-1.6	0.0	-1.7	-1.2	-0.8	-0.1	-1.2	-1.3	-1.8	-1.2	-0.5	-0.8	-0.8
Leg fat-free mass (right)	1.5	8.0	17.4	1.1	-3.4	-3.3	-4.2	-3.3	-3.3	-3.5	-3.4	-3.0	-3.6	-2.0	-3.0	-3.4	-1.6	-3.5	-3.2	-1.4	-1.0	-3.3	-2.4	-2.5	-3.0	-0.4	-1.8	-2.1
Leg predicted mass (right)	1.5	8.2	17.2	1.2	-3.4	-3.3	-4.1	-3.3	-3.3	-3.5	-3.4	-3.0	-3.6	-2.0	-3.0	-3.4	-1.6	-3.6	-3.3	-1.5	-1.1	-3.3	-2.5	-2.6	-3.0	-0.5	-1.9	-2.2
Coronary Artery Disease (CAD)	1.4	1.6	3.4	1.2	-1.4	-0.9	-1.7	-1.2	-1.4	-1.3	-1.2	-1.6	-1.4	-1.2	-0.9	-1.2	-0.8	-1.4	-1.8	-1.2	-1.0	-1.7	-0.7	-1.7	-1.0	-0.2	-1.3	-1.1
Allergy or Eczema	1.4	3.7	7.4	-2.4	1.9	1.5	2.0	1.8	1.7	2.0	2.0	1.9	2.4	2.0	1.9	2.0	1.3	2.3	2.0	1.8	1.6	1.7	2.2	2.7	1.6	0.2	2.3	1.2
Ever used hormone-replacement therapy (HRT)	1.4	1.8	7.3	-2.7	-1.4	-1.0	-1.7	-1.6	-1.2	-1.4	-1.2	-1.2	-1.2	-0.6	-1.4	-1.3	-1.3	-0.9	-0.8	1.5	2.3	-1.1	0.2	0.5	-1.8	1.0	1.3	0.3
Angina	1.4	1.8	5.1	-1.1	-1.7	-1.4	-1.4	-1.2	-1.5	-1.7	-1.5	-1.6	-1.5	-2.3	-1.2	-1.6	-0.1	-1.7	-1.6	-0.6	-0.4	-1.4	-0.9	-1.3	-0.9	-1.0	-0.5	-1.2
Leg fat-free mass (left)	1.4	7.6	15.8	1.4	-3.1	-3.3	-4.0	-3.0	-3.2	-3.3	-3.2	-2.9	-3.3	-1.9	-2.7	-3.2	-1.1	-3.5	-3.2	-1.9	-1.6	-3.1	-2.7	-2.8	-2.6	-0.9	-2.2	-2.5
Leg predicted mass (left)	1.4	7.6	16.0	1.6	-3.1	-3.2	-4.0	-3.0	-3.1	-3.2	-3.1	-2.8	-3.3	-1.8	-2.7	-3.2	-1.1	-3.5	-3.2	-1.9	-1.6	-3.1	-2.7	-2.8	-2.6	-1.0	-2.3	-2.5
Lung cancer (father)	1.4	1.7	5.4	0.8	-1.2	-1.1	-0.7	-1.7	-0.7	-1.2	-1.2	-1.1	-1.3	-1.1	-1.8	-1.2	-2.3	-0.9	-1.1	1.3	1.5	-0.7	0.7	-0.6	-1.9	2.2	0.9	1.3
Chronic bronchitis/emphysema (mother)	1.4	1.7	3.8	-2.0	1.3	0.8	1.0	1.7	1.4	1.2	1.4	1.2	1.6	1.2	1.5	1.3	1.7	1.3	1.4	0.5	0.5	1.5	1.3	1.0	1.8	-0.5	1.2	0.9
Angina (self-reported)	1.4	1.8	5.2	-1.2	-1.7	-1.4	-1.3	-1.1	-1.5	-1.8	-1.5	-1.6	-1.4	-2.3	-1.1	-1.7	0.1	-1.8	-1.6	-0.7	-0.5	-1.5	-1.0	-1.5	-0.7	-1.1	-0.6	-1.1
Illnesses of siblings: Diabetes	1.4	1.7	6.2	1.4	-0.1	0.2	-0.1	0.3	-0.5	-0.2	-0.3	-0.2	0.1	-0.5	0.2	-0.2	1.7	-0.9	-0.5	-2.5	-2.1	-0.4	-2.2	-1.5	0.8	-2.5	-2.3	-2.1
Whole body fat-free mass	1.4	8.2	14.7	1.3	-3.1	-3.2	-3.8	-3.1	-3.4	-3.3	-3.3	-2.9	-3.4	-2.2	-2.8	-3.3	-1.2	-3.6	-3.3	-2.0	-1.8	-3.3	-3.0	-2.8	-2.7	-1.1	-2.4	-2.7
Whole body water mass	1.4	8.0	14.7	1.2	-3.1	-3.2	-3.8	-3.1	-3.4	-3.3	-3.3	-2.9	-3.4	-2.1	-2.8	-3.3	-1.3	-3.5	-3.3	-1.9	-1.7	-3.3	-2.9	-2.7	-2.7	-1.0	-2.3	-2.6
Pain type(s) experienced in last month: Hip pain	1.4	1.7	5.8	1.0	1.3	1.3	1.3	1.6	1.2	1.1	1.1	1.3	1.5	0.9	1.5	1.1	2.4	0.6	0.8	-1.4	-1.5	1.3	-0.8	-0.5	2.0	-1.9	-1.1	-0.8
Ovarian Cancer	1.3	1.7	3.7	0.6	1.9	1.3	1.9	1.6	1.2	1.7	1.4	1.4	1.5	1.0	1.9	1.6	1.8	1.3	1.2	-0.7	-1.1	1.2	-0.1	0.3	1.7	-0.8	-0.5	-0.3
Trunk fat-free mass	1.3	7.6	12.0	1.2	-2.9	-3.1	-3.5	-2.9	-3.3	-3.1	-3.1	-2.7	-3.1	-2.4	-2.7	-3.1	-1.2	-3.4	-3.2	-2.1	-2.0	-3.3	-3.0	-2.6	-2.5	-1.3	-2.4	-2.9
Trunk predicted mass	1.3	7.4	12.0	1.1	-2.9	-3.1	-3.5	-2.9	-3.3	-3.1	-3.1	-2.7	-3.1	-2.3	-2.6	-3.1	-1.1	-3.4	-3.1	-2.0	-1.9	-3.3	-3.0	-2.5	-2.5	-1.3	-2.4	-2.9
Birth weight	1.3	2.8	5.2	-1.2	-2.0	-1.4	-2.3	-2.1	-1.9	-2.0	-2.1	-2.0	-1.8	-1.3	-2.0	-2.0	-2.2	-1.9	-1.7	-0.2	0.1	-1.8	-1.4	-1.2	-2.1	0.0	-0.4	-0.9
Leg pain on walking	1.3	1.6	3.3	0.6	1.4	1.2	1.3	1.7	1.2	1.3	1.3	1.4	1.4	1.3	1.8	1.3	1.7	0.9	0.8	-1.0	-1.5	1.2	-0.1	0.2	1.8	-1.4	-0.7	-0.7
Basal metabolic rate	1.3	7.3	14.4	1.3	-2.9	-3.1	-3.8	-3.0	-3.2	-3.1	-3.2	-2.8	-3.2	-2.0	-2.7	-3.1	-1.2	-3.3	-3.1	-1.8	-1.6	-3.1	-2.7	-2.7	-2.6	-0.9	-2.1	-2.4
Alcohol drinker status: Previous	1.3	1.5	5.2	-1.1	0.7	1.4	1.2	0.3	0.6	0.7	0.9	1.0	0.5	0.4	0.5	0.8	-0.8	1.2	1.2	1.8	1.3	0.5	1.2	2.3	-0.0	2.0	1.8	2.0
Arm predicted mass (left)	1.3	6.8	11.8	1.0	-2.7	-3.1	-3.4	-2.8	-3.2	-3.0	-3.1	-2.7	-3.0	-2.0	-2.6	-3.0	-1.2	-3.2	-3.0	-1.8	-1.7	-3.1	-2.7	-2.5	-2.5	-0.9	-2.1	-2.4
Alzheimer’s Disease (in father)	1.2	1.3	4.4	-0.7	0.2	0.5	-0.2	-0.1	0.6	0.3	0.4	0.5	0.2	1.3	0.1	0.4	-1.3	0.8	0.7	1.9	1.9	0.5	1.7	1.4	-0.5	2.0	2.0	2.1
Bipolar Disorder (2011)	1.2	1.2	3.3	-0.4	1.2	1.3	1.3	1.0	1.2	1.2	1.3	1.3	1.1	1.4	1.2	1.2	0.1	1.3	1.2	0.5	0.2	1.2	1.0	1.8	0.9	0.3	0.6	0.4
Maternal smoking around birth	1.2	1.7	6.7	-1.2	-0.8	-0.9	-1.0	-1.3	-0.7	-0.7	-0.7	-0.8	-1.0	-1.2	-0.8	-0.7	-2.6	-0.1	0.3	1.8	1.7	-0.7	1.9	0.7	-1.6	2.6	1.6	1.3
Qualifications: CSEs or equivalent	1.2	1.5	4.6	-0.5	-1.4	-1.5	-1.6	-1.3	-1.6	-1.6	-1.6	-1.6	-1.5	-2.2	-1.3	-1.6	-0.1	-1.3	-1.3	-0.2	-0.3	-1.6	-0.3	-0.6	-1.1	-0.1	0.1	-0.8
Sitting height	1.2	8.7	17.0	1.3	-2.9	-2.4	-2.3	-2.8	-3.3	-3.1	-2.9	-2.5	-3.1	-3.0	-2.8	-3.1	-1.5	-3.8	-3.2	-3.0	-2.9	-3.3	-3.8	-3.0	-2.5	-2.3	-3.3	-4.1
Medication: Simvastatin	1.2	1.7	4.0	-1.0	-1.4	-1.3	-1.3	-1.7	-2.0	-1.6	-1.7	-1.7	-1.6	-1.5	-1.6	-1.6	-0.9	-1.1	-1.2	0.6	0.7	-2.0	0.1	-0.0	-1.6	0.7	0.6	-0.2
Weight	1.2	5.9	14.7	1.2	-2.7	-2.7	-3.8	-2.8	-2.8	-2.8	-3.0	-2.8	-2.9	-1.8	-2.5	-2.9	-1.1	-2.9	-2.9	-1.3	-1.0	-2.7	-2.1	-2.4	-2.4	-0.3	-1.6	-1.7
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	3.5	-0.6	1.7	0.9	1.5	1.6	1.8	1.8	1.7	1.5	1.5	1.7	1.5	1.8	0.9	1.9	1.6	0.7	0.5	1.8	0.9	1.2	1.5	0.3	0.9	1.2
