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chr17:39,589,083-41,418,334

Best TWAS P=7.69e-09 · Best GWAS P=6.89e-12 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MLX	0.03	0.03	enet	12	0.02	6.5e-04	-4.5	-5.8	7.7e-09	0.87	0.04	0.94	TRUE
5	GTEx	Artery Coronary	RP11-400F19.6	0.15	0.02	lasso	3	0.03	4.1e-02	-5.9	5.6	1.7e-08	-0.87	0.06	0.38	TRUE
3	GTEx	Adipose Subcutaneous	HSD17B1P1	0.06	0.09	enet	6	0.09	4.0e-08	-4.4	-5.5	4.0e-08	0.72	0.92	0.07	TRUE
11	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	TUBG2	0.09	0.01	blup	29	0.03	1.9e-02	4.9	-5.4	6.5e-08	0.75	0.02	0.41	TRUE
8	GTEx	Skin Sun Exposed Lower leg	HSD17B1P1	0.07	0.03	lasso	3	0.02	5.2e-03	5.2	-5.3	1.1e-07	0.68	0.23	0.61	TRUE
9	YFS	Blood	STAT5B	0.04	0.02	lasso	3	0.02	4.2e-06	5.2	5.2	2.1e-07	-0.19	0.94	0.01	TRUE
12	The Cancer Genome Atlas	Thyroid Carcinoma	CNTNAP1	0.04	0.03	blup	27	0.05	2.7e-05	-6.9	5.8	7.9e-09	-0.93	0.01	0.99	FALSE
6	GTEx	Brain Cerebellum	HSD17B1P1	0.17	0.16	lasso	4	0.20	1.7e-06	-4.6	-5.7	1.5e-08	0.86	0.13	0.81	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	CNTNAP1	0.06	0.05	blup	27	0.03	7.3e-03	-5.0	5.6	2.1e-08	-0.86	0.01	0.92	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	HSD17B1	0.14	0.13	enet	8	0.12	8.9e-05	4.9	-5.6	2.4e-08	0.70	0.11	0.67	FALSE
4	GTEx	Adipose Visceral Omentum	HSD17B1P1	0.09	0.06	lasso	3	0.05	1.7e-03	5.2	-5.5	4.8e-08	0.56	0.14	0.42	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RAB5C	0.21	0.18	bslmm	326	0.18	8.1e-21	4.2	5.2	1.7e-07	-0.25	0.25	0.68	FALSE