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chr15:71,418,503-73,263,405

Best TWAS P=3.39e-24 · Best GWAS P=1.11e-21 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Breast Mammary Tissue	MYO9A	0.19	0.02	lasso	8	0.03	9.4e-03	7.7	-10.1	3.4e-24	-0.56	0.05	0.86	TRUE
10	GTEx	Nerve Tibial	PARP6	0.09	0.07	lasso	11	0.06	7.2e-05	8.9	8.9	4.0e-19	0.90	0.06	0.90	TRUE
12	GTEx	Thyroid	PARP6	0.23	0.02	enet	21	0.07	9.0e-06	9.0	8.0	1.4e-15	0.73	0.23	0.75	TRUE
11	GTEx	Stomach	MYO9A	0.17	0.06	lasso	5	0.01	1.1e-01	7.9	-7.9	2.7e-15	-0.18	0.60	0.02	TRUE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	NR2E3	0.03	0.06	lasso	1	0.05	3.8e-06	7.3	-7.3	2.5e-13	-0.14	0.00	0.99	TRUE
8	GTEx	Lung	PARP6	0.09	0.03	lasso	5	0.01	8.1e-02	7.5	5.2	1.6e-07	0.04	0.43	0.02	TRUE
7	GTEx	Colon Transverse	MYO9A	0.13	0.06	lasso	4	0.09	7.0e-05	-1.8	-5.2	2.3e-07	-0.11	0.24	0.04	TRUE
9	GTEx	Nerve Tibial	MYO9A	0.13	0.13	lasso	3	0.11	2.1e-08	7.5	-9.1	1.1e-19	-0.44	0.92	0.08	FALSE
13	The Cancer Genome Atlas	Esophageal Carcinoma	SENP8	0.30	0.04	enet	22	0.12	1.2e-04	7.8	-8.2	3.4e-16	-0.58	0.01	0.39	FALSE
16	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NR2E3	0.07	0.02	blup	38	0.05	4.4e-03	7.2	-7.9	3.7e-15	-0.22	0.03	0.10	FALSE
1	GTEx	Adipose Subcutaneous	MYO9A	0.06	0.03	lasso	2	0.01	4.7e-02	7.7	-7.7	9.4e-15	-0.20	0.34	0.15	FALSE
2	GTEx	Artery Tibial	MYO9A	0.07	0.08	enet	11	0.09	2.5e-07	7.8	-7.3	3.6e-13	-0.13	1.00	0.00	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	MYO9A	0.13	0.08	lasso	3	0.08	1.7e-03	7.5	-7.2	5.8e-13	-0.15	0.63	0.02	FALSE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NR2E3	0.05	0.04	lasso	2	0.03	2.7e-04	5.9	-6.0	1.9e-09	-0.07	0.22	0.02	FALSE
3	GTEx	Brain Cerebellum	MYO9A	0.18	0.12	lasso	2	0.06	6.3e-03	5.9	-5.9	2.9e-09	-0.14	0.11	0.11	FALSE
6	GTEx	Cells Transformed fibroblasts	MYO9A	0.06	0.04	lasso	5	0.03	3.8e-03	5.2	-5.2	2.1e-07	0.05	0.64	0.02	FALSE