Arm fat-free mass (right)	1.2	6.0	9.6	0.9	-2.5	-2.6	-3.1	-2.6	-2.9	-2.8	-2.8	-2.4	-2.7	-2.0	-2.4	-2.8	-0.9	-3.1	-2.9	-1.9	-1.8	-2.8	-2.8	-2.5	-2.2	-1.1	-2.2	-2.4
Comparative body size at age 10	1.2	3.4	7.5	-1.2	1.7	1.3	0.5	2.0	1.9	1.7	2.2	2.2	2.3	2.7	2.1	1.9	1.9	2.1	1.9	1.2	1.1	1.8	1.8	2.5	1.9	0.7	1.5	2.1
Had major operations	1.2	1.4	3.3	0.9	1.5	0.2	1.8	1.3	1.5	1.5	1.2	1.1	1.3	1.8	1.4	1.4	1.3	1.3	1.4	-0.1	-0.7	1.6	0.2	0.5	1.3	-0.9	0.1	-0.1
Arm fat-free mass (left)	1.2	6.3	10.5	1.1	-2.6	-2.9	-3.2	-2.8	-3.0	-2.9	-2.9	-2.6	-3.0	-2.0	-2.6	-2.9	-1.4	-3.1	-2.9	-1.6	-1.7	-3.0	-2.5	-2.3	-2.5	-0.6	-2.0	-2.2
HbA1C	1.1	1.2	2.8	0.5	1.7	1.5	1.3	1.3	1.2	1.6	1.4	1.0	1.3	1.1	1.1	1.5	0.7	1.5	1.2	0.3	-0.2	1.0	0.6	0.9	0.8	0.5	0.4	0.7
Hypothyroidism (self reported)	1.1	2.4	9.8	1.6	-0.3	0.3	0.6	0.1	-0.3	-0.5	-0.5	-0.2	0.2	-1.0	0.2	-0.5	2.0	-1.2	-1.1	-2.8	-2.5	-0.2	-2.9	-2.1	0.7	-3.1	-2.5	-2.4
Average weekly spirits intake	1.1	1.3	2.6	0.7	1.5	1.6	0.6	1.3	1.2	1.4	1.1	1.0	1.5	1.6	1.5	1.3	1.4	1.2	1.6	-0.5	-0.0	1.2	-0.6	0.3	1.4	-1.1	-0.3	-0.2
Severe depression (siblings)	1.1	1.2	3.4	-1.3	0.6	1.8	0.9	1.3	0.7	0.5	1.4	1.5	1.3	0.7	1.3	0.8	0.9	0.1	-0.1	-1.1	-1.4	0.6	-1.5	0.6	1.2	-1.7	-0.8	-0.8
Number of children fathered	1.1	1.2	5.0	2.1	-0.6	-0.3	-0.9	-0.4	-0.4	-0.6	-0.7	-0.5	-0.5	0.0	-0.4	-0.6	0.4	-1.1	-0.9	-1.9	-1.7	-0.4	-1.8	-1.7	-0.2	-1.2	-2.2	-1.6
Arm predicted mass (right)	1.1	5.5	8.8	1.0	-2.4	-2.5	-3.0	-2.4	-2.8	-2.6	-2.6	-2.3	-2.6	-1.9	-2.2	-2.7	-1.0	-3.0	-2.7	-1.9	-2.0	-2.7	-2.7	-2.4	-2.0	-1.1	-2.2	-2.5
Mother’s age at death	1.1	1.3	4.7	0.9	1.1	0.4	0.4	1.4	1.3	1.2	1.3	1.4	1.7	2.2	1.4	1.2	0.7	0.7	0.8	-1.0	-1.5	1.4	-0.6	-0.1	1.5	-1.0	-1.0	-0.1
Financial situation satisfaction	1.1	1.3	4.1	-0.6	1.1	1.7	1.1	1.6	1.1	0.9	1.0	0.9	1.3	0.9	1.3	0.9	2.0	0.5	0.7	-1.3	-1.3	1.1	-0.1	-0.4	1.9	-1.5	-0.7	-0.3
Age started oral contraceptive pill	1.1	1.4	3.0	-0.2	-1.5	-1.5	-1.7	-1.3	-1.5	-1.5	-1.5	-1.6	-0.8	-0.2	-1.5	-1.5	-0.4	-1.4	-1.5	-0.5	-0.2	-1.4	-1.4	-1.0	-1.1	-0.0	-0.7	-0.5
Myopia	1.1	1.6	3.5	-1.5	-1.4	-1.5	-1.1	-1.4	-1.6	-1.5	-1.5	-1.5	-1.4	-1.9	-1.5	-1.5	-1.1	-1.4	-1.3	-0.4	0.1	-1.6	-0.7	-0.6	-1.4	-0.1	-0.2	-0.7
Townsend deprivation index at recruitment	1.0	1.5	5.2	-1.6	-1.0	-1.7	-0.7	-1.3	-1.0	-1.0	-0.8	-1.1	-0.7	-1.3	-1.3	-0.9	-2.3	-0.5	-0.5	1.4	2.1	-1.0	0.3	0.5	-1.5	1.4	1.1	1.0
Medication: Levothyroxine sodium	1.0	1.7	6.7	0.1	-0.8	-0.4	-0.3	-0.3	-0.9	-0.8	-0.9	-0.8	-0.3	-1.0	-0.3	-0.9	1.8	-1.2	-1.3	-2.1	-1.6	-0.7	-2.3	-1.4	0.3	-2.6	-1.9	-2.3
Had menopause	1.0	1.3	2.9	0.3	-1.2	-1.0	-1.3	-0.9	-0.9	-1.2	-0.9	-0.8	-0.8	-1.1	-1.0	-1.1	-0.7	-1.5	-1.5	-1.2	-0.9	-0.8	-1.7	-1.5	-0.8	-1.2	-1.4	-1.5
Ever had bowel cancer screening	1.0	1.2	4.6	1.0	1.1	0.9	0.9	1.2	1.6	1.2	1.2	1.2	1.4	2.1	1.4	1.2	1.2	1.0	1.2	-0.1	-0.3	1.6	0.3	0.5	1.1	-0.8	-0.1	0.0
Ever depressed for a whole week	1.0	1.2	3.5	0.2	1.4	1.3	0.8	1.4	1.2	1.4	1.2	1.1	1.4	1.9	1.2	1.3	1.4	1.2	1.0	-0.3	-0.2	1.3	0.4	0.2	1.5	-0.5	-0.1	0.1
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	4.9	-0.3	0.1	-0.6	0.2	-0.5	0.0	0.2	0.3	0.4	-0.3	-0.1	-0.1	0.2	-2.1	0.7	0.7	2.2	1.8	-0.1	2.0	1.8	-0.9	2.1	2.0	1.5
Prostate Cancer	0.9	1.2	2.6	-0.9	-1.3	-1.6	-1.0	-1.4	-1.3	-1.4	-1.0	-1.1	-1.2	-1.1	-1.2	-1.3	-1.5	-1.0	-1.0	0.9	1.0	-1.3	0.5	0.3	-1.4	0.7	0.7	-0.2
Schizophrenia (2014)	0.9	2.0	6.4	-1.2	0.6	1.4	0.6	-0.2	0.7	0.7	0.6	0.7	0.0	1.1	0.2	0.7	-1.6	1.2	0.9	2.5	2.1	0.4	2.3	2.5	-0.7	2.4	2.2	1.7
Trunk fat mass	0.9	3.9	12.2	0.7	-2.2	-2.1	-3.5	-2.3	-2.2	-2.3	-2.6	-2.5	-2.2	-1.2	-2.1	-2.4	-0.8	-2.3	-2.4	-0.7	-0.2	-2.1	-1.6	-2.0	-2.0	-0.0	-0.9	-1.0
Hip circumference	0.9	3.9	11.8	1.1	-2.3	-1.9	-3.4	-2.2	-2.3	-2.4	-2.4	-2.3	-2.4	-1.5	-2.1	-2.4	-0.9	-2.4	-2.3	-1.0	-0.6	-2.2	-1.6	-2.0	-2.0	-0.1	-1.2	-1.2
Alcohol intake versus 10 years previously	0.9	1.4	4.4	-0.1	-1.2	-0.9	-1.0	-1.4	-0.5	-1.3	-1.2	-1.2	-1.2	-1.1	-1.5	-1.2	-1.0	-0.8	-0.9	1.1	1.5	-0.5	0.9	-0.3	-1.6	2.1	0.9	1.8
Number of live births	0.9	1.2	2.7	0.7	-1.3	-1.6	-0.7	-1.5	-1.4	-1.3	-1.5	-1.2	-1.2	-0.8	-1.4	-1.4	-1.0	-1.2	-1.5	-0.0	-0.3	-1.3	-0.4	-0.5	-1.5	0.2	-0.3	-0.8
Medication: Cholesterol lowering	0.9	1.4	2.5	0.7	-1.2	-0.8	-1.0	-0.9	-1.5	-1.3	-1.2	-1.2	-1.1	-1.5	-0.9	-1.3	0.1	-1.5	-1.1	-1.3	-1.1	-1.6	-1.0	-1.3	-0.6	-1.0	-1.3	-1.6
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	3.0	0.7	0.9	1.4	0.9	1.3	0.9	1.0	1.0	1.1	1.2	1.6	1.3	1.0	1.7	0.6	0.9	-0.9	-1.2	0.9	-0.3	0.3	1.4	-1.5	-0.8	-0.8
Blood clot in the leg (DVT)	0.9	1.2	4.6	0.4	0.1	-0.5	0.3	-0.4	0.1	0.2	0.3	0.5	-0.3	0.0	-0.1	0.3	-2.0	0.7	0.7	2.0	1.6	0.0	1.8	1.4	-0.8	2.1	1.7	1.5
Chest pain or discomfort	0.9	1.2	2.7	0.4	1.4	1.4	1.4	1.5	1.3	1.3	1.4	1.3	1.2	0.6	1.6	1.3	0.7	0.9	0.6	-0.6	-1.1	1.4	0.4	0.3	1.6	-1.0	-0.3	-0.3
Illnesses of father: Heart disease	0.9	1.3	4.7	-1.0	1.2	0.5	1.1	0.7	0.7	1.2	0.8	1.1	1.1	0.2	0.7	1.1	-0.3	1.6	1.2	1.8	1.3	0.6	1.4	2.2	0.5	0.8	1.7	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	5.6	-1.2	-1.3	-1.9	-1.4	-1.6	-2.0	-1.4	-1.7	-1.5	-1.3	-2.4	-1.4	-1.5	-1.0	-1.2	-0.9	0.2	0.6	-2.1	-1.2	-0.5	-1.7	0.3	0.2	-0.4
Hearing aid user	0.9	1.0	2.7	-0.2	1.1	1.2	0.3	1.3	1.3	1.1	1.4	1.1	0.9	1.6	1.0	1.2	0.8	1.1	1.2	0.3	0.4	1.3	0.9	1.0	1.1	-0.5	0.4	0.1
Crohns Disease (2012)	0.8	1.2	4.6	-0.5	1.1	0.7	0.8	1.0	1.4	1.1	1.3	1.3	1.1	2.2	1.2	1.2	0.0	1.2	1.1	1.0	1.0	1.3	0.8	1.6	0.6	0.2	1.2	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.5	-1.2	0.9	1.4	1.2	1.4	1.3	0.9	1.6	1.5	1.0	1.1	1.4	1.1	0.9	0.7	0.7	-0.1	-0.4	1.2	0.5	0.8	1.3	-0.5	0.3	0.5
Relative age voice broke	0.8	1.3	5.7	-0.4	-1.1	-1.4	-0.6	-1.5	-1.0	-0.9	-1.2	-0.9	-1.1	-1.1	-1.3	-1.0	-2.4	-0.7	-0.7	1.2	0.9	-1.0	0.4	-0.1	-1.6	1.6	0.7	0.6
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	7.3	2.7	-0.1	0.0	-0.1	0.5	0.6	0.1	0.2	0.3	0.2	-0.1	0.4	0.1	0.6	-0.5	-0.4	-1.4	-1.2	0.7	-1.0	-1.4	0.6	-1.6	-1.4	-1.3
Allergy	0.8	1.7	6.1	2.5	-1.1	-0.8	-1.1	-0.8	-0.7	-1.0	-1.0	-1.0	-1.2	-1.3	-1.0	-1.0	-0.7	-1.5	-1.4	-1.7	-1.5	-0.7	-1.7	-2.3	-0.6	-0.5	-2.2	-0.9
Number of full brothers	0.8	1.0	2.3	-0.3	-0.6	-1.5	-0.4	-1.3	-1.0	-0.9	-1.2	-1.4	-0.8	-1.2	-1.2	-1.0	-1.4	-0.6	-1.1	0.8	0.8	-0.9	0.3	-0.2	-1.4	1.2	0.8	0.3
Whole body fat mass	0.8	3.2	10.7	0.7	-2.0	-1.9	-3.3	-2.0	-2.0	-2.1	-2.4	-2.4	-2.1	-1.1	-1.9	-2.2	-0.7	-2.1	-2.2	-0.7	-0.3	-1.9	-1.5	-2.0	-1.7	-0.1	-0.9	-0.9
Pulse rate, automated reading	0.8	2.5	4.8	-1.4	1.6	1.5	1.2	1.5	1.7	1.6	1.5	1.3	1.6	1.1	1.5	1.6	1.4	2.0	1.6	1.6	1.2	1.8	2.0	1.5	1.3	1.3	1.8	2.2
Pain experienced in last month	0.8	1.3	2.9	0.1	1.0	0.8	0.3	1.1	1.1	1.2	1.3	1.2	1.5	1.3	0.9	1.2	0.8	1.5	1.4	1.2	0.9	1.1	1.2	1.6	0.9	0.9	1.3	1.7
Bipolar Disorder or Schizophrenia	0.7	1.6	7.1	-1.8	0.9	1.2	0.9	0.3	0.5	0.9	0.7	0.9	0.2	1.1	0.6	0.9	-0.7	1.4	1.2	1.9	1.4	0.3	2.0	2.7	0.1	1.6	1.9	1.2
Schizophrenia (2018)	0.7	1.5	5.1	-1.5	0.4	0.8	0.5	-0.1	0.5	0.4	0.5	0.4	-0.0	0.4	0.1	0.5	-1.3	1.0	0.7	2.2	2.0	0.4	2.2	2.2	-0.5	2.0	2.1	1.3
Alzheimer’s Disease (including proxy)	0.7	1.0	3.1	-0.4	-1.2	-0.8	-1.3	-1.3	-0.5	-1.1	-1.2	-1.1	-1.3	-1.0	-1.3	-1.1	-1.8	-0.9	-1.3	0.8	1.2	-0.6	0.1	-0.4	-1.3	0.8	0.3	0.2
Irritable Bowel Disease (IBD)	0.7	1.7	5.8	-0.7	0.9	1.7	0.2	0.9	1.5	0.9	1.3	1.2	1.4	1.9	1.2	1.1	0.6	1.4	1.1	1.2	1.2	1.4	1.1	1.9	0.7	1.2	1.8	2.4
Ulcerative Colitis (UC)	0.7	1.2	4.5	0.1	0.9	1.6	0.5	0.8	1.2	0.9	1.1	0.9	1.1	1.0	1.0	1.0	0.6	1.3	1.2	0.9	1.0	1.2	1.0	1.5	0.7	1.1	1.4	2.1
Pack years adult smoking proportion	0.7	1.1	2.5	0.4	1.3	0.9	0.7	1.0	1.2	1.4	1.0	0.8	0.9	0.3	1.2	1.2	-0.0	1.5	1.6	1.1	1.2	1.2	1.3	0.8	0.7	0.7	1.1	1.1
Fed-up feelings	0.7	1.3	4.1	0.9	1.2	2.0	1.0	1.5	1.2	1.2	1.2	1.5	1.1	1.0	1.5	1.2	1.1	0.7	0.8	-0.6	-1.2	1.3	0.0	-0.3	1.6	-1.1	-0.3	-0.2
Multivitamins +/- minerals	0.7	0.9	1.8	0.4	1.0	0.6	0.8	1.0	0.9	1.1	1.1	1.0	1.0	0.2	1.0	1.1	0.4	1.3	1.4	1.0	0.8	0.8	1.0	1.3	0.9	0.7	1.1	1.1
Number of incorrect matches in round	0.7	1.2	2.3	0.2	1.3	1.4	1.1	1.0	1.1	1.2	1.2	1.5	1.1	1.0	0.9	1.2	-0.2	1.3	1.2	1.3	0.7	1.0	1.0	1.1	0.6	1.2	1.0	1.5
Arm fat mass (right)	0.7	3.1	11.6	0.4	-2.0	-2.1	-3.4	-2.1	-2.0	-2.1	-2.4	-2.3	-2.1	-1.0	-1.8	-2.2	-0.7	-1.9	-2.1	-0.4	0.2	-1.9	-1.2	-1.6	-1.8	0.3	-0.5	-0.4
Migraine (self-reported)	0.7	0.8	2.9	-0.2	-1.0	-1.1	-0.4	-1.0	-0.8	-1.1	-1.1	-1.1	-1.0	-1.7	-1.0	-1.1	-0.6	-1.1	-1.2	-0.4	-0.4	-0.8	-0.6	-1.1	-0.9	0.3	-0.4	-0.0
Back pain experienced in last month	0.7	1.0	4.4	0.4	0.7	0.9	1.0	0.6	-0.2	0.5	0.1	0.1	0.3	0.3	0.7	0.3	0.6	-0.1	0.2	-1.7	-1.9	-0.2	-1.2	-1.1	0.9	-1.9	-1.7	-2.1
Breast cancer (self-reported)	0.7	0.8	4.0	2.0	0.7	0.9	0.7	0.8	1.5	0.8	1.0	1.1	0.4	0.6	1.2	0.9	-0.3	0.5	0.6	-0.5	-0.7	1.6	0.2	-0.4	0.7	-0.0	-0.8	0.5
Arm fat mass (left)	0.7	3.0	11.4	0.5	-2.0	-2.0	-3.4	-2.1	-2.0	-2.1	-2.3	-2.3	-2.1	-0.9	-1.9	-2.2	-0.8	-1.9	-2.1	-0.2	0.2	-1.9	-1.0	-1.5	-1.9	0.4	-0.4	-0.4
Average weekly champagne plus white wine intake	0.7	0.9	3.2	0.6	-0.5	-0.6	-0.6	-0.1	-0.6	-0.5	-0.3	-0.4	-0.5	1.4	-0.2	-0.4	0.0	-0.9	-1.2	-1.4	-1.3	-0.6	-1.7	-1.1	0.1	-1.7	-1.4	-1.8
Ever smoked	0.7	1.3	5.8	-0.9	0.1	-0.0	-0.3	0.6	0.4	0.0	0.1	-0.0	-0.0	-0.2	0.5	0.0	2.1	-0.6	-0.6	-1.9	-1.9	0.5	-1.8	-1.2	0.9	-2.4	-1.8	-1.7
Pack years of smoking	0.7	1.0	2.4	0.3	1.2	0.7	0.5	1.0	1.1	1.4	1.0	0.8	0.9	0.3	1.1	1.2	-0.1	1.5	1.6	1.2	1.1	1.1	1.3	0.9	0.6	0.7	1.1	1.1
LDL Cholesterol	0.6	1.0	2.4	-1.0	1.1	0.1	0.8	0.7	1.2	1.0	0.9	0.8	0.7	1.2	0.9	1.1	0.2	1.3	1.3	1.0	1.2	1.1	1.2	1.6	0.4	0.7	0.7	1.1
Lung FVC	0.6	3.2	15.8	-0.1	-1.3	-1.5	-1.2	-2.2	-1.8	-1.2	-1.7	-1.5	-1.7	-2.3	-1.9	-1.4	-4.0	-0.6	-1.4	2.0	2.1	-1.9	0.6	0.3	-2.5	2.4	1.5	0.8
Trunk fat percentage	0.6	2.4	8.8	0.7	-1.8	-1.6	-3.0	-1.8	-1.6	-1.8	-2.1	-2.1	-1.8	-0.8	-1.8	-1.9	-0.7	-1.7	-1.9	-0.3	0.3	-1.5	-1.0	-1.7	-1.6	0.4	-0.5	-0.3
Fluid intelligence score	0.6	1.3	4.0	1.0	-0.6	0.3	-0.9	-0.4	-1.0	-0.6	-0.8	-0.7	-0.4	-0.3	-0.5	-0.6	0.6	-1.0	-0.8	-1.9	-2.0	-1.0	-2.0	-1.6	-0.1	-1.6	-2.0	-2.0
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.9	-1.1	0.2	0.5	1.0	-0.1	0.3	0.2	0.6	0.4	0.2	-0.4	-0.1	0.3	-0.7	0.6	0.2	1.4	1.2	0.2	1.7	1.5	-0.3	1.7	1.5	1.2
Illnesses of mother	0.6	0.8	1.8	0.8	-1.0	-0.7	-0.4	-0.8	-0.6	-0.9	-0.7	-0.9	-0.9	-1.0	-0.9	-0.8	-0.6	-1.1	-1.0	-1.1	-0.5	-0.6	-0.8	-1.2	-0.6	-0.6	-1.3	-1.2
Pulse wave Arterial Stiffness index	0.6	0.7	2.6	1.2	-0.4	-0.3	-0.3	-0.2	-0.6	-0.3	-0.4	-0.3	-0.4	-0.4	-0.2	-0.4	0.5	-0.7	-0.7	-1.4	-1.5	-0.5	-1.4	-1.2	0.1	-0.7	-1.6	-1.1
Length of working week for main job	0.6	0.7	3.0	-0.1	1.0	0.9	0.9	0.7	0.8	1.0	0.7	0.9	0.7	0.7	0.8	0.9	-0.1	1.1	0.8	0.7	0.5	0.8	0.5	0.5	0.7	1.1	0.9	1.7
Breastfed as a baby	0.6	0.8	2.2	0.0	-1.0	-0.8	-1.5	-1.1	-0.9	-1.0	-0.9	-0.9	-1.1	-1.2	-1.0	-1.0	-0.8	-0.9	-0.6	-0.2	-0.4	-0.9	-0.8	-0.3	-1.2	-0.1	-0.3	-0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.2	1.5	0.4	0.9	0.5	0.9	0.6	0.4	0.9	0.9	0.4	1.4	0.8	0.6	1.3	0.2	0.3	-1.1	-1.4	0.6	-0.5	0.3	1.1	-1.0	-0.9	-0.6
Medication: Seretide 50 evohaler	0.6	0.6	4.1	-0.9	0.3	0.6	-0.1	0.8	0.3	0.2	0.4	0.3	0.7	0.8	0.8	0.2	2.0	0.0	0.3	-0.9	-0.8	0.3	-0.9	-0.0	1.2	-1.7	-0.5	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	2.6	-0.2	1.0	0.3	1.0	0.6	0.6	1.0	0.7	0.7	0.7	1.1	0.5	0.9	-0.0	1.2	1.0	1.2	1.6	0.6	0.6	1.0	0.5	0.7	1.1	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.1	0.3	1.0	1.0	0.9	0.7	0.7	0.9	1.1	0.9	0.8	1.4	0.9	0.9	-0.5	1.0	0.8	0.3	0.3	0.7	0.7	1.4	0.6	0.2	0.3	0.1
Illnesses of father: None of the above (group 1)	0.6	0.7	1.6	0.1	-1.1	-0.8	-0.5	-0.6	-0.8	-1.0	-0.7	-0.9	-0.9	-0.1	-0.8	-0.9	0.1	-1.2	-1.1	-1.1	-1.1	-0.7	-0.2	-1.2	-0.4	-0.2	-1.1	-0.9
Risk taking	0.6	0.9	1.8	0.7	-0.7	-0.8	-0.4	-0.8	-0.7	-0.6	-0.9	-0.8	-1.0	-1.2	-0.9	-0.7	-1.1	-1.0	-1.0	-0.9	-1.0	-0.6	-1.1	-1.3	-0.8	-0.7	-1.3	-1.3
Cholesterol lowering medication	0.6	0.9	3.3	-1.8	-0.2	-0.8	-0.3	-0.7	-0.4	-0.3	-0.5	-0.5	-0.4	0.2	-0.5	-0.4	-0.5	0.3	-0.1	1.6	1.6	-0.4	1.2	1.0	-0.8	1.6	1.6	1.3
Alzheimer’s Disease (in mother)	0.5	0.6	2.8	-0.1	-0.6	-0.6	-0.7	-1.0	-0.2	-0.6	-0.7	-0.5	-1.1	-0.9	-0.9	-0.6	-1.7	-0.4	-0.9	0.9	1.1	-0.2	0.1	-0.0	-1.2	1.0	0.3	0.4
Blood White Count	0.5	3.4	6.8	-0.2	2.2	2.0	2.1	2.5	1.9	2.1	2.0	2.1	2.3	2.4	2.6	2.1	2.5	1.7	1.3	-0.9	-1.0	2.0	-0.2	0.7	2.6	-1.6	-0.4	-0.2
Systolic Blood Pressure	0.5	2.5	5.5	0.1	-1.8	-1.8	-1.4	-1.9	-1.7	-1.8	-2.1	-2.3	-1.7	-2.2	-2.0	-1.9	-2.0	-1.4	-1.3	0.6	0.9	-1.6	0.4	-1.3	-1.8	1.0	0.4	0.1
Number of treatments/medications taken	0.5	1.0	1.8	-0.5	1.2	1.4	1.2	1.0	1.2	1.1	1.2	1.2	1.1	0.1	1.3	1.1	0.6	1.1	1.0	0.5	0.4	1.3	1.0	1.0	1.0	-0.1	0.8	0.6
Vitamin and mineral supplements	0.5	0.7	1.5	-0.9	-1.1	-0.6	-1.0	-0.9	-0.9	-1.0	-1.0	-1.0	-0.9	0.2	-0.9	-1.0	-0.1	-1.0	-1.2	-0.7	-0.3	-0.9	-0.7	-0.9	-0.7	-0.5	-0.7	-0.9
Average weekly fortified wine intake	0.5	0.6	1.5	-0.4	-0.6	-0.6	-0.7	-0.6	-0.9	-0.7	-0.5	-0.5	-0.8	-1.2	-0.8	-0.7	-1.2	-0.8	-0.4	-0.7	-0.3	-1.0	-1.0	-0.3	-0.6	-0.7	-0.8	-1.2
Hayfever, allergic rhinitis or eczema	0.5	1.1	3.8	-2.0	0.9	0.8	1.1	0.7	0.8	0.9	0.8	0.8	1.0	0.9	0.8	0.9	0.5	1.2	1.0	1.3	1.4	0.8	1.4	1.5	0.5	0.1	1.6	0.5
Pain all over the body in last month	0.5	0.6	1.7	1.1	0.4	1.1	0.3	0.7	0.3	0.4	0.5	0.4	0.3	-0.4	0.7	0.4	1.3	-0.0	-0.1	-1.2	-0.9	0.3	-0.8	-0.5	0.9	-1.2	-1.2	-0.8
Medication: Ramipril	0.5	0.7	3.1	-1.8	-0.9	-0.6	-0.7	-0.8	-0.9	-1.0	-0.9	-0.8	-0.8	-1.6	-0.7	-1.0	0.3	-0.7	-0.8	0.7	0.5	-0.8	0.5	0.0	-0.7	0.3	0.7	0.2
Time employed in main current job	0.5	0.6	1.5	0.8	0.8	0.8	-0.0	1.0	1.0	0.9	0.7	0.4	0.8	0.6	1.0	0.8	1.2	0.8	1.1	0.1	0.3	1.0	0.9	-0.5	1.2	0.1	0.1	0.8
Medication: Lansoprazole	0.5	0.6	2.3	0.6	0.7	1.2	0.9	0.9	1.4	0.6	0.9	0.7	0.8	0.4	1.0	0.7	0.8	0.4	0.3	-0.4	-0.8	1.5	0.4	0.2	1.0	-0.7	-0.4	-0.2
Peak expiratory flow (PEF)	0.5	1.2	3.7	0.6	-1.1	-1.5	-1.1	-1.5	-0.8	-1.1	-1.1	-0.8	-1.6	-1.1	-1.2	-1.1	-1.9	-1.1	-1.4	0.1	0.3	-0.8	-0.4	-0.8	-1.7	0.8	-0.2	-0.0
Commuting to job workplace: Public transport	0.5	0.6	3.1	-0.7	0.8	1.1	0.4	0.7	0.5	0.8	0.8	0.8	0.9	1.8	0.8	0.8	0.8	0.9	0.7	0.6	-0.3	0.4	0.9	1.0	0.6	0.2	0.8	0.3
Supplements: Fish oil (including cod liver oil)	0.5	0.6	4.7	2.2	1.0	1.0	0.9	0.6	0.5	1.0	0.8	0.8	0.7	0.0	0.5	0.9	-0.4	0.8	0.9	0.0	-0.3	0.5	0.8	0.3	0.6	-0.1	-0.2	-0.5
Medication: Bendroflumethiazide	0.5	0.7	1.7	0.3	-1.0	-0.7	-0.3	-0.9	-1.3	-1.1	-1.0	-0.9	-0.8	-1.0	-0.9	-1.1	-0.7	-1.0	-1.1	-0.4	-0.6	-1.3	-0.6	-0.7	-0.8	0.4	-0.6	-0.4
Medication: Lisinopril	0.5	0.6	1.2	-0.2	-0.9	-0.4	-0.5	-0.9	-1.1	-1.1	-0.8	-0.7	-1.1	-0.8	-1.0	-1.0	-0.9	-0.9	-1.1	-0.2	-0.6	-1.1	-0.4	-0.1	-0.7	0.1	-0.2	-0.7
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.0	-0.3	-0.8	-0.4	-1.1	-0.2	-0.5	-0.9	-0.6	-0.7	-0.5	-1.2	-0.1	-0.7	1.0	-1.0	-1.0	-0.8	-0.8	-0.5	-0.6	-0.9	0.0	-1.4	-0.5	-1.1
Leg fat mass (left)	0.5	1.9	6.9	0.4	-1.5	-1.5	-2.6	-1.6	-1.4	-1.7	-1.9	-1.8	-1.6	-0.9	-1.4	-1.7	-0.6	-1.5	-1.7	-0.3	-0.1	-1.3	-1.0	-1.4	-1.4	0.2	-0.4	-0.3
Bipolar Disorder (2018)	0.4	0.6	2.1	-1.1	0.9	0.9	0.7	0.7	0.2	0.9	0.6	0.9	0.4	1.1	0.8	0.8	0.4	1.0	1.0	0.3	-0.2	0.1	0.5	1.4	0.7	0.2	0.5	0.2
Lupus	0.4	0.6	2.0	-1.0	-0.5	-0.6	-0.4	-0.8	-0.6	-0.6	-0.4	-0.3	-0.6	-0.4	-0.5	-0.6	-0.8	-0.3	-0.6	1.1	1.4	-0.7	0.1	0.8	-0.9	1.0	1.2	1.0
Heel T-Score	0.4	3.1	12.1	1.0	2.2	1.9	2.1	1.9	1.5	2.1	2.0	2.2	1.9	3.5	2.1	2.1	1.3	2.0	1.6	-0.2	-1.2	1.5	0.6	1.4	2.0	0.0	0.1	0.6
Chronotype (morning person)	0.4	1.0	2.2	1.0	1.1	1.0	1.1	1.2	1.4	1.1	0.9	0.9	1.2	0.2	1.1	1.1	1.5	0.8	1.0	-0.7	-0.9	1.4	-0.2	-0.4	1.4	-0.5	-0.8	0.3
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.3	-0.1	0.6	0.6	0.6	1.0	1.0	0.7	1.0	1.1	0.7	0.7	1.1	0.8	0.8	0.6	0.9	0.0	-0.1	0.9	-0.1	0.4	0.9	-0.3	0.3	0.4
Medication: Metformin	0.4	0.5	2.6	0.4	0.9	1.2	0.3	0.6	0.5	0.6	0.5	0.7	0.6	1.2	0.8	0.6	1.6	0.8	0.8	0.2	-0.2	0.6	0.4	0.8	0.7	0.1	0.6	0.6
Diabetes (mother)	0.4	0.5	1.8	0.0	-0.4	-0.0	-0.2	-0.3	-1.0	-0.4	-0.6	-0.6	-0.6	-0.8	-0.2	-0.5	1.0	-0.6	-0.1	-0.8	-1.0	-1.0	-1.3	-0.5	0.0	-1.0	-0.5	-1.0
Serious illness, injury or assault to yourself	0.4	0.4	1.1	-1.0	0.7	0.3	0.5	0.8	0.8	0.7	0.7	0.8	0.6	0.7	0.7	0.7	0.4	0.6	1.0	0.3	0.7	0.8	0.4	0.7	0.7	-0.4	0.4	0.4
Nervous feelings	0.4	0.7	2.4	-0.3	0.5	0.2	0.6	0.0	0.8	0.5	0.6	0.6	0.3	0.7	0.1	0.5	-0.3	0.8	0.4	1.5	1.0	0.8	1.4	1.3	-0.3	1.6	1.4	1.5
Arm fat percentage (right)	0.4	1.6	8.3	0.0	-1.4	-1.4	-2.9	-1.5	-1.3	-1.4	-1.7	-1.8	-1.4	-0.4	-1.3	-1.5	-0.5	-1.0	-1.4	0.5	1.0	-1.2	-0.2	-0.9	-1.3	0.9	0.4	0.5
Falls in the last year	0.4	0.5	2.0	-1.1	0.3	-0.1	-0.1	0.2	0.5	0.3	0.5	0.4	0.3	0.5	0.3	0.4	-0.1	0.6	0.6	1.0	1.4	0.5	1.0	1.0	0.2	0.9	1.1	1.2
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.3	-0.4	0.3	1.2	0.3	1.0	1.3	0.6	1.1	0.8	0.7	0.1	1.0	0.8	0.9	0.7	0.8	0.3	0.6	1.3	0.7	0.2	0.9	0.5	0.6	1.5
Age at first live birth	0.4	0.7	1.8	0.1	-0.7	-0.5	-0.8	-0.3	-0.9	-0.5	-0.9	-0.6	0.1	-0.7	-0.3	-0.6	1.3	-0.6	-0.2	-1.3	-1.0	-0.9	-1.3	-0.7	0.2	-1.1	-1.2	-1.0
Emphysema/chronic bronchitis	0.4	0.5	2.0	-1.4	-0.8	-0.6	-0.6	-0.7	-1.0	-1.0	-0.5	-0.6	-0.6	-0.4	-0.7	-0.9	0.3	-0.7	-0.8	0.2	0.6	-1.0	0.2	0.4	-0.7	0.2	0.5	-0.2
Leg fat mass (right)	0.4	1.7	6.3	0.6	-1.4	-1.5	-2.5	-1.5	-1.4	-1.6	-1.8	-1.7	-1.5	-0.8	-1.3	-1.6	-0.5	-1.5	-1.7	-0.5	-0.3	-1.3	-1.1	-1.5	-1.3	0.0	-0.5	-0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	3.0	-0.7	0.0	-0.2	-0.2	-0.2	-0.3	0.1	0.1	0.0	-0.1	-0.2	-0.0	0.1	-1.2	0.5	0.3	1.2	0.6	-0.5	1.7	1.1	-0.3	1.4	1.2	0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.2	0.3	0.6	0.5	0.8	0.8	0.9	0.8	1.0	1.1	0.9	1.0	0.9	0.8	0.6	0.8	0.9	0.2	0.3	0.9	0.2	0.6	0.7	0.1	0.1	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.0	0.6	0.6	0.6	0.3	0.5	0.5	0.6	0.6	0.5	0.6	0.8	0.6	0.6	-0.2	0.7	0.7	0.8	1.0	0.5	0.9	0.7	0.2	0.6	0.7	0.7
Number of self-reported non-cancer illnesses	0.4	0.7	3.5	-1.9	-0.6	-0.6	-0.9	-0.9	-0.5	-0.8	-0.6	-0.5	-0.4	-0.2	-0.5	-0.7	-0.7	-0.3	-0.5	1.3	1.2	-0.5	0.6	0.9	-1.0	1.0	1.4	0.8
Ever taken oral contraceptive pill	0.4	0.5	2.0	-0.6	-0.9	-0.0	-0.7	-0.4	-0.3	-0.8	-0.4	-0.6	-0.4	-1.2	-0.5	-0.7	0.8	-1.0	-0.3	-0.6	-0.2	-0.2	-1.4	-0.6	-0.4	-1.1	-0.6	-0.6
Medication: Blood pressure	0.4	0.8	1.9	-0.2	1.0	0.5	1.0	0.5	0.8	0.9	0.6	0.8	0.7	0.6	0.7	0.8	-0.2	1.1	1.1	1.2	0.5	0.9	1.4	1.0	0.3	1.2	1.1	1.2
Medication: Paracetamol	0.4	0.7	4.9	-2.2	0.6	0.8	0.8	0.5	0.5	0.5	0.7	0.8	0.4	0.1	0.5	0.5	0.2	0.7	0.5	0.8	0.7	0.5	0.2	1.4	0.4	0.5	1.2	1.2
Alcohol drinker status: Never	0.4	0.4	0.7	-0.5	0.8	0.2	0.8	0.9	0.4	0.7	0.7	0.6	0.9	-0.1	0.7	0.7	0.5	0.9	0.9	0.5	0.6	0.4	0.8	0.6	0.8	-0.0	0.8	0.6
Vascular/heart problems diagnosed by doctor	0.4	1.1	2.9	0.7	1.2	1.0	1.1	1.2	1.3	1.4	1.5	1.4	1.0	1.7	1.1	1.4	0.5	1.2	1.1	0.2	0.3	1.2	0.3	0.8	1.0	0.0	0.1	0.6
Supplements: Calcium	0.4	0.4	1.2	1.1	0.7	-0.0	1.1	0.7	0.2	0.6	0.4	0.8	0.7	-0.3	0.6	0.6	0.5	0.4	0.7	-0.6	-0.7	0.2	-0.9	-0.2	0.8	-0.7	-0.7	-0.2
Reaction Time	0.3	0.5	2.1	1.5	-0.5	-0.1	-0.3	-0.6	-0.8	-0.5	-0.6	-0.5	-0.4	-0.4	-0.8	-0.5	-0.3	-0.7	-0.9	-0.6	-0.6	-0.8	-1.3	-0.7	-0.7	-0.4	-0.9	-1.0
HDL Cholesterol	0.3	0.6	3.4	-1.0	-0.9	-0.9	-0.7	-0.6	-1.1	-0.8	-1.0	-0.7	-0.5	-1.8	-0.9	-0.9	0.1	-0.7	-0.3	0.1	0.6	-0.9	-0.4	-0.2	-0.4	-0.1	0.0	-0.2
Cardiovascular Disease	0.3	0.8	1.5	-1.2	-1.0	-1.1	-1.2	-1.0	-1.1	-1.1	-1.2	-1.0	-1.0	-1.2	-0.9	-1.1	-0.4	-0.7	-0.4	0.6	0.5	-1.1	0.6	-0.2	-0.8	0.8	0.8	0.5
Tanning	0.3	3.4	7.0	1.5	2.1	1.8	1.6	2.5	2.1	2.2	1.9	1.8	2.4	1.9	2.5	2.1	2.6	1.6	1.8	-1.0	-1.2	2.1	-0.0	-0.2	2.6	-1.7	-0.8	-0.3
Diabetes (father)	0.3	0.3	0.9	-0.5	-0.5	0.1	-0.2	-0.8	-0.5	-0.5	-0.5	-0.6	-0.7	-0.3	-0.7	-0.5	-0.9	-0.3	-0.5	0.7	0.5	-0.5	0.1	0.3	-0.9	0.7	0.6	0.5
High blood pressure	0.3	0.9	2.1	-0.0	-1.1	-0.6	-1.1	-1.0	-1.1	-1.2	-1.4	-1.3	-0.9	-1.4	-0.8	-1.3	-0.1	-1.2	-1.0	-0.6	-0.7	-1.0	-0.5	-1.1	-0.7	-0.3	-0.6	-0.8
Stomach or abdominal pain in last month	0.3	0.4	2.1	0.1	0.3	0.9	0.4	0.1	0.9	0.4	0.4	0.5	0.0	1.4	0.5	0.5	-0.3	0.4	0.6	0.8	0.7	0.9	0.5	0.0	-0.1	0.7	0.5	1.0
Waist circumference	0.3	0.9	4.7	0.5	-1.0	-1.1	-2.2	-1.1	-1.0	-1.1	-1.1	-1.1	-1.3	-0.5	-1.0	-1.1	-0.5	-1.0	-1.4	-0.1	-0.1	-1.0	-0.6	-0.8	-1.0	0.2	-0.1	-0.1
Hearing difficulty/problems with background noise	0.3	0.5	2.5	-0.5	0.2	0.3	0.4	0.0	0.8	0.2	0.3	0.2	-0.0	0.7	-0.3	0.3	-0.4	0.5	0.2	1.6	1.5	0.8	0.8	0.6	-0.3	0.9	1.3	1.1
Had other major operations	0.3	0.3	0.8	0.1	-0.8	-0.3	-0.7	-0.5	-0.4	-0.8	-0.7	-0.5	-0.6	-0.6	-0.6	-0.7	0.0	-0.9	-0.3	-0.4	0.0	-0.4	-0.8	-0.7	-0.5	-0.5	-0.5	-0.3
Mouth/teeth dental problems	0.3	0.4	1.4	0.2	-0.4	-0.7	-0.3	-0.3	-0.6	-0.5	-0.4	-0.7	-0.5	-1.2	-0.3	-0.5	0.0	-0.7	-0.7	-1.0	-0.8	-0.6	-1.0	-0.8	-0.1	-0.6	-0.9	-1.0
Heart attack	0.3	0.4	2.1	-0.1	-0.5	-0.2	-0.9	0.0	-0.2	-0.6	-0.3	-0.4	-0.3	-0.8	0.1	-0.5	1.1	-0.8	-0.8	-0.8	-0.8	-0.1	-0.5	-0.8	0.2	-1.4	-0.5	-1.0
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.0	-0.9	-0.0	-0.3	-0.1	-0.3	-0.1	0.0	0.1	0.2	0.0	0.2	-0.1	0.0	-0.4	0.3	-0.1	1.4	1.1	-0.2	0.6	1.2	-0.6	0.6	1.3	0.3
Hair/balding pattern: Pattern 3	0.3	0.4	1.2	-0.3	0.5	0.4	0.4	0.8	0.5	0.6	0.8	0.8	0.9	1.1	0.9	0.6	0.8	0.6	0.6	-0.2	-0.3	0.5	0.2	0.3	0.9	-0.1	0.0	0.3
Mouth/teeth dental problems: Dentures	0.3	0.5	1.8	-0.1	0.5	0.8	0.4	0.4	0.6	0.6	0.5	0.3	0.4	-0.0	0.2	0.6	-0.1	0.8	0.7	1.3	1.3	0.7	0.9	0.5	0.2	0.8	1.3	1.3
Hair/balding pattern: Pattern 4	0.3	0.7	4.6	0.2	0.1	0.1	0.1	0.7	0.6	0.1	0.1	0.2	0.5	0.1	0.6	0.1	2.1	-0.2	-0.4	-1.4	-1.2	0.7	-0.7	-0.7	1.2	-1.9	-1.0	-1.0
Medication: Paracetamol	0.3	0.5	7.3	-2.7	0.0	0.5	0.6	0.3	-0.2	-0.1	0.1	0.2	0.2	-0.6	0.2	-0.0	1.0	0.1	-0.1	0.4	0.3	-0.1	-0.5	0.8	0.4	-0.4	0.8	0.2
Gout (self-reported)	0.3	0.4	1.9	-0.8	0.4	0.9	0.7	0.6	0.7	0.4	0.5	0.4	1.1	1.4	0.6	0.5	0.6	0.4	0.5	0.1	0.2	0.7	0.0	0.4	0.7	-0.2	0.4	0.4
Body fat percentage	0.3	1.2	6.0	0.3	-1.2	-1.1	-2.4	-1.3	-1.1	-1.3	-1.6	-1.7	-1.2	-0.5	-1.2	-1.4	-0.4	-1.0	-1.3	0.1	0.6	-1.0	-0.5	-1.1	-1.1	0.6	0.0	0.2
Worry too long after embarrassment	0.3	0.6	1.7	-1.2	0.8	0.2	1.3	0.6	0.7	0.6	0.8	0.9	0.7	0.8	0.6	0.7	0.5	0.7	0.6	0.9	0.1	0.7	0.1	1.3	0.4	0.1	1.1	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.8	-0.4	-0.0	0.0	-0.0	-0.3	-0.3	-0.0	0.1	0.2	0.1	0.8	-0.3	0.0	-0.7	0.3	0.7	1.0	0.8	-0.4	0.1	1.3	-0.6	0.9	0.9	0.7
Pulse wave peak to peak time	0.3	0.3	1.6	-0.9	-0.0	0.1	-0.0	-0.2	0.3	-0.1	0.1	-0.0	0.1	0.0	-0.2	0.0	-0.7	0.3	0.3	1.1	1.2	0.2	1.0	0.9	-0.4	0.5	1.2	0.7
Qualifications: College or University degree	0.3	0.9	2.3	-0.5	0.6	1.2	0.5	1.2	0.1	0.9	1.0	1.3	0.9	0.7	1.1	0.9	1.3	0.5	0.7	-1.1	-1.5	-0.0	-1.4	0.3	1.3	-1.2	-1.0	-0.8
Eye problems/disorders: None of the above	0.3	0.3	2.1	-1.0	0.1	0.1	0.5	-0.1	-0.1	0.1	0.2	0.3	0.2	-0.6	-0.2	0.1	0.0	0.5	0.2	1.0	0.6	-0.3	0.1	1.5	-0.3	0.7	1.2	0.7
Medication: Ibuprofen	0.3	0.4	1.5	0.4	0.4	0.5	1.0	0.1	0.6	0.4	0.7	0.7	0.2	-0.1	0.1	0.4	-0.8	0.5	0.2	0.6	0.2	0.6	1.1	0.8	-0.2	1.2	0.5	0.8
Age at last live birth	0.3	0.4	2.9	0.5	-0.2	-0.1	-0.2	0.2	-0.0	-0.0	-0.2	0.1	0.5	0.1	0.2	-0.1	1.7	-0.2	-0.1	-1.3	-1.1	0.0	-1.0	-0.4	0.6	-1.0	-1.2	-0.6
Supplements: Vitamin C	0.3	0.4	2.3	1.5	0.4	0.1	0.8	0.2	0.8	0.5	0.4	0.4	0.2	-0.6	0.3	0.4	-0.8	0.5	0.7	0.7	0.1	0.9	0.9	0.3	0.1	0.2	0.4	0.2
Knee pain experienced in last month	0.3	0.4	1.1	-0.4	-0.6	-1.0	-0.8	-0.8	-0.6	-0.6	-1.0	-0.9	-0.7	-0.6	-0.7	-0.8	-0.1	-0.6	-0.7	-0.1	0.1	-0.5	-0.4	-0.9	-0.7	-0.0	-0.2	-0.3
Smoking status: Previous	0.3	0.5	1.6	-0.5	0.5	1.0	0.3	1.0	1.2	0.6	0.8	0.5	0.6	0.2	0.7	0.6	1.3	0.3	-0.0	-0.4	-0.8	1.3	-0.3	-0.3	0.9	-0.7	-0.3	-0.0
Arm fat percentage (left)	0.3	1.2	7.0	0.1	-1.1	-1.2	-2.6	-1.2	-1.0	-1.2	-1.5	-1.5	-1.1	-0.2	-1.0	-1.3	-0.3	-0.9	-1.2	0.4	0.9	-0.9	-0.1	-0.8	-1.0	0.8	0.3	0.5
Loneliness, isolation	0.3	0.5	2.0	-1.0	-0.6	0.6	-0.6	-0.0	-0.7	-0.6	-0.4	-0.6	-0.1	-0.1	-0.0	-0.5	1.4	-0.8	-0.3	-0.7	-0.1	-0.7	-1.0	-1.0	0.3	-1.2	-0.3	-0.6
Long-standing illness, disability or infirmity	0.3	0.5	1.4	-1.2	0.5	0.9	0.5	0.7	0.8	0.5	0.7	0.7	0.7	0.6	0.8	0.6	0.5	0.5	0.8	0.5	0.3	0.8	0.8	0.4	0.7	0.1	0.6	0.7
Qualifications: nursing, teaching	0.3	0.4	1.7	0.4	-0.0	-0.4	-0.1	0.5	0.1	0.1	0.2	0.4	-0.3	1.1	0.3	0.1	0.9	-0.2	0.1	-1.1	-0.7	0.0	-0.9	-0.3	0.6	-1.3	-1.3	-1.1
Mineral and other dietary supplements	0.3	0.4	3.5	-1.9	-0.7	-0.8	-0.5	-0.4	-0.5	-0.7	-0.6	-0.5	-0.5	-0.3	-0.4	-0.7	0.8	-0.6	-0.8	-0.2	-0.0	-0.5	-0.7	-0.2	-0.3	-0.1	0.0	0.3
Illnesses of father: High blood pressure	0.3	0.3	2.5	0.5	0.1	-0.4	-0.2	0.4	0.1	0.1	-0.1	0.0	0.1	-0.1	0.3	0.1	0.9	-0.2	0.1	-0.8	-0.7	0.1	-0.7	-0.7	0.6	-1.6	-0.8	-1.0
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.4	-0.4	0.6	1.2	-0.1	0.8	0.5	0.7	0.7	0.7	0.8	1.1	0.9	0.7	0.6	0.5	0.9	-0.5	-1.0	0.5	-0.4	0.4	0.8	-0.6	-0.4	-0.2
Crohns Disease (2017)	0.2	0.3	1.7	-0.8	-0.5	0.3	-1.0	-0.4	0.2	-0.4	-0.1	0.0	-0.0	1.3	-0.1	-0.3	-0.5	-0.2	-0.5	0.6	0.7	0.1	-0.1	0.6	-0.5	0.6	0.9	1.0
Age at First Birth	0.2	0.3	1.1	0.4	-0.1	-0.0	-0.2	0.3	0.1	0.0	0.2	0.1	-0.1	0.7	0.5	0.1	0.9	-0.3	0.1	-0.8	-0.9	0.1	-1.1	-0.7	0.4	-0.5	-0.8	-0.0
Fasting Glucose	0.2	0.2	2.0	-0.0	0.2	0.6	0.0	-0.1	-0.2	0.1	-0.0	-0.3	-0.1	0.1	-0.0	0.1	0.4	-0.0	0.1	-0.7	-0.4	-0.3	-0.0	0.0	0.1	-1.0	-0.4	-1.4
BMI	0.2	1.2	6.2	1.0	-1.0	-1.1	-2.5	-0.8	-0.8	-1.1	-1.4	-1.4	-1.1	-0.0	-0.7	-1.2	0.5	-1.2	-1.3	-1.0	-0.5	-0.7	-1.4	-1.9	-0.4	-0.6	-1.0	-0.2
Waist Hip Ratio (WHR)	0.2	0.9	3.7	1.9	0.5	0.2	0.6	0.5	0.3	0.3	0.5	0.6	0.1	-0.4	0.4	0.4	0.5	-0.2	-0.9	-1.5	-1.8	0.3	-1.6	-0.8	0.5	-1.4	-1.5	-1.3
Smoking Status	0.2	0.4	1.5	0.0	-0.1	0.2	-0.3	-0.1	-0.2	-0.2	-0.3	-0.2	-0.6	-1.1	-0.2	-0.2	0.2	-0.5	-1.0	-0.9	-1.0	-0.1	-1.2	-1.0	-0.2	-0.9	-1.1	-0.9
Type 2 Diabetes (T2D) (2018)	0.2	0.3	4.3	1.0	0.2	0.8	-0.2	0.2	0.1	0.2	0.1	0.3	0.2	0.4	0.5	0.2	2.1	0.1	0.4	-0.4	-0.8	0.2	-0.4	-0.5	0.5	-0.4	-0.3	0.0
Hair Pigment	0.2	4.9	12.3	0.4	-2.6	-1.9	-2.0	-2.9	-2.2	-2.6	-2.7	-2.5	-3.2	-1.2	-2.7	-2.6	-3.5	-2.6	-2.8	-0.5	0.1	-2.0	-1.2	-1.9	-2.9	0.2	-1.2	-1.4
Systolic blood pressure, automated reading	0.2	0.5	2.9	1.7	-0.4	-0.9	-1.2	-0.7	-0.5	-0.5	-1.0	-1.1	-0.4	-0.4	-0.8	-0.7	-0.6	-0.3	-0.4	0.1	0.2	-0.4	0.6	-0.8	-0.6	0.8	-0.1	0.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	2.2	1.5	0.3	0.0	-0.1	0.3	0.7	0.3	0.4	0.5	0.1	0.6	0.6	0.4	0.3	0.2	0.7	-0.3	-0.4	0.7	0.6	-0.2	0.4	-0.3	-0.4	-0.2
Impedance of leg (right)	0.2	1.0	4.2	0.5	1.1	1.4	2.0	1.2	0.9	1.2	1.1	1.0	1.3	-0.6	0.8	1.2	0.5	0.8	0.8	-0.6	-0.9	0.8	-0.7	0.2	1.0	-1.1	-0.5	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.8	0.5	-0.5	-0.2	-1.2	-0.5	-0.7	-0.5	-0.8	-0.8	-0.5	0.1	-0.4	-0.6	0.9	-0.7	-1.0	-0.8	-0.4	-0.7	-1.2	-1.3	-0.2	-0.8	-0.8	-0.7
Chronic bronchitis/emphysema (father)	0.2	0.2	0.9	0.3	0.3	0.2	0.0	0.1	-0.1	0.1	0.0	-0.1	-0.2	-0.8	0.4	0.0	0.1	-0.1	-0.4	-0.9	-0.8	-0.1	-0.9	-0.7	0.2	-0.6	-0.7	-0.6
Body mass index (BMI)	0.2	0.8	4.3	0.3	-0.8	-1.1	-2.1	-1.0	-0.7	-0.9	-1.2	-1.2	-1.0	-0.0	-0.7	-1.0	-0.3	-0.6	-0.9	0.4	0.7	-0.6	0.1	-0.6	-0.8	1.0	0.4	0.9
Impedance of leg (left)	0.2	0.8	4.3	-0.1	1.1	1.5	2.1	1.1	0.9	1.1	1.1	1.0	1.2	-0.6	0.7	1.1	-0.1	1.0	1.0	0.2	-0.0	0.9	-0.0	0.6	0.8	-0.3	0.3	0.2
Past tobacco smoking	0.2	0.3	1.3	1.1	-0.2	-0.3	0.1	-0.5	-0.6	-0.2	-0.3	-0.0	-0.1	0.2	-0.3	-0.2	-1.1	0.0	0.4	0.5	0.7	-0.8	0.4	0.3	-0.5	0.9	0.4	0.5
Hair/balding pattern: Pattern 2	0.2	0.2	0.8	-0.5	-0.2	0.5	-0.4	-0.5	-0.3	-0.2	-0.5	-0.4	-0.5	0.1	-0.5	-0.3	-0.6	0.0	0.2	0.6	0.7	-0.3	0.4	0.2	-0.5	0.9	0.4	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	2.1	0.3	-0.2	-0.0	-0.9	-0.2	-0.3	-0.3	-0.6	-0.7	-0.3	0.4	-0.1	-0.4	1.3	-0.5	-0.7	-1.0	-0.6	-0.3	-1.1	-1.4	0.0	-0.7	-1.0	-0.5
Qualifications: None of the above	0.2	0.5	2.7	1.6	0.8	0.3	1.1	0.2	0.5	0.7	0.4	0.4	0.3	-0.0	0.3	0.6	-0.9	0.6	0.4	0.6	0.3	0.5	1.1	0.1	0.0	1.1	0.5	0.9
Financial difficulties in last 2 years	0.2	0.3	1.8	-0.5	-0.4	-0.5	-0.3	-0.3	-0.4	-0.6	-0.6	-1.0	-0.5	-0.9	-0.4	-0.6	0.8	-0.6	-0.6	-0.3	0.4	-0.4	0.0	-1.3	-0.2	-0.3	-0.1	-0.0
Diabetes (self-reported)	0.2	0.3	1.2	-0.6	-0.3	-0.3	-0.6	-0.7	-0.5	-0.4	-0.5	-0.4	-0.6	0.0	-0.3	-0.4	0.1	-0.0	0.1	0.9	0.6	-0.5	0.7	0.5	-0.6	1.1	1.0	0.8
Impedance of arm (right)	0.2	0.7	1.8	0.7	-1.1	-0.6	-0.9	-0.8	-0.9	-0.8	-0.8	-0.9	-0.9	-0.9	-1.0	-0.8	-0.7	-0.9	-1.0	-0.6	-0.1	-0.9	-0.9	-0.8	-0.9	-0.6	-0.8	-1.4
Father’s age at death	0.2	0.3	1.2	0.3	-0.5	-0.1	-0.9	-0.6	-0.6	-0.6	-0.6	-0.5	-0.5	-0.2	-0.5	-0.6	-0.0	-0.5	-0.4	-0.2	0.1	-0.7	-1.1	-0.4	-0.6	-0.3	-0.2	-0.2
Noisy workplace	0.2	0.2	1.0	-0.3	-0.0	0.4	-0.0	0.0	0.5	-0.0	0.1	-0.0	-0.2	0.9	0.0	0.1	-0.2	0.2	0.1	0.6	1.0	0.5	0.9	0.4	-0.0	0.6	0.5	0.8
Prospective memory result	0.2	0.2	1.3	-0.3	-0.3	0.2	-0.5	-0.4	-0.3	-0.3	-0.2	-0.1	-0.6	0.5	-0.5	-0.2	-1.2	-0.1	-0.2	0.5	0.8	-0.3	0.1	0.6	-0.5	0.5	0.3	0.2
Pulse wave reflection index	0.2	0.3	0.7	-0.2	-0.4	-0.4	-0.2	-0.6	-0.8	-0.5	-0.5	-0.5	-0.7	-0.6	-0.5	-0.5	-0.5	-0.4	-0.5	0.3	0.8	-0.8	-0.1	-0.1	-0.6	0.6	0.2	0.2
Headache pain in last month	0.2	0.3	0.7	0.3	0.4	-0.2	0.5	0.0	0.7	0.3	0.4	0.5	0.0	0.8	0.4	0.4	-0.8	0.4	0.3	0.8	0.5	0.6	0.4	0.7	-0.2	0.7	0.8	0.8
Neck or shoulder pain in last month	0.2	0.4	1.0	-0.3	0.6	0.0	0.8	0.0	0.7	0.5	0.5	0.3	0.3	0.1	0.4	0.5	-0.7	0.7	0.7	0.9	0.6	0.6	1.0	0.9	-0.2	0.6	0.9	0.3
Medication: Allopurinol	0.2	0.3	1.6	-0.2	0.1	0.3	0.0	0.5	0.1	0.1	0.2	0.1	0.7	0.7	0.4	0.1	0.7	-0.1	-0.2	-0.8	-0.7	0.2	-0.6	-0.1	0.8	-1.3	-0.5	-0.8
Mean time to correctly identify matches	0.2	0.3	2.4	1.5	-0.2	0.1	-0.4	-0.3	-0.4	-0.2	-0.3	-0.2	-0.1	0.2	-0.4	-0.2	-0.1	-0.4	-0.8	-0.7	-0.6	-0.3	-1.1	-0.6	-0.3	-0.6	-1.0	-0.9
Hypertension (Self-reported)	0.2	0.5	1.3	0.1	-0.8	-0.6	-1.0	-0.8	-0.9	-1.0	-1.1	-1.0	-0.8	-1.1	-0.7	-1.0	-0.1	-0.9	-0.7	-0.1	-0.3	-0.8	-0.0	-0.7	-0.7	0.2	-0.1	-0.2
Osteoporosis (self-reported)	0.2	0.2	1.1	-1.0	-0.1	-0.9	-0.2	-0.3	-0.2	-0.1	-0.2	-0.0	0.3	-1.0	-0.2	-0.2	-0.1	0.0	0.4	0.3	0.5	-0.3	0.2	0.4	-0.2	0.6	0.4	0.6
Osteoarthritis (self-reported)	0.2	0.2	1.1	0.3	-0.3	-0.2	0.2	0.2	0.1	-0.3	0.4	0.4	-0.2	0.5	0.2	-0.1	0.4	-0.6	-0.4	-0.8	-0.8	0.1	-0.6	-0.4	0.3	-1.0	-0.8	-0.7
Guilty feelings	0.2	0.4	1.5	-0.7	0.2	0.6	0.3	0.6	1.2	0.2	0.8	0.7	0.3	0.8	0.5	0.4	0.7	0.2	0.5	0.3	0.2	1.2	0.0	0.3	0.5	-0.0	0.6	1.1
Wears glasses or contact lenses	0.2	0.2	1.2	-1.0	0.2	0.3	0.6	0.3	0.3	0.2	0.3	0.4	0.6	0.3	0.3	0.2	1.1	0.2	0.1	0.0	-0.2	0.3	0.3	0.2	0.5	-0.1	0.1	0.2
Average weekly beer plus cider intake	0.2	0.3	1.4	-0.2	0.1	0.3	0.1	0.0	0.4	0.1	0.0	-0.1	0.2	-0.3	-0.1	0.0	0.5	0.3	0.6	0.9	0.8	0.5	1.2	0.1	0.1	1.0	0.9	1.1
Irritability	0.2	0.4	0.9	0.0	0.6	0.8	1.0	0.8	0.8	0.7	0.7	0.8	0.5	0.8	0.7	0.7	0.6	0.4	0.7	0.0	-0.7	0.9	0.2	-0.1	0.8	-0.6	0.0	0.0
Diastolic blood pressure, automated reading	0.2	0.6	3.1	1.0	0.4	-0.0	-0.7	-0.3	0.0	0.3	-0.3	-0.4	0.2	0.0	-0.1	0.1	-0.7	0.7	0.3	1.3	1.1	0.1	1.6	0.4	-0.3	1.8	1.2	1.5
Schizophrenia vs Biploar Disorder	0.1	0.1	1.1	-0.2	-0.2	0.2	0.1	-0.3	0.1	-0.1	-0.2	-0.4	-0.1	-0.3	-0.1	-0.1	-0.7	-0.0	-0.2	0.5	1.0	0.1	0.7	0.1	-0.3	0.5	0.2	0.1
Breast Cancer	0.1	0.3	2.3	1.5	-0.2	-0.4	-0.5	-0.3	0.3	-0.1	-0.2	0.0	-0.3	1.4	-0.1	-0.1	-0.4	-0.2	0.1	-0.1	-0.0	0.3	0.4	-0.8	-0.3	0.6	-0.2	0.6
Primary Biliary Cirrhosis	0.1	0.2	1.6	-0.3	-0.1	-0.5	-0.6	0.1	-0.4	-0.2	-0.2	0.0	-0.0	0.1	0.1	-0.2	0.9	-0.3	-0.5	-0.3	-0.5	-0.5	-1.3	-0.4	0.2	-0.5	-0.3	0.1
Blood Platelet Count	0.1	0.8	2.6	1.6	1.2	0.4	0.4	1.1	1.2	1.2	0.9	0.8	0.9	1.4	1.0	1.1	0.2	1.0	1.1	-0.3	-0.4	1.3	-0.2	-0.3	1.2	-0.0	-0.3	0.5
Medication for hormone replacement therapy	0.1	0.1	0.6	-0.3	-0.4	-0.2	-0.6	-0.2	-0.1	-0.3	0.2	0.2	-0.5	0.0	-0.1	-0.2	-0.8	-0.4	-0.3	0.1	0.2	-0.1	-0.0	0.3	-0.4	-0.3	-0.1	-0.6
Supplements: Zinc	0.1	0.1	0.2	0.2	0.3	0.2	0.2	0.3	0.4	0.3	0.2	0.2	0.2	-0.3	0.2	0.3	0.1	0.3	0.3	-0.2	-0.1	0.5	-0.0	-0.2	0.4	-0.2	-0.2	-0.0
Current tobacco smoking	0.1	0.1	0.5	0.4	0.7	0.1	0.7	0.3	0.3	0.5	0.2	0.5	0.3	-0.3	0.4	0.4	0.2	0.3	0.0	-0.1	-0.1	0.3	-0.5	-0.3	0.3	-0.2	-0.4	-0.0
Supplements: Glucosamine	0.1	0.1	0.5	0.7	-0.3	0.2	-0.6	-0.3	-0.0	-0.2	-0.0	-0.2	0.0	-0.1	-0.2	-0.2	-0.2	-0.2	-0.2	0.3	0.4	-0.0	0.0	-0.3	-0.3	0.5	0.2	0.5
High blood pressure (mother)	0.1	0.1	0.6	0.3	-0.1	-0.5	-0.3	-0.3	-0.7	-0.4	-0.4	-0.2	-0.3	-0.8	-0.1	-0.4	0.0	-0.3	-0.2	-0.2	-0.4	-0.7	-0.3	-0.0	-0.2	-0.2	-0.0	-0.2
Illnesses of siblings	0.1	0.2	1.0	0.4	-0.3	-0.6	0.0	-0.3	0.1	-0.2	-0.0	0.0	-0.3	0.2	-0.2	-0.1	-0.6	-0.1	0.1	0.6	0.3	-0.0	0.1	0.0	-0.4	0.9	0.4	1.0
Pulse rate	0.1	0.1	1.3	-1.1	0.0	0.8	-0.3	0.1	0.4	0.2	0.3	0.1	0.0	0.0	0.3	0.2	0.1	0.2	0.1	0.4	0.0	0.4	0.3	0.2	-0.0	0.2	0.4	0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.0	-1.0	-0.8	-0.4	-0.6	-0.1	-0.5	-0.6	-0.4	-0.4	-0.8	-0.7	-0.2	-0.5	0.2	-0.6	-0.3	-0.6	-0.0	-0.4	-0.9	-0.8	0.0	-0.5	-0.7	-0.2
Impedance of arm (left)	0.1	0.3	1.7	1.0	-0.5	0.1	-0.2	-0.1	-0.2	-0.2	-0.1	-0.3	-0.2	-0.5	-0.4	-0.2	-0.1	-0.5	-0.4	-0.7	-0.2	-0.2	-0.7	-0.6	-0.2	-0.9	-0.8	-1.3
Medication: Amlodipine	0.1	0.2	0.9	0.3	0.3	0.7	-0.5	0.3	0.4	0.3	0.2	-0.0	0.4	0.1	0.5	0.3	1.0	0.3	0.6	0.1	-0.0	0.4	0.6	-0.2	0.5	-0.5	0.1	-0.4
Medication for pain relief, constipation, heartburn	0.1	0.2	1.7	1.3	0.2	-0.2	-0.6	-0.1	0.1	0.3	0.1	0.1	-0.2	1.3	0.1	0.3	-0.9	0.3	0.5	0.3	0.2	0.1	0.3	-0.0	-0.3	0.7	-0.0	0.3
Comparative height size at age 10	0.1	0.8	3.7	0.8	-0.3	-0.1	-1.0	-0.1	-0.4	-0.4	-0.2	0.0	-0.2	-0.1	-0.1	-0.3	0.6	-0.8	-0.9	-1.5	-1.8	-0.4	-1.4	-0.5	-0.0	-1.5	-1.5	-1.9
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	1.1	-0.3	-0.2	0.2	-0.4	-0.0	-0.2	-0.4	-0.3	-0.4	-0.1	-0.3	-0.3	-0.4	1.1	-0.4	-0.5	-0.4	-0.6	-0.1	-0.1	-0.2	0.1	-0.5	-0.1	-0.3
Average weekly red wine intake	0.1	0.1	0.9	0.4	-0.0	-0.2	-0.5	-0.0	0.1	0.1	0.2	0.5	-0.2	1.0	0.2	0.1	-0.4	0.0	-0.1	-0.2	-0.3	0.1	-0.3	-0.1	-0.1	0.2	-0.2	0.2
Diabetes diagnosed by doctor	0.1	0.1	0.7	0.3	0.0	0.3	-0.3	-0.4	-0.3	-0.1	-0.3	-0.1	-0.2	0.2	0.0	-0.1	0.8	0.1	0.3	0.3	-0.2	-0.3	0.3	0.3	-0.2	0.6	0.3	0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	1.3	0.2	-0.0	0.2	-0.4	-0.1	-0.0	0.1	-0.1	0.4	-0.2	1.2	0.0	0.0	-0.4	-0.2	0.0	-0.2	-0.4	0.1	-0.4	-0.5	-0.2	-0.3	-0.4	-0.4
Smoking status: Current	0.1	0.2	0.9	-0.0	-0.1	-0.6	-0.2	-0.6	-0.5	-0.3	-0.7	-0.5	-0.6	-0.9	-0.5	-0.4	-0.5	-0.3	-0.7	0.0	0.3	-0.5	-0.6	-0.7	-0.6	0.1	-0.3	-0.2
Tinnitus: Yes, now most or all of the time	0.1	0.2	1.6	0.1	0.2	0.1	0.3	-0.0	0.1	0.1	0.3	0.4	0.2	-0.4	0.1	0.2	0.0	0.3	0.1	0.5	0.6	0.0	0.6	1.3	-0.3	0.5	0.6	0.2
High cholesterol (Self-reported)	0.1	0.2	0.9	0.1	0.2	-0.1	-0.4	0.2	-0.6	-0.0	-0.2	-0.0	0.1	0.4	0.2	-0.1	1.0	-0.1	0.1	-0.7	-1.0	-0.6	-0.3	-0.4	0.4	-0.4	-0.5	-0.4
Medication: Atorvastatin	0.1	0.1	0.6	-0.8	0.3	0.1	0.4	0.4	0.3	0.2	0.3	0.3	0.6	0.1	0.4	0.2	0.7	0.1	-0.1	-0.2	-0.1	0.2	-0.0	0.0	0.5	-0.5	-0.1	-0.1
Leg fat percentage (left)	0.1	0.3	1.9	-0.4	0.0	-0.0	-1.0	-0.3	-0.0	-0.1	-0.6	-0.6	-0.1	0.1	-0.2	-0.3	-0.1	0.2	-0.2	0.9	1.0	0.1	0.4	-0.1	-0.2	1.1	0.9	1.4
Number of operations (self-reported)	0.1	0.2	0.7	0.1	0.6	0.2	0.9	0.4	0.7	0.5	0.3	0.6	0.4	0.4	0.6	0.4	0.5	0.5	0.6	0.3	-0.3	0.8	0.2	0.3	0.3	-0.2	0.3	0.2
Commuting to job workplace: Cycle	0.1	0.1	0.9	0.1	-0.1	-0.5	0.3	-0.4	-0.4	-0.1	-0.2	0.1	-0.3	-0.6	-0.4	-0.2	-1.0	-0.2	0.2	0.0	-0.2	-0.5	-0.1	-0.4	-0.5	0.1	-0.2	-0.5
Basal cell carcinoma (self-reported)	0.1	0.2	0.8	-0.4	-0.4	-0.3	0.4	-0.3	0.1	-0.2	-0.0	-0.1	-0.3	0.6	-0.2	-0.2	-0.1	-0.2	-0.8	0.1	0.5	0.1	-0.2	-0.0	-0.6	0.9	0.0	0.7
Heart disease (siblings)	0.1	0.1	0.9	0.5	-0.2	0.4	-0.5	-0.1	-0.1	-0.1	-0.4	-0.4	-0.1	-0.5	-0.2	-0.2	0.2	-0.2	-0.9	0.0	0.1	-0.0	-0.3	-0.7	-0.1	-0.4	-0.1	-0.4
Impedance of whole body	0.1	0.3	1.3	0.9	0.4	1.0	1.1	0.6	0.5	0.6	0.6	0.5	0.6	-0.3	0.2	0.6	-0.1	0.3	0.3	-0.5	-0.4	0.4	-0.5	-0.1	0.4	-0.7	-0.5	-0.7
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.8	-0.3	-0.2	0.2	-0.9	-0.2	-0.4	-0.2	-0.3	-0.3	-0.2	0.4	-0.1	-0.3	0.2	-0.2	0.0	-0.4	-0.3	-0.4	-0.6	-0.3	-0.1	-0.2	-0.4	-0.2
Blood Red Count	0.0	0.5	1.6	0.2	-0.6	-0.3	-0.1	-0.6	-0.6	-0.7	-0.8	-0.7	-0.4	-0.2	-0.8	-0.7	0.0	-0.8	-1.3	-0.9	-0.7	-0.5	-1.1	-1.0	-0.6	0.0	-0.9	-0.3
High blood pressure (siblings)	0.0	0.1	0.3	-0.3	0.2	-0.1	-0.2	0.2	-0.1	0.2	-0.1	-0.1	0.2	0.2	0.1	0.1	0.2	0.1	0.3	-0.4	-0.5	-0.1	0.0	-0.1	0.3	-0.0	-0.4	-0.3
Leg fat percentage (right)	0.0	0.2	1.0	0.0	-0.0	-0.1	-1.0	-0.3	-0.1	-0.2	-0.6	-0.6	-0.1	0.0	-0.2	-0.3	0.2	-0.0	-0.4	0.3	0.4	-0.0	-0.1	-0.5	-0.2	0.5	0.3	0.7

Hub : Genes

COG6

Models

Trait associations